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1

Ranitidine bismuth citrate plus clarithromycin for the eradication of H.pylori

100%
Dixon J. S., Pipkin G. A., Mills J. G., Wood J. R.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 4
2
Content available remote

Efficacy of Helicobacter pylori eradication taking into account its resistance to antibiotics

84%
Ziemniak W.
Journal of Physiology and Pharmacology. Supplement
|
2006
|
tom 57
|
nr 3
123-141
The discovery of Helicobacter pylori (H. pylori) provided a possibility to cure effectively patients with peptic ulcers. Recent studies have shown varying susceptibility of H. pylori strains to antibiotics and increasing resistance to some of the recommended drugs. The purpose of the present study was to evaluate the efficacy of the currently recommended eradication schemes and to assess the increasing resistance of H. pylori strains to recommended antibiotics. Furthermore, the effect of probiotics (Lacidofil) on the efficacy of first-line treatment with amoxicillin and clarithromycin was analyzed. The study population consisted of 641 patients: 192 received amoxicillin with clarithromycin and proton pump inhibitor (PPI), 241 - tetracycline, tinidazole, bismuth and PPI, 53 - amoxicillin with clarithromycin and PPI supplemented with Lacidofil. The efficacy of eradication treatment was evaluated by the 13C-urease breath test. The microbiological examination included 111 samples of H. pylori. The present study demonstrated low efficacy of the tetracycline, tinidazole, bismuth and PPI scheme i.e. 71.4%, moderate efficacy of the amoxicillin with clarithromycin and PPI scheme i.e. 85.9%, whereas the supplementation with Lacidofil significantly increased the efficacy of eradication to 94.3%. The microbiological examination revealed a relatively high level of primary resistance to clarithromycin (22.2%) and a high level to metronidazole (46.7%), with no resistance to amoxicillin. However, the most important finding is the high level of secondary resistance to clarithromycin and metronidazole (more than 66% in both cases). The present findings suggest the need for modification of the recommended eradication schemes.
3

Inhibition of growth of Helicobacter pylori by omeprazole and clarithromycin enhanced by potassium sorbate

84%
Popowski J., Grodowska A., Kafel S.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 1
4

Therapy of H.pylori infection

84%
Bazzoli F., Pozzato P.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 4
5

Resistance of Helicobacter pylori to antibiotics

84%
Megraud F.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 1
6

Therapy of Helicobacter pylori infection

84%
Bazzoli F.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 1
7

Evaluation of omeprazole and amoxicillin or omeprazole and clarithromycin treatment in children with Helicobacter pylori gastritis or duodenal ulcer disease

84%
Iwanczak F., Potyrala M., Iwanczak B., Gosciniak G.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 1
8

Ranitidine bismuth citrate plus clarithromycin for eradication of H.pylori

84%
Dixon J. S., Pipkin G., Mills J. G., Wood J. R.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 1
9
Content available remote

Genotypic and clinical differences of seropositive Helicobacter pylori children and adults in the Polish population

67%
Iwanczak B., Laszewicz W., Iwanczak F., Dzierzanowska-Fangrat K., Rozynek M., Dzierzanowska D., Gosciniak G., Dlugosz J.
Journal of Physiology and Pharmacology
|
2014
|
tom 65
|
nr 6
10

Antimicrobial resistance of Helicobacter pylori clinical strains in the last 10 years

67%
Andrzejewska E., Szkaradkiewicz A., Karpinski T.
Polish Journal of Microbiology
|
2009
|
tom 58
|
nr 4
301-305
In the present work primary antimicrobial resistance was analyzed in clinical H. pylori strain isolates from adult patients from Polish Wielkopolska region within the last 10 years. Drug sensitivity was evaluated in a total of 142 H. pylori isolates, with 66 strains originating from years 1997/1998 forming group 1 and 76 strains isolated in 2007/2008 forming group 2. Sensitivity to amoxicillin, tetracycline, metronidazole and clarithromycin was determined by E-test. All strains were susceptible to amoxicillin and tetracycline. On the other hand, a high proportion of strains resistant to metronidazole was determined (36.4% in group 1 and 44.7% in group 2). In parallel, a growing tendency was discovered for resistance to clarithromycin (9.1% strains resistant in group 1 and 18.4% isolates resistant in group 2). The studies confirm the need for monitoring the drug resistance of Helicobacter pylori strains.
11
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Critical evaluation of the treatment of peptic ulcer diseases associated with Helicobacter pylori infection

59%
Gabryelewicz A.
Journal of Physiology and Pharmacology
|
1996
|
tom 47
|
nr 1
12
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Helicobacter pylori and impaired gastric secretory functions associated with duodenal ulcer and atrophic gastritis

59%
Konturek P. C., Konturek S. J., Bobrzynski A., Kwiecien N., Obtulowicz W., Stachura J., Hahn E. G., Rembiarz K.
Journal of Physiology and Pharmacology
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1997
|
tom 48
|
nr 3
13
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

One week treatment with omeprazole, clarithromycin and tinidazole or lansoprazole, amoxicillin and metronidazole for cure of Helicobacter pylori infection in duodenal ulcer patients

59%
Sito E., Konturek P. C., Bielanski W., Kwiecien N., Konturek S. J., Baniukiewicz A., Jedynak M., Gabryelewicz A., Hahn E. G.
Journal of Physiology and Pharmacology
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1996
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tom 47
|
nr 1
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