Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: dihydroxybenzoic acid

Sortuj według:

Ogranicz wyniki do:

Increased synthesis of dihydroxybenzoic acid in the presence of aluminium by Rhizobium MO1

100%

De M., Basu M., Chakrabartty P. K.

Acta Microbiologica Polonica

2003

tom 52

nr 2

The lactate receptor (HCAR1/GPR81) contributes to doxorubicin chemoresistance via ABCB1 transporter up-regulation in human cervical cancer HeLa cells

84%

Wagner W., Kania K. D., Blauz A., Ciszewski W. M.

Journal of Physiology and Pharmacology

2017

tom 68

nr 4

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Antioxidative effects of phenolic compounds of mushroom mycelia in simulated regions of the human colon, in vitro study

84%

Vamanu E., Pelinescu D., Avram I.

Polish Journal of Food and Nutrition Sciences

2018

tom 68

nr 1

Many compounds in mushrooms are biologically active; however, the in vivo actions of their metabolites are poorly understood. An in vitro system, GIS1, was used to simulate the fermentation action of microbiota in each colon region. We used MycoPo, a natural product obtained from the lyophilized mycelia of different Pleurotus ostreatus species to determine the biological effects in human-colon regions. Controls (Lentinula edodes mycelia; dried basidia of Agaricus brunnescens) were chosen to confi rm the biological activity of P. ostreatus mycelia in vitro. We measured total antioxidant capacity and ferric ion-reducing antioxidant power (FRAP) in simulated colon regions to identify antioxidant compounds, and undertook in vitro gastrointestinal simulation and microbiological analyses. The highest FRAP was found for the ascending colon, and the antioxidant effect was higher when MycoPo was administered. A. brunnescens consumption resulted in low total antioxidant capacity. Polyphenol content was correlated with the antioxidant status and microbial composition of microbiota. Total polyphenolic content was higher after A. brunnescens consumption, and four types of polyphenols were identifi ed by high-performance liquid chromatography. Major phenolic acids were gentisic acid, homogentisic acid, and small amounts of caffeic acid. The Enterobacteriaceae species populations varied greatly across the three parts of the colon. We noted a signifi cant (p<0.01) correlation between antioxidant status in the transverse and descending colon after MycoPo administration, and A. brunnescens consumption with the number of Lactobacillus and Bifi dobacteria species (R2 >0.85). These data suggest a direct relationship between favorable bacterial strains and availability of bioactive compounds, with specifi city for each colon region.

Ograniczanie wyników

1 Acta Microbiologica Polonica

1 Journal of Physiology and Pharmacology

1 Polish Journal of Food and Nutrition Sciences

1 Avram I.

1 Basu M.

1 Blauz A.

1 Chakrabartty P. K.

1 Ciszewski W. M.

1 De M.

1 Kania K. D.

1 Pelinescu D.

1 Vamanu E.

1 Wagner W.

1 2018

1 2017

1 2003

Wyniki wyszukiwania

Increased synthesis of dihydroxybenzoic acid in the presence of aluminium by Rhizobium MO1

The lactate receptor (HCAR1/GPR81) contributes to doxorubicin chemoresistance via ABCB1 transporter up-regulation in human cervical cancer HeLa cells

Antioxidative effects of phenolic compounds of mushroom mycelia in simulated regions of the human colon, in vitro study