Wyniki wyszukiwania

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The alcohol dependence and plasma selenium concentration

100%

Kucharska-Mazur J., Samochowiec J., Zawierta J., Chlubek D.

Acta Poloniae Toxicologica

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2000

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tom 08

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nr 2

2

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Review of research on alcohol dependence in a model of mice selected for high and low stress-induced analgesia

86%

Poznanski P., Lesniak A., Strzemecka J., Sacharczuk M.

Health Problems of Civilization

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2018

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tom 12

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nr 3

Decades of studies on alcohol dependence showed that it is a very complex and multifactorial disorder. Several receptor systems are involved in development and susceptibility to alcohol abuse; however, there are some which play a crucial role in its pathogenesis, e.g. dopaminergic or opioid system. In this paper, an effort is made to explain the role of endogenous opioid system activity in alcohol dependence. To achieve the goal, we use a unique model is used which shows mice lines that are divergently selected for high (HA) and low (LA) stress-induced analgesia. This process allowed for selecting individuals characterised by hyperactive (HA) or hypoactive (LA) opioid system. Basing on the performed experiments, we proved that delta opioid receptors play a critical role in the development of addiction. The most notable achievement is an unspecific reaction of mice with the hyperactive opioid system to naloxone – an unspecific opioid system antagonist, which is currently approved in the pharmacotherapy of dependent patients.

3

State of knowledge (concerning the alcohol dependence) of the patients undergoing a therapy in the Department of twenty-four-hour Addiction Treatment in Lukow

72%

Piaszczyk D., Baranowska T., Lawnik A.

Health Problems of Civilization

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2014

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tom 08

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nr 4

The aim of research was to determine the effects of therapy and its influence on the way people addicted to alcohol perceive alcoholism. This work contains the basic knowledge concerning the core of alcoholism, its stages and symptoms of addiction. There are also characteristic features of addicted person which resulted from the analysis of defense mechanisms supporting alcoholism. The research was carried out from November 2012 to January 2013 in the Department of Twenty-four-hour Addiction Treatment in Independent Public Health Care Institution in Łuków. The study comprised of 50 patients who were in the final stage of therapy (seventh week of therapy). The research tool was the interview questionnaire, prepared by the researchers, which consisted of questions concerning demographic-social data of patients, their knowledge, concerning dependence syndrome, and the level of preparedness for living with disease after the end of therapy. The research showed that men participated in the therapy four times more often than women. Half of the investigated patients completed only the primary education and had a status of an unemployed person. Basing on the conversations with patients, it was proved that the main reason for participation in the therapy was the desire to overcome their addiction. It has been stated that after 7 weeks of therapy more than ½ of patients gained knowledge concerning alcoholism and evaluated their own knowledge as sufficient. Thanks to the therapy, patients gained knowledge concerning the destructive influence of alcohol on the functioning of family. More than ½ of patients claimed that they are able to use assertive behaviours and prevent the recurrence of disease. According to patients, the instructor of therapy plays an important role in shaping some necessary skills at "building" a sober life.

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Dynamics of variations concerning age and sex of patients admitted to Alcohol Dependence Therapy Department (COTUA) of Neuropsychiatric Hospital in Lublin in 2000, 2001 and 2002

72%

Latalski M., Skorzynska H., Opielak G., Loza B., Pacian A., Sokol M.

Polish Journal of Environmental Studies

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2004

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tom 13

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nr Suppl.2, Part 1

Alcoholism is undoubtedly one of the most serious types of dependence. Its harmfulness is based on common character and degradation in family and professional functioning of individual suffered from alcohol dependence. Based on analysis of available data authors of this study made an attempt to check if there were any changes in average age and gender proportions among people reported to drying-out therapy during three consecutive years. One assumed that in the case of confirmation of advanced hypothesis, this study becomes an introduction to further researches.

5

Salivary lysozyme in smoking alcohol-dependent persons

72%

Waszkiewicz N., Zalewska-Szajda B., Zalewska A., Waszkiewicz M., Szajda S. D., Repka B., Szulc A., Kepka A., Minarowska A., Ladny J. R., Zwierz K.

Folia Histochemica et Cytobiologica

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2012

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tom 50