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  1. 6 Acta Parasitologica

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  1. 2 Chen D.-L.

  2. 2 Chen J.-P.

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  4. 2 Sapierzynski R.

  5. 1 Aghazadeh-Dibavar S.

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  1. 1 2021

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1

HRM–PCR is an accurate and sensitive technique for the diagnosis of cutaneous leishmaniasis as compared with conventional PCR

100%
Asfaram S., Fakhar M., Mirani N., Derakhshani-niya M., Valadan R., Hezarjaribi H. Z., Emadi S. N.
Acta Parasitologica
|
2020
|
tom 65
|
nr 2
2

Leucine-rich repeats in host-pathogen interactions

100%
Kedzierski L., Montgomery J., Curtis J., Handman E.
Archivum Immunologiae et Therapiae Experimentalis
|
2004
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tom 52
|
nr 2
3

The first successful report of the in vitro life cycle of Chinese Leishmania: the in vitro conversion of Leishmania amastigotes has been raised to 94% by testing 216 culture medium compound

84%
Li J., Zheng Z.-W., Natarajan G., Chen Q.-W., Chen D.-L., Chen J.-P.
Acta Parasitologica
|
2017
|
tom 62
|
nr 1
4

Comparative assessment of induced immune responses following intramuscular immunization with fusion and cocktail of LeIF, LACK and TSA genes against cutaneous leishmaniasis in BALB/c mice

84%
Maspi N., Ghaffarifar F., Sharifi Z., Dalimi A., Dayer M. S.
Archivum Immunologiae et Therapiae Experimentalis
|
2018
|
tom 66
|
nr 1
5

Prevalence of endoparasites in urban stray dogs from Brazil diagnosed with Leishmania, with potential for human zoonoses

84%
Saldanha-Elias A. M., Silva M. A., Silva V. O., Amorim S. L. A., Coutinho A. R., Santos H. A., Giunchetti R. C., Vitor R. W. A., Geiger S. M.
Acta Parasitologica
|
2019
|
tom 64
|
nr 2
6
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The role of toll-like receptor agonists in the immunotherapy of leishmaniosis. An update and proposal for a new form of anti-leishmanial therapy

84%
Dasgupta S., Aghazadeh-Dibavar S., Bandyopadyay M.
Annals of Parasitology
|
2014
|
tom 60
|
nr 2
The use of toll-like receptor agonists in immunotherapy is a new approach in the prevention of immunosuppression during fatal Leishmania parasite infection. The objective of such immunotherapy is to activate specific cell-mediated immune responses, macrophage activation and antigen-responsive inflammation, to kill intracellular amastigotes. Toll-like receptor agonist-based treatment in immunocompetent hosts can be effective either by selective use of the agonists alone or in combination with the anti-leishmanial drug stibanate. Recent investigations suggest that toll-like receptor signal pathways constitute a possible new mode of anti-leishmanial treatment. This article describes the prospect of toll-like receptor – mediated signal pathways in the immunotherapy of cutaneous and visceral leishmaniosis, as well as post kala-azar dermal leishmaniosis (PKADL), a skin-sequel of visceral infection. Suitable synthetic agonists need to be developed for toll-like receptors to overcome immunosuppression.
7

Rodent species diversity and occurrence of Leishmania in Northeastern Iran

84%
Motevalli-Haghi S. F., Ozbaki G. M., Hosseini-Vasoukolaei N., Nikookar S. H., Dehghan O., Yazdani-Charati J., Siahsarvie R., Dehbandi R., Fazeli-Dinan M., Enayati A.
Polish Journal of Ecology
|
2021
|
tom 69
|
nr 1
8

Seroprevalence, clinical, and pathological characteristics of canine leishmaniasis in a central region of Colombia

84%
Picon V., Almario G., Rodriguez V., Garcia N. V.
Journal of Veterinary Research
|
2020
|
tom 64
|
nr 1
9

Usefulness of PCR method for detection of Leishmania in Poland

84%
Myjak P., Szulta J., de Almeida M. E., da Silva A. J., Steurer F., Lass A., Pietkiewicz H., Nahorski W. L., Goljan J., Knap J., Szostakowska B.
Polish Journal of Microbiology
|
2009
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tom 58
|
nr 3
219-222
Leishmania parasites are the etiological agents of leishmaniosis, with severe course and often fatal prognosis, and the global number of cases has increased in recent decades. The gold standards for the diagnosis of leishmaniosis are microscopic examinations and culture in vitro of the different clinical specimens. The sensitivity of these methods is insufficient. Recent development in specific and sensitive molecular methods (PCR) allows for detection as well as identification of the parasite species (subspecies). The aim of the study was to estimate the usefulness of molecular methods (PCR) for detection of Leishmania species and consequently for the implementation of such methods in routine diagnostics of leishmaniosis in Polish patients returning from endemic areas of the disease. In our investigations we used 54 known Leishmania positive DNA templates (from culture and clinical specimens) received from the CDC (Atlanta, GA, USA). Moreover, 25 samples of bone marrow, blood or other tissues obtained from 18 Polish individuals suspected of leishmaniosis were also examined. In PCR we used two pairs of primers specific to the conserved region of Leishmania kinetoplast DNA (kDNA) minicircle (13A/13B and F/R). Using these primers we obtained amplicons in all DNA templates from the CDC and in three Polish patients suspected for Leishmania infection. In one sample from among these cases we also obtained positive results with DNA isolated from a blood specimen which was previously negative in microscopic examinations.
10

Cutaneous leishmaniasis due to three Leishmania species among Syrian refugees in Sanliurfa, Southeastern Turkey

84%
Doni N. Y., Gurses G., Dikme R., Aksoy M., Zeyrek F. Y., Simsek Z., Satoskar A. R., Varikuty S., Yesilova Y.
Acta Parasitologica
|
2020
|
tom 65
|
nr 4
11

Molecular and serological investigation of infectious diseases in captive and free-range crab-eating fox (Cerdocyon thous — Linnaeus, 1776) from Northeastern Brazil

84%
Almeida J. C., Melo R. P. B., Kim P. C. P., Guerra N. R., Alves L. C., Costa D. F., Alves C. J., Porto W. J. N., Mota R. A.
Acta Parasitologica
|
2018
|
tom 63
|
nr 1
12

Canine leishmaniosis

84%
Sapierzynski R.
Polish Journal of Veterinary Sciences
|
2008
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tom 11
|
nr 2
151-158
Canine visceral leishmaniosis (CVL) is an infectious disease of zoonotic potential, caused by protozoan parasite of the genus Leishmania. Common clinical manifestations of canine visceral leishmaniosis include decrease of appetite, progressive weight loss, exercise intolerance, peripheral lymph node and spleen enlargement, chronic renal and liver disease, muscle, atrophy, polyarthritis and others. Because the Polish literature in the field contains no information on leishmaniosis in animals the recognised case of this disease is presented. Homeless mongrel, intact female dog, 3 years of age was brought to a veterinary clinic because of apathy, and generalised dermatologie lesions to perform routine examination. Because therapeutic effect of primarily recognised scabies was unsatisfactory, the skin samples from ear margins, trunk and lesion of the area of the left gluteal region for histopatologie examination were taken. Due to suspicion of leishmaniosis, fine-needle aspiration biopsy of lymph nodes, skin lesions, ocular discharge and imprint samples from skin lesion were performed, and tissue collected were examined under optical microscopy for identification of Leishmania amastigotes. To confirm cytologic diagnosis, blood samples for serological tests (enzyme-linked im- munoabsorbent assay-ELISA; indirect immunofluorescence assay test-IFAT) were taken. Based on physical examination, histopatology, cytopathology and serology, canine visceral leishmaniosis was finally diagnosed.
13
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Content available

Antiparasitic drug-design strategy as an interdisciplinary process

84%
Boczon K.
Wiadomości Parazytologiczne
|
1994
|
tom 40
|
nr 3
14

Inhibition of Leishmania growth but not of phagocytic functions of macrophages by 5-fluorouracil in vitro

84%
Becker I., Perez-Montfort R., Perez-Torres A., Vazquez-Arana S., Carrillo-Farga L., Salaiza N., Cruz B., Marquez-Monter H., Perez-Tamayo R.
Acta Protozoologica
|
1995
|
tom 34
|
nr 4
15

Live attenuated Leishmania vaccines: a potential strategic alternative

84%
Silvestre R., Cordeiro-da-Silva A., Ouaissi A.
Archivum Immunologiae et Therapiae Experimentalis
|
2008
|
tom 56
|
nr 2
16
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

American cutaneous leishmaniasis in the state of Sao Paulo, Brazil - epidemiology in transformation

84%
Neto J. P. N., Basso G., Cipoli A. P., El Kadre L.
Annals of Agricultural and Environmental Medicine
|
1998
|
tom 05
|
nr 1
17

Występowanie zawlekanych gatunków pasożytów u psów na terenie Polski

67%
Borecka A.
Magazyn Weterynaryjny
|
2011
|
tom 20
|
nr 08
18
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Leiszmanioza u psow

67%
Sapierzynski R., Wojtczak M., Sapierzynska E.
Życie Weterynaryjne
|
2008
|
tom 83
|
nr 02
113-117
19

Phylogenic analysis of Chinese Leishmania isolates based on small subunit ribosomal RNA (SSU rRNA) and 7 spliced leader RNA (7SL RNA)

67%
Guan W., Cao D.-P., Sun K., Xu J.-N., Zhang J.-R., Chen D.-L., Chen J.-P.
Acta Parasitologica
|
2012
|
tom 57
|
nr 2
The leishmaniases are zoonotic diseases caused by protozoan parasites of the genus Leishmania. Leishmaniases are still endemic in China, especially in the west and northwest froniter regions. To revalue the preliminary phylogenetic results of Chinese Leishmania isolates, we amplified partial fragment of small subunit ribosomal RNA (SSU rRNA) and 7 spliced leader RNA (7SL RNA), then tested the phylogenetic relationships among Chinese Leishmania isolates and their relatives by analyzing SSU rRNA gene sequences and 7SL RNA gene sequences. 19 SSU RNA sequences and 9 7SL RNA sequences were obtained in our study, then analyzed with 42 SSU RNA sequences and 32 7SL RNA sequences retrieved from Genbank, respectively. In the Bayesian analysis of the SSU RNA gene, the isolate MHOM/CN/93/GS7 and the isolate IPHL/CN/77/XJ771 are members of Leishmania donovani complex, while the isolate MHOM/CN/84/JS1 clustered with Leishmania tropica. The other 11 Chinese Leishmania isolates (MHOM/CN/90/WC, MCAN/CN/90/SC11, MHOM/CN/80/XJ801, MHOM/CN/85/GS4, MHOM/CN/84/SD1, MCAN/CN/86/SC7, MHOM/CN/54/#3, MHOM/CN/83/GS2, MHOM/CN/90/SC10H2, MHOM/CN/89/GS6 and MHOM/CN/ 89/GS5) form an unclassified group, defined as Leishmania sp., and the most relative species to this group is L. tarentolae. In the Bayesian analysis of the 7SL RNA gene, 9 Chinese Leishmania isolates also formed an unclassified group with L. tarentolae, including canine isolate 10, MHOM/CN/85/GS4, MHOM/CN/84/SD1, MCAN/CN/86/SC7, MHOM/CN/54/#3, MHOM/ CN/83/GS2, MHOM/CN/90/SC10H2, MHOM/CN/89/GS6 and MHOM/CN/89/GS5. We concluded that: (1) Chinese Leishmania isolates are non-monophyly group; (2) an unclassified group may exist in China, and the most relative species to this group is L. tarentolae; (3) MHOM/CN/84/JS1, which was previously assigned as L. donovani, was most genetically related to L. tropica strain MHOM/SU/74/K27.
20
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Content available

Rola dopelniacza w odpornosci na zakazenia pierwotniakami

67%
Jankowski S.
Wiadomości Parazytologiczne
|
1997
|
tom 43
|
nr 4
369-383
The scope of this work is the presentation of new theories concerning the role of complement (C) in the resistance of high organism to the infection caused by protozoa. The mechanisms protecting of Entamoeba histolytica, Leishmania spp., Trypanosoma cruzi, Toxoplasma gondii and Naegleria fowleri from the action of C are also described.
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