Wyniki wyszukiwania

1

Targeting Th17 effector cytokines for the treatment of autoimmune diseases

100%

Yamagata T., Skepner J., Yang J.

Archivum Immunologiae et Therapiae Experimentalis

|

2015

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tom 63

|

nr 6

2

Human T regulatory cells: on the way to cognition

86%

Kaczorowski M., Jutel M.

Archivum Immunologiae et Therapiae Experimentalis

|

2013

|

tom 61

|

nr 3

3

Type I interferons as immunoregulatory molecules; implications for therapy in experimental autoimmune uveoretinitis

86%

Mizuguchi J., Takeuchi M., Usui M.

Archivum Immunologiae et Therapiae Experimentalis

|

2002

|

tom 50

|

nr 4

4

Lower expression of mRNA for interferon-gamma in T helper cells of children with newly diagnosed lymphomas

86%

Luczynski W., Kovalchuk O., Krawczuk-Rybak M., Mitura-Lesiuk M., Malinowska I., Chyczewski L., Kowalczyk J., Matysiak M.

Folia Histochemica et Cytobiologica

|

2005

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tom 43

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nr 3

5

Nitric oxide and superoxide in inflammation and immune regulation

86%

Guzik T. J., Korbut R., Adamek-Guzik T.

Journal of Physiology and Pharmacology

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2003

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tom 54

|

nr 4

Nitric oxide (NO) and reactive oxygen species exert multiple modulating effects on inflammation and play a key role in the regulation of immune responses. They affect virtually every step of the development of inflammation. Low concentrations of nitric oxide produced by constitutive and neuronal nitric oxide synthases inhibit adhesion molecule expression, cytokine and chemokine synthesis and leukocyte adhesion and transmigration. Large amounts of NO, generated primarily by iNOS can be toxic and pro-inflammatory. Actions of nitric oxide are however not dependent primarily on the enzymatic source, but rather on the cellular context, NO concentration (dependent on the distance from NO source) and initial priming of immune cells. These observations may explain difficulties in determining the exact role of NO in Th1 and Th2 lymphocyte balance in normal immune responses and in allergic disease. Similarly superoxide anion produced by NAD(P)H oxidases present in all cell types participating in inflammation (leukocytes, endothelial and other vascular cells etc) may lead to toxic effects, when produced at high levels during oxidative burst, but may also modulate inflammation in a far more discrete way, when continuously produced at low levels by NOXs (non-phagocytic oxidases). The effects of both nitric oxide and superoxide in immune regulation are exerted through multiple mechanisms, which include interaction with cell signalling systems like cGMP, cAMP, G-protein, JAK/STAT or MAPK dependent signal transduction pathways. They may also lead to modification of transcription factors activity and in this way modulate the expression of multiple other mediators of inflammation. Moreover genetic polymorphisms exist within genes encoding enzymes producing both NO and superoxide. The potential role of these polymorphisms in inflammation and susceptibility to infection is discussed. Along with studies showing increasing role of NO and free radicals in mediating inflammatory responses drugs which interfere with these systems are being introduced in the treatment of inflammation. These include statins, angiotensin receptor blockers, NAD(P)H oxidase inhibitors, NO-aspirin and others. In conclusion in this mini-review we discuss the mechanisms of nitric oxide and superoxide dependent modulation of inflammatory reactions in experimental animals and humans. We also discuss potential roles of nitric oxide as a mediator of allergic inflammation.

6

Gene polymorphisms of novel immunotolerant molecule BTLA: distribution of alleles, genotypes and haplotypes in Polish Caucasian population

72%

Partyka A., Woszczyk D., Strzala T., Szczepanska A., Tomkiewicz A., Frydecka I., Karabon L.

Archivum Immunologiae et Therapiae Experimentalis

|

2015

|

tom 63

|

nr 1

7

Allergen-associated immunomodulators: modifying allergy outcome

72%

Gomez-Casado C., Diaz-Perales A.

Archivum Immunologiae et Therapiae Experimentalis

|

2016

|

tom 64

|

nr 5

8

Curcumin improves experimentally induced colitis in mice by regulating follicular helper T cells and follicular regulatory T cells by inhibiting interleukin-21

72%

Li S.-Q., Lv X.-D., Liu G.-F., Gu G.-L., Chen R.-Y., Chen L., Fan J.-H., Wang H.-Q., Liang Z.-L., Jin H., Qin L.-F., Xie Y.-F., Lu F., Jiang H.-X., Zhan L.-L., Lv X.-P.

Journal of Physiology and Pharmacology

|

2021

|

tom 72

|

nr 1

9

Allergen-specific T cells in IgE-mediated food allergy

72%

Saidova A., Hershkop A. M., Ponce M., Eiwegger T.

Archivum Immunologiae et Therapiae Experimentalis

|

2018

|

tom 66

|

nr 3

10

Pattern recognition receptors: significance of expression in the liver

72%

Zeromski J., Kierepa A., Brzezicha B., Kowala-Piaskowska A., Mozer-Lisewska I.

Archivum Immunologiae et Therapiae Experimentalis

|

2020

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tom 68

|

nr 5

11

Helper T-cell differentiation in graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

72%

Fu J., Heinrichs J., Yu X.-Z.

Archivum Immunologiae et Therapiae Experimentalis

|

2014

|

tom 62

|

nr 4

12

Involvement of microRNAs in the inflammatory pathways of pulmonary sarcoidosis

72%

Bak M., Jazwa A., Kasper L., Kachamakova-Trojanowska N., Jozkowicz A., Skladek K., Dulak J.

Journal of Physiology and Pharmacology

|

2015

|

tom 66

|

nr 5

13

Differentiation of T cells into helper cells from immature precursors: identification of a target cell for a proline-rich polypeptide (PRP)

72%

Wieczorek Z., Zimecki M., Spiegel K., Lisowski J., Janusz M.

Archivum Immunologiae et Therapiae Experimentalis

|

1989

|

tom 37

|

nr 3-4

14

Fundamental immunology of skin transplantation and key strategies for tolerance induction

72%

Zhou J., He W., Luo G., Wu J.

Archivum Immunologiae et Therapiae Experimentalis

|

2013

|

tom 61

|

nr 5

15

Allergen-specific T lymphocytes as targets for specific immunotherapy: striking at the roots of type I allergy

72%

Bohle B.

Archivum Immunologiae et Therapiae Experimentalis

|

2002

|

tom 50

|

nr 4

16

The impact of research on parasites beyond parasitology

72%

Kohler P.

Acta Parasitologica

|

2001

|

tom 46

|

nr 1

17

Effect of trichostatin A on CD4 surface density in peripheral blood T cells

72%

Kozlowska A., Jagodzinski P. P.

Folia Histochemica et Cytobiologica

|

2006

|

tom 44

|

nr 4

18

Decreased serum level of IL-12 in the course of ischemia and reperfusion during abdominal aortic surgery

58%

Jedynak M., Mroczko B., Siemiatkowski A., Gacko M., Szmitkowski M.

Folia Histochemica et Cytobiologica

|

2011

|

tom 49

|

nr 3

19

Fc receptor-targeted mucosal vaccination as a novel strategy for the generation of enhanced immunity against mucosal and non-mucosal pathogens

58%

Gosselin E. J., Bitsaktsis C., Li Y., Iglesias B. V.

Archivum Immunologiae et Therapiae Experimentalis

|

2009

|

tom 57

|

nr 5

311-323

20

The expression profile of Fc receptor-like Y in B lymphocytes with hepatitis B virus induced diseases

58%

Wang K., Yang R.-L., Pei H., Wu H.-Y., Zhang J., Huang B.

Folia Histochemica et Cytobiologica

|

2011

|

tom 49

|

nr 3

Ograniczanie wyników

Targeting Th17 effector cytokines for the treatment of autoimmune diseases

Human T regulatory cells: on the way to cognition

Type I interferons as immunoregulatory molecules; implications for therapy in experimental autoimmune uveoretinitis

Lower expression of mRNA for interferon-gamma in T helper cells of children with newly diagnosed lymphomas

Nitric oxide and superoxide in inflammation and immune regulation

Gene polymorphisms of novel immunotolerant molecule BTLA: distribution of alleles, genotypes and haplotypes in Polish Caucasian population

Allergen-associated immunomodulators: modifying allergy outcome

Curcumin improves experimentally induced colitis in mice by regulating follicular helper T cells and follicular regulatory T cells by inhibiting interleukin-21

Allergen-specific T cells in IgE-mediated food allergy

Pattern recognition receptors: significance of expression in the liver

Helper T-cell differentiation in graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Involvement of microRNAs in the inflammatory pathways of pulmonary sarcoidosis

Differentiation of T cells into helper cells from immature precursors: identification of a target cell for a proline-rich polypeptide (PRP)

Fundamental immunology of skin transplantation and key strategies for tolerance induction

Allergen-specific T lymphocytes as targets for specific immunotherapy: striking at the roots of type I allergy

The impact of research on parasites beyond parasitology

Effect of trichostatin A on CD4 surface density in peripheral blood T cells

Decreased serum level of IL-12 in the course of ischemia and reperfusion during abdominal aortic surgery

Fc receptor-targeted mucosal vaccination as a novel strategy for the generation of enhanced immunity against mucosal and non-mucosal pathogens

The expression profile of Fc receptor-like Y in B lymphocytes with hepatitis B virus induced diseases