Wyniki wyszukiwania - AGRO

1

Absorption of nitrogen oxide of low concentrations into aqueous solutions of Na2SO3 and Fe[II]edta with added N2H4

100%

Suchecki T. T., Kumazawa H.

Archiwum Ochrony Środowiska

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1998

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tom 24

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nr 4

2

The effects of cadmium on glucose and L-ascorbic acid absorption and glucose accumulation in rat intestines

86%

Dolezych B., Dolezych S., Szmatloch A., Mekail A., Jethon Z., Fiala A.

Acta Biologica Silesiana

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1990

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tom 15

3

Quantitative estimation of small intestine alkaline phosphatase activity during the process of lipid absorption

86%

Gawlik Z., Wisniewska E.

Folia Histochemica et Cytobiologica

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1984

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tom 22

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nr 3-4

4

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Estimation of I131 doses absorbed by the thyroid in the period from May to June 1986

86%

Chas J., Baltrukiewicz Z.

Acta Physiologica Polonica

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1987

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tom 38

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nr 4

5

Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans

86%

Walkowiak J., Bajerska J., Kargulewicz A., Lisowska A., Siedlerski G., Szczapa T., Kobelska-Dubiel N., Grzymislawski M.

Acta Biochimica Polonica

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2013

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tom 60

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nr 3

Background & Aims: Green tea is known worldwide for its high content of polyphenolic compounds and multifactorial beneficial effects on human health. The role of green tea as an inhibitor of lipid hydrolysis is widely discussed. The aim of the study was to assess the influence of green tea extract on lipid digestion and absorption. Methods: The study comprised 32 healthy volunteers aged 23 to 30 years with normal exocrine pancreatic function. In all subjects 13C-labelled mixed triglyceride breath test was performed twice with and without green tea extract ingestion. Cumulative percentage dose recovery was considered to reflect digestion and absorption of lipids. Values are expressed as medians and 1st-3rd quartile distribution. Results: In all subjects, cumulative percentage dose recovery values were normal in a placebo test (36.8% <30.1-43.3%>). These results were significantly higher (p=0.021) than those obtained in green tea extract test (28.8% <23.1-37.2%>). Results of six tests with GTE were abnormal. Conclusions: Single dose of green tea extract taken with a test meal decreases lipid digestion and absorption in humans.

6

Spectroscopic studies of naproxen and tryptophan immobilized in polyvinyl alcohol

86%

Sabara D.M. D. M., Dunne J.S. J. S., Pedro A.Q.H. A. Q. H., Trifunovic J. J., Balogun I.I.O. I. I. O., Kotlicic O. O., Serrano A. A., Kertesz I. I.

Biotechnology and Food Science

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2011

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tom 75

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nr 1

7

Bioavailability of anthocyanins from red cabbage products

86%

Wiczkowski W., Topolska J., Szawara-Nowak D., Ornatowska A., Piskula M. K.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

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nr Suppl.1

8

The paradox of iron deficiency in industrialized countries and what to do about it

86%

Hallberg L.

Żywienie Człowieka i Metabolizm

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1990

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tom 17

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nr 4

Autor jest uznanym w świecie ekspertem w dziedzinie metabolizmu żelaza w organizmie człowieka. W artykule wykorzystując szeroko wyniki własnych prac badawczych przedstawił pogląd na przyczyny częstego występowania niedoborów tego pierwiastka w populacjach krajów uprzemysłowionych, a ponadto zaproponował metody profilaktyki. Pierwsza część artykułu dotyczy aktualnego stanu wiedzy na temat zapotrzebowania człowieka na żelazo w zależności od wieku, płci i stanów fizjologicznych (tabela 1). Następnie omówiono czynniki pokarmowe nasilające i hamujące wchłanianie żelaza. Do tych pierwszych należą kwas askorbinowy, mięso, ryby, produkty żywnościowe pochodzenia morskiego; natomiast do tych drugich fityniany, taniny, wapń. Z kolei przedstawiony został problem przyswajalności żelaza z różnych posiłków. Z badań autora i wsp. wynikają kilkakrotne różnice w przyswajalności tego pierwiastka, zależnie od równowagi pomiędzy czynnikami wpływającymi dodatnio i ujemnie na ten proces. W dalszej części artykułu autor koncentruje się na częstości występowania niedoborów żelaza w niektórych krajach europejskich (tabela 3) i przyczynach jej zróżnicowania. Biorąc pod uwagę dwie możliwości tego faktu odrzuca pierwszą, tj. różnice w zapotrzebowaniu, natomiast uznaje drugą, tj. różnice w spożyciu produktów, które bądź są źródłem żelaza bądź zawierają składniki wpływające na jego wchłanianie (tabela 4). Wreszcie w końcowej części pracy został przedstawiony pogląd autora na sposoby poprawy sytuacji w zakresie stanu odżywienia żelazem (tabela 6). Jednym z nich jest poprawienie wykorzystania przez organizm dostępnego żelaza pokarmowego. Tutaj w grę wchodzi zwiększenie spożycia produktów żywnościowych nasilających wchłanianie żelaza (warzywa, owoce, mięso, ryby). Drugim sposobem jest wzrost spożycia wchłanialnego żelaza. Wśród dostępnych możliwości autor dyskutuje zwiększenie wysiłku fizycznego, co pozwoli spożywać więcej żywności, poprawę posiłków (zwiększenie „gęstości odżywczej” w odniesieniu do żelaza, m.in. poprzez ograniczenie tłuszczu i cukru), zwiększenie poziomu dodawania żelaza do żywności, stosowanie lepszych związków żelaza do fortyfikacji żywności.

9

Evaluation of solid dispersions containing magnesium levulinate salts with selected carriers

86%

Marcoin W., Szulc-Musiol B.

Journal of Elementology

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2011

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tom 16

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nr 4

Among the methods applied to ensure optimal pharmaceutical availability of a drug is the incorporation of solid dispersions, i.e. combinations containing a therapeutic substance and a carrier deprived of its pharmacological activity. While manufacturing solid dispersions, special attention must be paid to carriers with a polymeric structure and hydrophilic properties, e.g. polyvinylpyrrolidone (PVP) and also phosphatidylcholine (PC). The aim of this study has been to evaluate the influence of the carriers PVP and PC 45 on pharmacokinetic parameters of Mg2+ absorption from Mg(Lev)2, Mg(LevGly), Mg(LevArg) as well as from solid dispersions containing these salts. The o/w partition coefficient was determined and the log P value calculated for pure salts and for solid dispersions containing the salts during this study. The process of Mg2+ absorption was examined in vitro on a model of the rat’s small intestine. Our analysis of the results indicates that addition of PVP or PC 45 to solid dispersions (containing magnesium levulinate salts) significantly improves the degree of Mg2+ ion absorption. It has been found that addition of PVP and PC 45 to solid dispersions with magnesium levulinate salts significantly influences the rate of Mg2+ absorption from the formulations. Moreover, the results indicate that additional ligand (glycine or arginine) in the structure of magnesium levulinate triggers the effect consisting in depressed lipophilicity for these compounds. Using the PVP or PC 45 carriers for making solid dispersions containing magnesium levulinate and derivatives with glycine or arginine ligands is quite a promising solution for attaining improved pharmaceutical availability of drugs.

10

The role of the paraovarian lymphatic plexus in absorption from the peritoneal and paraovarian sac cavities in the pig

86%

Doboszynska T., Andronowska A., Sobotka A., Janiszewska L.

Polish Journal of Veterinary Sciences

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2000

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tom 03

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nr 1

The broad ligament and .'paraovarian sac tissuek in various areas of the paraovarian lymphatic plexus after administration of carbon particles and latex bieads were examined for absorption from peritoneal and sac cavities in pigs during the estrous cycle. 30 min after the introduction of carbon particles, lymphatic pathways were stained black through all phases of the estrous cycle, however, near the uterine horn, oviductal isthmus and subovarian areas of the lymphatic plexus, staining occurred within 1-2 min. SEM-study revealed that latex beads (0.8 urn in diameter) had reached the lumen of lymphatic lacunae (or large lymphangions) within 20-30 min. The latex beads penetrated through stomatal orifices, small pores or fenestrations and epithelial-free communications with connective tissue in sac walls, as well as through the macula cribriformis prelymphatic channels. Their absorption was area-dependent; being greatest in those areas where carbon particles were also greatest.

11

Removal of NO by aqueous mixed solution of ferrous chelate and sulfite with added hydrazine, communicate

86%

Suchecki T. T., Kumazawa H.

Archiwum Ochrony Środowiska

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1998

|

tom 24

|

nr 2

12

Influence of bentonite on trace element kinetics in rats. II. Calcium

86%

Grosicki A., Kowalski B., Bik D.

Bulletin of the Veterinary Institute in Puławy

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2004

|

tom 48

|

nr 3

13

An attempt to exhibit the point of absorption and the passage for transporting proteine substances in tapeworms

72%

Walski M., Hassa Z., Cielecka D.

Folia Histochemica et Cytobiologica

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1986

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tom 24

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nr 4

14

Estimation of absorption of magnesium nicotinate and its derivatives with selected amino acids

72%

Marcoin W., Szulc-Musiol B.

Journal of Elementology

|

2009

|

tom 14

|

nr 2

313-321

Preparation of solid dispersions is a popular pharmaceutical technology designed to improve the solubility and absorption characteristics of drugs. Solubilizing and moisturizing of carriers show influence on therapeutic substances; although dissolution of molecular dispersion of particles of the therapeutic substance in a neutral carrier is of utmost importance. This paper present the results of the research on influence of modification the structure of magnesium nicotinate Mg(Nic) with ligands, glycine and arginine, on the absorption process of Mg2+ions in vitro. The absorption area was the small intestine of a rat. It was found that structural changes with an additional arginine or glycine ligand affect the absorption process of Mg2+ions. Moreover, the effect of hydrophilic carriers on the partition coefficient (log P) for the system of n-octanol and phosphate buffer was investigated for the solid dispersions containing the examined magnesium salts. Phosphatidylcholine (PC-45) and polyvinylpirrolidone (PVP K-30) were used as carriers for solid dispersions with of magnesium salts. It was confirmed that using auxiliary substances PC-45 and PVP changes significantly (p<0.05) P values, corresponding to increasing hydrophobic properties of solid dispersions of the examined salts. It was found that modification of the structure of magnesium nicotinate by amino acids such as arginine or glycine positively influences the absorption process Mg2+ ions. The research carried out on properties of the solid dispersions containing magnesium salts and phospatidylcholine (PC-45) or magnesium salts and polyvinylpirrolidone (PVP K30) showed positive influence of these auxiliary substances.

15

Gastroenterological research in domestic animals - past, present and future perspectives

72%

Zabielski R., Gill J.

Journal of Physiology and Pharmacology. Supplement

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2003

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tom 54

|

nr 3

263-281

The gastrointestinal research in domestic animals in Poland is briefly discussed in the section. The history starts over seventy years ago with the creation of the Department of Animal Physiology at the Veterinary Faculty of Warsaw University. Professor B. Gutowski, the first head of the Department, and his pupils established the School of Gastrointestinal Physiology; renowned for the achievements in physiology of digestion, gastrointestinal motility, pancreas and liver functions, and comparative physiology of domestic ruminants and wild animals. After the WWII the gastrointestinal research has also been initiated in the newly established faculties of veterinary and animal science of the agricultural universities in Lublin (motility, composition of pepsinogen, biliary and pancreas secretion, vitamin and microelement absorption), Szczecin (lipid absorption, lymph formation), Wroc³aw (gastrointestinal and gall bladder motility, bile secretion) as well as in the Institute of Animal Physiology and Nutrition of the Polish Academy of Science (digestion and absorption, development of the gastrointestinal tract in neonates). The research activity was focused on solving the problems faced by animal production in Poland, but it also resulted in a considerable number of physiological findings of an international dimension, and initiated new research areas.

16

Effects of solar radiation on motility, photomovements and pigmentation in two strains of the cyanobacterium, Phormidium uncinatum

72%

Hader D.-P., Hader M.

Acta Protozoologica

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1990

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tom 29

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nr 4

17

The impact of UV mediated hydrogen peroxide on culturable bacteria in the surface microlayer of eutrophic lake

72%

Walczak M., Swiontek Brzezinska M.

Polish Journal of Ecology

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2009

|

tom 57

|

nr 3

547-554

Hydrogen peroxide (H₂O₂) formation in surface waters is initiated by the absorption of sunlight by dissolved organic matter (DOM). The fraction of the DOM pool that interacts with sunlight, referred to as chromophoric dissolved organic matter, impacts the optical properties of surface waters. Second source of H₂O₂ is wet and dry deposition of photogenerated substance in the atmosphere and biological production. The study examined the concentration of hydrogen peroxide in water from the surface microlayer (SM) (<100 m) and subsurface water (SSW) (25 cm) in the typical eutrophic (TOC 5–15 mg dm⁻³; chlorophyll 5–26 g dm⁻³, water transparency 0.6–1.0 m) lake as well as the impact of this compound on occurrence and survivorship of catalase-positive and catalase-negative bacteria isolated and cultured on the TSA medium (Difco). The experimental H₂O₂ concentrations ranged between 500–5000 nM. The concentration of H₂O₂ in analyzed water samples clearly increased in day-time hours and was different in May, July and October. The highest natural concentration of H₂O₂ (700 nM) was observed in SM water in summer in afternoon hours. During that period, 100% of bacterial populations found in SM water produced catalase. The experiments confirmed that environmental concentrations of H₂O₂ caused no considerable decrease in survivorship of culturable bacteria, while concentrations exceeding 1000 nM were lethal for the majority of catalasenegative bacteria, but not for catalase-positive bacteria.

18

A biogeochemical barrier to enhance a buffer zone for reducing diffuse phosphorus pollution - preliminary results

72%

Izydorczyk K., Fratczak W., Drobniewska A., Cichowicz E., Michalska-Hejduk D., Gross R., Zalewski M.

International Journal of Ecohydrology and Hydrobiology

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2013

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tom 13

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nr 2

19

Apical NAplus-Hplus exchangers in the mammalian gastrointestinal tract

72%

Kiela P. R., Xu H., Ghishan F. K.

Journal of Physiology and Pharmacology. Supplement

|

2006

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tom 57

|

nr 7

51-79

The Slc9a family of nine Na+/H+ exchangers (NHE) plays a critical role in neutral sodium absorption in the mammalian intestine as well as other absorptive and secretory epithelia of digestive organs. These transport proteins mediate the electroneutral exchange of Na+ and H+ and are crucial in a variety of physiological processes, including the fine tuning of intracellular pH, cell volume control and systemic electrolyte, acid-base and fluid volume homeostasis. Here, we review the role of the Na+/H+ exchange mechanism as it relates to the physiology of organs and cells involved in nutrient absorption, and we describe physiological and molecular aspects of individual isoforms, including their structure, tissue-, and subcellular distribution, as well as their regulation by physiological stimuli at the transcriptional and post-transcriptional levels. A particular emphasis is placed on Na+/H+ exchanger isoforms expressed on the apical (brush border) membrane of the epithelial cells, and the consequences of gene-targeted mutation of individual isoforms are discussed in the context of the physiology of digestive organs. Where available, we also provide a review of pathophysiological states related to aberrant expression and/or activity of Na+/H+ exchangers within the confines of the digestive system.

20

Influence of hepcidin on iron metabolism

72%

Kosla T., Skibniewska E. M.

Medycyna Weterynaryjna

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2010

|

tom 66

|

nr 05

291-293

The main role of iron is being part of haemoglobin, whose level it stabilizes; however, iron also plays a very important role in immunological processes and the metabolism of the organism. Hepcidin is a peptide hormone. It was first isolated from human blood and urine, and its release was attributed to the liver. A failure to produce hepcidin is related to iron overload, while its excessive production to anaemia caused by iron deficit. The releasing of hepcidin also affects hypoxia and inflammation through inhibiting these processes in patients with haemochromatosis. There are three forms of the regulation of the iron level: the first is a regulation in cellular storages, the second is erythropoiesis and the third is a dietary regulator. Hepcidin was identified as a regulator which communicates the level of iron reserves in the organism to intestine cells responsible for the absorption of iron. In inflammatory conditions, when the organism wishes to cause alimentary iron deficit, hepcidin production increases even a hundred fold, thus leading to anaemia. Hepcidin is also a stimulator of inflammation as an antibacterial factor produced in the liver parenchyma. It decreases the absorption of iron in the intestines and increases the secretion of iron to the reticuloendothelial system. Experiments on animals deprived of hepcidin and animals with its excess make it possible to understand iron homeostasis and confirm the role of hepcidin as a hormone regulating iron metabolism.

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