Wyniki wyszukiwania

1

Protein phosphorylation and signal transduction

100%

Krebs E. G.

Cellular and Molecular Biology Letters

|

1998

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tom 03

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nr 3

2

Cellular organisation and functions of the olfactory epithelium of pearl spot Etroplus suratensis (Bloch): a light and scanning electron microscopic study

75%

Ghosh S. K., Chakrabarti P.

Folia Morphologica

|

2010

|

tom 69

|

nr 3

The cellular organisation of the olfactory rosettes of Etroplus suratensis was studied by light and scanning electron microscopy. The oval shaped olfactory rosette of the fish consists of 12 lamellae radiating from a central raphe. The olfactory lamellae are comprised of restricted areas of sensory epithelium and broad areas of non-sensory epithelium in the apical, middle, and basal regions. The sensory epithelium contains three types of receptor cells: microvillus, ciliated, and rod cells, as well as labyrinth cells and supporting cells. The non-sensory epithelium consists of stratified epithelial and mucous cells. The transitional region between the sensory and non-sensory epithelium consists of ciliated receptor cells, mucous cells, and stratified epithelial cells. The different cells on the olfactory epithelium were discussed regarding the functional significance of the fish concerned. (Folia Morphol 2010; 69, 3: 154–159)

3

Function of glial cells in the development of the nervous system

75%

Wozniak W., Bruska M.

Acta Biologica Cracoviensia. Series Botanica. Supplement

|

2014

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tom 56

|

nr 1

4

Monolayers as model biomembranes

75%

Kinnunen P. K. J.

Cellular and Molecular Biology Letters

|

1999

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tom 04

|

nr 2

5

Membrane-active aminophosphonates

75%

Dziamska A., Sarapuk J.

Cellular and Molecular Biology Letters

|

2002

|

tom 07

|

nr 2

6

Multifunctional role of plant cysteine proteinases

75%

Grudkowska M., Zagdanska B.

Acta Biochimica Polonica

|

2004

|

tom 51

|

nr 3

Cysteine proteinases also referred to as thiol proteases play an essential role in plant growth and development but also in senescence and programmed cell death, in accumulation of storage proteins such as in seeds, but also in storage protein mobilization. Thus, they participate in both anabolic and catabolic processes. In addition, they are involved in signalling pathways and in the response to biotic and abiotic stresses. In this review an attempt was undertaken to illustrate these multiple roles of cysteine proteinases and the mechanisms underlying their action.

7

Bioelectrodynamics of cellular organization and interactions

63%

Cifra M.

Current Topics in Biophysics. Supplement

|

2011

|

tom 34

|

nr A: Plenary lectures

8

The toxic Doppelganger: on the ionic and molecular mimicry of cadmium

63%

Chmielowska-Bak J., Izbianska K., Deckert J.

Acta Biochimica Polonica

|

2013

|

tom 60

|

nr 3

Cadmium is a toxic heavy metal which can cause numerous alterations in cell functioning. Exposure to cadmium leads to generation of reactive oxygen species, disorders in membrane structure and functioning, inhibition of respiration, disturbances in ion homeostasis, perturbations in cell division, and initiation of apoptosis and necrosis. This heavy metal is considered a carcinogen by the Agency for Toxic Substances and Disease Registry. At least some of the described toxic effects could result from the ability of cadmium to mimic other divalent ions and alert signal transduction networks. This review describes the role of cadmium mimicry in its uptake, reactive oxygen species generation, alterations in calmodulin, Wnt/β-catenin and estrogen signaling pathways, and modulation of neurotransmission. The last section is dedicated to the single known case of a favorable function performed by cadmium mimicry: marine diatoms, which live in zinc deficient conditions, utilize cadmium as a cofactor in carbonic anhydrase - so far the only described cadmium enzyme.

9

Potassium channels in brain mitochondria

63%

Bednarczyk P.

Acta Biochimica Polonica

|

2009

|

tom 56

|

nr 3

385-392

Potassium channels are the most widely distributed class of ion channels. These channels are transmembrane proteins known to play important roles in both normal and pathophysiological functions in all cell types. Various potassium channels are recognised as potential therapeutic targets in the treatment of Parkinson's disease, Alzheimer's disease, brain/spinal cord ischaemia and sepsis. In addition to their importance as therapeutic targets, certain potassium channels are known for their beneficial roles in anaesthesia, cardioprotection and neuroprotection. Some types of potassium channels present in the plasma membrane of various cells have been found in the inner mitochondrial membrane as well. Potassium channels have been proposed to regulate mitochondrial membrane potential, respiration, matrix volume and Ca2+ ion homeostasis. It has been proposed that mitochondrial potassium channels mediate ischaemic preconditioning in various tissues. However, the specificity of a pharmacological agents and the mechanisms underlying their effects on ischaemic preconditioning remain controversial. The following potassium channels from various tissues have been identified in the inner mitochondrial membrane: ATP-regulated (mitoKATP) channel, large conductance Ca2+-regulated (mitoBKCa) channel, intermediate conductance Ca2+-regulated (mitoIKCa) channel, voltage-gated (mitoKv1.3 type) channel, and twin-pore domain (mitoTASK-3) channel. It has been shown that increased potassium flux into brain mitochondria induced by either the mitoKATP channel or mitoBKCa channel affects the beneficial effects on neuronal cell survival under pathological conditions. Recently, differential distribution of mitoBKCa channels has been observed in neuronal mitochondria. These findings may suggest a neuroprotective role for the mitoBKCa channel in specific brain structures. This minireview summarises current data on brain mitochondrial potassium channels and the efforts to identify their molecular correlates.

10

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Possibilities and limitations of light microscopy in the study of the structure and function of a plant cell

63%

Kurczynska E.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

|

2015

|

tom 96

|

nr 1

11

Structural changes of mitochondria during free radical-induced apoptosis

63%

Wakabayashi T., Spodnik J. H.

Folia Morphologica

|

2000

|

tom 59

|

nr 2

The initial proposal for apoptosis stressed nuclear change (condensation of chromatin) and the intactness of intracellular organelles, including mitochondria, based on light and electron microscopic observations. However, data have accumulated to demonstrate that the opening of megachannels of mitochondrial membranes, resulting in the swelling of the organelles, notably by Ca²⁺ and free radicals, is the crucial step in the apoptotic processes of the cell. Application of fluorescent dyes to mitochondria, combined with flow cytometry, has made it possible to detect subtle changes in the structure and function of the organelles related to apoptosis. The present article overviews structural aspects of mitochondria related to apoptosis, including the free radical-induced formation of megamitochondria.

12

Redox control of cellular function by thioredoxin; a new therapeutic direction in host defence

63%

Nishinaka Y., Nakamura H., Masutani H., Yodoi J.

Archivum Immunologiae et Therapiae Experimentalis

|

2001

|

tom 49

|

nr 4

13

Comprehensive analysis of all triple helical repeats in beta-spectrins reveals patterns of selective evolutionary conservation

63%

Baines A. J.

Cellular and Molecular Biology Letters

|

2003

|

tom 08

|

nr 1

The spectrin superfamily (spectrin, α-actinin, utrophin and dystrophin) has in common a triple helical repeating unit of ~106 amino acid residues. In spectrin, α and β chains contain multiple copies of this repeat. β-spectrin chains contain the majority of binding activities in spectrin and are essential for animal life. Canonical β-spectrins have 17 repeats; β-heavy spectrins have 30. Here, the repeats of five human β-spectrins, plus β-spectrins from several other vertebrates and invertebrates, have been analysed. Repeats 1, 2, 14 and 17 in canonical β are highly conserved between invertebrates and vertebrates, and repeat 8 in some isoforms. This is consistent with conservation of critical functions, since repeats 1, 2 and 17 bind α-spectrin. Repeats 1 of β-spectrins are not always detected by SMART or Pfam tools. A profile hidden Markov model of β-spectrin repeat 1 detects α-actinins, but not utrophin or dystrophin. Novel examples of repeat 1 were detected in the spectraplakins MACF1, BPAG1 and plectin close to the actin-binding domain. Ankyrin binds to the C-terminal portion of repeat 14; the high conservation of this entire repeat may point to additional, undiscovered ligand-binding activities. This analysis indicates that the basic triple helical repeat pattern was adapted early in the evolution of the spectrin superfamily to encompass essential binding activities, which characterise individual repeats in proteins extant today.

14

Targeting signal transduction for disease therapy

63%

Levitzki A.

Cellular and Molecular Biology Letters

|

1998

|

tom 03

|

nr 3

15

Immunolocalization of calreticulin in the protoplasts and somatic embryos of Daucus carota L. grown in suspension culture

63%

Libik M.

Acta Biologica Cracoviensia. Series Botanica. Supplement

|

1999

|

tom 41

|

nr 1

16

Understanding evolution

63%

Barciszewski J., Legocki A. B.

Acta Biochimica Polonica

|

2001

|

tom 48

|

nr 2

17

New chemical approaches to tracing cellular signal transduction cascades

63%

Shokat K. M.

Cellular and Molecular Biology Letters

|

1998

|

tom 03

|

nr 3

18

Yeast Cu, Zn-superoxide dismutase [SOD] as an inhibitory subunit of protein kinase CK2alpha'

63%

Zielinski R., Abramczyk O., Zien P., Pilecki M., Kubinski K., Hellman U., Szyszka R.

Cellular and Molecular Biology Letters

|

2003

|

tom 08

|

nr 2A

19

4-Hydroxy-2,3-nonenal as a signal for cell function and differentiation

63%

Dianzani M. U., Barrera G., Parola M.

Acta Biochimica Polonica

|

1999

|

tom 46

|

nr 1

4-Hydroxy-2,3-nonenal (HNE) is a biologically active aldehydic end product of oxidative decomposition of w-3 and w-6 polyunsaturated fatty acids of membrane phospholipids, a process referred to as lipid peroxidation. HNE has been detected in several experimental and clinical conditions in which oxidative stress has been reported to occur and several authors have suggested that HNE and related 4-hydroxy-2,3-alkenals (HAKs) of different chain length may act not only as toxic and mutagenic mediators of oxidative stress-related injury but also as biological signals in normal and pathological conditions. In this paper we will review the literature supporting the concept that HNE and HAKs may act as signal molecules able to modulate biological events such as chemotaxis, signal transduction, gene expression, cell proliferation and cell differentiation.

20

Involvement of carbohydrates and antioxidant enzymes in the oxidative balance during drought and recovery: the eucalyptus case

51%

Correia B., Silva S., Jesus C., Valledor L., Dias M., Costa A., Santos C., Pinto G.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

|

2013

|

tom 94

|

nr 2

Ograniczanie wyników

Protein phosphorylation and signal transduction

Cellular organisation and functions of the olfactory epithelium of pearl spot Etroplus suratensis (Bloch): a light and scanning electron microscopic study

Function of glial cells in the development of the nervous system

Monolayers as model biomembranes

Membrane-active aminophosphonates

Multifunctional role of plant cysteine proteinases

Bioelectrodynamics of cellular organization and interactions

The toxic Doppelganger: on the ionic and molecular mimicry of cadmium

Potassium channels in brain mitochondria

Possibilities and limitations of light microscopy in the study of the structure and function of a plant cell

Structural changes of mitochondria during free radical-induced apoptosis

Redox control of cellular function by thioredoxin; a new therapeutic direction in host defence

Comprehensive analysis of all triple helical repeats in beta-spectrins reveals patterns of selective evolutionary conservation

Targeting signal transduction for disease therapy

Immunolocalization of calreticulin in the protoplasts and somatic embryos of Daucus carota L. grown in suspension culture

Understanding evolution

New chemical approaches to tracing cellular signal transduction cascades

Yeast Cu, Zn-superoxide dismutase [SOD] as an inhibitory subunit of protein kinase CK2alpha'

4-Hydroxy-2,3-nonenal as a signal for cell function and differentiation

Involvement of carbohydrates and antioxidant enzymes in the oxidative balance during drought and recovery: the eucalyptus case