Wyniki wyszukiwania

1

Bioavailability of anthocyanins from red cabbage products

100%

Wiczkowski W., Topolska J., Szawara-Nowak D., Ornatowska A., Piskula M. K.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

|

nr Suppl.1

2

Homocysteine in atherogenesis

100%

Szostak W. B., Olszewski A. J.

Żywienie Człowieka i Metabolizm

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1990

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tom 17

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nr 4

Omówiono rolę homocysteiny w powstawaniu miażdżycy. Inni autorzy opisali zaawansowaną miażdżycę u pacjentów z homocystynurią. Wykazano także, że eksperymentalną miażdżycę można wywołać poprzez karmienie zwierząt homocysteiną i jej pochodnymi. Pirydoksyna jest istotnym składnikiem odżywczym odpowiedzialnym za przemianę homocysteiny do kwasu taurocholowego. Wykazano, że zbyt niskie spożycie pirydoksyny powoduje homocystynurię u ludzi i miażdżycę u zwierząt. Autorzy wykazali zwiększone stężenie homocysteiny w surowicy osób, które przebyły zawał mięśnia sercowego. Hipercholesterolemii towarzyszy szczególnie wysoki poziom homocysteiny we frakcji LDL. In vitro LDL modyfikowane tiolaktonem homocysteiny wykazują szczególne powinowactwo do makrofagów mysich. Pirydoksyna podana razem z niektórymi innymi witaminami powoduje u osób po zawale mięśnia sercowego znaczny spadek poziomu homocysteiny w surowicy. Autorzy wnioskują, że genetycznie uwarunkowane łagodne zaburzenia w metabolizmie homocysteiny mogą w pewnej części populacji przyczyniać się do rozwoju przedwczesnej miażdżycy w przypadku, kiedy dieta jest bogata w metioninę i niedoborowa w pirydoksynę.

3

Effects of physical activity on carbohydrate and lipid metabolism in women with abdominal obesity

84%

Kasprzak Z., Pilaczynska-Szczesniak L.

Trends in Sport Sciences

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2013

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tom 20

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nr 3

Introduction. The incidence of metabolic disorders in obese people is not only determined by the amount of adipose tissue but mainly by its distribution. Metabolic disorders may lead to the development of occupational metabolic diseases. Aim of Study. The aim of the study was to estimate the effects of increased physical activity in women with abdominal obesity on carbohydrate and lipid metabolism and glucose tolerance. Material and Methods. The study was carried out on a group of 32 physically active women aged 59.1 ± 5.39 years. Somatic traits were measured and physiological and biochemical tests (VO2 max, lipid profile, glucose and insulin levels) were carried out at rest while fasting. The BMI, WHR and HOMAIR indices were calculated. Results. The following results were obtained for the sample: BMI (32.9 ± 4.57 kg/m²), WHR (0.88 ± 0.04), VO₂ max (33.6 ± 8.19 ml/kg⁻¹/min⁻¹), total cholesterol (226.3 ± 45.12 mg/dl), LDL-cholesterol (140.6 ± 37.79 mg/dl). Conclusions. The results confirm positive effects of physical activity on the lipid profile and the homeostatic model assessment insulin resistance index (HOMAIR).

4

Rola boru w przemianach metabolicznych i w zywieniu czlowieka

84%

Biernat J., Pieczynska J.

Bromatologia i Chemia Toksykologiczna

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2000

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tom 33

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nr 4

289-294

5

A focus on homocysteine in autism

84%

Kaluzna-Czaplinska J., Zurawicz E., Michalska M., Rynkowski J.

Acta Biochimica Polonica

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2013

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tom 60

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nr 2

Homocysteine is an amino acid, which plays several important roles in human physiology. A wide range of disorders, including neuropsychiatric disorders and autism, are associated with increased homocysteine levels in biological fluids. Various B vitamins: B6 (pyridoxine), B12 (cobalamin), and B9 (folic acid) are required as co-factors by the enzymes involved in homocysteine metabolism. Therefore, monitoring of homocysteine levels in body fluids of autistic children can provide information on genetic and physiological diseases, improper lifestyle (including dietary habits), as well as a variety of pathological conditions. This review presents information on homocysteine metabolism, determination of homocysteine in biological fluids, and shows abnormalities in the levels of homocysteine in the body fluids of autistic children.

6

Zastosowanie chromatografii kolumnowej na zywicy Toyopearl WH-40S przy oczyszczaniu standardu werbaskozy

67%

Karamac M., Amarowicz R.

Bromatologia i Chemia Toksykologiczna

|

2002

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tom 35

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nr 4

403-406

7

Wplyw fluorkow na metabolizm komorek tkanki lacznej

67%

Olszowski T., Chlubek D.

Bromatologia i Chemia Toksykologiczna

|

2002

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tom 35

|

nr 1

27-30

8

Rola chromu w zywieniu czlowieka

67%

Sobanski L., Sprzeczka-Niedolaz M., Lebek G.

Bromatologia i Chemia Toksykologiczna

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2007

|

tom 40

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nr 2

113-119

9

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Procesy biochemiczne i mechanizmy molekularne toksycznosci glinu

67%

Graczyk A., Dlugaszek M.

Roczniki Państwowego Zakładu Higieny

|

1993

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tom 44

|

nr 1

23-42

Na podstawie literatury omówiono metabolizm glinu, lokalizację tego pierwiastka w komórkach i tkankach ludzkich i zwierzęcych oraz zachowanie jonów glinu na poziomie struktur komórkowych.

10

Effect of phytoestrogen intake in the diet on lipid and sex hormone metabolism in menopausal women, and increased risk of breast cancer

67%

Kostrzewa-Tarnowska A., Czlapka-Matyasik M., Walkowiak J., Godlewski D.

Journal of Pre-Clinical and Clinical Research

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2015

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tom 09

|

nr 2

Introduction and objective. Phytoestrogens are one of nutritional factors exhibiting a chemoprotective action, potentially reducing vasomotor symptoms as well as cancerous lesions. The study was ocused on an association between the consumption of phytoestrogens in the diet, blood serum cholesterol concentration and urinary estrogen metabolites levels. Materials and methods. The study was conducted on 55 women in the perimenopausal period, who were characterized by an increased risk of hormone-dependent cancer. Energy and nutritive value of food rations, and especially the level of phytoestrogen consumption in the diets in the examined population, were analyzed using the Wikt Pro computer programme. Estrogen metabolites (2OHE, 16α-OHE1) were determined from 24‑urine samples by the ELISA method. The EMR index was calculated. Plasma total cholesterol concentrations was measured. Results and conclusions. The population with a higher consumption of phytoestrogens and dietary fibre in the diet, at the simultaneous slight limitation of energy value of the food ration, is characterized by an improved blood serum cholesterol concentration and an appropriate estrogen metabolism towards a significant increase in the estrogen index for the cancer lesions in the mammary glands.

11

Nienasycone kwasy tluszczowe z rodziny Omega-3. Cz.I. Struktura, zrodla, oznaczanie, przemiany w organizmie

67%

Bartnikowska E., Obiedzinski M. W.

Roczniki Państwowego Zakładu Higieny

|

1997

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tom 48

|

nr 4

381-397

Podano strukturę, źródła, oznaczanie oraz przemiany wielonienasyconych kwasów tłuszczowych (PUFA, n-3) zachodzące w organizmie

12

Porfirynuria w przewleklych chorobach watroby

67%

Goljan J.

Acta Biologica et Medica

|

1992

|

tom 19

103-114

13

Metabolic disorders in women at procreative age living in Warsaw

67%

Szostak-Wegierek D., Waskiewicz A.

Roczniki Państwowego Zakładu Higieny

|

2015

|

tom 66

|

nr 3

Background. Abnormal body mass and related metabolic disorders may affect female reproductive health. Objectives. To determine the prevalence of under- and overweight, and also related metabolic disorders, among women at procreative age in Warsaw. Materials and Methods. 164 non-pregnant women at procreative age (20-49 years) living in Warsaw, who in 2011-2012 participated in the WAW-KARD cross-sectional study of the Warsaw population, assigned to 3 age groups: 20-29 years (n=17), 30-39 years (n=78) and 40-49 years (n=69). Results. Under- and overweight, obesity and abdominal obesity was found in respectively 1.2%, 25%, 12.2% and 37.2% of the participants. Prevalence of excessive body mass tended to increase with age. Hypercholesterolemia was shown in 42.7% of the whole group and was particularly widespread in the oldest females (56.5%). Prevalence of low serum HDL-cholesterol levels (found in 13.4% of the whole group) tended to increase with age, on the borderline of statistical significance. The mean fasting glucose level was 5.0 ± 0.4 mmol/l and tended to increase with age. Impaired fasting glucose concerned 7.7% and 10.6% of females in age groups of 30-39 and 40-49 years respectively, and diabetes 4.4% of females 40-49 years old. Prevalence of arterial hypertension and metabolic syndrome (MS) in the whole group was 10.4% and 7.3% respectively; prevalence of MS tended to increase with age, on the borderline of statistical significance. Conclusions. Overweight and obesity, especially of abdominal type, are prevalent in women at procreative age in Warsaw. Disturbances of lipid and glucose metabolism, as well as arterial hypertension and MS, are also frequent. Prevalence of many of them tended to increase with age. Some of the women exhibited diabetes.

14

Zywnosc i napoje dla sportowcow

67%

Kolanowski W., Jedrzejczyk H.

Żywność, Żywienie a Zdrowie

|

1999

|

tom 08

|

nr 4

410-416

15

Magnesium: its role in nutrition and carcinogenesis

67%

Blaszczyk U., Duda-Chodak A.

Roczniki Państwowego Zakładu Higieny

|

2013

|

tom 64

|

nr 3

Magnesium (Mg2+) plays a key role in many essential cellular processes such as intermediary metabolism, DNA replication and repair, transporting potassium and calcium ions, cell proliferation together with signalling transduction. Dietary sources rich in magnesium are whole and unrefined grains, seeds, cocoa, nuts, almonds and green leafy vegetables. Hard water is also considered to be an important source of magnesium beneficial to human health. The daily dietary intake of magnesium is however frequently found to be below that recommended in Western countries. Indeed, it is recognised that magnesium deficiency may lead to many disorders of the human body, where for instance magnesium depletion is believed to play an important role in the aetiology of the following; cardiovascular disease (including thrombosis, atherosclerosis, ishaemic heart disease, myocardial infarction, hypertension, arrhythmias and congestive heart failure in human), as well as diabetes mellitus, gastrointestinal (GI) tract disease, liver cirrhosis and diseases of the thyroid and parathyroid glands. Insufficient dietary intake of magnesium may also significantly affect the development and exacerbation of ADHD (Attention Deficit- Hyperactivity Disorder) symptoms in children. The known links between magnesium and carcinogenesis still remain unclear and complex, with conflicting results being reported from many experimental, epidemiological and clinical studies; further knowledge is thus required. Mg2+ ions are enzyme cofactors involved in DNA repair mechanisms that maintain genomic stability and fidelity. Any magnesium deficiencies could thereby cause a dysfunction of these systems to occur leading to DNA mutations. Magnesium deficiency may also be associated with inflammation and increased levels of free radicals where both inflammatory mediators and free radicals so arising could cause oxidative DNA damage and therefore tumour formation. The presented review article now provides a summary discussion of the various research performed concerning the impact that low magnesium intake has on tumour incidence; this includes impairment of magnesium homeostasis frequently observed in tumour cells, the influence of magnesium depletion on the progression of existing tumours and the occurrence of hypo-magnesaemia when patients are treated with certain anticancer drugs.

16

Aktywnosc enzymow bioracych udzial w metabolizmie amin katecholowych u kobiet narazonych na przewlekle dzialanie dwusiarczku wegla

67%

Stanosz S., Kuligowski D., Kuligowska E.

Bromatologia i Chemia Toksykologiczna

|

1994

|

tom 27

|

nr 3

265-268

U 90 kobiet , z prawidłowymi cyklami miesięcznymi, oznaczono aktywność DBH w surowicy, COMT w erytrocytach oraz MAO w surowicy i w płytkach krwi. Stwierdzono, że u kobiet narażonych na przewlekłe działanie CS2 występuje znamienne obniżenie aktywności wszystkich badanych enzymów biorących udział w metabolizmie amin katecholowych.

17

Metabolizm nikotyny

67%

Tyrpien K.

Bromatologia i Chemia Toksykologiczna

|

2002

|

tom 35

|

nr 1

17-25

18

Stezenie ferrytyny w surowicy krwi pracownikow narazonych na dzialanie manganu

67%

Misiewicz A., Jelen B., Radwan K., Gonciarz R.

Bromatologia i Chemia Toksykologiczna

|

1994

|

tom 27

|

nr 3

207-210

W porównaniu z grupą kontrolną u pracowników narażonych na działanie manganu stwierdzono: nie zmienione stężenie ferrytyny w surowicy krwi, zwiększoną liczbę krwinek czerwonych w mm3 krwi obwodowej przy równoczesnym zwiększeniu wartości hematokrytowej, zmniejszenie średniej masy hemoglobiny z tendencją do zmniejszenia średniego stężenia hemoglobiny w przeciętnej krwince czerwonej bez zmian objętości krwinek czerwonych.

19

Wplyw fitoestrogenow pokarmowych na organizm czlowieka. Cz.I. Wystepowanie fitoestrogenow w zywnosci oraz ich metabolizm

67%

Prescha A., Biernat J.

Bromatologia i Chemia Toksykologiczna

|

2008

|

tom 41

|

nr 3

209-214

20

The origin and metabolism of a nascent pre-beta high density lipoprotein involved in cellular cholesterol efflux

67%

Wroblewska M.

Acta Biochimica Polonica

|

2011

|

tom 58

|

nr 3

The pre-β HDL fraction constitutes a heterogeneous population of discoid nascent HDL particles. They transport from 1 to 25 % of total human plasma apo A-I. Pre-β HDL particles are generated de novo by interaction between ABCA1 transporters and monomolecular lipid-free apo A-I. Most probably, the binding of apo A-I to ABCA1 initiates the generation of the phospholipid-apo A-I complex which induces free cholesterol efflux. The lipid-poor nascent pre-β HDL particle associates with more lipids through exposure to the ABCG1 transporter and apo M. The maturation of pre-β HDL into the spherical α-HDL containing apo A-I is mediated by LCAT, which esterifies free cholesterol and thereby forms a hydrophobic core of the lipoprotein particle. LCAT is also a key factor in promoting the formation of the HDL particle containing apo A-I and apo A-II by fusion of the spherical α-HDL containing apo A-I and the nascent discoid HDL containing apo A-II. The plasma remodelling of mature HDL particles by lipid transfer proteins and hepatic lipase causes the dissociation of lipid-free/lipid-poor apo A-I, which can either interact with ABCA1 transporters and be incorporated back into pre-existing HDL particles, or eventually be catabolized in the kidney. The formation of pre-β HDL and the cycling of apo A-I between the pre-β and α-HDL particles are thought to be crucial mechanisms of reverse cholesterol transport and the expression of ABCA1 in macrophages may play a main role in the protection against atherosclerosis.

Ograniczanie wyników

Bioavailability of anthocyanins from red cabbage products

Homocysteine in atherogenesis

Effects of physical activity on carbohydrate and lipid metabolism in women with abdominal obesity

Rola boru w przemianach metabolicznych i w zywieniu czlowieka

A focus on homocysteine in autism

Zastosowanie chromatografii kolumnowej na zywicy Toyopearl WH-40S przy oczyszczaniu standardu werbaskozy

Wplyw fluorkow na metabolizm komorek tkanki lacznej

Rola chromu w zywieniu czlowieka

Procesy biochemiczne i mechanizmy molekularne toksycznosci glinu

Effect of phytoestrogen intake in the diet on lipid and sex hormone metabolism in menopausal women, and increased risk of breast cancer

Nienasycone kwasy tluszczowe z rodziny Omega-3. Cz.I. Struktura, zrodla, oznaczanie, przemiany w organizmie

Porfirynuria w przewleklych chorobach watroby

Metabolic disorders in women at procreative age living in Warsaw