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Prevalence of human papillomavirus [HPV] and herpes simplex virus type 2 [HSV-2] in cervical dysplasias and carcinomas

100%

Pochylski T., Kwasniewska A.

Bulletin of the Veterinary Institute in Puławy. Supplement

2002

Fold recognition insights into function of herpes ICP4 protein

84%

Wyrwicz L. S., Rychlewski L.

Acta Biochimica Polonica

2007

tom 54

nr 3

ICP4 is an important factor regulating the life cycle of HSV1. This conserved protein has several molecular functions, including activation of expression of viral late gene transcripts and inhibition of immediate early genes. Although ICP4 and its Alphaherpesvirinae homologs (eg.: IE62 of VZV) have been subjects of various molecular studies, a complete view of their molecular function is lacking. Here we present the results of fold recognition and molecular modelling of ICP4 functional domains. The performed state-of-the-art bioinformatic fold recognition analysis identified a dual helix-turn-helix motif as a binding module of repressor activities (so called region 2 domain). The mapping of distant homology identified that a segment responsible for activation of late gene promoters (region 4) exhibits folding of uracil DNA glycosylase (UDG), but seems to be a non-functional homolog of UDG. Potential implications of the results are discussed.

Inhibition of herpes simplex virus type 2 by vaginal lactobacilli

67%

Conti C., Malacrino C., Mastromarino P.

Journal of Physiology and Pharmacology. Supplement

2009

tom 60

nr 6

Disseminated adenovirus disease in immunocompromised patient successfully treated with oral ribavirin: a case report

67%

Ulrych E. E., Dzieciatkowski T., Przybylski M., Zdunczyk D., Boguradzki P., Torosian T., Waszczuk-Gajda A., Rynans S., Wroblewska M., Jedrzejczak W. W., Mlynarczyk G.

Archivum Immunologiae et Therapiae Experimentalis

2011

tom 59

nr 6

Gender specific differences in the immune response to infection

59%

McClelland E. E., Smith J. M.

Archivum Immunologiae et Therapiae Experimentalis

2011

tom 59

nr 3

Ograniczanie wyników

2 Archivum Immunologiae et Therapiae Experimentalis

1 Acta Biochimica Polonica

1 Bulletin of the Veterinary Institute in Puławy. Supplement

1 Journal of Physiology and Pharmacology. Supplement

1 Boguradzki P.

1 Conti C.

1 Dzieciatkowski T.

1 Jedrzejczak W. W.

1 Kwasniewska A.

1 Malacrino C.

1 Mastromarino P.

1 McClelland E. E.

1 Mlynarczyk G.

1 Pochylski T.

1 Przybylski M.

1 Rychlewski L.

1 Rynans S.

1 Smith J. M.

1 Torosian T.

1 Ulrych E. E.

1 Waszczuk-Gajda A.

1 Wroblewska M.

1 Wyrwicz L. S.

1 Zdunczyk D.

2 2011

1 2009