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Torbiele watroby bablowcowe - problem diagnostyczny i leczniczy

100%

Snarska J., Puchalski Z., Hady H. R., Kokoszko M., Kondrusik M.

Wiadomości Parazytologiczne

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2000

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tom 46

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nr 1

117-122

In the Department of General Surgery of Medical University 11 patients with hydatid cysts of liver were operated. Ultrasonography and computer tomography allowed to define exact localization, size and contents of the cysts, what made possible planning of operating procedure. In 2 cases nonanatomic resection of liver parenchyma was performed, in 2 ones with coexisting stornach neoplasm just excision of the frontal wall of the cyst and emptying of the interior. In all the other cases the cysts were removed with surrounding liver tissue. Late results of surgical treatment with albendazol therapy are good. Diagnosis of echinococcic desease should be precised, considering with possibility of coexisting foci in other organs.

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Czas utrzymywania sie dodatnich wynikow badan serologicznych u osob operowanych z rozpoznaniem bablowicy watroby - obserwacje wlasne

100%

Kondrusik M., Pancewicz S. A., Zajkowska J. M., Hermanowska-Szpakowicz T., Snarska J.

Wiadomości Parazytologiczne

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1999

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tom 45

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nr 3

387-389

The purpose of this Work was to analyse results of serologie examinations and complaints reported by patients who were operated on echinococcal liver cysts. The analysis was conducted on patients who were qualified to surgical removal of echionococcal liver cysts. Persons who were analysed answered the questionaires and 11 of them send sera for serologie examination. The questionaires consisted of questions about time since operation, complaints before and after operation abdomen pains, distensions, vomits, exanthema, weakness, headaches). Results showed that patient were from 1 to 6 years after operation. Among 11 who send sera 18% results were negative (2 and 6 years after operation) and 82% was positive. Analysis of 15 questionnaires showed that majority of patients still had the complaints that were present before operation.

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The time of maintainance of positive serologic results among patients operated on echinococcal liver cysts

100%

Kondrusik M., Pancewicz S. A., Zajkowska J. M., Hermanowska-Szpakowicz T., Snarska J.

Wiadomości Parazytologiczne

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1998

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tom 44

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nr 3

4

Wystepowanie przeciwcial dla antygenow Francisella tularensis u pracownikow lesnych w wybranych regionach Polski

86%

Rastawicki W., Kurowska J., Hermanowska-Szpakowicz T., Pancewicz S. A., Kondrusik M., Jagielski M.

Medycyna Doświadczalna i Mikrobiologia

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2006

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tom 58

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nr 3

207-215

Oceniono częstość występowania przeciwciał dla F. tularensis u pracowników leśnych w wybranych regionach Polski. W żadnej z 480 badanych próbek surowicy uzyskanych od pracowników leśnych nic stwierdzono podwyższonego poziomu swoistych przeciwciał odczynem aglutynacji probówkowej. Odczynem ELISA obecność przeciwciał klasy IgA w mianie diagnostycznie znamiennym wykryto u 4,6%, przeciwciał klasy IgG u 3,8% i przeciwciał klasy IgM u 2,7% pracowników leśnych.

5

Detectibility of antibodies against Borrelia burgdorferi among forest workers in North-Eastern Poland

86%

Pancewicz S. A., Kondrusik M., Zajkowska J. M., Snarska-Furla I., Swierzbinska R., Hermanowska-Szpakowicz T.

Wiadomości Parazytologiczne

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1998

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tom 44

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nr 3

6

Vipera berus bites in Eastern Poland – a retrospective analysis of 15 case studies

72%

Garkowski A., Czupryna P., Zajkowska A., Pancewicz S., Moniuszko A., Kondrusik M., Grygorczuk S., Golebicki P., Letmanowski M., Zajkowska J.

Annals of Agricultural and Environmental Medicine

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2012

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tom 19

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nr 4

7

Assessment of the frequency of different Borrelia burgdorferi sensu lato species in patients with Lyme borreliosis from north-east Poland by studying preferential serologic response and DNA isolates

72%

Grygorczuk S., Peter O., Kondrusik M., Moniuszko A., Zajkowska J., Dunaj J., Zukiewicz-Sobczak W., Pancewicz S.

Annals of Agricultural and Environmental Medicine

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2013

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tom 20

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nr 1

Introduction and objective. Several Borrelia burgdorferi sensu lato species cause Lyme borreliosis throughout Europe and their geographic distribution may influence clinical manifestations of the disease. In Poland, Lyme borreliosis presents mainly with neurologic and cutaneous symptoms, while clinically overt arthritis is rare. The presented study investigates the prevalence of B. burgdorferi s.l. genospecies in a group of patients with different clinical forms and stages of Lyme borreliosis in north-east of Poland. This has not previously been studied. Material and methods. Preferential reactivity towards different B.burgdorferi s.l. species was investigated with a previously validated immunoblot assay in sera of 33 patients with disseminated Lyme borreliosis: 10 with neuroborreliosis, 6 with acrodermatitis chronica atrophicans and 17 with osteoarticular symptoms. Also typed were B.burgdorferi s.l. DNA isolated from the skin and synovial fluid of 7 patients with erythema migrans, acrodermatitis chronic atrophicans and arthritis. Results. Preferential reactivity was detected in 30 out of 33 serum samples. Of these, 25 reacted preferentially with B.afzelii, 3 with B. garinii and 2 with B. burgdorferi ss. B.burgdorferi DNA was isolated from all studied samples and typed as B.afzelii in 5. In a patient with acrodermatitis chronica atrophicans studied with both methods simultaneously, B.afzelii was identified by both genotyping and serotyping. Conclusions. Both methods gave consistent results, indicating B.afzelii as the main agent of all the clinical forms of the Lyme borreliosis in the study area.

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Synthesis of Th17 cytokines in the culture of peripheral blood mononuclear cells stimulated with Borrelia burgdorferi sensu lato

72%

Grygorczuk S., Swierzbinska R., Moniuszko A., Kondrusik M., Zajkowska J., Czupryna P., Dunaj J., Pancewicz S.

Annals of Agricultural and Environmental Medicine

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2016

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tom 23

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nr 2

9

Borrelia burgdorferi genospecies detection by RLB hybridization in Ixodes ricinus ticks from different sites of North-Eastern Poland

72%

Dunaj J., Zakowska J., Kondrusik M., Gern L., Rais O., Moniuszko A., Pancewicz S., Swierzbinska R.

Annals of Agricultural and Environmental Medicine

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2014

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tom 21

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nr 2

10

Molecular and serological diagnosis of Borrellia burgdorferi infection among patients with diagnosed erythema migrans

72%

Kondrusik M., Grygorczuk S., Skotarczak B., Wodecka B., Rymaszewska A., Pancewicz S., Zajkowska J., Swierzbinska R., Hermanowska-Szpakowicz T.

Annals of Agricultural and Environmental Medicine

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2007

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tom 14

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nr 2

The aim of the study was to assess the frequency of Borrelia burgdorferi DNA detection in the blood and urine of patients diagnosed with erythema migrans, and compare the results of PCR-based methods with ELISA methodology. The latter was used to detect serum antibodies against Borrelia burgdorferi of the IgM and IgG classes, before and after antibiotic therapy. The study included 86 patients hospitalized in the Department of Infectious Diseases and Neuroinfections in the Medical Academy in Białystok, diagnosed with the erythema migrans phase of Lyme borreliosis. Examinations were carried out twice: the fi rst at the moment of diagnosis (Trial 1), the second after 4 weeks of antibiotic therapy. The study showed that antibiotic therapy in the early phase of borreliosis does not decrease the sensitivity of PCR and that after 4 weeks of therapy (Trial 2), spirochete DNA is still detectable in most patients (45/86). There was no correlation between detectability of spirochete DNA and the presence of antibodies against B. burgdorferi s.l. (assessed by ELISA) during the course of erythema migrans. The largest percentage of positive results in the detection of B. burgdorferi s.l. DNA was observed in patients who simultaneously possessed IgM and IgG antibodies against B. burgdorferi, while the lowest percentage of PCR positive results was among patients with only IgM antibodies.

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Detecting DNAs of Anaplasma phagocytophilum and Babesia in the blood of patients suspected of Lyme disease

72%

Hermanowska-Szpakowicz T., Skotarczak B., Kondrusik M., Rymaszewska A., Sawczuk M., Maciejewska A., Adamska M., Pancewicz S., Zajkowska J.

Annals of Agricultural and Environmental Medicine

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2004

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tom 11

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nr 2

Co-occurrence of granulocytic anaplasmosis, borreliosis and babesiosis in humans is a result of common vectors for the respective pathogens of these diseases, most commonly ticks from the genus Ixodes. Studies on ticks in Europe and also in Poland have shown that several pathogens may co-occur in individuals of I. ricnus. A total of 96 hospitalised patients infected or suspected of being infected with borreliosis were screened for A. phagocytophilum and Babesia sp. DNA. Positive results of PCRs for A. phagocytophilum DNA were obtained for 10 patients, 8 of whom were diagnosed with borreliosis earlier, and 4 of whom were diagnosed with tick-borne encephalitis (on the basis of serological studies of serum and cerebrospinal fluid). None of the 10 patients had clinical or biochemical markers of anaplasmosis, corroborating the existence of asymptomatic anaplasmosis or self-limiting course. in Europe. Similarly, Babesia DNA was not found in the blood of any of the patients. The results of the studies show that in diagnosing tick-borne diseases, clinical examinations should consider infection by two or even three tick-borne pathogens.

Ograniczanie wyników

Torbiele watroby bablowcowe - problem diagnostyczny i leczniczy

Czas utrzymywania sie dodatnich wynikow badan serologicznych u osob operowanych z rozpoznaniem bablowicy watroby - obserwacje wlasne

The time of maintainance of positive serologic results among patients operated on echinococcal liver cysts

Wystepowanie przeciwcial dla antygenow Francisella tularensis u pracownikow lesnych w wybranych regionach Polski

Detectibility of antibodies against Borrelia burgdorferi among forest workers in North-Eastern Poland

Vipera berus bites in Eastern Poland – a retrospective analysis of 15 case studies

Assessment of the frequency of different Borrelia burgdorferi sensu lato species in patients with Lyme borreliosis from north-east Poland by studying preferential serologic response and DNA isolates

Synthesis of Th17 cytokines in the culture of peripheral blood mononuclear cells stimulated with Borrelia burgdorferi sensu lato

Borrelia burgdorferi genospecies detection by RLB hybridization in Ixodes ricinus ticks from different sites of North-Eastern Poland

Molecular and serological diagnosis of Borrellia burgdorferi infection among patients with diagnosed erythema migrans

Detecting DNAs of Anaplasma phagocytophilum and Babesia in the blood of patients suspected of Lyme disease