Wyniki wyszukiwania

1

Bocian bialy - najbardziej oczekiwany poslaniec wiosny

100%

Pawlak D.

Ptaki. Biuletyn Ogólnopolskiego Towarzystwa Ochrony Ptaków

|

2007

|

nr 1

17-18

2

Dokarmianie ptakow zima - przyjemnosc i odpowiedzialnosc

100%

Pawlak D.

Ptaki. Biuletyn Ogólnopolskiego Towarzystwa Ochrony Ptaków

|

2006

|

nr 3-4

43-44

3

Birdfair - to trzeba przezyc

100%

Pawlak D.

Ptaki. Biuletyn Ogólnopolskiego Towarzystwa Ochrony Ptaków

|

2006

|

nr 3-4

24-26

4

Digital printing in wood industry

63%

Pawlak D., Boruszewski P.

Annals of Warsaw University of Life Sciences - SGGW. Forestry and Wood Technology

|

2020

|

tom 109

9

Dla ptakow i dla ludzi - oczko wodne

63%

Pawlak D., Zaniewicz B.

Ptaki. Biuletyn Ogólnopolskiego Towarzystwa Ochrony Ptaków

|

2007

|

nr 2

12-13

10

Szlak kinureninowy w zdrowiu i w chorobie

63%

Mysliwiec P., Pawlak D.

Postępy Higieny i Medycyny Doświadczalnej

|

2000

|

tom 54

|

nr 2

239-252

11

Modyfikowane kompozyty warstwowe

51%

Radziejewicz D., Pawlak D., Bereska B., Boruszewski P.

Biuletyn Informacyjny Ośrodka Badawczo-Rozwojowego Przemysłu Płyt Drewnopochodnych w Czarnej Wodzie

|

2018

|

tom 59

|

nr 3-4

13

Intracellular mechanisms of tumor cells’ immunoresistance

51%

Hermanowicz J. M., Sieklucka B., Nosek K., Pawlak D.

Acta Biochimica Polonica

|

2020

|

tom 67

|

nr 2

14

Analiza wpływu okresu sezonowania płyt wiórowych na ich właściwości mechaniczne

51%

Lieber E., Pawlak D., Boruszewski P.

Biuletyn Informacyjny Ośrodka Badawczo-Rozwojowego Przemysłu Płyt Drewnopochodnych w Czarnej Wodzie

|

2018

|

tom 59

|

nr 1-2

15

Enzymy szlaku kinureninowego

51%

Tankiewicz A., Pawlak D., Buczko W.

Postępy Higieny i Medycyny Doświadczalnej

|

2001

|

tom 55

|

nr 5

715-731

16

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

New insight into organic anion transporters from the perspective of potentially important interactions and drugs toxicity

51%

Mor A. L., Kaminski T. W., Karbowska M., Pawlak D.

Journal of Physiology and Pharmacology

|

2018

|

tom 69

|

nr 3

17

Peripheral distribution of kynurenine metabolites and activity of kynurenine pathway enzymes in renal failure

51%

Pawlak D., Tankiewicz A., Matys T., Buczko W.

Journal of Physiology and Pharmacology

|

2003

|

tom 54

|

nr 2

We investigated L-kynurenine distribution and metabolism in rats with experimental chronic renal failure of various severity, induced by unilateral nephrectomy and partial removal of contralateral kidney cortex. In animals with renal insufficiency the plasma concentration and the content of L-tryptophan in homogenates of kidney, liver, lung, intestine and spleen were significantly decreased. These changes were accompanied by increase activity of liver tryptophan 2,3-dioxygenase, the rate-limiting enzyme of kynurenine pathway in rats, while indoleamine 2,3-dioxygenase activity was unchanged. Conversely, the plasma concentration and tissue content of L-kynurenine, 3-hydroxykynurenine, and anthranilic, kynurenic, xanthurenic and quinolinic acids in the kidney, liver, lung, intestine, spleen and muscles were increased. The accumulation of L-kynurenine and the products of its degradation was proportional to the severity of renal failure and correlated with the concentration of renal insufficiency marker, creatinine. Kynurenine aminotransferase, kynureninase and 3-hydroxyanthranilate-3,4-dioxygenase activity was diminished or unchanged, while the activity of kynurenine 3-hydroxylase was significantly increased. We conclude that chronic renal failure is associated with the accumulation of L-kynurenine metabolites, which may be involved in the pathogenesis of certain uremic syndromes.

18

Conformational analysis of a novel cyclic enkephalin analogue using NMR and EDMC calculations

51%

Sidor M., Wojcik J., Pawlak D., Izdebski J.

Acta Biochimica Polonica

|

1999

|

tom 46

|

nr 3

Conformational space of a novel cyclic enkephalin analogue, cyclo(Nε, Nε'-carbonyl-D-Lys2,Lys5) enkephalinamide, was exhaustively examined. A large number of conformations was selected and clustered into families on the basis of their structure and energy. For representative conformations ROESY spectra were generated and their linear combination was fitted to the spectra measured in water and Me2-SO-d6. This procedure yielded an ensemble of most populated conformations of the peptide in the two solvents.

19

Kynurenine and its metabolites in the rat with experimental renal insufficiency

51%

Pawlak D., Tankiewicz A., Buczko W.

Journal of Physiology and Pharmacology

|

2001

|

tom 52

|

nr 4,2

In uremia a great number of the endogenous metabolites that are ordinarily excreted in urine accumulate in the blood. Among these are the products of KYN degradation. In the present study we evaluated the peripheral KYN metabolism in the various stages of the rat experimental chronic renal insufficiency. Our results showed significant disturbances in peripheral kynurenic pathway, which resulted in the significant decrease of TRP plasma level and augmentation of concentration of its metabolites. The high concentrations of 3-hydroxykynurenine, xanthurenic acid, kynurenic acid, anthranilic acid and quinolinic acid positively correlated with degree of the renal insufficiency. Talking into account the biological properties of KYN metabolites, their accumulation in the blood, may be at least partially, responsible for severity of uremia as well as for uremic symptoms such as neuropathy, increased susceptibility to infections, hypertension, lipid disturbances and anemia.

20

Subjective vs objective evaluation of knee stability in patients before and after anterior cruciate ligament reconstruction

45%

Wysota A., Pawlak D., Ficek K., Ficek J., Juras G.

Central European Journal of Sport Sciences and Medicine

|

2014

|

tom 06

|

nr 2

Every year, the number of anterior cruciate ligament ruptures increases considerably. The present analysis compares patients’ subjective sensations after the ACL injury to an objective arthrometric examination. The subjective evaluation of the knee-joint condition was performed using the Lysholm score scale and IKDC 2000 scale, whereas the objective evaluation was performed using a GNRB device to obtain an arthrometric measurement. Both measurement methods were performed before ACL reconstruction and after the rehabilitation process of ±11.5 months. The following research was conducted on a group of 8 patients who underwent anterior cruciate ligament reconstruction. Statistical analysis did not reveal any significant differences between the arthrometric examination and the subjective score scales. The test indicated the significant differences between the score scales questionnaires completed before and after the surgery. The conclusions that can be drawn from the present analysis show us the importance of using subjective evaluation devices. Despite the lack of significance in the examination performed with the objective device, the self-evaluation of kneejoint efficiency made by the patient indicated a significant improvement.

Ograniczanie wyników

Bocian bialy - najbardziej oczekiwany poslaniec wiosny

Dokarmianie ptakow zima - przyjemnosc i odpowiedzialnosc

Birdfair - to trzeba przezyc

Pochwal się dobrą praktyką

Pochwal się dobrą praktyką

Pochwal się dobrym projektem

Na pomoc zającom

Digital printing in wood industry

Dla ptakow i dla ludzi - oczko wodne

Szlak kinureninowy w zdrowiu i w chorobie

Od ankiety do finansowania

Modyfikowane kompozyty warstwowe

Intracellular mechanisms of tumor cells’ immunoresistance

Analiza wpływu okresu sezonowania płyt wiórowych na ich właściwości mechaniczne

Enzymy szlaku kinureninowego

New insight into organic anion transporters from the perspective of potentially important interactions and drugs toxicity

Peripheral distribution of kynurenine metabolites and activity of kynurenine pathway enzymes in renal failure

Conformational analysis of a novel cyclic enkephalin analogue using NMR and EDMC calculations

Kynurenine and its metabolites in the rat with experimental renal insufficiency

Subjective vs objective evaluation of knee stability in patients before and after anterior cruciate ligament reconstruction