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In the article the authors consider the functioning of small farms. The paper focuses on crucial problems connected with the defi nition of small farms and with their traditional and modern functions. The paper presents farmers’ opinions about small agricultural operations, as information was collected from 100 farmers from Kozienicki county, Poland. The farmers had from 1 to 5 ha of agricultural land. Respondents’ declarations indicate that small farms perform mainly social functions. They expressed their definition of a small farm as one having from 1 to 10 ha of agricultural land. The majority of respondents were dissatisfi ed with their agriculture income. Their main reason for continuing activity in agriculture was the fact that they were the only successors in the family.
The diet is directly connected not only with the physical status but also with the functioning of the brain and the mental status. The potentially beneficial nutrients with a protective effect on the nervous system function include amino acids (tryptophan, phenylalanine, tyrosine, taurine), glucose and vitamins C, E, D and beta-carotene, B group vitamins (vitamin B12, vitamin B6, vitamin B4, vitamin B1) and minerals (selenium, zinc, magnesium, sodium, iron, copper, manganese, iodine). The presence of antioxidants in the diet protects against oxidative damage to nervous system cells. Biochemical data indicate that polyunsaturated fatty acids such as arachidonic acid (AA), docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) as structural components of the nervous system play a key role in its function. The nutrition of the entire body also influences the production of neurotransmitters in the brain. A diet without an appropriate supply of protein, mineral nutrients or vitamins may result in a failure to form appropriately balanced numbers of neurotransmitters, which, as a result, may lead to neurotransmission dysfunction. This is the reason why proper nutrition is based on vegetables, fruits, whole-grain cereal products supplemented with products providing full-value protein (dairy products, fish, lean meat) and high-quality fat products (vegetable oils, fish fats).
Neurological diseases, including intellectual disability (ID), can be caused by disturbances in epigenetic regulation of specific genes that encode proteins necessary for appropriate central nervous system functioning. The “epigenetically caused” diseases can be due to the imprinting defects formed during germinal cells development or gained throughout life as a somatic changes. They can also result from abnormal functioning of transcriptional machinery caused by mutations in genes coding for specific proteins. Two most classical examples of disease caused by imprinting defect in germinal cells are Prader-Willi and Angelman syndromes, both characterized by ID and developmental delay. Both these diseases are caused by altered epigenetic regulation of genes localized on chromosome 15 (region q11–q13) that can be due to chromosome deletion or uniparental disomy. The other neurological disease that is related to abnormal epigenetic regulation is Fragile X syndrome characterized by ID and specific behavior. Almost all disease cases are due to the expansion of CGG repeat (>200) in the 5’UTR of FMR1 gene that leads to promoter methylation and lack of FMRP protein that is indispensable for neuron development and signaling. The example of neurological “epigenetic diseases” caused by altered transcriptional regulation is Rett syndrome caused by the mutation presence in MECP2 gene or its variant – Rett-like syndrome caused by the mutation in CDKL5 gene. Both these diseases are characterized by ID and childhood epilepsy. Herein, we present our experience from the research and diagnosis of above mentioned disorders in the context of neurological pathways altered by improper epigenetic regulation.
Changes in perception of the rural areas from the perspective of agriculture only gave the impulse for emergence of a new direction in the Common Agricultural Policy (CAP) of the European Union (EU). The Leader initiative established in 1991 aims at activating rural communities and rational local resources management. Local action groups (LAG) that assume the form of agreements of three local sectors (representatives of community, entrepreneurs and representatives of authorities) are the units implementing the Leader approach. The questionnaire based survey covering 44% of the LAGs operating in Poland was conducted. Thanks to that survey knowledge of the specificity and outcomes of their work was obtained.
Our paper presents natural environment functions in a systemic approach. Its main principle is to consider a problem as a whole and to perceive reality in the same way. This approach is implicated by the crisis of reductionism in explaining natural, social and economical processes and phenomena, as well as by still rising and intensifying consequences of human interference in the environment. The synthesis of ecology rules and the most important features of complex dynamic systems implicate the statement that balance in the environment is a special state rather than a destination state because natural systems undergo continuous evolutional changes. The existence of feedback makes the changes either run gently and die out or take a catastrophic course and leave the control of societies interfering in the environment. The systemic approach to natural enviroment functioning presented in this paper suggests taking care in its economical application and forming. In theoretical consideration it has been pointed out how economical societies should shape their relations with the environment so that they become the basis for sustainable development.
The main question in this review is of whether and how the cytoskeleton of guard cells is involved in stomata movements. The main function of stomata is the regulation of the rate of gas exchange between the plant environment and underlying plant tissues. As a result of special morphology and anatomy GCs form the stomatal pore. It can open or close in a controlled manner via internal or external signal-induced changes in GCs turgor pressure, volume and shape. The mechanism of stomata movement is a complex process. A network of actin microfilaments and microtubules, dynamic polymers collectively known as the cytoskeleton forms protein fibril systems in GCs. CT elements are dynamic structures, interconnected to different cell structures. The organization of CT during morphogenesis of stomata is very important in establishing the size and shape of GCs. It is well documented that AFs and MTs are involved in stomata movements and can modify the ability of GCs to respond to environmental and hormonal stimuli. Data gathered clearly suggest that the organization of CT elements is not a direct effect of stomata movements. Several investigation procedures for study of the CT role in stomata functioning, including GCs treatment with anti-CT drugs (disrupters or stabilizers), have been analyzed and discussed in this review but the question of what role AFs and MTs play in stomata movements and how they work still remains open. The availability of new CT visualization techniques and the usage of mutants to study this problem is a good perspective for further research.
The species richness pattern exhibits a strong altitudinal dependence which may be altered under the influence of land use-related disturbances. The Beskid Niski Mountains are part of the northern Carpathian Mountains – an area that saw a large-scale relocation of certain ethnic groups after World War II. The subsequent rapid decline in the human population level was the main factor shaping the environment in this area, and contributed to a rapid increase in the forest area, also introducing changes in its functioning. The increase in the forest area was not evenly distributed, showing the largest values at higher locations. The present study is focused on changes in the species richness of the Carpathian fir forests along the altitudinal gradient, in relation to socio-economical transformations. The changes indicated an overall decrease in species richness, especially at higher locations. The main reason for these changes seemed to be forest management-related, causing an increase in the share of blackberry, fern and grass species, as well as the disappearance of species diagnostic of the ancient forests, which led to homogenization of vegetation. The increase in the mountain forest area has proven to be insufficient to secure the species richness of forests.
At present, there is a great emphasis of public opinion on the legalisation of medical marijuana, i.e. the top parts of the cannabis plants rich in tetrahydrocannabinol (THC). Nevertheless, in the cannabis plants, there are many various cannabinoids, including cannabidiol (CBD). Scientific reports to-date indicate the possibility for using pharmacologically active cannabinoids in the treatment of such diseases/symptoms as: anorexia, vomiting, neuropathic pain, inflammatory diseases, multiple sclerosis, degenerative diseases of the central nervous system (Parkinson’s disease, Huntington’s disease, Alzheimer’s disease, Tourette’s syndrome), epilepsy, schizophrenia, and obesity. The article presents up-to-date information on the results of experimental studies concerning the effectiveness of cannabinoids, with particular consideration of diseases related with the central nervous system, including epilepsy, neuropathic pain, mental disorders, as well as obesity and anorexia.
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