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The rules of aging: are they universal? Is the yeast model relevant for gerontology?

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Bilinski T., Zadrag-Tecza R.

Acta Biochimica Polonica

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2014

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tom 61

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nr 4

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The links between hypertrophy, reproductive potential and longevity in the Saccharomyces cerevisiae yeast

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Molon M., Zadrag-Tecza R.

Acta Biochimica Polonica

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2016

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tom 63

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nr 2

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Dependence of the yeast Saccharomyces cerevisiae post-reproductive lifespan on the reproductive potential

80%

Zadrag-Tecza R., Molon M., Mamczur J., Bilinski T.

Acta Biochimica Polonica

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2013

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tom 60

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nr 1

The lifespan of budding yeast cells is divided into two stages: reproductive and post-reproductive. The post-reproductive stage of the yeast's lifespan has never been characterized before. We have analyzed the influence of various mutations on the post-reproductive (PRLS) and replicative (RLS) lifespans. The results indicate that PRLS demonstrates an inverse relationship with RLS. The observed lack of differences in the total lifespan (TLS) (expressed in units of time) of strains differing up to five times in RLS (expressed in the number of daughters formed) suggests the necessity of revision of opinions concerning the use of yeast as a model organism of gerontology.

Ograniczanie wyników

3 Acta Biochimica Polonica

3 Zadrag-Tecza R.

2 Bilinski T.

2 Molon M.

1 Mamczur J.

1 2016

1 2014

1 2013

The rules of aging: are they universal? Is the yeast model relevant for gerontology?

The links between hypertrophy, reproductive potential and longevity in the Saccharomyces cerevisiae yeast

Dependence of the yeast Saccharomyces cerevisiae post-reproductive lifespan on the reproductive potential