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Cell-mediated response in nodular and ocular forms of human toxoplasmosis

100%
Dziubek Z., Zarnowska H., Gorski A., Basiak W., Kajfasz P., Bielawska M.
Wiadomości Parazytologiczne
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1998
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tom 44
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nr 3
2

Virus-like particles as vaccine

86%
Chroboczek J., Szurgot I., Szolajska E.
Acta Biochimica Polonica
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2014
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tom 61
|
nr 3
3

Effects of cytostatics on the selected parameters of cell-mediated immunity in dogs

72%
Brodzki P., Wrona Z., Piech T., Brodzki A.
Bulletin of the Veterinary Institute in Puławy
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2011
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tom 55
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nr 1
The aim of the study was to assess the effects of tamoxifen and cyclophosphamide on the selected cell-mediated immunity parameters in dogs. The study included 18 dogs aged 5-10 years. The experimental group consisted of 12 animals with neoplastic lesions classified as the first or second staging group (according to the WHO TMN classification). This group was divided into two subgroups: I - six dogs receiving oral tamoxifen, and II - six dogs with cyclophosphamide administered orally. The control group included six healthy dogs. The blood was sampled from the saphenous access vein two times at 14-d intervals before the drug administration, three times every 7 d during administration, and two times every 14 d after completion of the therapy. The basic blood tests were carried out and the subpopulations of TCD4+ and TCD8+ lymphocytes, and phagocytic activity of granulocytes and monocytes were determined using flow cytometry. It was found that tamoxifen induced a marked increase in WBC and neutrophil counts, increased phagocytic activity of monocytes, and changed the CD4+:CD8+ ratio (in favour of cytotoxic lymphocyte subpopulation). These findings indicated the stimulation of cell-mediated immunity mechanisms. Cyclophosphamide caused a substantial decrease in the overall leukocyte pool and reduced the percentage of cells activated for phagocytosis, both neutrophils and monocytes even after completion of its administration, which proves its immunosuppressive effects.
4

Relationships between territory quality and carotenoid-based plumage colour, cell-mediated immune response, and body mass in Great Tit Parus major nestlings

72%
Galvan I., Diaz L., Sanz J. J.
Acta Ornithologica
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2009
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tom 44
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nr 2
Plumage colour is classified as pigmentary or structural, depending on whether it is caused by pigments or by feather microstructure. However, recent findings indicate that carotenoid-based plumage colouration also reflects at UV-blue wavelengths and that the underlying structure is related to the reflectance properties of the yellow feathers. Thus, yellow plumage is based on interactions between structural and pigmentary components. This study investigated the relationships among the vegetation structure of breeding territories, both components of plumage colour, T-cell- mediated immune response and body mass of nestling Great Tits Parus major. By using a model of avian visual perception, we found that, while plumage yellowness was associated with mature vegetation, plumage brightness and UV- blue reflectance were related to immature habitats in territories. We noted considerable variability in the development of carotenoid-based colour components under different environmental conditions, as plumage yellowness, but not brightness or UV-blue reflectance, depends on the availability of carotenoids, which is assumed to be high in mature territories with high food abundance. Territorial features denoting mature territories were also related to high body mass and immune response in nestlings, but none of the colour components were related to these variables of the vegetation structure, suggesting that habitat quality is related to nestling body mass and immune response through mechanisms different from those through which it is related to colour.
5

Interleukin 10 and its role in the regulation of the cell-mediated immune response in syphilis

58%
Lusiak M., Podwinska J.
Archivum Immunologiae et Therapiae Experimentalis
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2001
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tom 49
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nr 6
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