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1

Modulation of 5-N-alkylresorcinol hemolytic properties by divalent cations. Dependence of the effect of cations on alkylresorcinol structure

100%
Stasiuk M., Kozubek A.
Cellular and Molecular Biology Letters
|
1997
|
tom 02
|
nr 1
It was demonstrated that the process of hemolysis of erythrocytes induced by resorcinolic lipids is inhibited by divalent cations present in the incubation medium. The extent of inhibition is dependent on the nature of both type of the cation and the hemolytic agent. Lysis most susceptible to divalent cations is that induced by short (C15) and medium-chained (C19) 5-n-alkylresorcinols, which also have the highest observed hemolytic potencies. Furthermore, the protection was the stronger the stronger lytic activity was exerted by studied compound. The homologs with the longest side chain studied, although exhibiting the lowest hemolytic activity by themself, were the least susceptible to inhibition of their hemolytic activity by cations. The effect of cobalt cation has been found to be intermediate between the effect of Mn2+ and Zn2+. The most effective in protection of erythrocytes was Zn2+ which almost completely protected the cells against alkylresorcinol-induced lysis at the concentrations of 10-6 M and above.
2

Modulation of hemolytic properties of resorcinolic lipids by divalent cations

100%
Stasiuk M., Kozubek A.
Cellular and Molecular Biology Letters
|
1996
|
tom 01
|
nr 2
The effect of divalent cations in concentrations 10-9-10-3M upon the hemolysis of sheep erythrocytes induced by resorcinolic lipids was studied. It was demonstrated that the process of hemolysis is inhibited by divalent cations present in the incubation medium. The extent of inhibition is dependent on both type of the cation and hemolytic agent. In alkylresorcinol-induced hemolysis the most effective in protection of the cells were Zn2+ and Co2+ cations. Weaker protective action was observed for Cd2+ and Mn2+. Calcium ions, in all studied concentrations, were without marked effect on the level of relative hemolysis. Magnesium ions as well as Ba2+ in nanomolar concentrations were effective inhibitors of the lysis but this effect diminished at higher (millimolar) concentrations of these ions. When alkenylresorcinols were used as hemolysis-inducers no effective protection of erythrocytes by Ca2+, Ba2+ or Mg2+ was observed. Most effective in protection of cells against this amphiphile-induced lysis, similarly to their effect observed previously for various lytic agents, were cations of Zn2+, Co2+ and Cd2+. Mn2+ cations were intermediate, with respect to their protective potency.
3

Role of alkylresorcinols in colonization of wheat by Pseudomonas sp. strain 150

84%
Magnucka E. G., Pietr S. J.
Electronic Journal of Polish Agricultural Universities. Series Agronomy
|
2018
|
tom 21
|
nr 2
4

The influence of herbicides on biosynthesis of antifungal resolcinols by rye seedlings

84%
Magnucka E., Zarnowski R., Suzuki Y., Yamaguchi I., Pietr S. J., Kozubek A.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
2001
|
tom 49
|
nr 4
5

Effect of rye 5-n-alkylresorcinols on in vitro growth of phytopathogenic Fusarium and Rhizoctonia fungi

67%
Zarnowski R., Kozubek A., Pietr S. J.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1999
|
tom 47
|
nr 2-4
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