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1
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Blood coagulation characteristics in horses. The influence of breed

100%
Dabrowska J., Wisniewski E., Krumrych W., Danek J.
Bulletin of the Veterinary Institute in Puławy
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1997
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tom 41
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nr 2
This work aimed to assay the physiological values of basie blood coagulation indices and to determine the influence of breed on their range. Studies involved 105 horses of 6 breeds: Arabians, Thoroughbreds, Great Polish, Pony, Polish Primitive Horses and other breeds. It was found that under physiological conditions a mean coagulation time, kaolin-cephalin time, prothrombin time and thrombin time were 12.0 min, 124.0 s, 14.1 s, and 26.9 s, respectively. The concentration of fibrinogen was 3.48 g/ml and platelet count was 177 x 10⁹/1. Statistical analysis revealed that the breeds examined affected all the indices measured. The most efficienf mechanisms controlling haemostatis showed Thoroughbreds and Arabians contary to ponies Polish Primitive Horses.
2
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Changes in the blood coagulation profile after ovariohysterectomy in female dogs

84%
Sobiech P., Targonski R., Stopyra A., Zarczynska K.
Polish Journal of Veterinary Sciences
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2011
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tom 14
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nr 2
This study investigated changes in the coagulation profile of 10 healthy female dogs subjected to ovariohysterectomy. Blood samples were collected three times – before, directly after and 24 h after surgery. Plasma samples were analyzed to determine thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen content, D-dimer content and antithrombin (AT) III activity. The results revealed post-operative haemostatic system disorders related to prolonged APTT, higher fibrinogen and D-dimer concentrations and lower levels of AT III activity.
3
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Antithrombotic medications and their impact on fibrin clot structure and function

84%
Undas A., Zabczyk M.
Journal of Physiology and Pharmacology
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2018
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tom 69
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nr 4
4

Adenosine diphosphate receptors on blood platelets - potential new targets for antiplatelet therapy

84%
Rozalski M., Nocun M., Watala C.
Acta Biochimica Polonica
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2005
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tom 52
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nr 2
Platelets play a key role not only in physiological haemostasis, but also under pathological conditions such as thrombosis. Platelet activation may be initiated by a variety of agonists including thrombin, collagen, thromboxane or adenosine diphosphate (ADP). Although ADP is regarded as a weak agonist of blood platelets, it remains an important mediator of platelet activation evoked by other agonists, which induce massive ADP release from dense granules, where it occurs in molar concentrations. Thus, ADP action underlies a positive feedback that facilitates further platelet aggregation and leads to platelet plug formation. Additionally, ADP acts synergistically to other, even weak, agonists such as serotonin, adrenaline or chemokines. Blood platelets express two types of P2Y ADP receptors: P2Y1 and P2Y12. ADP-dependent platelet aggregation is initiated by the P2Y1 receptor, whereas P2Y12 receptor augments the activating signal and promotes platelet release reaction. Stimulation of P2Y12 is also essential for ADP-mediated complete activation of GPIIb-IIIa and GPIa-IIa, and further stabilization of platelet aggregates. The crucial role in blood platelet biology makes P2Y12 an ideal candidate for pharmacological approaches for anti-platelet therapy.
5
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Anticoagulative effects of the inhaled low molecular weight heparin certoparin in healthy subjects

67%
Scheuch G., Brand P., Meyer T., Herpich C., Mullinger B., Brom J., Weidinger G., Kohlhaufl M., Haussinger K., Spannagl M., Schramm W., Siekmeier R.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
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nr 5
6

Platelets in inflammation and immune modulations: functions beyond hemostasis

67%
Huang H.-S., Chang H.-H.
Archivum Immunologiae et Therapiae Experimentalis
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2012
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tom 60
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nr 6
7
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Effects of anaerobic exercise in the morning and evening sessions on some coagulation factors in non-athletes female students of Islamic Azad University of Sanandaj

67%
Tabatabai E. F., Hematfar A., Saeidian S.
International Letters of Natural Sciences
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2014
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tom 05
The purpose of the present research is compare the effects of coagulation factors in non-athletes gilrs after exhaustive anaerobic activity sessions in the morning and evening. Present study was semi-emprical that was done on 12 non-athlete female students in range of 18-24 years. Exercise protocol was RAST test, that in which each person passed amain 35 meters of distance for 6 times and rest 10 seconds between each stage. Blood sampling was performed Once in the morning (8 am) and a later week in evening (5 pm) in two stages (before and after). Datas were analyzed with Kolmogorov Smirnov test, Levine's test and two-way ANOVA level (p < 0/05 ). The results showed that there was not significative difference between the effects of an anaerobic activity in the morning and in the evening on hematocrit, platelet, partial time Thromboplastin (PTT), Prothrombin time (PT) and fibrinogen in non-athletic subjects. Findings showed that training for normal persons, non-athletes and patients, especially patients with clotting problems, and cardiovascular disease will be suggeste, each activity to be act with caution at morning and during the day.
8

Complement in cancer and cancer immunotherapy

67%
Kolev M., Towner L., Donev R.
Archivum Immunologiae et Therapiae Experimentalis
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2011
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tom 59
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nr 6
9

Purification and characterization of a heteromultimeric glycoprotein from Artocarpus heterophyllus latex with an inhibitory effect on human blood coagulation

67%
Siritapetawee J., Thammasirirak S.
Acta Biochimica Polonica
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2011
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tom 58
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nr 4
Plant latex has many health benefits and has been used in folk medicine. In this study, the biological effect of Artocarpus heterophyllus (jackfruit) latex on human blood coagulation was investigated. By a combination of heat precipitation and ion-exchange chromatography, a heat stable heteromultimeric glycoprotein (HSGPL1) was purified from jackfruit milky latex. The apparent molecular masses of the monomeric proteins on SDS/PAGE were 33, 31 and 29 kDa. The isoelectric points (pIs) of the monomers were 6.63, 6.63 and 6.93, respectively. Glycosylation and deglycosylation tests confirmed that each subunit of HSGPL1 formed the native multimer by sugar-based interaction. Moreover, the multimer of HSGPL1 also resisted 2-mercaptoethanol action. Peptide mass fingerprint analysis indicated that HSGPL1 was a complex protein related to Hsps/chaperones. HSGPL1 has an effect on intrinsic pathways of the human blood coagulation system by significantly prolonging the activated partial thrombin time (APTT). In contrast, it has no effect on the human extrinsic blood coagulation system using the prothrombin time (PT) test. The prolonged APTT resulted from the serine protease inhibitor property of HSGPL1, since it reduced activity of human blood coagulation factors XIa and α-XIIa.
10
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Effects of anaerobic exercise on some coagulation factors in non-athletes female students of islamic Azad University of Sanandaj

67%
Foroughi M., Tabatabai E. F.
International Letters of Natural Sciences
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2015
|
tom 39
The purpose of the present research is compare the effects of coagulation factors in nonathletes gilrs after exhaustive anaerobic activity .Present study was semi-emprical that was done on 12 non-athlete female students in range of 18-24 years. Exercise protocol was RAST test, that in which each person passed amain 35 meters of distance for 6 times and rest 10 seconds between each stage.Blood sampling was performed in two stages (before and after).Datas were analyzed with Kolmogorov Smirnov test, Levine's test and two-way ANOVA level (p < 0/05 ). The results showed that anaerobic exercise had a significant influence on partial time Thromboplastin (PTT), and fibrinogen in non-athletic subjects.But there was not significative difference on Prothrombin time (PT), platelet and hematocrit.Findings suggested that a meeting of anaerobic exercise on blood coagulation factor, effectiveness and changes in some of the invoices for training program Drafradghyrfal is important.
11

Wplyw zwiazkow chemicznych wystepujacych w napojach alkoholowych na hemostaze. Cz.II. Wplyw na uklad krzepniecia krwi

51%
Jurkowski J., Gacko M., Worowski K.
Bromatologia i Chemia Toksykologiczna
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1995
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tom 28
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nr 1
45-50
Określono wpływ 26 napojów alkoholowych, ich destylatów i pozostałości podestylacyjnej na aktywację protrombiny w systemie zewnątrzpochodnym i wewnątrzpochodnym oraz na aktywność trombiny.
12

Wplyw skladnikow suplementow diety - wapnia i magnezu na lepkosc fibryny nieusieciowanej

51%
Michalska M., Kolodziejska J.
Bromatologia i Chemia Toksykologiczna
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2006
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tom 39
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nr 2
173-178
13

Wplyw zwiazkow chemicznych wystepujacych w napojach alkoholowych na hemostaze. Cz.III. Wplyw na uklad fibrynolityczny osocza

51%
Jurkowski J., Gacko M., Worowski K.
Bromatologia i Chemia Toksykologiczna
|
1995
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tom 28
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nr 2
185-192
Określono wpływ 26 napojów alkoholowych, ich destylatów i pozostałości podestylacyjnych na aktywność fibrynolityczną i kazeinolityczną euglobulin osoczowych i plazminy.
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