Wyniki wyszukiwania

1

Chemical detoxification of carcinogenic heterocyclic aromatic amines by isothiocyanates

100%

Bartoszek A., Smiechowska A., Przychodzen W., Piekarska A., Namiesnik J.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

2

Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters

100%

Hayashi S., Nakamura E., Kubo Y., Takahashi N., Yamaguchi A., Matsui H., Hagen S. J., Takeuchi K.

Journal of Physiology and Pharmacology

|

2008

|

tom 59

|

nr 4

691-706

Isothiocyanate is a transient receptor potential ankyrin 1 (TRPA1) agonist and also an inhibitor of ion transporters such as anion exchanger (AE) and Na+/HCO3- co-transporter (NBC). We examined the expression of TRPA1 and ion transporters in monolayers of the rat gastric epithelial cell line RGM1 and investigated the involvement of these factors in the inhibitory action of isothiocyanate on epithelial wound healing. After obtaining a confluent monolayer, a round artificial wound of constant size was induced in the center of the cell monolayer using a pencil-type mixer with a rotating silicon tip. Immediately after the wound induction, cells at the edge of the wound started to form lamellipodia, migrating towards the center of wound, and the cell-free area decreased with time. Addition of allyl isothiocyanate to standard buffer suppressed the recovery of the wound in a concentration-dependent manner without affecting the viability of the RGM1 cells. Icilin, another TRPA1 agonist, dose-dependently inhibited wound repair. Likewise, 4,4’-diisothio- cyanatostilbene-2,2’-disulfonic acid (DIDS), a stilbene compound containing an isothiocyanate group, also inhibited the recovery of epithelial wounds. In addition, the repair of epithelial wounds was suppressed when the cells were incubated in Na+, Cl- or HCO3- free buffer. The RGM1 cells expressed the mRNAs of AE2a and NBC1 but not TRPA1. These results suggested that isothiocyanate impairs the repair of epithelial wounds in RGM1 cells, probably through the inhibition of ion transporters such as AE2a and NBC1 and not the activation of the TRPA1 channel. It is assumed that the process of epithelial repair is associated with the regulation of cell volume and intracellular pH (pHi) by these ion transporters.

3

Thermal degradation of sulphur containing aliphatic glucosinolates in broccoli sprouts

100%

Hanschen F. S., Platz S., Rohn S., Kroh L. W.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

4

Optimization of glucosinolate bioconversion into isothiocyanates using response surface methodology

100%

Alvarez Jubete L., Valverde J., Smyth T., Barry Ryan C.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

5

Reactions of isothiocyanates may affect flavour and colour of foods

84%

Cejpek K.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

6

The occurrence, role and contents of glucosinolates in Brassica vegetables

84%

Horbowicz M.

Vegetable Crops Research Bulletin

|

2003

|

tom 58

7

Hamowanie wzrostu Gaeumannomyces graminis var.tritici i Cephalosporium gramineum przez izotiocyjaniany

67%

Martyniuk S., Wroblewska B.

Progress in Plant Protection

|

1998

|

tom 38

|

nr 2

737-739

8

Quality of kohlrabi stems (Brassica oleracea var. gongylodes L.) kept in cold storage

67%

Gaweda M., Niziol-Lukaszewska Z.

Folia Horticulturae

|

2011

|

tom 23

|

nr 2

9

Biological activity of dietary glucosinolates and opportunities for their use in functional foods

67%

Mithen R.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

10

Food components targeting the epigenome

67%

Gerhauser C.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

11

Incorporation of inorganic selenium into seleno-glucosinolates in hairy root cultures of Nasturtium officinale R.Br.

67%

Wielanek M., Bergier K., Andrzejewska R., Sklodowska M.

Biological Letters

|

2005

|

tom 42

|

nr 2 Spec.Vol.

Ograniczanie wyników

Chemical detoxification of carcinogenic heterocyclic aromatic amines by isothiocyanates

Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters

Thermal degradation of sulphur containing aliphatic glucosinolates in broccoli sprouts

Optimization of glucosinolate bioconversion into isothiocyanates using response surface methodology

Reactions of isothiocyanates may affect flavour and colour of foods

The occurrence, role and contents of glucosinolates in Brassica vegetables

Hamowanie wzrostu Gaeumannomyces graminis var.tritici i Cephalosporium gramineum przez izotiocyjaniany

Quality of kohlrabi stems (Brassica oleracea var. gongylodes L.) kept in cold storage

Biological activity of dietary glucosinolates and opportunities for their use in functional foods

Food components targeting the epigenome

Incorporation of inorganic selenium into seleno-glucosinolates in hairy root cultures of Nasturtium officinale R.Br.