Wyniki wyszukiwania

1

Comparison of microcytic and macrocytic anaemia based on the iron and vitamin B12 deficiency

100%

Wilczynska B., Marczyk A., Skibinska A., Kobak J., Jaroszewska M., Kozlowska K.

Acta Biologica Cracoviensia. Series Zoologia

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2008

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tom 50

49-56

2

Characteristic changes in erythrocyte nucleotides in haemolytic anaemia with basophilic stippling of differing aetiology

100%

Laurence A., Duley J. A., Simmonds H. A., Layton M.

Cellular and Molecular Biology Letters

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1999

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tom 04

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nr 3

3

Fetal outcome of pregnancy with anaemia in a rural set up

100%

Kawade V., Patil A.

Annals of Agricultural and Environmental Medicine

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1994

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tom 01

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nr 2

4

Relationship between anemia, iron deficiency, and platelet production in dogs

84%

Matur E., Ergul Ekiz E., Erek M., Ergen E., Kucuk S. H., Erhan S., Ozcan M.

Medycyna Weterynaryjna

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2019

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tom 75

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nr 06

Platelet production increases in anemic people. In particular, iron deficiency causes reactive thrombocytosis in such patients. Although anemia and iron deficiency are frequently seen in dogs, there are no published studies on this subject. The aim of the present study was to investigate the relationship between anemia, iron deficiency, and platelet production in dogs. A total of 81 dogs brought to the university animal hospital with signs of anemia were used. Haemogram parameters, serum iron (Fe), erythropoietin (EPO), and thrombopoietin (TPO) levels, as well as total iron binding capacity (TIBC), were measured. Transferrin saturation (TSAT) ratios were calculated. The animals were categorized as anemic or non-anemic, mildly anemic or moderately/ severely anemic, and having iron deficiency or no iron deficiency according to haemogram parameters and the serum Fe level. A high platelet number was observed in dogs with mild anemia. Dogs with mild anemia also had higher serum EPO levels than dogs with moderate/severe anemia (P = 0.047). Iron deficiency was detected in 31 dogs. The platelet number was higher in dogs with iron deficiency (P = 0.004). It was also observed that dogs with iron deficiency had higher serum EPO levels (P = 0.027) and lower TPO levels (P = 0.025) than dogs without iron deficiency. In conclusion, it can be said that mild anemia and iron deficiency cause thrombocytosis in dogs. The increased serum EPO levels, both in dogs with mild anemia and those with iron deficiency, suggest that the increase in platelet production is due to EPO. Nevertheless, there is a need for further research to fully understand the underlying mechanism.

5

The usefulness of soluble transferrin receptor (sTfR) in differentiating anemia occurring in young children

84%

Kamer B., Dolka E., Pasowska R., Swiatkowska E.

Folia Histochemica et Cytobiologica

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2012

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tom 50

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nr 3

6

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Iron in medicine and treatment

84%

Luchowska-Kocot D.

Journal of Elementology

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2014

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tom 19

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nr 3

Being a component of many proteins and enzymes, iron is an essential microelement for humans. However, this element can also be toxic when present in excess because of its ability to generate reactive oxygen species. This dual nature imposes a strict regulation mechanism of the iron concentration in the body. In humans, systemic iron homeostasis is mainly regulated on the level of intestinal absorption. A patient diagnosed with excess iron in the body should be treated safely and effectively. And the therapy should be consistent with the treatment of concurrent diseases. On the other hand, iron deficiency is one of the most common disorders affecting humans. Iron-deficiency anaemia continues to represent a major public health problem worldwide, being prevalent among pregnant women, where it represents an important risk factor for maternal and infant health. A problem detecetd relatively recently and therefore not fully clarified yet is the iron therapy in patients with restless legs syndrome (RLS). RLS is a common neurological condition defined clinically as the urge to move the legs. Reduced brain iron is strongly associated with restless legs syndrome. RLS can also be a consequence of iron deficiency in the body. This review will focus on iron as an element whose abnormal metabolism or deficiency in the body can lead to diseases e.g. anaemia, restless legs syndrome and iron overload. Here we will describe methods of therapy, paying particular attention to the types and dosages of medications.

7

Anemia prosiat - przyczyny i zapobieganie

84%

Mroczek J. R.

Biuletyn Informacyjno-Handlowy. Ośrodek Doradztwa Rolniczego Boguchwała

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2005

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nr 06

14

8

Serum concentrations of some acute phase proteins in cats with anaemia

84%

Tuna G. E., Dinler C., Ekren Asici G. S., Ulutas B.

Medycyna Weterynaryjna

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2018

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tom 74

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nr 09

Serum concentrations of acute phase proteins can provide valuable diagnostic information in the detection and monitoring of disease. The available information on the acute phase response in cats with anaemia is limited. The aim of this study was to retrospectively evaluate serum concentrations of haptoglobin, serum amyloid A, α1 acid glycoprotein and their clinical importance in cats with anaemia. Thirty-four anaemic cats and ten healthy cats were enrolled this study. After individual diagnoses had been established, the cats were divided into three groups (healthy group, haemolytic group and non-haemolytic group). Serum acute phase protein concentrations were analysed using specific commercially available test kits in an ELISA reader device. Serum amyloid A and serum α1 acid glycoprotein concentrations were significantly higher in the anaemic groups compared with the healthy group. Haptoglobin concentrations were significantly higher in cats from the non-haemolytic anaemia group than they were in healthy animals and those from the haemolytic anaemia group. Although serum haptoglobin concentrations were lower than in the healthy group, there was no significant difference between the haemolytic anaemia group and the healthy group. The results of this study suggest that serum amyloid A and α1 acid glycoprotein could be useful in the diagnosis and determination of inflammation in cats with anaemia. Serum haptoglobin depletion may be used for diagnosis of haemolysis in cats with haemolytic anaemia. In addition, this study has contributed to the limited data available on acute phase protein concentrations in cats with anaemia.

9

Systemic oxidative stress in Suffolk and Santa Ines sheep experimentally infected with Haemonchus contortus

84%

Baptistiolli L., Narciso L. G., de Almeida B. F. M., Bosco A. M., de Souza J. C., Torrecilha R. B. P., Pereira P. P., Figueiredo R. N., Garcia J. F., Kaneto C. N., Ciarlini P. C.

Acta Parasitologica

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2018

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tom 63

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nr 3

10

Influence of hepcidin on iron metabolism

84%

Kosla T., Skibniewska E. M.

Medycyna Weterynaryjna

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2010

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tom 66

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nr 05

291-293

The main role of iron is being part of haemoglobin, whose level it stabilizes; however, iron also plays a very important role in immunological processes and the metabolism of the organism. Hepcidin is a peptide hormone. It was first isolated from human blood and urine, and its release was attributed to the liver. A failure to produce hepcidin is related to iron overload, while its excessive production to anaemia caused by iron deficit. The releasing of hepcidin also affects hypoxia and inflammation through inhibiting these processes in patients with haemochromatosis. There are three forms of the regulation of the iron level: the first is a regulation in cellular storages, the second is erythropoiesis and the third is a dietary regulator. Hepcidin was identified as a regulator which communicates the level of iron reserves in the organism to intestine cells responsible for the absorption of iron. In inflammatory conditions, when the organism wishes to cause alimentary iron deficit, hepcidin production increases even a hundred fold, thus leading to anaemia. Hepcidin is also a stimulator of inflammation as an antibacterial factor produced in the liver parenchyma. It decreases the absorption of iron in the intestines and increases the secretion of iron to the reticuloendothelial system. Experiments on animals deprived of hepcidin and animals with its excess make it possible to understand iron homeostasis and confirm the role of hepcidin as a hormone regulating iron metabolism.

11

Biofortification - promising approach to increasing the content of iron and zinc in staple food crops

84%

Garcia-Banuelos M. L., Sida-Arreola J. P., Sanchez E.

Journal of Elementology

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2014

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tom 19

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nr 3

Micronutrient deficiencies have increased over recent decades due to the general depreciation of the quality of poor people’s diet, both in developed and developing countries. The deficiencies of iron (Fe) and zinc (Zn) are a critical public health problem worldwide, with the negative impact on health, lifespan and productivity. Biofortification is an agricultural approach that can improve human nutrition on a global scale. Agronomic biofortification is considered a short-term and complementary strategy, but economic analyses suggest that genetic biofortification is the most effective strategy for increasing dietary Fe and Zn intakes of vulnerable populations. Enrichment of cereal grains by breeding is a high-priority area of research, and an effective strategy among other approaches, e.g, fortification, supplementation and food diversification. This review discusses the role of Fe and Zn in plant nutrition, the potential strategies for developing Fe and Zn biofortified crops and their importance in human nutrition.

12

Effects of lead chloride on human erythrocyte membranes and on kinetic anion sulphate and glutathione concentrations

84%

Gugliotta T., De Luca G., Romano P., Rigano C., Scuteri A., Romano L.

Cellular and Molecular Biology Letters

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2012

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tom 17

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nr 4

Our study concerns the effects of exposure to lead chloride on the morphology, K+ efflux, SO4 − influx and GSH levels of the human erythrocyte. Blood was collected in heparinized tubes and washed three times. The cells were suspended at 3% hematocrit and incubated for 1 h at 25°C in a medium containing increasing concentrations of lead chloride (0, 0.3, 0.5 and 1 μM). After incubation, the suspensions were centrifuged and the erythrocyte pellets were divided into three aliquots for testing. The results show: an increase in the permeability of erythrocytes treated with lead chloride with consequent damage and cellular death, especially in the presence of high concentrations; an increase in potassium ion efflux; alterations in the morphology and membrane structure of the red blood cells; and a decrease in sulphate uptake, due either to the oxidative effect of this compound on the band 3 protein, which loses its biological valence as a carrier of sulphate ions, or to a decrease in the ATP erythrocyte concentration. In conclusion, the exposure of erythrocytes to Pb2+ ions leads to a reduction in the average lifetime of the erythrocytes and the subsequent development of anemia. These data are discussed in terms of the possible effect of lead on the reduction-oxidation systems of the cell. Oxidant agents, such as lead, are known to cross-link integral membrane proteins, leading to K/Cl-cotransport. The increased K+ efflux affects the altered redox state.

13

Prevalence of anemia in relation to socio-economic factors in elderly Polish population: the results of PolSenior study

84%

Styszynski A., Mossakowska M., Chudek J., Puzianowska-Kuznicka M., Klich-Raczka A., Neumann-Podczaska A., Szybalska A., Wieczorowska-Tobis K.

Journal of Physiology and Pharmacology

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2018

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tom 69

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nr 1

14

Iron deficiency anemia (IDA), their prevalence, and awareness among girls of reproductive age of distt mandi Himachal Pradesh, India

84%

Kumar R.

International Letters of Natural Sciences

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2015

|

tom 02

Anemia constitutes a public health problem, in both developed and developing countries with major burden on economic and social develop ment. Present study was designed to examine the prevalence of anemia among girl students of Abhilashi College, Distt Mandi Himachal Pradesh. Hemoglobin (Hb) level of 87 girls students was determined . Prevalence of anemia was detected to have been quite high at 55%. Self-awareness of the condition among those anemic was dismally low at 10%. Health education constitutes an important approach to increase awareness about anemia in terms of exposures, risk factors, essential nutrition ingredients an d the importance of iron supplementations. Thus, the present study has tried to focus on those issues which are responsible for determining the level of anemia among wo men aged 20 to 40 years and has also tried to provide scientific exp lanations of iron deficiency anemia.

15

Effects of haematophagous mites on nestling house sparrows [Passer domesticus]

84%

Szabo K., Szalmas A., Liker A., Barta Z.

Acta Parasitologica

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2002

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tom 47

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nr 4

Haematophagous mites are frequently found on nestling house sparrows (Passer domesticus), but their effects are poorly known. In this study we investigated whether natural levels of infection by two mite species Pellonyssus reedi and Ornithonyssus sylviarum have any fitness consequences on their hosts, including some physiological indices of chick health, body condition and fledging success. Among the haematological variables, thrombocytes and heterophils, but not lymphocytes and eosinophil granulocytes showed positive correlations with mite loads. There was also a significant decrease in the haematocrit values of the nestling sparrows with increasing mite intensity. We found no significant effect of ectoparasites on short- term indices of nestling fitness, such as body mass or fledging success. These results suggest that the blood-feeding mites of the studied house sparrow population mainly affected the haematological parameters of their hosts: They generated a non-specific immune response, with inflammatory processes and anaemia. On the other hand, parasite infestation seemingly has only weak influence on feather and skeletal growth of nestling sparrows, and no effect on fledging success and body mass.

16

Reticulocyte indices in the diagnosis of iron deficiency in suckling piglets

84%

Svoboda M., Ficek R., Drabek J.

Bulletin of the Veterinary Institute in Puławy

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2008

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tom 52

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nr 1

The aim of the study was to evaluate the usefulness of the reticulocyte indices in the diagnosis of anaemia in piglets. The piglets in group I (n=16) were treated with iron dextran (200 mg of Fe, i.m.) at the age of 16 d. In group II (n=16), piglets at the age of 3 d received 100 mg of Fe and then at the age of 22 d - 200 mg of Fe. The piglets in group III (n=16) received 200 mg of Fe at the age of 3 d. From the 7 d of age, all the piglets had access to creep feed. In group I, there was a decrease in red blood cell indices and the piglets developed anaemia. These piglets had a lower growth intensity compared to piglets of groups II and III. In comparison with Hb, PCV, and RBC, the reticulocyte indices (haemoglobin concentration in reticulocyte and index RET-Y) reflexed more rapidly impaired erythropoiesis and in the case of mild iron deficiency (group II) they reacted more effectively to iron treatment.

17

Ferr-Up in prophylaxis of piglet anaemia

84%

Zwierzchowski W., Gajecki M., Obremski K., Zielonka L.

Advances in Agricultural Sciences

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2002

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tom 08

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nr 1

18

Study of dynamics bee venom-induced shrinkage of erythrocytes of the patients with anemias of various etiology

84%

Nipot E. E., Dyryavy S. B., Cherepanov V. V.

Cellular and Molecular Biology Letters

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1998

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tom 03

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nr 2

19

Evaluation of the efficacy of iron polymaltose complex in the prevention of anaemia in piglets

84%

Svoboda M., Ficek R., Drabek J.

Bulletin of the Veterinary Institute in Puławy

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2008

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tom 52

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nr 1

The aim of this study was to evaluate the efficacy of oral application of iron polymaltose complex (IPC) in the prevention of iron deficiency in piglets. The piglets in group I (n = 15) were treated with iron dextran (200 mg of Fe³⁺, i.m.) at the age of 3 d. In group II (n = 19), the piglets were given 100 mg of Fe³⁺ as IPC orally at the age of 3 and 11 d. The piglets in group III (n = 19) received oral application of 100 mg of Fe²⁺ ferrous fumarate at the age of 3 and 11 d. The piglets in group IV (n = 12) served as an iron deficient control group. The haemoglobin concentration and iron concentration in blood plasma in IPC treated group were comparable to the ferrous fumarate group. It is concluded that the IPC showed a comparable efficacy of IPC in the anaemia prevention as ferrous fumarate.

20

Effect of bovine lactoferrin on utilization of orally administered iron in suckling piglets

84%

Svoboda M., Drabek J., Ficek R.

Bulletin of the Veterinary Institute in Puławy

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2005

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tom 49

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nr 4

Ograniczanie wyników

Comparison of microcytic and macrocytic anaemia based on the iron and vitamin B12 deficiency

Characteristic changes in erythrocyte nucleotides in haemolytic anaemia with basophilic stippling of differing aetiology

Fetal outcome of pregnancy with anaemia in a rural set up