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Przeciwpradowe przenikanie i zwrotny transport progesteronu, oksytocyny i prostaglandyny F2 alfa w obszarze wiezadla szerokiego macicy krow w czasie trwania fazy lutealnej

100%

Koziorowski M.

Acta Academiae Agriculturae ac Technicae Olstenensis. Veterinaria

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1996

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tom 22,Suppl.G

1-43

W pracy przedstawiono wyniki badań własnych dotyczących przeciwprądowego przenikania z krwi żylnej i limfy do krwi tętniczej progesteronu, oksytocyny i prostaglandyny F2α w obszarze więzadła szerokiego macicy u krów będących w fazie lutealnej cyklu estralnego i na tym tle rozpatrzono znaczenie tego procesu w regulacji rozrodu u krowy. Progesteron wytwarzany przez ciałko żółte w czasie fazy lutealnej opuszcza jajnik z krwią żyły jajnikowej i limfą. W obszarze naczyń krezki jajnika (mesovarium) ulega przeciwprądowemu przenikaniu do krwi tętnicy jajnikowej. Powstaje zwiększona lokalna koncentracja progesteronu w tym obszarze, a przez gałąź maciczną tętnicy jajnikowej również w obszarze macicy i jajowodu. Sugeruje się, że tą drogą zwiększona lokalnie koncentracja progesteronu bierze udział w przygotowaniu macicy do spełnienia funkcji wydzielniczej, a szczególnie ma to znaczenie w sekrecji PGF2α. Wykazano również przeciwprądowe przenikanie i transport jajnikowej oksytocyny z krwi żylnej odpływającej z jajnika do krwi tętniczej zaopatrującej zarówno jajnik, jak i przez odgałęzienie tętnicy jajnikowej - macicę i jajowód. Sugeruje się, że lokalna koncentracja oksytocyny w obszarze macicy i jajowodu ma na celu zapoczątkowanie zmian, zarówno naczyniowych, jak i wydzielniczych, związanych ze zbliżającą się luteolizą. Wykazano przeciwprądowe, zwrotne przenikanie PGF2α z krwi żylnej do krwi tętniczej w obszarze krezki macicy (mesometrium), przy czym proces ten z większą intensywnością przebiegał po stronie ciałka żółtego. Proces ten ma za zadanie ochronę aktywnego ciałka żółtego przed luteolizą.

2

Przeciwpradowe przenikanie i zwrotny transfer hormonow w obszarze naczyniowym meskiego ukladu rozrodczego

100%

Koziorowski M.

Życie Weterynaryjne

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2006

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tom 81

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nr 02

128-130

3

Pakowanie w foliach barierowych - zlo konieczne, czy szansa rozwoju

100%

Koziorowski M.

Dostawcy dla Przemysłu Mięsnego

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2003

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nr 6

38-40

4

Pakowanie w foliach barierowych - nowe szanse dla zakladow mleczarskich

100%

Koziorowski M.

Dostawcy dla Przemysłu Mleczarskiego

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2004

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nr 1

27-30

5

Local hormonal regulations in female reproductive organs of domestic animals

63%

Koziorowski M., Stefanczyk-Krzymowska S.

Polish Journal of Natural Sciences

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2007

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tom 22

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nr 4

742-752

The discovery of local transfer of ovarian hormones (steroids, oxytocin) and uterine prostaglandins (PGF2α and PGE2) in cow, ewe and sow created a new point of view on hormonal regulation of the reproduction and thereby on the regulation of the estrous cycle of the female. It was demonstrated that retrograde transfer of hormones to the place of its secretion and destination transfer of ovarian hormones to the oviduct and uterus, and uterine prostaglandins to the ovary and oviduct is realized on the base of morphological and physiological adaptations of blood and lymphatic vessels of the mesovarium and mesometrium. These processes result in continuous local elevation of the concentration of sex hormones in blood supplying female reproductive organs by 30-70% in comparison with systemic arterial blood. Local destination and retrograde transfer of ovarian hormones and uterine prostaglandins is a way by which reproductive organs are selectively supplied with increased amount of these hormones, adequate to their needs.

6

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Morphological defects of epididymal spermatozoa in male roe deer (Capreolus capreolus) during the reproductive season

63%

Koziol K., Koziorowski M.

Polish Journal of Veterinary Sciences

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2015

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tom 18

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nr 3

The aim of this study was to analyse the morphology of the epididymal spermatozoa of male roe deer obtained postmortem at the beginning (May), peak (July/August) and the end (September) of the reproductive season. Spermatozoal abnormalities were divided into major (associated with impaired fertility) and minor (not associated with impaired fertility) defects. The highest percentage of abnormal spermatozoa was observed in May (17.78 ± 1.88%), with a much higher proportion of major (12.35 ± 1.11%) than minor defects (5.43 ± 1.59%) being observed. The percentage of abnormal spermatozoa was lowest during the peak of the reproductive season (4.97 ± 1.13%), with the proportion of major (2.68 ± 0.78%) and minor defects (2.28 ± 0.45%) being comparable during this period. The percentage of abnormal spermatozoa increased again in September (11.05 ± 1.60%), with the major defects (6.15 ± 1.04%) slightly surpassing the minor defects (4.90 ± 0.77%); however, total abnormalities still remained lower than those found in May. These differences were statistically significant, with the exception of the difference in minor defects between the pre-rut and post-rut periods. These results indicate that the best period to collect epididymal spermatozoa from roe deer postmortem is the peak of the reproductive season (July/August); however, they can also be recovered at the end of the reproductive season (September), as the percentage of major defects is relatively low at this time. This study provides the basis for further research to determine optimal methods for the storage and cryopreservation of epididymal spermatozoa in this species.

7

The gonadotropins subunits, GNRH and GnRH receptor gene expression and role of carbon monoxide in seasonal breeding animals

63%

Romerowicz-Misielak M., Koziorowski M.

Annals of Animal Science

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2012

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tom 12

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nr 1

8

Swiniodziki - szansa czy iluzja

63%

Koziorowski M.

Hodowca Trzody Chlewnej

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2004

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nr 1

30-31

9

Rozród zwierząt nieudomowionych – osiągnięcia nauki krajowej i jej perspektywy na tle badań światowych

51%

Koziorowski M., Gizejewski Z., Gilun P.

Postępy Nauk Rolniczych

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2007

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tom 59

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nr 3

10

Local transfer of testosterone and aromatase activity in the spermatic cord in wild boar/pig hybrids in short-daylight and long-daylight periods

51%

Tabecka-Lonczynska A., Gilun P., Stefanczyk-Krzymowska S., Koziorowski M.

Reproductive Biology

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2014

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tom 14

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nr 4

11

The expression of genes encoding opioid precursors and the influence of opioid receptor agonists on steroidogenesis in porcine adrenocortical cells in vitro

51%

Krazinski B. E., Koziorowski M., Brzuzan P., Okrasa S.

Journal of Physiology and Pharmacology

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2011

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tom 62

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nr 4

12

Presence of erythropoiesis inhibitor in the urine of normal sheep and those with transfused polycythemia

51%

Kotwica G., Koziorowski M., Krzymowska H.

Acta Physiologica Polonica

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1978

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tom 29

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nr 1

13

Counter current transfer of PGF2alfa in the mesometrial vessels as a mechanism for prevention of luteal regression in early pregnancy

51%

Krzymowski T., Stefanczyk-Krzymowska S., Koziorowski M.

Acta Physiologica Polonica

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1989

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tom 40

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nr 1

Krzymowski, T., Stefańczyk-Krzymowska, S. and Koziorowski, M.: Counter current transfer of PGF₂ α in the mesometrial vessels as a mechanism for tprevention of luteal regression in early pregnancy. Acta physiol, pol., 1989, 40 (1): 23-34. A new concept has been presented on the mechanism protecting the corpus luteum during oestrouis cycle, early pregnancy and pseudopregnancy induced by oestrogens. The concept is based on the recently discovered mechanism of (back transfer of prostaglandin F₂ α from the broad ligament vasculature into the uterus and on the participation of oestrogen in this process. The morphological facilitates for counter-current transfer of PGF₂α in the area of mesometrial vasculature and ability the uterus to bind PGF₂α were presented. It has been concluded that the process of PGF₂α back-transfer from mesometrial vasculature into the uterus may reduce in uterine venous blood the amplitude of PGF₂α pulses and by his way may reduce the penetration of prostaglandin into subovarian area and from there to the corpus luteum.

14

Expression of hypoxia-inducible factor-1alfa and association with Cu/Zn superoxide dismutase in the reproductive tract tissues of adult male roe deer (Capreolus capreolus) during the reproduction season

51%

Koziorowska-Gilun M., Gilun P., Koziorowski M., Kordan W.

Annals of Animal Science

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2017

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tom 17

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nr 4

15

Antioxidant status of spermatoza of cauda epididymis and fluids of accessory sex glads of boar

51%

Koziorowska-Gilun M., Kowalowka M., Koziorowski M., Strzezek J.

Acta Biochimica Polonica

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2006

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tom 53

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nr Supplement 1

16

Counter current transfer and back transport of 3H-PGF2alfa in the cow's broad ligament vasculature ipsilateral and contralateral to the corpus luteum

51%

Koziorowski M., Stefanczyk-Krzymowska S., Czarnocki J., Krzymowski T.

Acta Physiologica Polonica

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1989

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tom 40

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nr 1

Koziorowski, M., Stefańczyk-Krzymowska, S., Czarnocki, J. and Krzymowski, T.: Counter.,current transfer and badk transport of 3H-PGF₂ α in the cow's broad ligament vasculature ipsilateral and contralateral to the corpus luteum. Acta, physiol, poll., 1989, 40 (1): 96-103. Eight cowis of similar age (5-7 yeras) were chosen for the experiment. Isolated reproductive tract was supplied with autologous oxygenated and heated (40 ⁰C) blood through the uterine artery and ovaitian artery. 3H-PGF₂α in totial dose of 2 MBq (10⁷ cpm) was injected into each of the uterine lumen of isollaited organ. Blood samples were collected at 5 min intervals during .120 min of experiment using cannulae inserted into the branches of uterine arteries about 1 cm below the horns and from ovarian arteries inserted 0.5 cm below the ovaries. The concentration of 3H-PGF₂α found in blood plasma taken from uterine artery or from ovarian artery on the side wiith active corpus luteum (CL) was significantly lower (p < 0.001) compare with contralateral side to active CL. Radioactive PGF₂α found in.branches of uterine arteries on both lipsiilateral and contralateral side to CL was significantly higher i(p < 0.001) compare to ovarian artery Of the. same side.It is concluded that absorption of 3H-PGF₂α from uterine lumen into venous blood as well as its counter current transfer in area of broad ligament vasculature were reduced on the side of uterine horn with active CL probably as an effect of estrogen : progesteron ratio on vascular constriction in area of Uterine vasculature.

17

Counter current transfer of oxytocin in vasculature of cows broad ligament

51%

Koziorowski M., Stefanczyk-Krzymowska S., Czarnocki J., Krzymowski T.

Bulletin of the Polish Academy of Sciences. Biological Sciences

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1989

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tom 37

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nr 4-6

18

Seasonal changes in antioxidant defence systems in seminal plasma and fluids of the boar reproductive tract

51%

Koziorowska-Gilun M., Koziorowski M., Strzezek J., Fraser L.

Reproductive Biology

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2011

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tom 11

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nr 1

19

A local pathway for increased testosterone supply from the testis to the epididymis, vas deferens and accessory genital glands of the rat

45%

Krzymowski T., Stefanczyk-Krzymowska S., Gilun P., Radomski M., Koziorowski M.

Polish Journal of Veterinary Sciences

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2005

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tom 08

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nr 3

20

Cavernous sinus and its mysterious physiological functions: facts and hypotheses

45%

Krzymowski T., Stefanczyk-Krzymowska S., Muszak J., Gilun P., Koziorowski M.

Acta Biologica Cracoviensia. Series Zoologia

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2013-2014

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tom 55-56

Ograniczanie wyników

Przeciwpradowe przenikanie i zwrotny transport progesteronu, oksytocyny i prostaglandyny F2 alfa w obszarze wiezadla szerokiego macicy krow w czasie trwania fazy lutealnej

Przeciwpradowe przenikanie i zwrotny transfer hormonow w obszarze naczyniowym meskiego ukladu rozrodczego

Pakowanie w foliach barierowych - zlo konieczne, czy szansa rozwoju

Pakowanie w foliach barierowych - nowe szanse dla zakladow mleczarskich

Local hormonal regulations in female reproductive organs of domestic animals

Morphological defects of epididymal spermatozoa in male roe deer (Capreolus capreolus) during the reproductive season

The gonadotropins subunits, GNRH and GnRH receptor gene expression and role of carbon monoxide in seasonal breeding animals

Swiniodziki - szansa czy iluzja

Rozród zwierząt nieudomowionych – osiągnięcia nauki krajowej i jej perspektywy na tle badań światowych

Local transfer of testosterone and aromatase activity in the spermatic cord in wild boar/pig hybrids in short-daylight and long-daylight periods

The expression of genes encoding opioid precursors and the influence of opioid receptor agonists on steroidogenesis in porcine adrenocortical cells in vitro

Presence of erythropoiesis inhibitor in the urine of normal sheep and those with transfused polycythemia

Counter current transfer of PGF2alfa in the mesometrial vessels as a mechanism for prevention of luteal regression in early pregnancy

Expression of hypoxia-inducible factor-1alfa and association with Cu/Zn superoxide dismutase in the reproductive tract tissues of adult male roe deer (Capreolus capreolus) during the reproduction season

Antioxidant status of spermatoza of cauda epididymis and fluids of accessory sex glads of boar

Counter current transfer and back transport of 3H-PGF2alfa in the cow's broad ligament vasculature ipsilateral and contralateral to the corpus luteum