Wyniki wyszukiwania

1

Heptaminol - nowy lek weterynaryjny o efektach sercowo-naczyniowych

100%

Rolinski Z., Skrobisz J.

Medycyna Weterynaryjna

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1997

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tom 53

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nr 08

427-429

2

Komputerowa analiza antybiogramow drobnoustrojow izolowanych od bydla i owiec

81%

Rolinski Z., Sobol M., Skrobisz J.

Medycyna Weterynaryjna

|

1999

|

tom 55

|

nr 01

30-33

3

Komputerowa analiza antybiogramow drobnoustrojow izolowanych od trzody chlewnej

81%

Rolinski Z., Skrobisz J., Kowalski C., Sobol M.

Medycyna Weterynaryjna

|

1998

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tom 54

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nr 04

247-252

The article presents data of a computer analysis of the antibiotic resistance patterns and results of evaluations of the level of antibiotic resistance of Gram positive and Gram negative bacteria isolated from pigs in 1985-1990, performed in diagnostic laboratories of the Centers of Veterinary Hygiene in Białystok, Katowice, Olsztyn, Poznań, Warszawa and Wrocław. The resistance of Escherichia coli (non-haemolytic, haemolytic and β-haemolytic), Pasteurella multocida, Salmonella typhimurium, S. choleraesuis, S. enteritidis, Salmonella of the В group, Streptococcus β-haemolyticus against ampicillin, chloramphenicol, erythromycin, neomycin, nitrofurantoin, oxytetracycline, penicillin, streptomycin, sulphonamides, sulphonamides + TMP and TMP was analyzed. A high level of resistance of E. coli isolates (54-97%) to ampicillin, oxytetracycline, sulphonamides and sulphonamides potentiated with TMP and a low level of resistance (26-42%) to nitrofurantoin, neomycin, streptomycin and chloramphenicol were determined. P. multocida isolated were characterized by a high level of resistance to sulphonamides and sulphonamides potentiated with TMP (61-85%) and a low resistance to oxytetracycline (32%). Salmonella sp. was characterized by a very low resistance (51-74%). S. β-haemolyticus had (62%) and a lower resistance to streptomycin (46%), penicillin (24%) and nitrofurantion (23%).

4

Alternative 3’ acceptor site in the exon 2 of human PAX8 gene resulting in the expression of unknown mRNA variant found in thyroid hemiagenesis and some types of cancers

51%

Szczepanek-Parulska E., Szaflarski W., Piatek K., Budny B., Jaszczynska-Nowinka K., Biczysko M., Wierzbicki T., Skrobisz J., Zabel M., Ruchala M.

Acta Biochimica Polonica

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2013

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tom 60

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nr 4

PAX8 gene encodes one of the transcription factors engaged in the regulation of proper development of thyroid gland as well as Müllerian and renal/upper urinary tracts. So far, six alternatively spliced transcripts were reported, however, sequences of only four were deposited in the NCBI database. Here, we evaluate a fragment of a novel variant of PAX8 mRNA formed by an alternative 3' acceptor site located in the second exon. The molecular outcome encompasses extension of the 5' untranslated region of exon two by 97 nucleotides as is evident from mRNA. This new insert may impair binding of mRNA to the ribosome and in consequence significantly decrease expression of the PAX8 protein. Here, we show for the first time that the novel insert in exon two might be associated with congenital thyroid hemiagenesis and influence development of different types of cancer.

Ograniczanie wyników

3 Medycyna Weterynaryjna

1 Acta Biochimica Polonica

4 Skrobisz J.

3 Rolinski Z.

2 Sobol M.

1 Biczysko M.

1 Budny B.

1 Jaszczynska-Nowinka K.

1 Kowalski C.

1 Piatek K.

1 Ruchala M.

1 Szaflarski W.

1 Szczepanek-Parulska E.

1 Wierzbicki T.

1 Zabel M.

1 2013

1 1999

1 1998

1 1997

Heptaminol - nowy lek weterynaryjny o efektach sercowo-naczyniowych

Komputerowa analiza antybiogramow drobnoustrojow izolowanych od bydla i owiec

Komputerowa analiza antybiogramow drobnoustrojow izolowanych od trzody chlewnej

Alternative 3’ acceptor site in the exon 2 of human PAX8 gene resulting in the expression of unknown mRNA variant found in thyroid hemiagenesis and some types of cancers