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Locomotor activity as the leading factor of psychophysical preparation of young students

100%

Panhelova N.

Prace Naukowe Akademii im. Jana Długosza w Częstochowie. Kultura Fizyczna

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2018

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tom 17

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nr 1

The article presents data on the current state of health, physical preparedness, motor activity of students in non-sports profile higher education establishments. It was found that low levels of physical condition of students is determined by a number of factors, among which, the lack of their motor activity, as well as non-rational approaches of the governing bodies and the administration of some higher educational establishments to organizing teaching and extracurricular physical training of future specialists are the major ones. It contains data relative to the main functions of motor activity. The basic provisions of the letter of the Ministry of Education and Science of Ukraine of 09.25.2015 №1 / 9–454 “Regarding the organization of physical education in higher education”.

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Effect of light-dark changes on the locomotor activity in open field in adult rats and opossums

100%

Klejbor I., Ludkiewicz B., Turlejski K.

Folia Morphologica

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2013

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tom 72

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nr 4

There have been no reports on how the light-dark changes determine the locomotor activity of animals in the group of high reactivity (HR) and low reactivity (LR). In the present study we have compared selected parameters of the locomotor activity of the HR and the LR groups of the laboratory opossums and Wistar rats during consecutive, light and dark phases in the open field test. Sixty male Wistar adult rats, at an average weight of 350 g each, and 24 adult Monodelphis opossums of both sexes at an average weight of 120 g each were used. The animals’ activity for 2 h daily between the hours of 17:30 and 19:30, in line with the natural light-dark cycle were recorded and then analysed using VideoTrack ver. 2.0 (Vievpoint France). According to our results, we noted that a change of the experimental conditions from light to dark involves an increase in the locomotor activity in rats and opossums of the HR group, while there is no effect on the activity of the rats and opossums in the LR group. Locomotor activity in the HR rats, both in the light and dark conditions is characterised by a consistent pattern of change — higher activity in the first stage of the recording and a slowdown (habituation) in the second phase of the observation. The locomotor activity of the opossum, during both light and dark conditions, was observed to be at a consistently high level compared to the rats. (Folia Morphol 2013; 72, 4: 300–305)

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Opposite influence of MPEP, an mGluR5 antagonist, on the locomotor hyperactivity induced by PCP and amphetamine

100%

Pietraszek M., Rogoz Z., Wolfarth S., Ossowska K.

Journal of Physiology and Pharmacology

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2004

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tom 55

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nr 3

Potential antipsychotic effects of a selective non-competitive antagonist of metabotropic glutamate receptor 5 (mGluR5), 2-methyl-6-phenylethynylpyridine (MPEP), was examined in two commonly used screening tests: (1) the hyperactivity induced by an NMDA receptor antagonist phencyclidine (PCP), and (2) the hyperactivity induced by an indirect dopamine agonist, D-amphetamine. PCP was administered at a dose of 2.5 mg/kg s.c. and D-amphetamine was given at a dose of 1 mg/kg s.c. MPEP (5 mg/kg i.p.) significantly enhanced the locomotor activity increased by PCP, but inhibited amphetamine-induced hyperactivity. The opposite effect of MPEP in the two above-mentioned models questions significance of the blockade of mGluR5 receptors to antipsychotic effects.

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Effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the behavioral effects of cocaine in rats

100%

Filip M., Antkiewicz-Michaluk L., Zaniewska M., Frankowska M., Golda A., Vetulani J., Przegalinski E.

Journal of Physiology and Pharmacology

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2007

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tom 58

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nr 4

The efficacy of 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), a member of endogenous tetrahydroisoquinolines, in cocaine- and food-maintained responding in self-administration procedures under a fixed ratio 5 schedule of reinforcement as well as in cocaine and food seeking behaviors in male Wistar rats was examined. The effects of 1MeTIQ on cocaine discrimination and on basal locomotor activity were also assessed. In rats trained to self-administered either cocaine (0.5 mg/kg/injection) paired with the cue (light+tone) or food under a fixed ratio 5 schedule of reinforcement, 1MeTIQ (25 - 50 mg/kg) dose-dependently decreased the cocaine-maintained responding, but did not alter the food-maintained responding. 1MeTIQ (25 - 50 mg/kg) decreased the cocaine seeking behavior reinstated by a noncontingent presentation of cocaine (10 mg/kg, i.p.), but altered neither behavior reinstated by a discrete cue (tone+light) nor food-induced reinstatement. In rats trained to discriminate cocaine (10 mg/kg) from saline in water-reinforced fixed ratio 20 task, pretreatment with 1MeTIQ resulted in neither substitution nor significant alterations in the cocaine (1.25 - 10 mg/kg)-induced discriminative stimulus effects. 1MeTIQ (25 - 50 mg/kg) did not produce also a significant changes in basal horizontal activity. In conclusion, our present results outline a significance of exogenously applied 1MeTIQ in attenuating drug-evoked relapses to cocaine as well as the direct rewarding properties of cocaine (that model the cocaine-induced "high"), but not cocaine subjective effects. Moreover, a dissociation between effects of 1MeTIQ on cocaine vs. food-maintained responding was demonstrated.

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Locomotory activity and ion transport in the epithelium of terrestrial snails

84%

Tyrakowski T., Kaczorowski P., Pawlowicz W., Ziolkowski M., Kopczynska E., Lampka M., Holynska-Iwan I., Piskorska E., Stevesandt M.

Folia Malacologica

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2012

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tom 20

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nr 1

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Daily locomotory activity of Mesidotea (Saduria) entomon (L.) (Isopoda, Crustacea) from the Gulf of Gdansk

84%

Szaniawska A., Romanska G.

Oceanologia

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1990

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tom 28

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Involvement of the monoaminergic system in the antidepressant-like activity of chromium chloride in the forced swim test

84%

Piotrowska A., Siwek A., Wolak M., Pochwat B., Szewczyk B., Opoka W., Poleszak E., Nowak G.

Journal of Physiology and Pharmacology

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2013

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tom 64

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nr 4

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Studies on central effects of [Lys1]-proctolin an analogue of proctolin (PR)

84%

Jedrusiak J., Plech A., Brus R., Sobotka W., Konopinska D.

Bulletin of the Polish Academy of Sciences. Biological Sciences

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1991

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tom 39

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nr 1

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Locomotor activity and behavior of mutant mice deleted for gastrin gene expression

84%

Singh P., Cobb S., Rengifo-Cam W., Deng X., Willis W., Li Q.

Journal of Physiology and Pharmacology

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2004

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tom 55

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nr 1,2

The current studies were initiated to investigate the role of brain-gut peptide, gastrin, on locomotor activity and anxiety-like behavior. Young, male mutant mice, lacking gastrin gene expression (GAS-KO mice), were used in the experiments. The locomotor activity of GAS-KO vs wild type (WT) mice was compared by open field test. The anxiety-like behavior was examined using elevated plus maze. The time and entries to the open arms of the elevated plus maze were used as an indicator for the anxiety-like behavior and the data were analyzed using Hindsight program. On the open field test, locomotor activity of GAS-KO mice was similar to that of the WT mice for the first 10 min of the test, but decreased significantly after that. Anxiety-like behavior was more evident in the GAS-KO vs WT mice in the elevated plus maze experiments. The number of entries to and time spent on the open arms of plus-maze were significantly reduced for the GAS-KO vs WT mice suggesting an increased anxiety-like behavior of GAS-KO mice. Our studies suggest that normal circulating levels of gastrins may play a direct or indirect role in the regulation of locomotor activity and anxiety-like behavior.

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Object recognition is not impaired in old rats

84%

Lukaszewska I., Radulska A.

Acta Neurobiologiae Experimentalis

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1994

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tom 54

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nr 2

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Blockade on NMDA receptors in postnatal period decreased density of tyrosine hydroxylase immunoreactive axonal arbors in the medial prefrontal cortex of adult rats

84%

Wedzony K., Fijal K., Chocyk A.

Journal of Physiology and Pharmacology

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2005

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tom 56

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nr 2

Malfunction of glutamatergic neurotransmission in postnatal period is considered to be a risk factor for development of schizophrenia. Thus, the present study investigates the impact of NMDA receptor blockade in the postnatal period on the density of tyrosine hydroxylase immunoreactive axonal arbors in the rat medial prefrontal cortex. Behavioral experiments revealed that adult rats (60 days old) treated in the postnatal period with a competitive antagonist of NMDA receptors, CGP 40116 (1.25 mg/kg on days 1, 3, 6, 9; 2.5 mg/kg on days 12, 15, 18; and finally 5 mg/kg on day 21, all injections s.c.), showed enhancement of the locomotor activity stimulated by quinpirole (0.3 mg/kg s.c.) and amphetamine (0.5 mg/kg s.c.), which suggests development of functional supersensitivity of dopaminergic systems. It has been found that CGP 40116, given in postnatal period decreased the density of tyrosine hydroxylase immunoreactive axonal arbors in the medial prefrontal cortex of adult animals. The decrease was observed in superficial (II/III) and deep (V/VI) layers of the medial prefrontal cortex, while the average length of tyrosine hydroxylase immunoreactive axonal arbors was increased in both superficial and deep cortical layers. Changes in the density of tyrosine hydroxylase immunoreactive axonal arbors have not been followed by a significant decrease in the content of tyrosine hydroxylase protein measured by Western blot. Thus, NMDA receptor blockade in the early period of life evokes changes in architecture of tyrosine hydroxylase immunoreactive axonal arbors and that malfunction of glutamatergic neurotransmission, in early period of life may produce anatomical changes which resemble those observed in the brains of schizophrenics.

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The effect of dorsal raphe nucleus [DRN] lesions on the locomotor activity rhythm in mice

84%

Barbacka-Surowiak G., Gut M.

Folia Biologica

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2001

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tom 49

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nr 1-2

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On the role of serotonin2A-2C receptors in the sensitization to cocaine

84%

Filip M., Nowak E., Papla I.

Journal of Physiology and Pharmacology

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2001

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tom 52

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nr 3

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Involvement of some 5-HT receptors in methamphetamine-induced locomotor activity in mice

84%

Ginawi O. T., Al-Majed A. A., Al-Suwailem A. K., El-Hadiyah T. M. H.

Journal of Physiology and Pharmacology

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2004

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tom 55

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nr 2

Effects of some selective 5-HT antagonists on methamphetamine-induced locomotor activity were investigated in male mice in order to study whether this effect of methamphetamine is selectively or at least partially, induced through stimulation of a specific serotonin receptor subtype. Methamphetamine (1.5mg/kg, IP) produced a significant increase in locomotor activity. Methamphetamine-induced hyperactivity by the above mentioned dose was signficantly antagonized by NAN-190 ( 5-HT1A antagonist) at a dose of 4 mg/kg, IP, methiothepin (5-HT1B/1D antagonist) at a dose of 0.1mg/kg, IP or mianserin ( 5-HT2C antagonist) at a dose of 8mg/kg, IP. On the other hand, methysergide ( 5-HT 2A/2B antagonist) at a dose of 1mg/kg, IP or ondansetron ( 5-HT3 antagonist) at a dose of 0.5mg/kg, IP potentiated the methamphetamine-induced hyperactivity. None of the above mentioned doses of 5-HT antagonists altered the spontaneous activity of mice when administered alone. The results of the present study indicate a possible role for serotonergic mechanisms, in addition to the catecholaminergic systems, in the locomotor stimulant activity of methamphetamine in mice. This role is possibly mediated through direct stimulation of some 5-HT receptor subtypes. Stimulation by methamphetamine of 5-HT 1A, 5-HT 1B/1D and/or 5-HT2C receptor subtypes may result in hyperactivity, whereas stimulation by methamphetamine of 5-HT 2A/2B and/or 5-HT3 receptor subtypes may result in decreased activity.

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Does the reduction of locomotor activity serve as an aggression avoidance mechanism in shrews [Soricidae]?

84%

Zwolak R., Rychlik L.

Electronic Journal of Polish Agricultural Universities. Series Biology

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2004

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tom 07

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nr 2

The hypothesis, that shrews avoid intra- and interspecific aggression through a reduction of their loco-motor activity, was tested. In 55 neutral arena tests (each of 30-min-duration), 10 subadult individuals of Sorex minutus, 14 of S. araneus, 9 (including 1 adult male) of Neomys anomalus, and 13 of N. fodiens were used. Loco-motor activity and sum of conflicts (attacks, chases, escapes and threats) in 1st-5th minutes of interactions (phase I) and 10th-15th minutes (phase II) were compared. In all the species, both in intra- and interspecific interactions, a reduction of mobility between phases I and II was observed (in 6 out of 16 comparisons the difference was statistically significant, and in the 7th comparison it was fairly significant). The highest reduction of activity was observed in the smallest S. minutus, and the lowest reduction (no difference was significant) in the largest, dominating N. fodiens.

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Strain-specific differences in modulatory effects of morphine on peritoneal inflammation in mice

84%

Natorska J., Plytycz B.

Folia Biologica

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2005

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tom 53

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nr 3-4

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Behavioural responsiveness to amphetamine or scopolamine following repeated exposure to chlorphenvinphos in rats

84%

Gralewicz S., Lutz P., Tomas T.

Acta Neurobiologiae Experimentalis

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2002

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tom 62

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nr 2

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Diet- and fasting-induced changes of adrenal medulla activity and its influence on locomotor activity of rats

84%

Beszczynska B.

Acta Biologica Cracoviensia. Series Zoologia

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2004

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tom 46

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6-OHDA bilateral lesions to the central amygdala do not affect vasopressin improvement of recall in rats

84%

Winnicka M. M.

Acta Neurobiologiae Experimentalis

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1996

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tom 56

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nr 4

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Memory effects of arginine vasopressin [AVP] and [7-9] fragment of its peptide chain in rats

84%

Klimkiewicz T.

Acta Neurobiologiae Experimentalis

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2001

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tom 61

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nr 4

Ograniczanie wyników

Locomotor activity as the leading factor of psychophysical preparation of young students

Effect of light-dark changes on the locomotor activity in open field in adult rats and opossums

Opposite influence of MPEP, an mGluR5 antagonist, on the locomotor hyperactivity induced by PCP and amphetamine

Effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the behavioral effects of cocaine in rats

Locomotory activity and ion transport in the epithelium of terrestrial snails

Daily locomotory activity of Mesidotea (Saduria) entomon (L.) (Isopoda, Crustacea) from the Gulf of Gdansk

Involvement of the monoaminergic system in the antidepressant-like activity of chromium chloride in the forced swim test

Studies on central effects of [Lys1]-proctolin an analogue of proctolin (PR)

Locomotor activity and behavior of mutant mice deleted for gastrin gene expression

Object recognition is not impaired in old rats

Blockade on NMDA receptors in postnatal period decreased density of tyrosine hydroxylase immunoreactive axonal arbors in the medial prefrontal cortex of adult rats

The effect of dorsal raphe nucleus [DRN] lesions on the locomotor activity rhythm in mice

On the role of serotonin2A-2C receptors in the sensitization to cocaine

Involvement of some 5-HT receptors in methamphetamine-induced locomotor activity in mice

Does the reduction of locomotor activity serve as an aggression avoidance mechanism in shrews [Soricidae]?

Strain-specific differences in modulatory effects of morphine on peritoneal inflammation in mice

Behavioural responsiveness to amphetamine or scopolamine following repeated exposure to chlorphenvinphos in rats

Diet- and fasting-induced changes of adrenal medulla activity and its influence on locomotor activity of rats

6-OHDA bilateral lesions to the central amygdala do not affect vasopressin improvement of recall in rats