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Histological and immunohistochemical characterisation of uterine adenocarcinoma in an Asian elephant (Elephas Maximus)

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Laricchiuta P., Russo V., Costagliola A., Piegari G., Capasso M., Silvestre P., Martano M., Paciello O.

Folia Morphologica

2018

tom 77

nr 4

A 56-year-old nulliparous female Asian elephant (Elephas maximus) living at the zoological garden of Naples (Italy), with a clinical history of recurrent colic, was found in agonal state and humane euthanasia was elected. At necropsy the uterine body was moderately increased in size and the lumen was reduced due to a poorly demarcated and infiltrative neoplasm. Furthermore, multiple, whitish, firm nodules were present in both lungs. Histological examination of the uterine mass revealed epithelial cells arranged in tubular or solid pattern infiltrating the endometrium and the muscular layer. Immunohistochemical examination showed immunoreactivity of neoplastic cells to oestrogen receptors antibody. Pulmonary lesions were histologically and immunohistochemically superimposable to the epithelial uterine neoplasm. A definitive diagnosis of uterine adenocarcinoma with pulmonary metastases was made. (Folia Morphol 2018; 77, 4: 771–774)

Ograniczanie wyników

1 Folia Morphologica

1 Capasso M.

1 Costagliola A.

1 Laricchiuta P.

1 Martano M.

1 Paciello O.

1 Piegari G.

1 Russo V.

1 Silvestre P.

1 2018

Wyniki wyszukiwania

Histological and immunohistochemical characterisation of uterine adenocarcinoma in an Asian elephant (Elephas Maximus)