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1

Nitric oxide (NO) and central dopamine (DA) receptors reactivity in rats

100%
Brus R., Szkilnik R., Nowak P., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
|
1995
|
tom 55
|
nr 5
2

Reactivity of the central dopamine (DA) receptors in rats prenatally exposured to selenium

100%
Szkilnik R., Kwiecinski A., Nowak P., Brus R.
Acta Neurobiologiae Experimentalis
|
1999
|
tom 59
|
nr 3
3

The diuretic action of noradrenaline and dopamine in rats with chemical serotoninectomy and central nervous system sympathectomy

100%
Brus R., Szkilnik R., Stanosek B., Herman Z. S.
Acta Physiologica Polonica
|
1983
|
tom 34
|
nr 3
4

The concentration of gamma-aminobutyric acid ( Gaba) in discrete areas of rat brain after chemical sympathectomy or serotoninectomy

100%
Szkilnik R., Brus R., Herman Z. S.
Acta Physiologica Polonica
|
1980
|
tom 31
|
nr 5
5

Nitric oxide (NO) and central effects of the dopamine (DA) agonists on circulatory system in rats

100%
Nowak P., Brus P., Kasperska A., Szkilnik R.
Acta Neurobiologiae Experimentalis
|
1997
|
tom 57
|
nr 5
6

Effect of combined cadmium and ethanol prenatal exposure on biogenic amines level and release in the brain after haloperidol apply in adult offspring rats in vivo microdialyses study

100%
Szkilnik R., Nowak P., Brus R., Labus L.
Acta Neurobiologiae Experimentalis
|
2001
|
tom 61
|
nr 3
7

Effect of the central dopamine and serotonin receptor agonist on biogenic amines release in rats brain with experimental model of attention deficit hyperactivity disorder (ADHD) in vivo brain microdialysis study

100%
Nowak P., Brus R., Szkilnik R., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
|
2001
|
tom 61
|
nr 3
8

Effect of L-Name and L-Arginine on irritability and aggressivity after central dopamine agonists apply in 5,7-DHT and 6-OHDA - neonatally lesioned rats

100%
Kasperska A., Oswiecimska J., Szkilnik R., Brus R.
Acta Neurobiologiae Experimentalis
|
1997
|
tom 57
|
nr 5
9

Nitro-l-arginine attenuates SKF 38393 - induced oral activity in neonatal 6-hydroxydopamine-lesioned rats

100%
Brus R., Szkilnik R., Nowak P., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
|
1997
|
tom 57
|
nr 4
10

Nitric oxide [NO] and central dopamine [DA] D3 receptor reactivity to quinpirole in rats

100%
Brus R., Szkilnik R., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
|
1996
|
tom 56
|
nr 1
11

Effect of combined cadmium and ethanol prenatal exposure on internal organs and biogenic amines levels in the brains of rat offspring

100%
Szkilnik R., Felinska W., Nowak P., Brus R.
Polish Journal of Environmental Studies
|
1997
|
tom 06
|
nr 1
Ethanol (EtOH) abuse in pregnancy is known to produce serious damage to internal organs of the fetus, a condition in humans that is classified as "fetal alcohol syndrome". Cadmium (Cd), a heavy metal pollutant of the environment, represents another toxin that produces retarded fetal growth and teratogenic effects. The developing brain is particularly sensitive to both toxins, being affected morphologically and neurochemically. Besides prenatal EtOH and Cd have been found to reduce endogenous dopamine (DA) levels and turnover in the brain and change reactivity of the central DA receptors to agonists. To test effect of separate and joint applications of the above xenobiotics on offspring during pregnancy, rats were given 10% (v/v) EtOH and/or Cd (5 or 50 ppm) in their drinking water. Numbers of pregnant rats, newborns in the litter, birth body mass, and the number of offspring surviving 3 weeks after birth were recorded. Then in 6-week-old offspring the anatomopathological study of internal organs, and the level of biogenic amines (NA, 5-HT, 5-HIAA) in the discrete parts of the brain were estimated spectrofluorometrically. Prenatal exposure to EtOH prevents some toxic effect of Cd in rat offspring (morphological, condition of offspring). On the other hand, EtOH intensified some effects of Cd on the biogenic amines level in the brain.
12

Effect of prenatal cadmium and ethanol exposure on the duration of ethanol - induced sleep in female and male rats

100%
Szkilnik R., Felinska W., Brus R.
Polish Journal of Environmental Studies
|
1994
|
tom 03
|
nr 3
Female adult Wistar rats were given tap warter (control), 10% (v/v) water solution of ethanol and/or cadmium (5 or 50 ppm) in tap water or in 10% ethanol ad libitum throughout their pregnacies. As soon as the offspring were born, the administration of all above solutions was discontinued and all females began drinking water only. Adult female and male offspring from each group were challenged with a single hypnotic dose of ethanol (3.5 g/kg IP) in the form of 20% (v/v) water solution. The latency from the time of injection until the loss of the righting reflex, as well as the latency for recovery of the reflex was recorded. The results showed that female rats exposed to cadmium after ethanol 3.5 g/kg IP challenge lose the righting reflex rapidly and recovery of it was later as compared to control animals. In female rats exposed during intrauteral development to cadmium jointly with ethanol measured parameters return to values as in the control group. No statistically significant differences in loss and recovery of the righting reflex in all groups of male rats after the ethanol 3.5 g/kg IP challenge was recorded.
13

Effect of the aminoacid L-Arginine and its analog Nitro-L-Aginine methyl ester HCl (L-Name) on central dopamine (DA) receptor reactivity

88%
Brus R., Szkilnik R., Kasperska A., Oswiecimska J., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
|
1997
|
tom 57
|
nr 5
14

Glucose uptake in the brain of rats after administration of quinpirole and 7-OH-DPAT, two central, dopamine (DA) receptors agonists

88%
Brus R., Oswiecimska J., Szkilnik R., Konecki J., Shani J.
Acta Neurobiologiae Experimentalis
|
1999
|
tom 59
|
nr 3
15

Central action of melanostatin (MIF-1) in mice

88%
Brus R., Szkilnik R., Stanosek B., Makowska B., Pigula J.
Acta Physiologica Polonica
|
1984
|
tom 35
|
nr 5-6
16

Comparison DOPAC release in the striatum and some behavioral effects of quinpirole and 7-OH-DPAT, the dopamine D2/D3 receptors agonists in rats

88%
Brus R., Oswiecimska J., Szkilnik R., Sokola A., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
|
1999
|
tom 59
|
nr 3
17

Effects of intrahypothalamic injections of kainic acid on the bahaviour of rats

88%
Plech A., Szkilnik R., Zielinski M., Klis R., Herman Z. S.
Acta Physiologica Polonica
|
1981
|
tom 32
|
nr 2
18

In vivo voltammetric determination of the enhanced spiperone - induced release of dopamine (DA) and dihydroxyphenylacetic acid (DOPAC) in neostriatum of rats with supersensitized DA D2-receptors

88%
Brus R., Kostrzewa R. M., Jedrusiak J., Szkilnik R., Wojtowicz L.
Acta Neurobiologiae Experimentalis
|
1995
|
tom 55
|
nr 5
19

Effect of cadmium applied jointly with diazepam to pregnant rats on the central dopamint (DA) receptor reactivity and glucose uptake in the brain and pefuferal tissues of offsprings

76%
Brus R., Szkilnik R., Nowak P., Sawczuk N. K., Konecki J., Shani J.
Acta Neurobiologiae Experimentalis
|
1997
|
tom 57
|
nr 5
20

5-hydroxydopamine unspecific centrally acting false neurotransmitter

76%
Brus R., Herman Z. S., Szkilnik R., Dzikowski A., Opielka L., Bonczek A.
Acta Physiologica Polonica
|
1977
|
tom 28
|
nr 1
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