Wyniki wyszukiwania

1

The biotransformation of chosen mycotoxins

100%

Gajecka M., Jakimiuk E., Zielonka L., Obremski K., Gajecki M.

Polish Journal of Veterinary Sciences

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2009

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tom 12

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nr 2

293-303

Despite the unfavourable influence of mycotoxins on human and animal health and few toxi- cological aspects that have been documented, about these biologically active substances has not been explored. Aiming at more knowledge and a better understanding of the effects and mechanism of mycotoxin action in mammals would provide the basics for developing strategies to restrain different mycotoxicoses. One of the processes not fully understood is biotransformation, to which mycotoxins are subjected the animal organism. Biotransformation is the conversion of mycotoxins to non-toxic metabolites and occurs mostly in the intestinal mucosal membrane and liver, although other tissues and systems also take part in this process. Mycotoxin biotransformation reactions can be considered bioinactivation or detoxication, but mycotoxin biotransformation processes could also result in products more toxic than the mycotoxin. It can be concluded from research studies that our knowledge of mycotoxin biotransformation is scarce.

2

Mycotoxins and mycotoxicoses under climatic conditions of Poland

80%

Golinski P., Waskiewicz A., Gromadzka K.

Polish Journal of Veterinary Sciences

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2009

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tom 12

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nr 4

Ochratoxin A (OA), zearalenone (ZON), moniliformin (MON) as well as trichotecenes and fumonisines (FUM) are naturally occurring contaminants of cereals and animal feed. They pose a health risk not only to humans but also to livestock and, as a consequence, may cause economical losses either due to unfavorable effects on domestic animals themselves or to an increased potential for health effects in human beings consuming mycotoxin-contaminated edible animal products. At present, large-scale studies are carried out in EU countries to determine a safe, admissible concentration of these toxins in cereals and their processed products. The aim of this review is to collect and summarize information concerning the properties, occurrence and toxicity of these mycotoxins.

3

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Incidence of fumonisins, moniliformin and Fusarium species in poultry feed mixtures from Slovakia

80%

Labuda R., Parich A., Vekiru E., Tancinova D.

Annals of Agricultural and Environmental Medicine

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2005

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tom 12

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nr 1

A total of 50 samples of poultry feed mixtures of Slovak origin were analysed for fumonisin B1 and B2 (FB1, FB2) and moniliformin (MON) using SAX-clean up procedure being detected by high pressure liquid chromatography with mass spectrometry (HPLC-MS) and diode array detection (HPLC-DAD), respectively. The samples were also simultaneously investigated for Fusarium species occurrence, and for the capability of Fusarium isolates recovered to produce FB1 and MON in vitro. FB1 was detected in 49 samples (98%) in concentrations ranging from 43 to 798 µg.kg-1, and FB2 in 42 samples (84%) in concentrations ranging from 26 to 362 µg.kg-1. MON was detected in 26 samples (52%) in concentrations that ranged from 42 to 1,214 µg.kg-1. Only two Fusarium populations were encountered, namely F. proliferatum and F. subglutinans, of which the former was the most dominant and frequent. All 86 F. proliferatum isolates tested for FB1-production ability proved to be producers of the toxin although none of them produced MON. On the contrary, MON production was observed in a half out of 16 F. subglutinans isolates tested, yet no FB1 production was detected in this case. Despite the limited number of samples investigated during this study, it is obvious that poultry feed mixtures may represent a risk from a toxicological point of view and should be regarded as a potential source of the Fusarium mycotoxins in central Europe. This is the first reported study dealing with fumonisin and moniliformin contamination of poultry feeds from Slovakia.

4

Występowanie fumonizyny w ziarniakach i rdzeniach kolb kukurydzy inokulowanych Fusarium verticillioides

71%

Wit M., Waskiewicz A., Golinski P., Chelkowski J., Warzecha R., Ochodzki P., Wakulinski W.

Progress in Plant Protection

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2010

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tom 50

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nr 4

Biosyntesis of fumonisin FB1, ergosterol content in kernels and rachis of artificially infected maize cobs was studied. The experiment was arranged in three factorial design (variety, strain, harvest time). Performed analysis revealed significant differences in fumonisin FB1 level depending on collection time. The level of mycotoxin was highly correlated with infection degree as well as with ergosterol content.

5

Contamination of herbal drugs in regulations and future devlopments

70%

Kabelitz L.

Herba Polonica

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2003

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tom 49

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nr 1-2

6

The influence of mycotoxins exposure on human and animal health

61%

Sztanke K., Pasternak K., Kulik T.

Polish Journal of Environmental Studies

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2004

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tom 13

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nr Suppl.2, Part 1

Mycotoxins are the secondary fungal metabolites, which cause toxic effects on human and animal organisms. They are frequent food contaminants. The most common route of exposure to mycotoxins is ingestion, but it may also involve dermal, respiratory and parenteral routes. These metabolites are produced by various fungal and mould strains like Aspergillus spp., Penicillium spp. and Fusarium spp. The most prominent mycotoxins are aflatoxins, trichothecenes, zearalenone, ochratoxins, fumonisins, patulin, citrinin, alternariol and its monomethyl ether, gliotoxin and beauvericin. There are several diseases, which are mycotoxin-related. Mycotoxins cause acute and chronic intoxications (mycotoxicoses), allergies and tumours. They may demonstrate genotoxic, mutagenic, cytotoxic, teratogenic and carcinogenic properties. Some of them cause strong estrogenic effects and infertility. The others are immunosuppressive, nephrotoxic and hepatotoxic. Taking into account wide range of mycotoxins toxic effects on living organisms, it is established that these compounds are the one of main factors influencing human and animal health.

7

Immunosupresja - nieinfekcyjne przyczyny niskiej efektywności w produkcji świń

61%

Porowski M., Porowski M., Porowski S., Porowski M.

Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii

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2018

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tom 13

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nr 4

8

Mikotoksyny w zywnosci jako czynnik zagrozenia zdrowotnego

61%

Czerwiecki L.

Żywność, Żywienie a Zdrowie

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1997

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tom 06

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nr 4

292-300

9

Oznaczanie wybranych mikotoksyn w zywnosci. Cz.II. Dobor optymalnych warunkow oznaczania fumonizyn B1 i B2 w przetworach z kukurydzy metoda wysokosprawnej chromatografii cieczowej

61%

Czerwiecki L.

Roczniki Państwowego Zakładu Higieny

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1998

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tom 49

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nr 1

13-24

Opisano optymalne warunki oznaczania fumonizyn B1 і В2 w przetworach z kukurydzy. Zbadano przebieg procesu ekstrakcji, oczyszczania ekstraktów, tworzenia fluoryzujących pochodnych fumonizyn oraz wysokosprawnej chromatografii cieczowej. Średni odzysk metody w zależności od poziomu fortyfikacji oraz rodzaju badanej próbki wynosił 64-95%, granica wykrywalności 15 µg każdej z fumonizyn w kilogramie produktu.

Ograniczanie wyników

The biotransformation of chosen mycotoxins

Mycotoxins and mycotoxicoses under climatic conditions of Poland

Incidence of fumonisins, moniliformin and Fusarium species in poultry feed mixtures from Slovakia

Występowanie fumonizyny w ziarniakach i rdzeniach kolb kukurydzy inokulowanych Fusarium verticillioides

Contamination of herbal drugs in regulations and future devlopments

The influence of mycotoxins exposure on human and animal health

Immunosupresja - nieinfekcyjne przyczyny niskiej efektywności w produkcji świń

Mikotoksyny w zywnosci jako czynnik zagrozenia zdrowotnego

Oznaczanie wybranych mikotoksyn w zywnosci. Cz.II. Dobor optymalnych warunkow oznaczania fumonizyn B1 i B2 w przetworach z kukurydzy metoda wysokosprawnej chromatografii cieczowej