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1

Mycobacterium genavense - grozny patogen ssakow i ptakow

100%
Ledwon A., Szeleszczuk P.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 06
638-642
The problem of infections with bacilli from the genus Mycobacterium is a still current issue both for human and animal pathology. The progress that has been made in mycobacteriology has brought about the discovery of many new Mycobacterium species of lower or higher pathogenicity for vertebrates. Mycobacterium genavense was discovered in 1992 in Germany. It was isolated for the first time from patients infected with HIV, who, due to a significantly impaired immune system, are particularly exposed to infections with acid-fast bacilli. Most frequently, however, M. genavense infections are found in birds. For them the bacillus is among the main causative agents of mycobacteriosis, ranking in the second place after Mycobacterium avium. Such a late discovery of this bacilli must have resulted from the fact that its isolation in artificial media is very difficult. In relation to the above the bacilli is suspected of being responsible for the disease cases where acid-fast bacilli were not isolated on artificial media but they were present in preparations stained by Ziehl-Nielsen method. Only the application of highly specific media and, primarily, achievements in molecular biology have enabled the diagnosis of infections caused by this bacilli.
2

Drug susceptibility of non-tuberculous strains of Mycobacterium isolated from birds from Poland

100%
Ledwon A., Napiorkowska A., Augustynowicz-Kopec E., Szeleszczuk P.
Polish Journal of Microbiology
|
2018
|
tom 67
|
nr 4
Mycobacterioses are a constant problem in backyard poultry, as well as pet birds. To date, no evidence of direct transmission of atypical bacilli between humans has been demonstrated, but it cannot be ruled out that sick animals can be a source of infection for people in their environment. The aim of the study was to identify mycobacteria isolated from birds with diagnosed mycobacteriosis and to determine the susceptibility of mycobacterial isolates from these animals to antituberculous drugs most commonly used in the treatment of mycobacterial infections in humans. For drug susceptibility tests, drugs such as isoniazid, rifampicin, streptomycin, ethambutol, ofloxacin, capreomycin, cycloserine and ethionamide were used. A high degree of drug resistance was demonstrated, particularly in Mycobacterium avium. Isolates of Mycobacterium xenopi showed a relatively good susceptibility to the drugs tested. The drug resistance of Mycobacterium genavense has not been determined, but this mycobacterium was identified in ten cases, which is the second most frequent occurrence in the cases studied.
3

Mycobacteriosis caused by Mycobacterium genavense in lineolated parakeets [Bolborhynchus lineola]. A case report

80%
Ledwon A., Szeleszczuk P., Malicka E., Dolka I., Zwolska Z., Augustynowicz-Kopec E., Zabost A.
Bulletin of the Veterinary Institute in Puławy
|
2009
|
tom 53
|
nr 2
209-212
Systemic mycobacteriosis caused by Mycobacterium genavense was diagnosed in a 7-year-old captive lineolated parakeet (Bolborhynchus lineola). About a year before death, proventricular dilatation syndrome (PDS) was suggested, because of persistent regurgitations and intermittent diarrhoea. Necropsy examination did not show any signs typical of PDS and mycobacterioses. No caseous necrosis, but focal ulcerated overgrowth in the proventriculus, hypertrophy of intestinal mucosa and splenomegaly, was found. Primary neoplasia was suspected. The crucial examination was histopathology, which revealed changes typical of mycobacteriosis and the presence of numerous acid-fast bacilli. A real- time SYBR® Green PCR test was used and Mycobacterium genavense infection was diagnosed. The mycobacterium was also cultured on BD BACTEC™ 460TB 12B Middlebrook 7H12 medium.
4
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Etiologia zapaleń spojówek u ptaków domowych

61%
Malek-Sanigorska A., Ledwon A.
Życie Weterynaryjne
|
2014
|
tom 89
|
nr 03
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