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1

Porównanie metod immunoenzymatycznych stosowanych w monitorowaniu stężenia tacrolimusu we krwi pacjentów po transplantacji narządów

100%
Bartlomiejczyk I., Zochowska D., Matuszewicz D., Paczek L.
Diagnostyka Laboratoryjna
|
2007
|
tom 43
|
nr 3
2
Content available remote

Strong association between fibronectin accumulation and lowered cathepsin B activity in glomeruli of diabetic rats

100%
Wyczalkowska-Tomasik A., Bartolomiejczyk I., Gornicka B., Paczek L.
Journal of Physiology and Pharmacology
|
2012
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tom 63
|
nr 5
3

Mezenchymalne komorki macierzyste szpiku kostnego a starzenie

100%
Gala K., Burdzinska A., Paczek L.
Postępy Biologii Komórki
|
2010
|
tom 37
|
nr 1
89-106
4

Inflammatory markers change with age, but do not fall beyond reported normal ranges

100%
Wyczalkowska-Tomasik A., Czarkowska-Paczek B., Zielenkiewicz M., Paczek L.
Archivum Immunologiae et Therapiae Experimentalis
|
2016
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tom 64
|
nr 3
5

HPLC vs metoda immunochemiczna - wyniki badania korelacji metod oznaczania sirolimusa

100%
Zochowska D., Bartlomiejczyk I., Kaminska A., Paczek L.
Diagnostyka Laboratoryjna
|
2007
|
tom 43
|
nr 3
6

Myogenic stem cells

100%
Burdzinska A., Gala K., Paczek L.
Folia Histochemica et Cytobiologica
|
2008
|
tom 46
|
nr 4
401-412
7

TFX modulates the immunosuppressive effect of cyclophosphamide on antibody production in mice

88%
Paczek L., Gaciong Z., Gorski A., Lagodzinski Z., Brzezny M.
Archivum Immunologiae et Therapiae Experimentalis
|
1989
|
tom 37
|
nr 3-4
8
Content available remote

One session of exercise or endurance training does not influence serum levels of irisin in rats

88%
Czarkowska-Paczek B., Zendzian-Piotrowska M., Gala K., Sobol M., Paczek L.
Journal of Physiology and Pharmacology
|
2014
|
tom 65
|
nr 3
9

Poziom cytokin u pacjentów przewlekle dializowanych

88%
Bartlomiejczyk I., Gomolka M., Gerwatowska D., Niemczyk S., Paczek L.
Diagnostyka Laboratoryjna
|
2004
|
tom 40
|
nr 3
10

Selected clinical features fail to predict inflammatory gene expressions for TNF‑alpha, TNFR1, NSMAF, Casp3 and IL‑8 in tendons of patients with rotator cuff tendinopathy

88%
Struzik S., Czarkowska‑Paczek B., Wyczalkowska‑Tomasik A., Maldyk P., Paczek L.
Archivum Immunologiae et Therapiae Experimentalis
|
2021
|
tom 69
|
nr 1
11
Content available remote

The effects of indomethacin on angiogenic factors mRNA expression in renal cortex of healthy rats

88%
Mucha K., Foroncewicz B., Koziak K., Czarkowska-Paczek B., Paczek L.
Journal of Physiology and Pharmacology
|
2007
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tom 58
|
nr 1
Indomethacin is a nonsteroidal anti-inflammatory drug used frequently to control chronic or temporary pain. In the kidney, indomethacin decreases medullary and cortical perfusion, resulting in hypoxia. Kidney hypoxia has many effects, including changes in gene expression, and is a strong stimulus for angiogenesis. Other angiogenic factors include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (FGF-2), transforming growth factor beta 1 (TGFß1), and platelet-derived growth factor (PDGF). Our goal was to examine the influence of indomethacin on mRNA expression of these factors and their selected receptors in the renal cortex of healthy rats. Groups of 8 healthy, male, six-week-old Wistar rats received either indomethacin (5 mg/kg/day) or placebo orally for three months. RNA from renal cortex biopsies was analyzed by real-time polymerase chain reaction to quantify the mRNA levels of each cytokine. We observed significantly higher mRNA levels for VEGF (1.73-fold), FGF-2 (5.6-fold) and TGFß receptor III (2.93-fold), PDGF receptor alpha (2.93-fold) and receptor ß (2.91-fold) in rats receiving indomethacin compared to rats given placebo (p < 0.05). Amounts of mRNA for TGFß1, PDGF, FGF receptors 1 and 2 and TGFß receptor I did not differ between analysed groups. Our data indicates that indomethacin may regulate the expression of potent angiogenic factors VEGF and FGF-2.
12

Porównanie metod immunologicznych EMIT i CMIA - oznaczanie stężenia tacrolimusu we krwi pacjentów po przeszczepieniu nerki lub wątroby. Doniesienie wstępne

76%
Bartlomiejczyk I., Wirkowska A., Wyczalkowska-Tomasik A., Garlinska M., Gala K., Paczek L.
Diagnostyka Laboratoryjna
|
2010
|
tom 46
|
nr 4
13

Involvement of beta2-microglobulin in CD69 expression on T cells

76%
Paczek L., Czarkowska-Paczek B., Korczak-Kowalska G., Wierzbicki P., Bartlomiejczyk I., Gorski A.
Archivum Immunologiae et Therapiae Experimentalis
|
2001
|
tom 49
|
nr 3
239-242
14
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The first investigation on differences in the effectiveness of mycophenolate mofetil and azathioprine antimetabolites determined in Polish patients treated for non-infectious uveitis

76%
Waszczyk-Laczak M., Lazicka-Galecka M., Chomicz L., Mucha K., Paczek L., Szaflik J. P.
Annals of Agricultural and Environmental Medicine
|
2020
|
tom 27
|
nr 4
15

Bacteriological urinalysis in patients after renal transplantation

76%
Lazinska B., Ciszek M., Rokosz A., Sawicka-Grzelak A., Paczek L., Luczak M.
Polish Journal of Microbiology
|
2005
|
tom 54
|
nr 4
The study consisted of microbiological urinalysis performed in 269 patients after renal transplantation who remained under medical care at the Outpatient Service of the Transplantation Institute in Warsaw. The patients enrolled into the study had undergone renal transplantation 6 to 72 months before urine samples were collected. 304 urinalysis were performed. In the group of 269 patients, 42 individuals had bacteria in their urine what was confirmed in 47 urine cultures. Cases of bacteriuria were divided into 5 groups: 5 cases of symptomatic urinary tract infection (5 individuals - 2% of all studied patients), 27 cases of asymptomatic bacteriuria in 22 individuals (8% of all studied patients), 5 cases of insignificant bacteriuria in 5 patients (2%), 10 cases of involuntary urine contamination in 10 cases (4%). Eventually, urinary tract infection (UTI) was established in 27 patients (5 cases of symptomatic UTI and 22 cases of asymptomatic UTI) what makes out for 10% of all studied patients. In cases where urinalysis showed significant bacteriuria, following pathogens were detected in urine cultures: Escherichia coli: 22 strains, Enterococcus faecalis - 4 strains, Enterobacter cloacae - 2 strains and 1 strains of Ralstonia picketii, Streptococcus uberis, Pseudomonas aeruginosa and Proteus mirabilis. Over 90% of Gram-negative bacteria were susceptible to ceftriaxone and ceftazidime, as well as to amikacin and aztreonam which are the drugs usually administered intravenously in hospitalized patients. The only drug of similar efficacy, which could be administered orally in outpatients was fosfomycin.
16

Identification of cytomegalovirus [CMV] infection by different laboratory methods in renal transplant recipients undergoing triple-drug immunosupressive treatment

64%
Siennicka J., Durlik M., Litwinska B., Chmura A., Lewandowska D., Lao M., Paczek L., Kantoch M.
Acta Microbiologica Polonica
|
1999
|
tom 48
|
nr 1
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