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Blind mole rat (Spalax leucodon) masseter muscle: structure, homology, diversification and nomenclature

100%

Yoldas A., Demir M., Ilgun R., Dayan M. O.

Folia Morphologica

2019

tom 78

nr 2

Background: It is well known that rodents are defined by a unique masticatory apparatus. The present study describes the design and structure of the masseter muscle of the blind mole rat (Spalax leucodon). The blind mole rat, which emerged 5.3–3.4 million years ago during the Late Pliocene period, is a subterranean, hypoxia-tolerant and cancer-resistant rodent. Yet, despite these impressive characteristics, no information exists on their masticatory musculature. Materials and methods: Fifteen adult blind mole rats were used in this study. Dissections were performed to investigate the anatomical characteristics of the masseter muscle. Results: The muscle was comprised of three different parts: the superficial masseter, the deep masseter and the zygomaticomandibularis muscle. The superficial masseter originated from the facial fossa at the ventral side of the infraorbital foramen. The deep masseter was separated into anterior and posterior parts. The anterior part of the zygomaticomandibularis muscle arose from the snout and passed through the infraorbital foramen to connect on the mandible. Conclusions: The construction of the deep masseter and zygomaticomandibularis muscles were of the Myomorpha type. Further studies are needed to reveal features such as muscle biomechanics, muscle types. (Folia Morphol 2019; 78, 2: 419–424)

Comparison of type I collagens and MMP-2 proteins in temporomandibular joint of young and old mice

76%

Demir M., Tumer M. K., Cicek M., Uysal M., Yoldas A., Doganer A.

Folia Morphologica

2018

tom 77

nr 2

Background: The effects of ageing on the histopathological changes of temporomandibular joint (TMJ) and the existence and age related alterations of immunochemical expressions of type I collagen and matrix metalloproteinase-2 (MMP-2) proteins was aimed to be displayed. Materials and methods: In this study, 14 Balb/C type white mice (50–80 g) were included. Groups were organised as group 1 — 2-month-old young animals (n = 7) and group 2 — 18-month-old old animals (n = 7). Of the paraffin embedded tissues 4–5 µm thick sections were taken and immunohistochemical stainings of haematoxylin-eosin, type-1 collagen and MMP-2 were performed. Results: Collagen bundles showed sagittal and oblique localisations in the young mice, which were comprised of compact collagen bundle layers positioned alternately. While collagen bundle fragmentation was observed in the disks of old mice, some disk regions showed ruptures. In the old mice a decrease in blood vessels, structural impairments and dilatation in arterioles and venules were detected. In the TMJ tissues of the young mice type I collagen and MMP-2 expressions were increased, while they were decreased in old mice. In the MMP-2 H-score evaluation young mice showed significant increase compared to the old mice. Conclusions: Occurrence of degenerations in the collagen structure of TMJ and decimation in the matrix metalloproteases were observed with age. (Folia Morphol 2018; 77, 2: 329–334)

Ograniczanie wyników

2 Folia Morphologica

2 Demir M.

2 Yoldas A.

1 Cicek M.

1 Dayan M. O.

1 Doganer A.

1 Ilgun R.

1 Tumer M. K.

1 Uysal M.

1 2019

1 2018

Wyniki wyszukiwania

Blind mole rat (Spalax leucodon) masseter muscle: structure, homology, diversification and nomenclature

Comparison of type I collagens and MMP-2 proteins in temporomandibular joint of young and old mice