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GNAS1 mutation analysis in gastrointestinal tumors

100%

Walther B. M., Walther I., Chen J., Petersen I.

Folia Histochemica et Cytobiologica

2014

tom 52

nr 2

Expression and activity of superoxide dismutase isoenzymes in colorectal cancer

67%

Skrzycki M., Majewska M., Podsiad M., Czeczot H.

Acta Biochimica Polonica

2009

tom 56

nr 4

663-670

The aim of the study was an evaluation of changes in protein level and activity of SOD isoenzymes, and the participation of AP-1 and NF-κB in subsequent stages of colorectal cancer development. Studies were conducted on 65 colorectal cancers. Controls were unchanged colon regions. Activity of SOD isoenzymes, lipid peroxidation level (TBARS), and protein level of SOD1, SOD2, AP-1 and NF-κB were determined. We found that the protein level and activity of SOD isoenzymes and protein level of AP-1 and NF-κB change in subsequent stages of clinical advancement of colorectal cancer, according to UICC (I-IV), and in grades of tumor cells differentiation (G1-G3). These results indicate adaptation of colorectal cancer cells to oxidative stress, and show that the observed changes of SOD activity and protein level depend on gradual progression of colorectal cancer, and suggest an impairment of processes regulated by AP-1 and NF-κB which are critical for tumor progression (proliferation, differentiation and apoptosis).

Cell-specific cytotoxic effect of pyrazole derivatives on breast cancer cell lines MCF7 and MDA-MB-231

67%

Lehmann T. P., Kujawski J., Kruk J., Czaja K., Bernard M. K., Jagodzinski P. P.

Journal of Physiology and Pharmacology

2017

tom 68

nr 2

Fas/FasL expression in colorectal cancer. An immunohistochemical study

67%

Pryczynicz A., Guzinska-Ustymowicz K., Kemona A.

Folia Histochemica et Cytobiologica

2010

tom 48

nr 3

Ograniczanie wyników

2 Folia Histochemica et Cytobiologica

1 Acta Biochimica Polonica

1 Journal of Physiology and Pharmacology

1 Bernard M. K.

1 Chen J.

1 Czaja K.

1 Czeczot H.

1 Guzinska-Ustymowicz K.

1 Jagodzinski P. P.

1 Kemona A.

1 Kruk J.

1 Kujawski J.

1 Lehmann T. P.

1 Majewska M.

1 Petersen I.

1 Podsiad M.

1 Pryczynicz A.

1 Skrzycki M.

1 Walther B. M.

1 Walther I.

1 2017

1 2014

1 2010

1 2009

Wyniki wyszukiwania

GNAS1 mutation analysis in gastrointestinal tumors

Expression and activity of superoxide dismutase isoenzymes in colorectal cancer

Cell-specific cytotoxic effect of pyrazole derivatives on breast cancer cell lines MCF7 and MDA-MB-231

Fas/FasL expression in colorectal cancer. An immunohistochemical study