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1

The effect of oxytocin and VIP on the LH secretion by porcine pituitary cells after treatment with exogenous estrogen

100%
Bogacka I.
Acta Neurobiologiae Experimentalis
|
1996
|
tom 56
|
nr 3
2
Content available remote

The quantitative expression of peroxisome proliferator activated receptor (PPAR) genes in porcine endometrium through the estrous cycle and early pregnancy

63%
Bogacka I., Bogacki M.
Journal of Physiology and Pharmacology
|
2011
|
tom 62
|
nr 5
3

Rola receptorow aktywowanych przez proliferatory peroksysomow gamma [PPARgamma] w procesie adipogenezy oraz rozwoju otylosci i cukrzycy typu 2

63%
Bogacka I., Ligocka A.
Postępy Biologii Komórki
|
2008
|
tom 35
|
nr 1
15-30
4

Regulacja pobierania pokarmu na poziomie osrodkowego ukladu nerwowego u otylych szczurow Zucker [fa-fa] - rola leptyny

63%
Bogacka I., Malesa J.
Postępy Biologii Komórki
|
2007
|
tom 34
|
nr 1
173-188
5

The effect of oxytocin [OT] and VIP on the PRL and LH secretion by porcine pituitary cells after treatment with exogenous progesterone

63%
Bogacka I., Przala J.
Folia Histochemica et Cytobiologica. Supplement
|
1997
|
tom 35
|
nr 2
6

Receptory aktywowane przez proliferatory peroksysomow i ich rola w rozrodzie

51%
Kaminska K., Bogacka I., Wasielak M., Bogacki M.
Medycyna Weterynaryjna
|
2008
|
tom 64
|
nr 04B
533-536
Peroxisome proliferator activated receptors (PPARs) are transcriptional factors belonging to the nuclear receptor superfamily. Three members of the PPAR family have been characterized as PPARα, PPARβ and PPARγ, encoded by separate genes. These isoforms exhibit diverse expression patterns and are activated by different ligands that cause various biological effects. The PPARs are mainly responsible for homeostasis and lipid metabolism. Recently it has been discovered that PPARs play a crucial role in the female reproductive system. PPARγ is expressed in the ovary, endometrium, placenta and fetal membranes. The lack of functional receptors PPARγ or PPARβ results in aberrant placentation and leads to lethality in rodents. PPARβ is abundantly expressed at implantation sites in mice uteri which suggests its role in implantation. Summarizing, in the recent decade studies have revealed new functions of PPARs as the family of receptors that regulate reproductive processes.
7

Peroxisome proliferator-activated receptors in the regulation of female reproductive functions

51%
Bogacka I., Kurzynska A., Bogacki M., Chojnowska K.
Folia Histochemica et Cytobiologica
|
2015
|
tom 53
|
nr 3
8
Content available remote

Peroxisome proliferator activated receptor ligands affect progesterone and 17beta-estradiol secretion by porcine corpus luteum during early pregnancy

51%
Kurzynska A., Bogacki M., Chojnowska K., Bogacka I.
Journal of Physiology and Pharmacology
|
2014
|
tom 65
|
nr 5
9

The involvement of peroxisome proliferator activated receptors (PPARs) in prostaglandin F2α production by porcine endometrium

51%
Bogacka I., Bogacki M., Kurzynska A., Chojnowska K.
Reproductive Biology
|
2013
|
tom 13
|
nr 4
10

Expression of peroxisome proliferator activated receptor (PPAR) genes in porcine endometrium exposed in vitro to IL-6 and INFγ

51%
Bogacka I., Bogacki M., Boruszewska D., Wasielak M.
Reproductive Biology
|
2012
|
tom 12
|
nr 2
11

The role of opioids in porcine corpus luteum function

51%
Przala J., Kaminski T., Bogacka I., Siawrys G.
Journal of Physiology and Pharmacology. Supplement
|
1996
|
tom 47
|
nr 1
12

Cyclic AMP and cGMP production by isolated small and large porcine luteal cells - effect of hCG and TNFalpha

51%
Przala J., Bogacka I., Siawrys G.
Folia Histochemica et Cytobiologica. Supplement
|
1997
|
tom 35
|
nr 2
13

Udzial opioidow w lokalnej regulacji funkcji jajnika

45%
Przala J., Kaminski T., Okrasa S., Siawrys G., Bogacka I.
Postępy Biologii Komórki. Suplement
|
1999
|
tom 12
113-116
14
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Content available

The effect of progesterone on oxytocin-stimulated intracellular Ca2plus mobilisation and prostaglandin secretion in porcine endometrium

45%
Kotwica G., Oponowicz A., Kurowicka B., Franczak A., Bogacka I.
Polish Journal of Veterinary Sciences
|
2010
|
tom 13
|
nr 4
We have studied in the porcine endometrium the expression of oxytocin receptor (OTR) mRNA and the effect of progesterone (P₄) on oxytocin/oxytocin receptor (OT/OTR) function concerning intracellular Ca²⁺mobilisation ([Ca²⁺]i), prostaglandin F2α (PGF2α) and E2 (PGE2; PG) secretion. Tissue was taken from cyclic and early pregnant pigs (days 14-16). A higher expression of OTR mRNA (P<0.05) was observed in the endometrium of cyclic than pregnant pigs. The stimulatory (P<0.05) effect of OT (10⁻⁷ M) on [Ca²⁺]i mobilisation was noticed within 15-60 s and 30-60 s in endometrial stromal cells of cyclic and pregnant pigs, respectively. In the presence of P₄ (10⁻⁵ M) basal and OT-stimulated [Ca²⁺]i concentrations decreased in stromal cells during luteolysis and pregnancy. In stromal cells P₄ delayed mobilisation of [Ca²⁺]i in response to OT by 15 s during luteolysis and had no effect during pregnancy. In cyclic and pregnant epithelial cells OT stimulated mobilisation of [Ca²⁺]i in 45 s and 60 s, respectively. Oxytocin increased (P<0.05) PGF2α secretion during luteolysis and pregnancy and PGE2 during luteolysis from endometrial slices. Progesterone did not inhibit this stimulatory effect. During luteolysis OT increased (P<0.05) PGF2α in epithelial and stromal cells and PGE2 secretion in epithelial cells. In the presence of P₄ this effect of OT was reduced only in stromal cyclic cells (6 h culture). The presence of P₄ decreased the effect of OT on [Ca²⁺]i mobilisation only in stromal cells. We found that, in most conditions, P₄ did not inhibit the OT-stimulated secretion of PG in the porcine endometrium.
15
Content available remote

In vitro effect of peroxisome proliferator activated receptor (PPAR) ligands on prostaglandin E2 synthesis and secretion by porcine endometrium during the estrous cycle and early pregnancy

45%
Bogacka I., Bogacki M., Gaglewska M., Kurzynska A., Wasielak M.
Journal of Physiology and Pharmacology
|
2013
|
tom 64
|
nr 1
16

The involvement of adenylyl cyclase and protein kinase A in the mechanism of opioid peptide action in porcine theca interna cells

45%
Kaminski T., Siawrys G., Bogacka I., Okrasa S., Przala J.
Cellular and Molecular Biology Letters
|
2002
|
tom 07
|
nr Suppl.
17
Content available remote

The influences of GnRH, oxytocin and vasoactive intestinal peptide on LH and PRL secretion by porcine pituitary cells in vitro

45%
Bogacka I., Siawrys G., Okrasa S., Kaminski T., Przala J.
Journal of Physiology and Pharmacology
|
2002
|
tom 53
|
nr 3
The aim of the present study was to evaluate the possible direct effects of GnRH, oxytocin (OT) and vasoactive intestinal peptide (VIP) on the release of LH and PRL by dispersed porcine anterior pituitary cells. Pituitary glands were obtained from mature gilts, which were ovariektomized (OVX) one month before slaughter. Gilts randomly assigned to one of the four groups were treated: in Group 1 (n=8) with 1 ml/100 kg b.w. corn oil (placebo); in Group 2 (n=8) and Group 3 (n=8) with estradiol benzoate (EB) at the dose 2.5 mg/100 kg b.w., respectively, 30-36 h and 60-66 h before slaughter; and in Group 4 (n=9) with progesterone (P4) at the dose 120 mg/100 kg b.w. for five consecutive days before slaughter. In gilts of Group 2 and Group 3 treatments with EB have induced the negative and positive feedback in LH secretion, respectively. Isolated anterior pituitary cells (106/well) were cultured in McCoy's 5a medium with horse serum and fetal calf serum for 3 days at 37°C under the atmosphere of 95% air and 5% CO2. Subsequently, the culture plates were rinsed with fresh McCoy's 5A medium and the cells were incubated for 3.5 h at 37°C in the same medium containing one of the following agents: GnRH (100 ng/ml), OT (10-1000 nM) or VIP (1-100 nM). The addition of GnRH to cultured pituitary cells resulted in marked increases in LH release (p<0.001) in all experimental groups. In the presence of OT and VIP we noted significant increases (p<0.001) in LH secretion by pituitary cells derived from gilts representing the positive feedback phase (Group 3). In contrast, OT and VIP were without any effect on LH release in Group 1 (placebo) and Group 2 (the negative feedback). Pituitary cells obtained from OVX gilts primed with P4 produced significantly higher amounts (p<0.001) of LH only after an addition of 100 nM OT. Neuropeptide GnRH did not affect PRL secretion by pituitary cells obtained from gilts of all experimental groups. Oxytocin also failed to alter PRL secretion in Group 1 and Group 2. However, pituitary cells from animals primed with EB 60-66 h before slaughter and P4 produced markedly increased amounts of PRL in the presence of OT. Neuropeptide VIP stimulated PRL release from pituitary cells of OVX gilts primed with EB (Groups 2 and 3) or P4. In contrast, in OVX gilts primed with placebo, VIP was without any effect on PRL secretion. In conclusion, the results of our in vitro studies confirmed the stimulatory effect of GnRH on LH secretion by porcine pituitary cells and also suggest a participation of OT and VIP in modulation of LH and PRL secretion at the pituitary level in a way dependent on hormonal status of animals.
18
Content available remote

The expression of short form of leptin receptor gene during early pregnancy in the pig examined by quantitative real time RT-PCR

45%
Bogacka I., Przala J., Siawrys G., Kaminski T., Smolinska N.
Journal of Physiology and Pharmacology
|
2006
|
tom 57
|
nr 3
The study was conducted to determine gene expression of short form of leptin receptor (OB-Rs) using real time RT-PCR in distinct tissues of the central nervous system (medial basal hypothalamus, preoptic area, stalk median eminence), pituitary and reproductive tract (corpus luteum, ovarian stroma, endometrium, myometrium, and trophoblast) in pigs during luteal phase of the cycle and early gestation. The expression of OB-Rs mRNA in SME did not differ between analyzed stages of the cycle and pregnancy. In anterior pituitary, transcript levels were almost identical in mid- and late-luteal periods, but significantly decreased on 30-32 day of gestation when compared with day 14-16. In posterior pituitary, significantly higher expression was observed in two periods of pregnancy when compared with two stages of luteal phase. In corpus luteum the lowest expression was observed during days 10-12 of the cycle, whereas markedly higher levels were detected in late-luteal stage and gestation. In ovarian stroma the expression of Ob-Rs mRNA was markedly diminished during days 14-16 of the cycle when compared with days: 10-12 of the cycle and 30-32 of pregnancy. The expression of Ob-Rs mRNA in endometrium and myometrium reached the lowest levels on 30-32 day of pregnancy in comparison with earlier stage, 14-16 day. Summarizing, the expression of the short form of leptin receptor mRNA was found in majority of tested tissues including hypothalamus, pituitary and reproductive tract and their levels fluctuated depending on the phase (mid- and late-luteal) of the cycle and the day of pregnancy (early and late stage of implantation).
19

Plasma glucocorticoids and ACTH levels during different periods of activity in the European beaver (Castor fiber L.)

39%
Czerwinska J., Chojnowska K., Kaminski T., Bogacka I., Panasiewicz G., Smolinska N., Kaminska B.
Folia Biologica
|
2015
|
tom 63
|
nr 4
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