Wyniki wyszukiwania

1

Histochemical and biochemical studies on the glutamate transmitter metabolism

100%

Wolf G.

Folia Histochemica et Cytobiologica

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1984

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tom 22

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nr 3-4

2

The role of PPAR gamma agonists - rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in experimental cyclosporine a hepatotoxicity

100%

Sikora-Wiorkowska A., Smolen A., Czechowska G., Wiorkowski K., Korolczuk A.

Journal of Physiology and Pharmacology

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2019

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tom 70

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nr 6

3

Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers

100%

Mozer-Lisewska I., Mania A., Kowala-Piaskowska A., Kluk A., Samara H., Pauli A., Zeromski J.

Archivum Immunologiae et Therapiae Experimentalis

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2014

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tom 62

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nr 2

4

Oxidative stress in standardbred horses during official races of 1600 and 2000 meters

100%

Piccione G., Fazio F., Giudice E.

Medycyna Weterynaryjna

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2007

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tom 63

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nr 12

1554-1557

In thoroughbred race horses, as in other species subjected to physical activity, there is a rise in the imbalance between free radical production and antioxidant agents which leads to oxidative stress. This stress may produce damage in several bio-molecules creating metabolic alterations affecting physical performance. The aim of this study was to find possible relationships between physical exercise and oxidative stress in trained horses. In order to achieve this we reported the results obtained while studying the effect of a physical exercise test on two groups of standardbreds. In particular, the study assessed levels of creatine kinase (CK) and aspartate amino transferase (AST) to evaluate possible muscle-cell membrane damage; reactive oxygen species (ROS), thiol antioxidant barrier (SHp) and antioxidant barrier (Oxy-adsorbent) to evaluate oxidative stress. Two groups of healthy standard bred (Ga and Gb) trained for 1600 and 2000 meter races were used for the study. Blood samples from all horses were collected at rest, immediately after racing, and 30 and 6 hours after racing. The ANOVA for repeated measures showed the highly significant effects of training on some of the studied parameters in both groups (Ga and Gb). Our results seem to indicate that in trained standard breeds acute exercise generates free radicals but they are unable to cause possible muscle-cell membrane damage. However, in order to know whether the inhibition of oxidative processes during exercise benefits physical performance, it would be necessary to simultaneously measure parameters relating to work capacity such as blood lactate, heart rate and oxygen consumption, both in basal conditions and at different times after a standardized race.

5

Seasonal changes in activity of some enzymes in the European bison Bison bonasus

100%

Gill J.

Acta Theriologica

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1992

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tom 37

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nr 3

6

Effect of pentoxifylline on biochemical parameters in endotoxaemic New Zealand white rabbits

100%

Yazar E., Col R., Uney K., Atalay B., Elmas M., Tras B.

Bulletin of the Veterinary Institute in Puławy

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2004

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tom 48

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nr 3

7

Genetic control of aspartate aminotransferase isoenzymes in Aegilops and Triticum species

100%

Maciaga M., Paszkowski A.

Journal of Applied Genetics

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2004

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tom 45

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nr 4

8

Zastosowanie izolowanych komorek watroby do oceny toksycznego dzialania substancji chemicznych

80%

Zapor L., Skowron J., Miranowicz-Dzierzawska K., Golofit-Szymczak M., Karlik W.

Bromatologia i Chemia Toksykologiczna

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1999

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tom 32

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nr 3

265-270

Na izolowanych hepatocytach w zawiesinie przeprowadzono ocenę cytotoksycznego działania etylobenzenu, n-heksanu i tetrachloroetylenu. Na podstawie oznaczania aktywności aminotransferazy asparaginowej w medium środowiskowym po inkubacji hepatocytów z badanymi związkami, dla każdego z nich obliczono wartość dawki CE50 którą następnie porównano z wartościami dawek LD50 uzyskanymi z badań na zwierzętach. Stwierdzono, że podobnie jak w doświadczeniach in vivo najsilniejsze działanie toksyczne wykazuje etylobenzen, następnie tetrachloroetylen i n-heksan.

9

The effects of long-term melatonin treatment on plasma liver enzymes levels and plasma concentrations of lipids and melatonin in patients with nonalcoholic steatohepatitis: a pilot study

80%

Gonciarz M., Gonciarz Z., Bielanski W., Mularczyk A., Konturek P. C., Brzozowski T., Konturek S. J.

Journal of Physiology and Pharmacology

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2012

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tom 63

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nr 1

10

Selected biochemical blood compounds in cows with abomasum displacement

80%

Markiewicz H., Gehrke M., Malinowski E.

Polish Journal of Veterinary Sciences

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2009

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tom 12

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nr 4

The aim of this study was to compare some blood biochemical indicators in cows with displacement of abomasum (DA) which recovered or died after treatment. Examinations were performed on 60 multiparous cows with left (L) or right (R) displacement and on 15 healthy herdmates. Diagnosis was made by experienced practitioners on the basis of clinical examination. Surgical treatment was undertaken during the first 24 hours after diagnosis. Almost all animals (55 = 91.5%) became sick in the post parturient period (21 days p.p. on average) with the exception of 5 (8.3%) that became sick later. Blood samples were taken from each cow immediately before surgical procedure. Serum nonesterified fatty acid (NEFA), glucose (Glu), cholesterol (Chol), aspartate aminotransferase (AST), total bilirubin (Bil) and blood urea nitrogen (BUN) were measured. Sick animals were characterized by low mean values of Chol (≤ 2 mmol/l) and normal level of BUN (12-15 mg/dl), higher levels of NEFA (> 600 μmol/l) and Bil (> 22 μmol/l), higher activity of AST (> 100 U/l). Seven cows (11.67%) died after surgical correction and all others recovered. No significant differences in NEFA, Chol, AST, Bil and BUN levels were observed as dependent on the efficacy of treatment (survival, deaths). It was found that cows which died after surgical treatment were characterized by significant higher levels of glucose (5.05 mmol/l) compared to surviving cows (2.93 mmol/l).

11

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The effect of long-term enrichment of diet with selenium, vitamin E and B15 on the activity of certain enzymes in rat brain

80%

Ziemlanski S., Puzynska L., Panczenko-Kresowska B.

Acta Physiologica Polonica

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1987

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tom 38

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nr 4

12

Biochemical profile, liver and kidney selenium (Se) status during acanthamoebiasis in a mouse model

80%

Lanocha-Arendarczyk N., Baranowska-Bosiacka I., Kot K., Pilarczyk B., Tomza-Marciniak A., Kabat-Koperska J., Kosik-Bogacka D.

Folia Biologica

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2018

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tom 66

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nr 1

13

Administration of low doses of tumor necrosis factor-alpha protects rat liver from ischaemic damage and reperfusion injury

80%

Helewski K. J., Kowalczyk-Ziomek G. I., Czecior E., Swietochowska E., Wielkoszynski T., Czuba Z. P., Szliszka E., Krol W.

Journal of Physiology and Pharmacology

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2010

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tom 61

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nr 3

273-278

Liver ischaemia and reperfusion (IR) injury is a significant clinical problem. The aim of our study was to investigate the protective effect of tumor necrosis factor-alpha (TNF-) on rat liver ischaemia-reperfusion injury. A TNF- dose of 3 µg/kg body weight was injected into rats that had undergone partial (70%) ischaemia and reperfusion. The activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), total blood antioxidant level (using the FRAP test), and the concentrations of TNF-, myeloperoxidase (MPO) and malondialdehyde (MDA) in liver homogenates after 1, 6, and 72 hours of reperfusion were measured. It was demonstrated that, rats subjected to IR, the administration of small doses of TNF- significantly reduced ALT and AST activities after 60- minute liver ischaemia and 1 or 6 hour of reperfusion. The strongest reductions in ALT and AST activities were seen after 1 hour of reperfusion (30% and 35%, respectively). Exogenous TNF- reduced the release of this cytokine in all observed periods, with the greatest reduction observed after 1 hour of reperfusion. Decreases in MPO concentration (by 40-45% in all periods of observation), as a marker of hepatic neutrophil infiltration, and in MDA concentration, the end-product of lipid peroxidation (by 55-60% at all time points), accompanied the reduction of TNF- release. The administration of TNF- to the rats after IR did not alter total plasma antioxidant potential, as assayed by the FRAP test, after 1 hour of reperfusion; however, at the later times a marked increase (~ 40-50%) occurred. We demonstrated that intraperitoneal injections of small doses of TNF- protect rat livers from IR injury. The mechanism of this protection is related to reductions in the release of TNF- during IR after injection of this cytokine, resulting in reductions in oxidative stress and inflammation during the later phase of reperfusion.

14

Nickel content in the coat of cats depending on their keeping conditions

80%

Kosla T., Skibniewska E., Skibniewski M.

Bulletin of the Veterinary Institute in Puławy

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2011

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tom 55

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nr 1

The investigations aimed at the assessment of nickel contamination of the environment based on the content of this element in the coat of domestic and feral cats. The content of nickel in the coat was determined using the method ICP-OES. While assessing the state of nickel supply, a trial was undertaken at checking whether the increase in nickel content in the animal organism affects biological and haematological indexes of the animal. Blood plasma alkaline phosphatase, and alanine and aspartate aminotransferase (transaminase) activities, and haematological parameters were analysed. Then, the correlations between those indexes and the nickel content in cats' hair depending on cats' keeping (feral and domestic cats) and their sex were calculated. No statistically significant differences were noted depending on the cats living conditions. The obtained mean value of nickel content in the coat could be accepted as normal for cats. In the case of nickel, the differences depending on sex and age were also not significant statistically. The assessment of statistical indexes shows that median, similarly as lower quartile, are identical for the nickel content in the cats from both groups (0.40 mg·kg⁻¹) independently from their sex and age. Analysis of nickel content depending on hair colour was also performed assuming that the colour depends on the saturation of hair with melanin. The lowest nickel content was observed in white hair, higher in tortoiseshell hair and black hair, and the highest in the feral colour - brownish grey. The results confirmed the fact that the content of nickel depends on the hair saturation with melanin.

15

Protective effects of melatonin against thioacetamide-induced liver fibrosis in rats

80%

Czechowska G., Celinski K., Korolczuk A., Wojcicka G., Dudka J., Bojarska A., Reiter R. J.

Journal of Physiology and Pharmacology

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2015

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tom 66

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nr 4

16

Exercise-induced biochemical alterations in the blood of horses involved in recreational horseback riding in Pomeranian Region (Northern Poland)

80%

Tkachenko H., Witaszek M., Pazontko-Lipinski P.

Baltic Coastal Zone. Journal of Ecology and Protection of the Coastline

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2018

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tom 22

The aim of our study was to determine changes in some biochemical indices (alanine (ALT) and aspartate aminotransferase (AST), lactate dehydrogenase (LDH)) as well as lactate and pyruvate level in the blood of horses exercised in recreational horseback riding from Pomeranian regions during a training session. Measurement of values of liver biomarkers (AST, ALT) and muscle damage indicator (LDH), followed by a variety of training programs, can help to better understand the acute and chronic effects of resistance training. Thirteen healthy adult horses from central Pomeranian region in Poland (village Strzelinko, N54°30'48.0" E16°57'44.9"), aged 9.5±2.4 years old, were used in this study. All horses participated in recreational horseback riding. Training started at 10.00 AM, lasted 1 hour and consisted from a ride of cross country by walking (5 min), trotting (15 min), walking (10 min), trotting (10 min), walking (5 min), galloping (5 min), and walking (10 min). Blood was drawn from jugular veins of the animals in the morning, 90 minutes after feeding, while the horses were in the stables (between 8.30 and 10.00 AM), and immediately after exercise session (between 11.00 AM and 2.00 PM). Blood was stored in tubes with K3-EDTA and sodium citrate (3.8%) and held on ice until centrifugation at 3,000 rpm for 15 minutes. The plasma was removed. Plasma was used for the determination of aminotransferases and lactate dehydrogenase activity; whole blood was used for determination of lactate and pyruvate level. The regular training lead to adaptive processes which provoke changes in biochemical indices. In our research, non-significant alterations of AST and LDH activities in horses involved in recreational horseback riding were observed. This may indicate a normal course of aerobic-anaerobic glycolysis in horses involved in recreational horseback riding during a training session. Moreover, ALT activity was decreased by 20.6% (p = 0.000) during a training session. Increased blood lactate level in horses involved in recreational horseback riding during training session could be explained by increasing lactate formation via the reduction of pyruvate catalyzed by LDH as a result of anaerobic energy supply. Based on these results, it is concluded that the endurance exercises lead to specific metabolic changes accompanied by a redistribution of energy supply for improving resistance to exercises and athletic performance of horses. Therefore, the present data can be useful to assess the status of athletes and the degree of their training adaptability providing an opportunity to modify the training schedule to achieve the desired performance.

17

Blood creatinine and some enzyme levels in four species of Indian carp fishes collected from a local aquatic body

80%

Kulkarni R., Pruthviraj C. B.

International Letters of Natural Sciences

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2016

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tom 60

18

Effect of ionizing radiation on tissue enzymes in pig liver and kidneys

80%

Dvorak P., Salplachta J., Zima S., Grolichova M., Musilova H.

Bulletin of the Veterinary Institute in Puławy

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2006

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tom 50

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nr 2

19

Biochemical indexes of the liver functioning at the acute stage of opisthorchiasis

80%

Bakshtanovskaya I., Stepanova T., Shonin A., Ponomareva O., Terekhina V.

Wiadomości Parazytologiczne

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1998

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tom 44

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nr 3

20

The effect of individual male variability on cryopreservation of bream [Abramis brama [L.]] sperm

80%

Glogowski J., Babiak I., Kucharczyk D., Luczynski M.

Polskie Archiwum Hydrobiologii

|

1997

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tom 44

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nr 1-2

Ograniczanie wyników

Histochemical and biochemical studies on the glutamate transmitter metabolism

The role of PPAR gamma agonists - rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in experimental cyclosporine a hepatotoxicity