Wyniki wyszukiwania

1

The eradication of enzootic bovine leucosis in a large farm population

100%

Deren W., Szewczyk-Sadowska A., Rulka J.

Polish Journal of Veterinary Sciences

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2003

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tom 06

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nr 3 Suppl.

2

Guidelines in the medical treatment of Helicobacter pylori infection

100%

Dzieniszewski J., Jarosz M.

Journal of Physiology and Pharmacology. Supplement

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2006

|

tom 57

|

nr 3

143-154

Scientific evidence based on controlled clinical research confirm substantial benefits resulting from the eradication of H. pylori infection in such pathologies of the alimentary tract as: gastric peptic and duodenal ulcer (active or confirmed in the future and ulcer disease complications), MALT (Mucosa Associated Limphoid Tissue) lymphoma, atrophic gastritis, past stomach resection, gastric cancer in the family. The above group of indications is strongly recommended for eradicative treatment. During the last several years there have been many guidelines made by international and national specialist groups. “Test and treat” strategy of undiagnosed dyspepsia treatment is based on possibility to carry out non-invasive tests confirming H. pylori infection. First symptoms of dyspepsia in people over 45 years of age constitute recommendation for endoscopy, as well as symptoms assumed to be “alarming” (loss of weight, anaemia, bloody vomiting, tarry stool, dysphagia) regardless of patient age. An individual approach to eradication is proposed in gastroesophageal reflux disease, and use of non-steroid anti-inflammatory drugs. Antibacterial activity towards H. pylori is shown by many antibiotics (amoxicillin, macrolides, tetracyclines) and some other chemotherapeutic agents (nitroimidazoles) and bismuth. PPIs are recommended, because through increase of pH in stomach they create conditions to act for antibiotics. During the stage of first line triple therapy, it is advised to apply PPI and two antibacterial medicines at the same time (PPI + amoxicillin+metronidazole or clarithromycin). Such therapeutic action ensures achievement of eradication of H. pylori infection in 80-90% of cases. In case of lack of treatment efficiency in the first-line therapy, 7-14 day treatment may be repeated using triple therapies (PPI + 2 antibiotics) substituting the antibiotic with the metronidazole or tetracycline, or quadruple therapies (PPI + bismuth citrate + 2 antibiotics). Side effects during eradicative treatments occur quite rarely (from 15 to 30%).

3

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Eradication of scabies on a swine farm with the use of the preparation invermectin 1 percentage [Biowet Gorzow]

100%

Pacon J., Rypula K., Bulzacki K.

Wiadomości Parazytologiczne

|

1998

|

tom 44

|

nr 3

4

Helicobacter pylori eradication and antral intestinal metaplasia - two years follow-up study

100%

Ciok J., Dzieniszewski J., Lucer C.

Journal of Physiology and Pharmacology. Supplement

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1997

|

tom 48

|

nr 4

5

The influence of cholecystokinin on gastric myoelectrical activity in duodenal ulcer following Helicobacter pylori eradication - an electrogastrographic study

100%

Budzynski A., Dobrzynski A., Lorens K., Konturek P. C., Thor P., Konturek S. J.

Journal of Physiology and Pharmacology

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2002

|

tom 53

|

nr 2

Cholecystokinin (CCK) plays an important role in the regulation of postprandial gastric motor activity which was found to be abnormal in duodenal ulcer patients. This study was designed to compare the influence of CCK on gastric myoelectrical function in duodenal ulcer patients and healthy controls. Fifteen patients with active duodenal ulcer and Helicobacter pylori (H. pylori) infection and 15 healthy controls were included into this study. Electrogastrography (EGG) was performed before and 4 weeks after the eradication of H. pylori in ulcer patients and in healthy controls. We compared EGG parameters in the fasting and postprandial period and during intravenous infusion of caerulein, an analog of CCK with or without addition of loxiglumide, a specific CCK-1 receptor antagonist. The amplitude of fasting EGG in duodenal ulcer patients was similar to that in control subjects and was not affected by H. pylori eradication. In contrast, the amplitude of postprandial EGG was markedly increased in duodenal ulcer patients when compared to that in healthy controls and it was significantly reduced following the eradication of H. pylori. The blockade of CCK-1 receptors with loxiglumide in healthy controls or H. pylori eradicated ulcer patients significantly enhanced postprandial EGG amplitude almost to the level observed in the infected duodenal ulcer patients, but failed to affect this amplitude in ulcer patients. Exogenous caerulein, an analog of CCK, failed to affect EGG amplitude in duodenal ulcer patients with H. pylori infection, but it reduced significantly EGG amplitude in these patients after H. pylori eradication and in control subjects. This inhibitory effect of caerulein in H. pylori negative ulcer patients and healthy controls was abolished by the addition of loxiglumide. Ulcer patients showed significant dysrhythmia with tachygastria up to 20% of the recording time both under basal conditions and postprandially and H. pylori eradication was followed by a significant decrease in tachygastria to about 5%, the value being similar to that in healthy controls. We conclude that the amplitude and frequency of gastric myoelectrical activity are enhanced in duodenal ulcer patients and impaired in response to CCK but these changes can be normalized by successful H. pylori eradication.

6

Ranitidine bismuth citrate plus clarithromycin for the eradication of H.pylori

100%

Dixon J. S., Pipkin G. A., Mills J. G., Wood J. R.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 4

7

Helicobacter pylori eradication: direct costs implication in gastric duodenal diseases

100%

Deltenre M.

Journal of Physiology and Pharmacology. Supplement

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1997

|

tom 48

|

nr 1

8

The sterile insect technique as a component of sustainable area-wide integrated pest management of selected horticultural insect pests

100%

Vreysen M. J. B., Hendrichs J., Enkerlin W. R.

Journal of Fruit and Ornamental Plant Research

|

2006

|

tom 14

|

nr Suppl.3

9

Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children

84%

Kotlowska-Kmiec A., Bakowska A., Szarszewski A., Kaminska B., Luczak G., Radys W., Landowski P., Brodzicki J., Korzon M., Liberek A.

Acta Biochimica Polonica

|

2009

|

tom 56

|

nr 3

433-438

The pathomechanism of Helicobacter pylori action upon gastric mucosa and its role in the pathogenesis of gastritis have not been fully elucidated. The aim of this study was to evaluate the most prevalent lymphocyte subpopulations of the gastric mucosa in gastritis in children, as well as to evaluate the expression of Fas and Fas ligand receptors (FasL), periapoptotic markers of gastric mucosa lymphocytes before and after H. pylori eradication. Forty nine patients aged 6 to 17 years, investigated due to chronic abdominal pain, were studied. The obtained tissue samples were analysed by immunohistochemistry. Different lymphocyte subsets were quantified on the basis of surface antigen expression (CD3, CD4, CD8, CD20), secreted cytokines (IL-4, IL-6, IFNγ) and Fas and FasL proteins in the gastric mucosa. B and T helper lymphocytes were found to play a major role in the inflammatory infiltration in the gastric mucosa in children during H. pylori infection. Their expression was found to decrease after eradication. The enhanced expression of Fas receptor on lymphocytes before treatment and a decrease of this expression after eradication of H. pylori were shown. It was demonstrated that there is a correlation between CD4 and Fas receptor expression that may induce apoptosis of the helper lymphocytes in infected children.

10

Efficacy of Helicobacter pylori eradication taking into account its resistance to antibiotics

84%

Ziemniak W.

Journal of Physiology and Pharmacology. Supplement

|

2006

|

tom 57

|

nr 3

123-141

The discovery of Helicobacter pylori (H. pylori) provided a possibility to cure effectively patients with peptic ulcers. Recent studies have shown varying susceptibility of H. pylori strains to antibiotics and increasing resistance to some of the recommended drugs. The purpose of the present study was to evaluate the efficacy of the currently recommended eradication schemes and to assess the increasing resistance of H. pylori strains to recommended antibiotics. Furthermore, the effect of probiotics (Lacidofil) on the efficacy of first-line treatment with amoxicillin and clarithromycin was analyzed. The study population consisted of 641 patients: 192 received amoxicillin with clarithromycin and proton pump inhibitor (PPI), 241 - tetracycline, tinidazole, bismuth and PPI, 53 - amoxicillin with clarithromycin and PPI supplemented with Lacidofil. The efficacy of eradication treatment was evaluated by the 13C-urease breath test. The microbiological examination included 111 samples of H. pylori. The present study demonstrated low efficacy of the tetracycline, tinidazole, bismuth and PPI scheme i.e. 71.4%, moderate efficacy of the amoxicillin with clarithromycin and PPI scheme i.e. 85.9%, whereas the supplementation with Lacidofil significantly increased the efficacy of eradication to 94.3%. The microbiological examination revealed a relatively high level of primary resistance to clarithromycin (22.2%) and a high level to metronidazole (46.7%), with no resistance to amoxicillin. However, the most important finding is the high level of secondary resistance to clarithromycin and metronidazole (more than 66% in both cases). The present findings suggest the need for modification of the recommended eradication schemes.

11

Inhibition of growth of Helicobacter pylori by omeprazole and clarithromycin enhanced by potassium sorbate

84%

Popowski J., Grodowska A., Kafel S.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 1

12

Cost-effectiveness of H. pylori eradication

84%

Roesch W.

Journal of Physiology and Pharmacology

|

1996

|

tom 47

|

nr 1

13

Therapy of H.pylori infection

84%

Bazzoli F., Pozzato P.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 4

14

Helicobacter pylori infection and gastric secretion in duodenal and gastric ulcer patients - the effect of eradication after one year

84%

Laszewicz W., Zaremba-Woroniecka A., Gabryelewicz A.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 1

15

Therapy of Helicobacter pylori infection

84%

Bazzoli F.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 1

16

Effect of H.pylori eradication on gastric and gallbladder emptying in non ulcer dyspepsia [NUD] patients

84%

Lorens K., Pawlik T., Thor P., Konturek S. J.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 1

17

Helicobacter pylori eradication in duodenal ulcer disease in cost-beneficial: a Belgian model

84%

Deltenre M., Ilunga K. O.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 4

18

Gastric and duodenal mucosa in children with duodenal ulcer before and after eradication of Helicobacter pylori

84%

Bak-Romaniszyn L., Planeta-Malecka I., Kulig A., Czkwianianc E., Suski S.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 1

19

Multicenter evaluation of dual-therapy [omeprazol and amoxycillin] for Helicobacter pylori-associated duodenal and gastric ulcer. [Two years of the observation]

84%

Gabryelewicz A., Laszewicz W., Dzieniszewski J., Ciok J., Marlicz K., Bielecki D., Popiela T., Legutko J., Knapik Z., Poniewierka E.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 4

20

Ranitidine bismuth citrate plus clarithromycin for eradication of H.pylori

84%

Dixon J. S., Pipkin G., Mills J. G., Wood J. R.

Journal of Physiology and Pharmacology. Supplement

|

1997

|

tom 48

|

nr 1

Ograniczanie wyników

The eradication of enzootic bovine leucosis in a large farm population

Guidelines in the medical treatment of Helicobacter pylori infection

Eradication of scabies on a swine farm with the use of the preparation invermectin 1 percentage [Biowet Gorzow]

Helicobacter pylori eradication and antral intestinal metaplasia - two years follow-up study

The influence of cholecystokinin on gastric myoelectrical activity in duodenal ulcer following Helicobacter pylori eradication - an electrogastrographic study

Ranitidine bismuth citrate plus clarithromycin for the eradication of H.pylori

Helicobacter pylori eradication: direct costs implication in gastric duodenal diseases

The sterile insect technique as a component of sustainable area-wide integrated pest management of selected horticultural insect pests

Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children

Efficacy of Helicobacter pylori eradication taking into account its resistance to antibiotics

Inhibition of growth of Helicobacter pylori by omeprazole and clarithromycin enhanced by potassium sorbate

Cost-effectiveness of H. pylori eradication

Therapy of H.pylori infection

Helicobacter pylori infection and gastric secretion in duodenal and gastric ulcer patients - the effect of eradication after one year

Therapy of Helicobacter pylori infection

Effect of H.pylori eradication on gastric and gallbladder emptying in non ulcer dyspepsia [NUD] patients

Helicobacter pylori eradication in duodenal ulcer disease in cost-beneficial: a Belgian model

Gastric and duodenal mucosa in children with duodenal ulcer before and after eradication of Helicobacter pylori

Multicenter evaluation of dual-therapy [omeprazol and amoxycillin] for Helicobacter pylori-associated duodenal and gastric ulcer. [Two years of the observation]

Ranitidine bismuth citrate plus clarithromycin for eradication of H.pylori