Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: non-food protein

Sortuj według:

Ogranicz wyniki do:

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

The occurrence of sequences identical with epitopes from the allergen pen a 1.0102 among food and non-food proteins

100%

Minkiewicz P., Sokolowska J., Darewicz M.

Polish Journal of Food and Nutrition Sciences

2015

tom 65

nr 1

The presence of common epitopes among tropomyosins of invertebrates, including arthropods, e.g. edible ones, may help to explain the molecular basis of cross-reactivity between allergens. The work presented is the fi rst survey concerning global distribution of epitopes from Pen a 1.0102 in universal proteome. In the group of known tropomyosin epitopes, the fragment with the sequence ESKIVELEEEL was found in the sequence of channel catfish (Ictalurus punctatus) tropomyosin. To date, this is the fi rst result suggesting the presence of a complete sequential epitope interacting with IgE in vertebrate tropomyosin. Another fragment with the sequence VAALNRRIQL, a major part of the epitope, was found in 11 fi sh, 8 amphibians, 3 birds, 19 mammalians and 4 human tropomyosin sequences. Identical epitopes are common in sequences of invertebrate tropomyosins, including food and non-food allergens annotated in the Allergome database. The rare pentapeptide with the DEERM sequence occurs in proteins not sharing homology with tropomyosins. Pathogenic microorganisms are the most abundant category of organisms synthesizing such proteins.

Ograniczanie wyników

1 Polish Journal of Food and Nutrition Sciences

1 Darewicz M.

1 Minkiewicz P.

1 Sokolowska J.

1 2015

Wyniki wyszukiwania

The occurrence of sequences identical with epitopes from the allergen pen a 1.0102 among food and non-food proteins