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  1. 15 Archivum Immunologiae et Therapiae Experimentalis

  2. 4 Journal of Physiology and Pharmacology

  3. 3 Folia Histochemica et Cytobiologica

  4. 3 Journal of Physiology and Pharmacology. Supplement

  5. 2 Health Problems of Civilization

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  1. 4 Gorska M.

  2. 3 Brazert J.

  3. 3 Iciek R.

  4. 3 Kretowski A.

  5. 3 Luczynski W.

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  1. 1 2020

  2. 2 2019

  3. 1 2018

  4. 1 2017

  5. 2 2015

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1

Evaluation of lectin pathway activity and mannan-binding lectin levels in the course of pregnancy complicated by diabetes type 1, based on the genetic background

100%
Pertynska-Marczewska M., Cedzynski M., Swierzko A., Szala A., Sobczak M., Cypryk K., Wilczynski J.
Archivum Immunologiae et Therapiae Experimentalis
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2009
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tom 57
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nr 3
221-228
2

Apportioning blame: autoreactive CD4+ and CD8+ T cells in type 1 diabetes

100%
Varela‑Calvino R., Calvino-Sampedro C., Gomez-Tourino I., Cordero O. J.
Archivum Immunologiae et Therapiae Experimentalis
|
2017
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tom 65
|
nr 4
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Physioprophylaxis of type 1 diabetes in children using physical exercise

100%
Zaworski K., Lawnik A., Kubinska Z., Shpakou A.
Health Problems of Civilization
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2019
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tom 13
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nr 4
According to the Physiotherapist Act, physioprophylaxis is an important component of physiotherapy and of the physiotherapist’s professional activities. Physioprophylaxis can be oriented towards practicing healthy lifestyle behaviours, minimizing disease risk factors, or attenuating the consequences of the disease, surgery, and/or disability. Type 1 diabetes is a chronic metabolic disease characterized by hyperglycaemia, i.e. high blood glucose levels. It is caused by the dysfunction or destruction of β cells of pancreatic islets of Langerhans, which are responsible for the production and secretion of insulin. Type 1 diabetes is most common in children and adolescents. According to the 2018 report, 6,400 children aged 0-14 years and about 180,000 people over 14 years old suffer from type 1 diabetes in Poland alone. Physical activity is an important stimulus for optimal physiological development of children and adolescents, and is an important factor in reducing the risk of cardiovascular diseases, cancer, and mortality. Physical exercise reduces the need for insulin and increases the sensitivity of cells to insulin, so that the daily dose of insulin can be reduced. The Polish Diabetes Association recommends that children with type 1 diabetes should exercise for more than one hour a day in order to reduce the risk of vascular complications associated with the disease. The aim of this paper is to examine the effects of type 1 diabetes physioprophylaxis in children in the form of physical exercise, based on previous literature. The majority of research indicates physical activity has a positive effect on physiological function in children with type 1 diabetes, specifically reducing the risk of hypoglycaemia, high blood glucose level, insulin demand, and premature death.
4

Helicobacter pylori infection in type 1 diabetes children and adolescents using 13C urea breath test

100%
Chobot A., Bak-Drabik K., Skala-Zamorowska E., Krzywicka A., Kwiecien J., Polanska J.
Polish Journal of Microbiology
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2014
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tom 63
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nr 1
There is a 10–30% prevalence of HP infection in the general pediatric population in Poland. This study aimed to determine its prevalence in T1DM children in Upper Silesia, Poland and estimate its influence on metabolic control of patients. We studied 149(82♀) children with T1DM (duration > 12 months, mean HbA1c) and 298(164♀) age-matched controls. In all cases height and weight z-scores and Cole’s index were assessed. In T1DM patients additionally glycated hemoglobin A1c and T1DM duration were analyzed. Presence of HP infection was determined using 13C-isotope-labeled urea breath test (UBT) (fasting and 30min after ingestion 75 mg of 13C urea). HP infection was present in 17 (11.4%) T1DM patients and in 49 (16.4%) controls (p > 0.05). T1DM patients presented higher values of anthropometric parameters than healthy controls (weight SDS 0.25[–0.46÷0.84] vs. –0.25[–1.06÷0.26], height SDS 0.09[–0.60÷0.69] vs. –0.31[–1.17÷0.48]and Cole’s index 103%[93÷111%] vs. 97%[86÷106%]; for all p < 0001). Within both groups – T1DM children and controls – no differences regarding sex, age and any of the anthropometric parameters were determined. T1DM duration and HbA1c showed no relationto prevalence of HP infection. Prevalence of HP infection in pediatric T1DM patients is similar to that of healthy peers and shows no relation to glycemic control.
5

Increasing incidence of diabetes mellitus type 1 in children - the role of environmental factors

100%
Mysliwiec M., Balcerska A., Zorena K., Jedrzejczyk A., Malinowska E., Mysliwska J.
Polish Journal of Environmental Studies
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2007
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tom 16
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nr 1
The incidence of diabetes type 1, a chronic autoimmune disease, may reach the status of an epidemic in the 21st century. The highest incidence of diabetes in the world is observed in Finland. However, in the last 8 years a dynamic rise has been observed in Poland, moving the country toward an intermediate level incidence classification. Environmental factors seem to play a part in the observed increase in diabetes incidence both in Poland and in the world since, by acting on genetically predisposed ground prompt to auto-aggression, they may provoke disease occurrence. The study was carried out on a group of 511 children aged 0-15 years (255 girls and 256 boys). During the period of analysis (1998-2005) almost a two-fold increase in the diabetes incidence rate was observed (1998-10.4 vs 2005-20.4). The identification of all the factors increasing the risk of diabetes mellitus type 1 shall allow for understanding of diabetes ethiopathogenesis, and thus might create a chance for development of new prevention strategies.
6

The influence of immune system stimulation on encapsulated islet graft survival

100%
Orlowski T., Godlewska E., Tarchalska M., Kinasiewicz J., Antosiak M., Sabat M.
Archivum Immunologiae et Therapiae Experimentalis
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2005
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tom 53
|
nr 2
7

Reestablishing T cell tolerance by antibody-based therapy in type 1 diabetes

84%
Morillon Y. M., Martin A., Gojanovich G., Wang B., Tisch R.
Archivum Immunologiae et Therapiae Experimentalis
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2015
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tom 63
|
nr 4
8

Low frequency of regulatory T cells in the peripheral blood of children with type 1 diabetes diagnosed under the age of five

84%
Szypowska A., Stelmaszczyk-Emmel A., Demkow U., Luczynski W.
Archivum Immunologiae et Therapiae Experimentalis
|
2012
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tom 60
|
nr 4
9

Role of TGF-beta in self-peptide regulation of autoimmunity

84%
Singh B., Krawetz M. D., De Lima R. M., Mukherjee R., Chaturvedi P., Lee-Chan E., Leiter E. H., Summers K. L.
Archivum Immunologiae et Therapiae Experimentalis
|
2018
|
tom 66
|
nr 1
10
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Comparison of nutrition knowledge in patients with type 1 and type 2 diabetes

84%
Luszczki E., Deren K., Sobek G.
Journal of Pre-Clinical and Clinical Research
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2015
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tom 09
|
nr 1
Introduction. Diabetes as a non-infectious chronic metabolic disease is a problem of the contemporary world, including Poland. Behaviour therapy plays an important role in its treatment, i.e. proper diet and regular physical activity. Patient’s knowledge of nutrition principles is also an essential complement to the treatment, reducing the risk of late complications of diabetes. Objective. Assessment of the nutrition knowledge of patients with type 1 and type 2 diabetes. Materials and method. The study involved 300 randomly selected patients from Rzeszów and the surrounding area (135 patients with type 1 diabetes and 165 patients with type 2 diabetes) aged 8–78.The analysis was made using a survey questionnaire prepared by the authors of the study, conducted in the period July – December 2011. Results. The survey revealed that patients with type 1 diabetes have greater nutrition knowledge and knowledge about diabetes than patients with type 2 diabetes. On the other hand, they are less likely to comply with the recommendations of the diet prescribed by a doctor or a dietician. Conclusions. Patients with diabetes, regardless of age, type of diabetes, gender, or disease duration require continuous broadening of diabetes knowledge. Systematic training will teach patients proper eating habits related to their diet and lifestyle.
11

Polymorphisms in the genes encoding TGF-beta1, TNF-alpha, and IL-6 show association with type 1 diabetes mellitus in the Slovak population

84%
Javor J., Ferencik S., Bucova M., Stuchlikova M., Martinka E., Barak L., Strbova L., Grosse-Wilde H., Buc M.
Archivum Immunologiae et Therapiae Experimentalis
|
2010
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tom 58
|
nr 5
385-393
12

Type 1 diabetes: prospective cohort studies for identification of the environmental trigger

84%
Ronningen K. S.
Archivum Immunologiae et Therapiae Experimentalis
|
2013
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tom 61
|
nr 6
13
Content available remote

Leptin gene, leptin gene polymorphisms and body weight in pregnant women with diabetes mellitus type I

84%
Iciek R., Wender-Ozegowska E., Seremak-Mrozikiewicz A., Drews K., Sodowski K., Pietryga M., Brazert J.
Journal of Physiology and Pharmacology. Supplement
|
2008
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tom 59
|
nr 4
19-31
14

Crosstalk between immunity system cells and pancreas. Transformation of stem cells used in the 3D bioprinting process as a personalized treatment method for type 1 diabetes

84%
Niedzwiedzka-Rystwej P., Wolacewicz M., Cywoniuk P., Klak M., Wszola M.
Archivum Immunologiae et Therapiae Experimentalis
|
2020
|
tom 68
|
nr 2
15
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Awareness among nursing students about care for children with type 1 diabetes

84%
Lawnik A., Panczuk A., Kubinska Z.
Health Problems of Civilization
|
2019
|
tom 13
|
nr 4
Background. Diabetes, due to its prevalence and the rapid increase in the number of new incidences, has been recognized as an epidemic of the 21st century. It is estimated that over 3 million people in Poland currently suffer from this disease. According to the Ministry of Health, the knowledge of the society about diabetes is too little and insufficient. The aim of the study was to investigate and present general and expert knowledge of nursing students about type 1 diabetes, taking into account the needs of a child and the specialist skills required to care for diabetic children. Material and methods. The study was conducted among the students of nursing at Pope John Paul II State School of Higher Education in Biała Podlaska. A questionnaire designed by the author was used in this study. Results. The respondents reported that they possess basic knowledge about type 1 diabetes and at the same time are willing to learn more. They recognize that a child with type 1 diabetes requires special support, therefore medical personnel, educators and physical education teachers should have relevant knowledge and skills about care for type 1 diabetic children. Conclusions. The majority of the students surveyed had a basic knowledge and skills enabling them to provide assistance to children with type 1 diabetes and are familiar with their needs. The significance of physical activity in the life of a child with type 1 diabetes was known to a lesser extent. The students surveyed are willing to broaden their knowledge about type 1 diabetes.
16

Percentage of LFA-1plus and ICAM-1plus peripheral blood mononuclear cells in children and adolescents with type 1 diabetes does not distinguish patients with vascular complications

84%
Pawlowski P., Urban M., Stasiak-Barmuta A., Mysliwiec J., Pawlowska M.
Folia Histochemica et Cytobiologica
|
2009
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tom 47
|
nr 2
243-247
17
Content available remote

Placental leptin and its receptor genes expression in pregnancies complicated by type 1 diabetes

84%
Iciek R., Wender-Ozegowska E., Zawiejska A., Mikolajczak P., Mrozikiewicz P. M., Pietryga M., Brazert J.
Journal of Physiology and Pharmacology
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2013
|
tom 64
|
nr 5
18
Content available remote

Renal hyaluronan content during experimental uncontrolled diabetes in rats

84%
Rugheimer L., Carlsson C., Johnsson C., Hansell P.
Journal of Physiology and Pharmacology
|
2008
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tom 59
|
nr 1
With diabetes mellitus, the ability of the kidneys to maintain fluid balance is affected. Hyperglycaemia increases production of hyaluronan in cultured kidney cells implying that diabetes promotes induction of hyaluronan in the kidney. The aim of the present study was to determine if the interstitial matrix component hyaluronan is differently distributed within the kidney in diabetic rats compared to non-diabetic rats. Furthermore, to test if diabetic rats are able to respond with diuresis upon a hypotonic fluid load. The normal heterogeneous intrarenal distribution of hyaluronan was confirmed in non-diabetic control rats, with 60-fold more in the papilla than in the cortex. In diabetic animals, the cortical hyaluronan was unaffected but the papillary hyaluronan content was 3-fold higher than in non-diabetic rats. This increase correlated with a more than three-fold induction of the papillary hyaluronan-synthase 2 mRNA expression. In non-diabetic animals, 2 h water loading increased papillary hyaluronan (+93%) and diuresis (17-fold). In diabetic animals, baseline diuresis was 8-fold higher than in non-diabetic animals, which correlated with hyperglycaemia, glucosuria and proteinuria. Water loading in diabetic animals did not further increase papillary hyaluronan or diuresis: the urine flow rate decreased. To conclude, papillary hyaluronan is elevated in diabetic rats, which coincides with induction of hyaluronan-synthase 2 mRNA, hyperglycaemia, glucosuria, proteinuria and overt diuresis. The inability to respond to a water load with further diuresis may be related to the already elevated papillary hyaluronan and the inability to change hyaluronan during water loading.
19

Targeting Janus kinase 3 in the treatment of leukemia and inflammatory diseases

84%
Cetkovic-Cvrlje M., Uckun F. M.
Archivum Immunologiae et Therapiae Experimentalis
|
2004
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tom 52
|
nr 2
20

Immunotherapy of type 1 diabetes

84%
Li L., Yi Z., Tisch R., Wang B.
Archivum Immunologiae et Therapiae Experimentalis
|
2008
|
tom 56
|
nr 4
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