Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: active stable maintenance function

Sortuj według:

Ogranicz wyniki do:

Active stable maintenance functions in low copy-number plasmids of Gram-positive bacteria. II. Post-segregational killing systems

100%

Dmowski M., Jagura-Burdzy G.

Polish Journal of Microbiology

2013

tom 62

nr 1

Active support is needed for low copy-number plasmids to be stably maintained in bacterial cells. The mechanisms that fulfill this role are (i) partition systems (PAR) acting to separate plasmid molecules to daughter cells and (ii) toxin-andidote (TA) (post-segregational killing-PSK) systems which arrest cell growth until the plasmid reaches the correct copy-number or kill the cells that have not inherited the plasmid. Our knowledge of toxin-antidote systems comes mainly from studies on Gram-negative bacteria. However, some addiction systems of Gram-positive bacteria have been characterized in detail or recently identified. Altogether, they bring new interesting data on toxin-antidote functioning in bacteria.

Active stable maintenance functions in low copy-number plasmids of Gram-positive bacteria. I. Partition systems

84%

Dmowski M., Jagura-Burdzy G.

Polish Journal of Microbiology

2013

tom 62

nr 1

Low copy number plasmids cannot rely on the random segregation during bacterial cell division. To be stably maintained in the population they evolved two types of mechanisms (i) partition systems (PAR) that actively separate replicated plasmid molecules to the daughter cells and (ii) toxin-andidote systems (TA) that act after cell division to kill plasmid-less cells. Our knowledge of partition systems has been based mainly on analysis of plasmids from Gram-negative bacteria. Now, numerous partition systems of plasmids from Gram-positive bacteria have also been characterized and make significant contribution to our understanding of these mechanisms.

Ograniczanie wyników

2 Polish Journal of Microbiology

2 Dmowski M.

2 Jagura-Burdzy G.

2 2013

Wyniki wyszukiwania

Active stable maintenance functions in low copy-number plasmids of Gram-positive bacteria. II. Post-segregational killing systems

Active stable maintenance functions in low copy-number plasmids of Gram-positive bacteria. I. Partition systems