In considering Gdańsk’s environmental problems not only environmental hazards but also nuisances to the residents are taken into account: poor municipal infrastructure, roads, heating network, natural gas supply system, water pipes, and stormwater and sanitary systems. Problems specific to Gdańsk are exemplified by revitalisation of old districts in the city centre, where industrial activity has been abandoned and which can be used for other purposes, while preserving their cultural values.
Kopeć, J.: Methodological survey of automatic EMG analysis. Acta physiol, pol., 1988, 39(1): 20-29. This paper describes a methodological survey of different methods, manual and computer-aided for quantitative MUP analysis up to the present. Due to different recording techniques and facilities for signal analysis individual laboratories have developed their own methods. Although most of the methods are still in the research phase, they provide a valuable contribution to clinical possibilities. The most important effect of the computer in electromyography is the fact that it emphasizes a new trend in quantitative EMG analysis also in routine clinical assessment.
Cervical carcinogenesis is a complex problem with papillomavirus widely accepted as a causative agent. Integration of a human papillomavirus (HPV) of the high-risk type into the host cell genome is one of the major contributing factors to cervical malignant transformation. In this study, the correlation of CMV, EBV, HSV-1, HSV-2, HHV-6 and HHV-7 infections with the physical status of the HPV genome in cervical cancer and precancerous cervical lesions was investigated in sixty HPV-16-positive women. Cervical secretion samples were submitted to DNA extraction and analyzed by PCR. HPV-16 DNA was confirmed in genotyping with the reverse hybridization line probe assay. Multiplex PCR with specific primers for the E2/E6 genes was used to assess the viral integration status of HPV-16. Our results show that CMV DNA was more frequently present in samples with mixed forms of HPV-16 than in the episomal form (P < 0.025). Such a correlation was also observed in the case of EBV (P < 0.005). The presence of CMV resulted in a six-fold (OR 6.069; 95% CI 1.91-19.22; P = 0.002), while EBV caused a seven-fold (OR 7.11; 95% CI 1.70-29.67; P = 0.007) increase in the risk of the integrated or mixed HPV-16 genome occurrence. Our data suggest that coinfection with herpesviruses, especially CMV and EBV, may be involved in the integration of the HPV-16 genome and may contribute to the development of cervical cancer.