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Prolonged hyperadrenalinemia impairs exercise ability in rats

100%

Kozlowski S., Langfort J., Brzezinska Z., Pilis W., Kaciuba-Uscilko H., Nazar K., Porta S.

Acta Physiologica Polonica

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1987

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tom 38

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nr 6

2

Adrenal hormones and the regulation of acute phase protein synthesis

100%

Boers W., Smit R. A., Sala M., Maas A., Chamuleau R. A. F. M.

Folia Histochemica et Cytobiologica

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1992

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tom 30

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nr 4

3

Histological and histochemical study of the magnocellular neuroendocrine system in white rat after parenteral administration of adrenaline

100%

Arciszewska E., Borowska H., Niklinska W.

Folia Histochemica et Cytobiologica

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2001

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tom 39

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nr 2

4

Effect of adrenalin, insulin and contractions on the content of the free fatty acid fraction in skeletal muscle

100%

Chabowski A., Baranczuk E., Gorski J.

Journal of Physiology and Pharmacology

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2005

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tom 56

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nr 3

The fraction of free fatty acids (FFA) is present in skeletal muscles. However, there is almost no data regarding regulation in the content of this intramuscular lipid pool. We took advantage of the isolated muscle preparation to examine whether: a) increasing exogenous concentration of FFA (500µM or 700µM, 30min) b) insulin (10.00 I.U./L, 30min), c) adrenalin (4.4 nM, 30min), or d) contractions (200ms, tetani, 1Hz, 30min), affect the FFA content inside myocytes. Incubation of soleus (S) and extensor digitorum longus (EDL) with increasing concentrations of exogenous FFA (from 500µM to 700µM) resulted in an increase in the total FFA fraction in both muscles studied (by 280.2% and 259.1%, respectively). In contracting muscles FFA pool was significantly reduced both in S (by 73.1%) and in EDL (by 31.1%). Neither stimulation by adrenalin nor insulin affected the total content of FFA fraction in the muscles examined. We conclude that a) increased availability of exogenous FFA at the sarcolemma level results in an increase in the size of intramuscular FFA fraction b) the intracellular FFA fraction is utilized by contracting muscles with regard to the fiber composition and to a greater extent in more oxidative muscles, c) FFA fraction remains stable upon stimulation by insulin or adrenalin.

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Reverse 3,3',5'-triiodothyronine influences the hyperglycaemia in chickens induced by dexamethasone and exogenous glucose; Lack of effect on hyperglycaemia elicited by adrenaline

100%

Bobek S., Sechman A., Niezgoda J., Jacek T.

Roczniki Naukowe Zootechniki. Suplement

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2001

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tom 12

6

Relation of adrenergic receptors, which have roles in gastroprotective and anti-inflammatory effect of adrenal gland hormones, with cyclooxygenase enzyme levels in rats

84%

Suleyman H., Dursun H., Bilici M., Cadirci E., Halici Z., Gulaboglu M., Albayrak F.

Journal of Physiology and Pharmacology

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2009

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tom 60

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nr 4

129-134

Background and Aims: COX-2 enzyme inhibition is responsible for the anti-inflammatory effects of NSAIDs, COX-1 for their effects upon the gastrointestinal system (GIS), along with other side effects. We investigated the relationship between COX levels and those adrenergic receptors known to play a role in gastroprotection and anti-inflammatory activity. Method: The effects of adrenaline and prednisolone on gastric COX-1 and COX-2 levels in both intact and adrenalectomized rats treated with doxazosin, yohimbine, propranolol, and metoprolol were determined. Results: We found that adrenaline increases COX-1 levels in the gastric tissue of both intact and adrenalectomized rats by stimulating -2 receptors. Adrenaline decreases COX-2 levels by stimulating ß-2 adrenergic receptors. Prednisolone inhibits both COX-1 and COX-2 in the gastric tissue of intact rats. In adrenalectomized rats, prednisolone increases gastric COX-1 by stimulating -2 receptors, and decreases COX-2 levels by stimulating ß-2 receptors. Conclusion: Prednisolone cannot bind to a adrenergic receptors in the presence of adrenaline (intact rats) but, in its absence (adrenalectomy), binds to -2 receptors, and stimulates them more effectively than adrenaline, suggesting a direct relationship between -2 adrenergic receptors and COX-1 levels, whereas ß-2 receptors are directly related to COX-2 levels.

7

Neurosecretory and histological changes in hypothalamus and neural zone of pituitary gland in rats following hydrocortisone and adrenaline administration

84%

Ficek W.

Acta Biologica Cracoviensia. Series Zoologia

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1989

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tom 31

8

Age-dependent influence of prenatal stress on the catecholamine level in adrenals and blood glucose concentration in immobilized rats

84%

Beszczynska B., Siejka A.

Acta Biologica Cracoviensia. Series Zoologia

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2008

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tom 50

43-48

9

Influence of fasting on adrenal medullary reaction to diazepam

84%

Beszczynska B.

Acta Biologica Cracoviensia. Series Zoologia

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2003

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tom 45

10

Mechanisms of catecholamine secretion from chromaffin cells

84%

Burgoyne R. D.

Journal of Physiology and Pharmacology

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1995

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tom 46

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nr 3

11

Changes of cellular cAMP level in Tetrahymena during starvation and conjugation

84%

Yu Y. H., Xiang X., Wu D., Chen Y.

Acta Protozoologica

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1993

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tom 32

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nr 2

12

Influence of diazoxide on the function of mitochondria in guinea pig liver under myocardium dystrophy

84%

Kurhalyuk N., Tkachenko G.

Bulletin of the Veterinary Institute in Puławy

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2006

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tom 50

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nr 1

13

Early effects of short-term endurance training on hormonal responses to graded exercise

84%

Chwalbinska-Moneta J., Kruk B., Nazar K., Krzeminski K., Kaciuba-Uscilko H., Ziemba A.

Journal of Physiology and Pharmacology

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2005

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tom 56

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nr 1

Twelve male, sedentary volunteers (22.0 ± 0.7 yrs) were submitted to three weeks of a bicycle ergometer training, consisting of 45 min exercise (at 70% VO2max), 4 times in the first week and 3 times in the next 2 weeks. They performed four incremental exercise tests with the power output increased by 50 W every 3 min until volitional exhaustion: two before training (C1 and C2), and after one (T1) and three (T3) weeks of training. Before and after each load the plasma noradrenaline (NA), adrenaline (A) and blood lactate (LA) concentrations were determined in venous blood samples as well as plasma growth hormone (HGH) and cortisol concentrations before and at the end of exercise. A decrease in NA concentration was found already after 1 week of training at power output of 100 W (p<0.01) and 200 W (p<0.05). Similar decline was maintained after 3 weeks of training. No significant training-induced differences in plasma A concentration were found, however, the thresholds for both catecholamines were significantly shifted towards higher values after 3 weeks of training. One week of training caused a decrease in the pre-exercise (p<0.01), as well as post-exercise (p<0.05) plasma cortisol and HGH concentrations. It was concluded that endurance training induced a decrease in HGH, cortisol and NA concentration already after one week of training. A decline of pre-exercise plasma HGH and cortisol levels with time of experiment may, in part, indicate familiarization to exercise protocol.

14

Noradrenaline - and glutamate - induced taurine release from bulk isolated adult rat astrocytes

84%

Puka M., Albrecht J., Lazarewicz J. W.

Acta Neurobiologiae Experimentalis

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1992

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tom 52

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nr 1

15

Relationship between EMG, blood lactate, and plasma catecholamine thresholds during graded exercise in men

84%

Chwalbinska-Moneta J., Kaciuba-Uscilko H., Krysztofiak H., Ziemba A., Krzeminski K., Kruk B., Nazar K.

Journal of Physiology and Pharmacology

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1998

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tom 49

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nr 3

16

Pharmacological analysis of sticky locomotion of terrestrial snails

67%

Kaczorowski P., Tyrakowski T., Pawlowicz W., Ziolkowski M., Kopczynska E., Lampka M., Holynska-Iwan I., Piskorska E., Stevesandt M.

Folia Malacologica

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2012

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tom 20

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nr 1

17

Catecholaminergic regulation of the hypothalamic-pituitary-adrenocortical activity

67%

Bugajski J., Turon M., Gadek-Michalska A., Borycz J. A.

Journal of Physiology and Pharmacology

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1991

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tom 42

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nr 1

The significance and site of adrenergic receptors involved in the control of the hypothalamic-pituitary-adrenal axis (HPA) activity was assessed indirectly by estimation of serum corticosterone levels 1 h after drug administration to conscious rats. Adrenergic drugs were given intracerebroventricularly (icv) and intraperito neally (ip), the antagonists 15 min prior to the agonists. Noradrenaline, adrenalin and isoproterenol given by either route increased dosedependently the serum corticosterone levels. The corticosterone response to icv noradrenaline was almost abolished by icv pretreatment with propranolol, a ß-adrenergic antagonist, and yohimbine, an α₂ -receptor blocker, and was also considerably reduced by prazosin, an α₂- adrenergic antagonist. When given ip, these antagonists did not significantly influence the noradrenaline induced corticosterone response, which suggests a suprapituitary site of action of noradrenaline in stimulation of the HPA. The corticosterone response to icv adrenalin was suppressed by prazosin given by either route. The corticosterone response to ip adrenalin was almost abolished by pretreatment with yohimbine, and also significantly diminished by propranolol given by the same route. The increase in corticosterone secretion, induced by isoproterenol given by either route, was abolished by ip injection of propranolol. These results indicate that noradrenaline stimulates the HPA via α and ß-adrenergic receptors, mainly at the suprapituitary level. Adrenalin increases that activity both via central and pituitary a and ß-adrenoceptors. Isoproterenol activates the HPA by stimulation of pituitary ß-receptors.

18

Napoleon Cybulski - Polish pioneer in developing of the device for measuring blood flow velocity

67%

Pawlik W. W., Konturek S. J., Bilski R.

Journal of Physiology and Pharmacology. Supplement

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2006

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tom 57

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nr 1

107-118

Napoleon Cybulski (1854-1919) was the most prominent Polish physiologist who chaired the Department of Physiology at the Faculty of Medicine of Jagiellonian University between 1885 and 1919. One of his greatest achievements was the construction of a device for precise measurements of blood movement in the vessels - the photohemotachometer, which provided a better insight into the physiology and pathophysiology of the circulatory system. In the field of endocrinology Cybulski together with Szymonowicz, found out that adrenal extracts contain biologically active substances that elevate blood pressure. He was also a constructor of an extremely clever microcalorimeter to measure the quantity of heat produced during isolated muscle contraction. He applied, for the first time, condensator discharges to stimulate nerves and analyzed changes in the excitability of the muscles. Cybulski proved that the cause of the electrical excitability of tissue depends on the electrical energy and the time of its duration. Together with Beck, he performed the experiments on the sensory centers in the central nervous system by means of the observations of the electrical evoked potentials. They discovered the continuous electrical oscillations in the brain - the brain waves and recorded the negative electrical potentials in certain brain areas induced by sensory impulses coming from the periphery. Using this technique Beck and Cybulski localized various centers in the brain of dogs and Macaccus rhesus monkeys. The names of Beck and Cybulski were quoted in many publications on neurophysiology and electroencephalography. The present paper describes Napoleon Cybulski as a constructer of an original instrument for studying the movement of blood under various experimental conditions an emphasizes the contribution of this invention to the development of physiology.

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Influences of menstrual cycle phases on sympatho-adrenal activity and mental work performance level in healthy women

67%

Bargiel Z., Wasilewska E., Swiecka E., Beszczynska B.

Acta Universitatis Nicolai Copernici. Biologia

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1997

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tom 52[96A]

20

In vitro effects of hormones as a potential chemoattractant of mammalian spermatozoa

67%

Sliwa L.

Acta Biologica Cracoviensia. Series Botanica et Zoologia. Supplement

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1997

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tom 39

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nr 1

Ograniczanie wyników

Prolonged hyperadrenalinemia impairs exercise ability in rats

Adrenal hormones and the regulation of acute phase protein synthesis

Histological and histochemical study of the magnocellular neuroendocrine system in white rat after parenteral administration of adrenaline

Effect of adrenalin, insulin and contractions on the content of the free fatty acid fraction in skeletal muscle

Reverse 3,3',5'-triiodothyronine influences the hyperglycaemia in chickens induced by dexamethasone and exogenous glucose; Lack of effect on hyperglycaemia elicited by adrenaline

Relation of adrenergic receptors, which have roles in gastroprotective and anti-inflammatory effect of adrenal gland hormones, with cyclooxygenase enzyme levels in rats

Neurosecretory and histological changes in hypothalamus and neural zone of pituitary gland in rats following hydrocortisone and adrenaline administration

Age-dependent influence of prenatal stress on the catecholamine level in adrenals and blood glucose concentration in immobilized rats

Influence of fasting on adrenal medullary reaction to diazepam

Mechanisms of catecholamine secretion from chromaffin cells

Changes of cellular cAMP level in Tetrahymena during starvation and conjugation

Influence of diazoxide on the function of mitochondria in guinea pig liver under myocardium dystrophy

Early effects of short-term endurance training on hormonal responses to graded exercise

Noradrenaline - and glutamate - induced taurine release from bulk isolated adult rat astrocytes

Relationship between EMG, blood lactate, and plasma catecholamine thresholds during graded exercise in men

Pharmacological analysis of sticky locomotion of terrestrial snails

Catecholaminergic regulation of the hypothalamic-pituitary-adrenocortical activity

Napoleon Cybulski - Polish pioneer in developing of the device for measuring blood flow velocity

Influences of menstrual cycle phases on sympatho-adrenal activity and mental work performance level in healthy women

In vitro effects of hormones as a potential chemoattractant of mammalian spermatozoa