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  1. 15 Journal of Physiology and Pharmacology. Supplement

  2. 13 Archivum Immunologiae et Therapiae Experimentalis

  3. 2 Journal of Physiology and Pharmacology

  4. 1 Acta Agrobotanica

  5. 1 Annals of Agricultural and Environmental Medicine

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  1. 4 Drosdzol A.

  2. 4 Malolepszy J.

  3. 4 Skrzypulec V.

  4. 3 Babusikova E.

  5. 3 Banovcin P.

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  1. 1 2017

  2. 1 2015

  3. 1 2012

  4. 4 2009

  5. 4 2008

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1
Content available remote

Intermittent hypoxia: mechanisms of action and some applications to bronchial asthma treatment

100%
Serebrovskaya T. V., Swanson R. J., Kolesnikova E. E.
Journal of Physiology and Pharmacology. Supplement
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2003
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tom 54
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nr 1
35-41
Being essentially cut off from the global scientific community, Ukrainian and Russian scientists have developed a new concept for the beneficial use of adaptation to artificial intermittent hypoxia in treating of many diseases. The basic mechanisms underlying intermittent hypoxic training were elaborated mainly in three areas: regulation of respiration, free radical production and mitochondrial respiration. Twenty-year experience of the application of intermittent hypoxic therapy for the treatment of chronic obstructive bronchitis and bronchial asthma allows affirming that the adaptation to this kind of hypoxia causes a significant improvement of the clinical picture or even a complete recovery. The absence of negative side effects, typically observed during drug therapy, and the stimulation of organism’s general, nonspecific resistance, makes the hypoxic therapy a treatment with a future. A special note is devoted to the use of intermittent hypoxic training in industrial health care for the purpose of prophylaxis and treatment of professional diseases.
2
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Bond disorders of a patient with asthma: a case study

86%
Wilczynska-Kwiatek A.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
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nr 6
739-749
3

Abnormal eicosanoid-pattern of peripheral white-blood-cells in gastro-intestinal cancer

86%
Baenkler H. W., Schafer D.
Journal of Physiology and Pharmacology. Supplement
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2005
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tom 56
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nr 5
119-128
COX-inhibitors promote nasal polyps or bronchial asthma in individuals susceptible to an alteration of the pattern of the eicosanoids, especially leukotrienes and prostaglandins. This is associated with an abnormal release of eicosanoids from white blood cells. Since COX-inhibitors also protect from colorectal cancer an analogous association may be suggested. The study was performed to detect abnormal patterns of eicosanoids in white blood cells of patients with intestinal cancer compared to healthy controls. Seventy patients with intestinal cancer (stomach = 5; colon = 25; sigma = 18; rectum = 22) were compared to 62 healthy controls. Blood leukocytes from patients in complete long-lasting remission were incubated with diluent, arachidonic acid or acetylsalicylic acid. The synthesis of prostaglandin E2 and peptido-leukotrienes was quantified using competitive enzyme-immuno-assays and calculated for individual eicosanoid patterns. The mean basal and arachidonic- or acetylsalicylic acid-modulated PGE2 synthesis in patients was significantly higher than in controls (4.8-fold, 9.4-fold, 3.7-fold, respectively) whereas pLT was generally less elevated. We conclude that the eicosanoid-pattern of white-blood-cells from patients with intestinal cancer differs significantly from that in healthy individuals. This abnormal cellular metabolism may contribute to the manifestation of cancer and help to detect individuals at risk.
4

The effect of short-term and chronic glucocorticoid therapy on lymphocyte glucocorticoid receptor number in patients with asthma

86%
Grzanka A., Rogala B.
Archivum Immunologiae et Therapiae Experimentalis
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2003
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tom 51
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nr 5
5

The use of magnesium in bronchial asthma: a new approach to an old problem

86%
Kowal A., Panaszek B., Barg W., Obojski A.
Archivum Immunologiae et Therapiae Experimentalis
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2007
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tom 55
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nr 1
6
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Content available

Current glimpse of airborne allergenic pollen in Indian subcontinent

72%
Ghosal K., Gupta-Bhattacharya S.
Acta Agrobotanica
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2015
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tom 68
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nr 4
Respiratory allergic diseases such as bronchial asthma, rhinitis, urticaria, atopic dermatitis have been steadily increasing all over the world, including India. Owing to its alarming trend, several aerobiological surveys have been undertaken in different parts of India to delineate the variety of pollen and spore load. In this review, we have reported the current state of aerobiological knowladge in India with particular reference to allergenic airborn pollen occurence in 2001–2015. Pollen have been found to contribute a significant proportion in the air and caused allergy symptoms in the local inhabitants. Aerobiological records, a questionnaire survey and hospitalization records have been employed for the analysis. Holoptelea integrifolia, Amaranthus spinosus in northern region, Sorghum vulgare, Pennisetum, Gynandropsis gynandra, Parthenium hysterophorus, Dolichandrone platycalyx in southern regions, and Parthenium hysterophorus from the western region; Cynodon dactylon, Cenchrus ciliaris in the central area; Acacia auriculiformis, Cleome gynandra, Catharanthus roseus, Phoenix sylvestris, Areca catechu, and Lantana camara in the eastern regions as potential aeroallergens in India. The statistical approach confirmed the correlation between hospitalization rate associated with allergy-related health troubles and the prevalent allergenic pollen in the air. The Poaceae group has been found to be dominant throughout India. Immuno-biochemical studies identified various protein with allergenic potential found in the pollen recorded. Epitope identification and homology of the major allergenic protein Cat r1 of Catharanthus sp and Par j 1 of Parietaria judaica have been found. Identification of allergenic pollen grains and the modern approach concerning cross-reactivity and epitope revelation of dominant airborne pollen have important clinical implications for the prevention, diagnosis and treatments of allergic diseases in India.
7
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The influence of bronchial asthma on menstrual cycle

72%
Drosdzol A., Skrzypulec V., Wilk K., Rachel M.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
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nr 5
8
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Collagen receptors alpha1beta1 and alpha2beta1 integrins are involved in transmigration of peripheral blood eosinophils, but not mononuclear cells through human microvascular endothelial cells monolayer

72%
Bazan-Socha S., Zuk J., Plutecka H., Marcinkiewicz C., Zareba L., Musial J.
Journal of Physiology and Pharmacology
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2012
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tom 63
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nr 4
9
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Spirometry in preschool children: time has come for new reference values

72%
Kalhoff H., Breidenbach R., Smith H. J., Marek W.
Journal of Physiology and Pharmacology. Supplement
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2009
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tom 60
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nr 5
10
Content available remote

The influence of bronchial asthma on premenstrual syndrome prevalence among girls

72%
Skrzypulec V., Doniec Z., Drosdzol A., Nowosielski K., Pawlinska-Chmara R.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
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nr 5
11
Content available remote

Influence of selective inhibitors of phosphodiesterase 3 and 4 on couch and airway reactivity

72%
Mokry J., Mokra D., Nosalova G., Beharkova M., Feherova Z.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
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nr 6
473-482
12

The role of PTEN in allergic inflammation

72%
Lee Y. C.
Archivum Immunologiae et Therapiae Experimentalis
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2004
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tom 52
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nr 4
13

Beta-adrenergic stimulation does not influence the activity of lymphocyte Kv1.3 channels

72%
Teisseyre A., Gawlik A., Krasnowska M.
Cellular and Molecular Biology Letters
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1997
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tom 02
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nr 3
The aim of our study was to clarify the still controversial problem concerning the modulatory effect of β-adrenergic stimulation on the activity of Kv1.3 channels in human T Lymphocytes. Because the expression of β-adrenergic receptors in T Lymphocytes is significantly altered in patients with bronchial asthma we examined the cells taken both from healthy donors and asthmatic patients. We applied the whole-cell patch-clamp technique to study the modulatory effect of β-adrenergic stimulation on the whole-cell potassium conductance, gating and kinetics of Lymphocyte Kv1.3 channels. During the experiments β-adrenergic agonist Isoprenaline was applied at concentrations up to 10-4 M. It was shown that the activity of T lymphocyte Kv1.3 channels remain unchanged upon β-adrenergic stimulation both in cells taken healthy donors and asthmatic patients. Results of our investigations support the notion that β- adrenergic stimulation does not modulate the activity of Kv1.3 channels in human TL. The transient increase in T lymphocyte K+ channel activity upon β-adrenergic stimulation that has been reported in some previous studies is most probably due to an activation of recently identified, voltage-independent cAMP-responsive K+ channels.
14

Hydrogen peroxide in expired air condensate correlates positively with early steps of peripheral neutrophil activation in asthmatic patients

72%
Antczak A., Nowak D., Bialasiewicz P., Kasielski M.
Archivum Immunologiae et Therapiae Experimentalis
|
1999
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tom 47
|
nr 2
15

Inhaled natural human interferon alpha induces bronchospasticreaction in asthmatics

72%
Krasnowska M., Malolepszy J., Liebhart E., Inglot A. D.
Archivum Immunologiae et Therapiae Experimentalis
|
1992
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tom 40
|
nr 1
16

Eosinophil cationic protein in serum of corticosteroid-sensitive and resistant bronchial asthma

72%
Patkowski J., Wytrychowski K., Medrala W.
Archivum Immunologiae et Therapiae Experimentalis
|
1997
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tom 45
|
nr 2-3
17

Recent advances in understanding how interleukin 13 signals are involved in the pathogenesis of bronchial asthma

58%
Izuhara K., Umeshita-Suyama R., Akaiwa M., Shirakawa T., Deichmann K. A., Arima K., Hamasaki N., Hopkin J. M.
Archivum Immunologiae et Therapiae Experimentalis
|
2000
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tom 48
|
nr 6 Spec.Iss.
505-512
18
Content available remote

Asthma management at primary care level: symptoms and treatment of 3305 patients with asthma diagnosed by a family physician

58%
Doboszynska A., Swietlik E.
Journal of Physiology and Pharmacology. Supplement
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2008
|
tom 59
|
nr 6
231-241
19
Content available remote

Association of oxidative stress and GST-T1 gene with childhood bronchial asthma

58%
Babusikova E., Jesenak M., Kirschnerova R., Banovcin P., Dobrota D.
Journal of Physiology and Pharmacology. Supplement
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2009
|
tom 60
|
nr 5
20
Content available remote

Food allergens and respiratory symptoms

58%
Jesenak M., Rennerova Z., Babusikova E., Havlicekova Z., Jakusova L., Villa M. P., Ronchetti R., Banovcin P.
Journal of Physiology and Pharmacology. Supplement
|
2008
|
tom 59
|
nr 6
311-320
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