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1

New SNPs in the coding and 5' flanking regions of porcine MYOD1 [MYF3] and MYF5 genes

100%
Urbanski P., Kuryl J.
Journal of Applied Genetics
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2004
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tom 45
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nr 3
2

Interaction of ESR1 gene with the FSHB and MYOG genes: effect on the reproduction and growth in pigs

80%
Humpolicek P., Tvrdon Z., Urban T.
Animal Science Papers and Reports
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2009
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tom 27
|
nr 2
105-113
The study aimed at determining whether the combination of three selected genes can be used for selection in small populations of pigs. The estrogen receptor (ESR1), follicle stimulating hormone (FSHB) and porcine myogenin (MYOG) genes were selected to detect their combined effect. Although over the last decades considerable progress in pig production was achieved, reproduction in his species still remains unsatisfactory. The marker-assisted selection (MAS) is considered to bring progress in pig reproduction. If MAS is to be used efficiently, the complexity of reproduction process should be taken into consideration. The effects were studied of interaction between the mentioned three genes and selected production and reproduction traits of pigs. Interactions between the effects of particular gene markers are important because of possible negative effect(s) of a single-path selection as well as possible co-selection. No significant interaction between the effects of genes studied was found. It is concluded that in small populations co-selection is effective only when highly significant effects of selected auxiliary genes occur.
3

Variabilita genetickych markeru u prasat v CR a Polsku

80%
Dvorak J., Vrtkova I., Jasek S., Czarnecki R.
Zeszyty Naukowe. Przegląd Hodowlany
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1999
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tom 40
4

Polymorphisms in coding and regulatory regions of the porcine MYF6 and MYOG genes and expression of the MYF6 gene in m. longissimus dorsi versus productive traits in pigs

80%
Wyszynska-Koko J., Pierzchala M., Flisikowski K., Kamyczek M., Rozycki M., Kuryl J.
Journal of Applied Genetics
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2006
|
tom 47
|
nr 2
MYOG and MYF6 belong to the MyoD gene family. They code for the bHLH transcription factors playing a key role in later stages of myogenesis: differentiation and maturation of myotubes. Three SNPs in porcine MYF6 and two in porcine MYOG were analysed in order to establish associations with chosen carcass quality and growth rate traits in Polish Landrace, Polish Large White and line 990 sows. No statistically significant effect of SNP in the promoter region of the MYF6 gene on its expression measured on mRNA level was found. Associations between the genotype at the MYF6 locus and carcass quality traits appeared to be breed-dependent. The C allele in the case of SNP in the promoter region and GC haplotype in exon 1 were advantageous for right carcass side weight in Polish Landrace sows and disadvantageous for this trait in Polish Large White sows. These gene variants were also the most advantageous for loin and ham weight in sows of line 990. The mutation in exon 1 of the MYOG gene had no statistically significant association with carcass quality traits and the mutation in the 3’-flanking region had the breed-dependent effect as well. These results suggest that SNPs analysed in this study are not causative mutations, but can be considered as markers of some other, still unrevealed genetic polymorphism that influences the physiological processes and phenotypic traits considered in this study.
5

Distribution of the polymorphic variants of genes RYR1, LEP, GH, MYOG, MYF5, and GDF8 in wild boars from North-East of Poland

80%
Kuryl J., Zurkowski M., Urbanski P., Wyszynska-Koko J.
Animal Science Papers and Reports
|
2004
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tom 22
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nr 3
The aim of this study was to characterize the polymorphism of genes RYR1, LEP, GH, MYOG, MYF5 and GDF8 in wild boar population inhabiting North-East of Poland. The above genes are considered candidate genes for carcass quality traits in domestic pigs. Ninety animals were tested. Genes RYR1, LEP and MYF5 appeared to be monomorphic, whereas genes MYOG, GH and GDF8 showed polymorphism similar to that observed in European pig breeds. However, no PCR product was obtained for several animals when MYOG and GDF8 gene fragments were amplified, suggesting the difference between wild boars tested and domestic pig in sequence of the gene regions where primers annealed. Moreover,this suggests a possibility of identification of new variants of these genes in wild boar.
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