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1

Workaholism - affliction, addiction or way of life

100%
Gromadecka-Sutkiewicz M., Krzywinska-Wiewiorowska M.
Polish Journal of Environmental Studies
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2004
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tom 13
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nr Suppl.2, Part 1
Work is one of the most important activities for people in modern society. The blurred border between leisure and work, linked with the changes in the character of work has led to the birth of a new type of pathology. The aim of this article is a better knowledge and understanding of the phenomenon of workaholism. The term "workaholism" is widely used but there is very little consensus as to its meaning. The present study reviews different studies and opinions on workaholism and ways of dealing with this problem.
2
Content available remote

Attitude toward alcoholics and their families

100%
Sulek J., Korczak-Dziurdzik A., Korbel-Pawlas M., Lyznicka M., Czarnecki D.
Journal of Physiology and Pharmacology. Supplement
|
2006
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tom 57
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nr 4
349-358
The objective of this work was to find out whether alcoholics undergoing therapy are considered rightful members of society. We also examined the attitudes of society toward the alcoholic’s family. Alcoholism is a specific disorder. Alcohol-addicted persons deny their illness and often engage their closest surrounding in the denial system. They also find in the society a specific margin of consent to drink. Research shows that treated alcoholics believe the society has a low level of knowledge concerning alcohol addiction. They fear the perspective of going back to work or finding a new job after finishing therapy. Studies done among the inhabitants of the mountainous Podhale Region in Poland show that a high percentage of people are convinced that one should be ashamed of being an alcoholic and many would feel awkward in the presence of a sober alcoholic. The people declare that they would not trust a person being treated because of the addiction and name professions that alcoholics should not work in. The spouse of an alcoholic is often blamed for the addiction, and children of alcoholics are perceived as people with worse life perspectives than their peers.
3

The cannabinoid system in brain reward and addiction

84%
Molleman A., Hasenoehrl R.
Acta Neurobiologiae Experimentalis
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2005
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tom 65
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nr 5
4

Emission of 50‑kHz ultrasonic vocalizations in dopamine-denervated rats treated with amphetamine: relevance to neurocircuitries involved in drug-mediated reward

84%
Costa G., Marongiu J., Morelli M., Simola N.
Acta Neurobiologiae Experimentalis
|
2019
|
tom 79
|
nr Suppl.1
Rats emit 50-kHz ultrasonic vocalizations (USVs) in response to pleasurable stimuli, and USVs are increasingly being used to investigate the affective properties of drugs. Dopamine in the shell of the nucleus accumbens is instrumental in the emission of 50-kHz USVs, but little is known about how calling behavior is modulated by other brain regions that receive dopaminergic innervation. To clarify this issue, we evaluated calling behavior stimulated by repeated amphetamine administration in rats subjected to either bilateral or unilateral dopaminergic denervation with 6‑OHDA in the medial prefrontal cortex (mPFC), dorsolateral striatum (DLS), or medial forebrain bundle (MFB). Dopaminergic denervation in the PFC, DLS, or MFB only partially attenuated the development of 50-kHz USVs sensitization during repeated treatment with amphetamine. However, rats bearing a dopaminergic denervation in the mPFC emitted a low number of conditioned USVs upon re-exposure to the amphetamine-paired environment. Sensitization in ultrasonic calling and emission of 50-kHz USVs conditioned to an environment previously paired with drug administration have recently emerged as behavioral correlates of the motivational properties of drugs of abuse. Accordingly, the present results may provide new insight into the neurocircuitries involved in reward and motivation mediated by addictive drugs.
5
Content available remote

Tobacco smoking behavior among high school students in Poland

84%
Kuznar-Kaminska B., Brajer B., Batura-Gabryel H., Kaminski J.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
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nr 6
393-399
6

"Estetoreksja" - nowy rodzaj uzależnienia

84%
Pikura A.
Kosmetologia Estetyczna
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2015
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tom 04
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nr 2
7

Drug addiction as drive satisfaction [antidrive] dysfunction

84%
Kostowski W.
Acta Neurobiologiae Experimentalis
|
2002
|
tom 62
|
nr 2
8

Ocena zwyczajow zywieniowych mlodych mezczyzn uzaleznionych od srodkow psychoaktywnych

67%
Wlodarek D., Leszczynska B., Oczkowski M., Gromadzka-Ostrowska J.
Bromatologia i Chemia Toksykologiczna
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2008
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tom 41
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nr 3
921-925
9

Addictions among students of the Medical University of Bialystok in the years 2000-2003 - a cohort study

67%
Czapska D., Ostrowska L., Stefanska E., Karczewski J.
Polish Journal of Environmental Studies
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2004
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tom 13
|
nr Suppl.2, Part 1
The aim of the study was to assess addictions among students in the years 2000-2003. One hundred and thirty students were recruited for questionnaire investigations in the year 2000, 128 and 121 participated in the subsequent years. The age range was 19-23 years. In the study period, a slight increase was observed in the percentage of cigarette smoking among male and female students. Alcohol consumption showed a slightly growing tendency in women. A rise was found in the percentage of both men and women drinking tea and of men drinking coffee. The students involved in the study were neither psychoactive drug- nor pharmaceutic-addicts.
10

Metabolizm nikotyny

67%
Tyrpien K.
Bromatologia i Chemia Toksykologiczna
|
2002
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tom 35
|
nr 1
17-25
11

Pracoholizm jako problem spoleczny

67%
Plucinska K.
Problemy Jakości
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2003
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tom 35
|
nr 06
43
12
Content available remote

Systemically active human opiorphin is a potent yet non-addictive analgesic without drug tolerance effects

67%
Rougeot C., Robert F., Menz L., Bisson J.-F., Messaoudi M.
Journal of Physiology and Pharmacology
|
2010
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tom 61
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nr 4
483-490
Human opiorphin QRFSR-peptide protects enkephalins from degradation by human neutral endopeptidase (hNEP) and aminopeptidase-N (hAP-N) and inhibits pain perception in a behavioral model of mechanical acute pain (1). Here, using two other pain rat models, the tail-flick and the formalin tests, we assess the potency and duration of the antinociceptive action of opiorphin with reference to morphine. The occurrence of adverse effects with emphasis on the side-effect profile at equi-analgesic doses was compared. We demonstrate that opiorphin elicits minimal adverse morphine-associated effects, at doses (1-2 mg/kg, i.v.) that produce a comparable analgesic potency in both spinally controlled thermal-induced acute and peripheral chemical-induced tonic nociception. The analgesic response induced by opiorphin in the formalin-induced pain model preferentially requires activation of endogenous µ-opioid pathways. However, in contrast to exogenous µ-opioid agonists such as morphine, opiorphin, does not develop significant abuse liability or antinociceptive drug tolerance after subchronic treatment. In addition, anti-peristaltism was not observed. We conclude that opiorphin, by inhibiting the destruction of endogenous enkephalins, which are released according to the painful stimulus, activates restricted opioid pathways specifically involved in pain control, thus contributing to a greater balance between analgesia and side-effects than found with morphine. Therefore, opiorphin could give rise to new analgesics endowed with potencies similar to morphine but with fewer adverse effects than opioid agonists. Its chemical optimization, to generate functional derivatives endowed with better bioavailability properties than the native peptide, could lead to a potent class of physiological type analgesics.
13

Analysis of connection between giving up smoking and demographic factors, subjective health ailments and grade of nicotine addiction in Polish high school students

67%
Darocha T., Skoczylas P., Smolen A., Gozdziuk K.
Polish Journal of Environmental Studies
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2004
|
tom 13
|
nr Suppl.2, Part 1
Analysis of the connection between giving up smoking and demographic factors, subjective health ailments and the grade of nicotine addiction according to Fageström. The anonymous survey study assumed 25 247 students, aged 15-19 years old. The respondents came from 75 towns, randomly selected from 16 provinces. The following statistic procedures have been used to identify the factors that influence the giving up smoking process by Polish high school students: test of homogeneity chi-square, Pareto analysis and multivariate discriminatory analysis. Conclusions: High grade of nicotine addiction according to Fageström was noticed despite young age. Discriminatory model allows precise prediction of giving up smoking. Cough, lowered effort tolerance and chest pain were the most frequently mentioned health ailments.
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