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1
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Propozycje Komitetu Parazytologii Wydzialu Nauk Biologicznych PAN dot. standardow nauczania w zakresie parazytologii na uczelniach w Polsce

100%
Kurnatowski P.
Wiadomości Parazytologiczne
|
2010
|
tom 56
|
nr 3
223-230
2
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Prof. zw. dr med. kanad. n. med. Roscislaw Kadlubowski [1921-2009] - pro memoriam

100%
Kurnatowski P.
Wiadomości Parazytologiczne
|
2010
|
tom 56
|
nr 1
87-88
3
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Selected host response reactions to fungal or parasite invasion

100%
Kurnatowski P.
Wiadomości Parazytologiczne
|
1998
|
tom 44
|
nr 3
4
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Niektore aspekty grzybic wieloogniskowych i uogolnionych

88%
Kurnatowski P.
Wiadomości Parazytologiczne
|
2004
|
tom 50
|
nr 3
359-365
5
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Metody diagnostyki laboratoryjnej stosowane w mikologii

63%
Kurnatowska A., Kurnatowski P.
Wiadomości Parazytologiczne
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2008
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tom 54
|
nr 3
177-185
6
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Biofilm tworzony przez grzyby - struktura, quorum sensing, zmiany morfogenetyczne, opornosc na leki

63%
Nowak M., Kurnatowski P.
Wiadomości Parazytologiczne
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2009
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tom 55
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nr 1
19-25
7
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Secretion of hydrolytic enzymes by fungal strains, isolated from patients with malignant tumors of head and neck, before, during and after radiotherapy

63%
Moqbil S., Kurnatowski P.
Annals of Parasitology
|
2012
|
tom 58
|
nr 1
One method of treatment used in cancer therapy is radiotherapy which can injure the oral, pharynx or larynx mucosa and predisposes tissue to the development of fungal infections. The aim of the study paper was the mycological examinations of swabs from the oral cavity and pharynx of patients obtained prior to, in week 3, on the last day of and 3 weeks after radiotherapy, as well as isolation of fungi and identification of the selected parameter of strains pathogenecity, i.e. hydrolytic enzyme release. Forty-three patients with oral cavity, pharynx or larynx carcinoma were examined at four points during a course of radiotherapy: before treatment, in week 3 of treatment, on the last day of treatment and 3 weeks afterwards. The mycological examination was conducted based on a procedure introduced in the Department of Biology and Medical Parasitology, Medical University of Lodz. The activity of the hydrolytic enzymes was evaluated with a bioMerieux API ZYM test kit. More than 2/3 of the patients (68.2%) were found to have a fungal infection in the first examination, 4/5 (80%) in the second, about 3/5 (57.1%) in the third and all (100%) in the last examination. The release of enzymes varied, and on different stages show different inactive enzymes: at the start, α-chymotrypsin and α-mannosidase; at 3 weeks, β-glucuronidase and α-mannosidase; at the end, α-chymotrypsin; at 3 weeks after the end, trypsin, α-chymotrypsin, α-galaktosidase and α-fucosidase. The most frequent species isolated from the patients treated by radiotherapy is Candida albicans and C. glabrata. The latter is characterized by resistance to the majority of antimycotic medications. The isolated strains are characterized by the highest activity of leucine arylamidase, acid phosphatase and naphthol – AS-BI-phosphohydrolase. Considering the enzymes produced, most of the strains can be included to biotypes D₃, C₆ and A.
8
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Adherence of Candida sp. to host tissues and cells as one of its pathogenicity features

63%
Modrzewska B., Kurnatowski P.
Annals of Parasitology
|
2015
|
tom 61
|
nr 1
The ability of Candida sp. cells to adhere to the mucosal surfaces of various host organs as well as synthetic materials is an important pathogenicity feature of those fungi which contributes to the development of infection. This property varies depending on the species of the fungus and is the greatest for C. albicans. The process of adhesion depends on plenty of factors related to the fungal and host cells as well as environmental conditions. The main adhesins present on the fungal cell wall are: Als, Epa, Hwp1, but also Eap1, Sun41, Csh1 and probably Hyr1; for adhesion significant are also secreted aspartyl proteases Sap. Various researchers specify a range of genes which contribute to adhesion, such as: CZF1, EFG1, TUP1, TPK1, TPK2, HGC1, RAS1, RIM101, VPS11, ECM1, CKA2, BCR1, BUD2, RSR1, IRS4, CHS2, SCS7, UBI4, UME6, TEC1 and GAT2. Influence for adherence have also heat shock proteins Hsp70, Mediator Middle domain subunit Med31 and morphological transition. Among factors affecting adhesion related to host cells it is necessary to mention fibronectins and integrins (receptors for Candida sp. adhesins), type of epithelial cells, their morphology and differentiation phase. To a lesser degree influence on adhesion have nonspecific factors and environmental conditions.
9
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The in vitro activity of selected mouthrinses on standard strains of fungi

63%
Moroz J., Kurnatowski P.
Annals of Parasitology
|
2017
|
tom 63
|
nr 4
An oral cavity hygiene plays a key role in prophylactic and therapeutic measures to prevent pathological changes caused by different viruses, bacteria, fungi and protozoa. It is important to maintain proper oral hygiene and assist the removal of potent pathogens; use of the mouthrinses can be one of method providing to these goal. The purpose of this study was to investigate the effects of selected mouthrinses on the standard strains of Candida presented in the oral cavity. Eight reference strains of fungi were investigated: C. albicans (CBS 2312), C. albicans (L 45), C. albicans (ATCC 24433), C. dubliniensis (CBS 7987), C. glabrata (CBS 862), C. krusei (CBS 573), C. parapsilosis (CBS 10947) and C. tropicalis (CBS 2424). Thirteen mouthrinses were used in the study, including pure chlorhexidine (CHX), and 12 commercially available varieties: Azulan, Colgate Plax Complete Care Sensitive, Corsodyl 0,2%, Curasept ADS 205, Dentosept, Dentosept A, Eludril Classic, Listerine Total care, Octenidol, Oral-B Pro-Expert Clinic Line, Sylveco and Tinctura salviae. The present study used a qualitative diffusion in agar gel-well plate method to evaluated the antifungal properties of mouthrinses. Among the 12 commercially available mouthrinses examined in the study, the following were not found to show antifungal activity: Azulan, Dentosept, Eludril Classic, Listerine Total care, Tinctura salviae. The largest inhibition zones were produced by Dentosept, Chlorhexidine and Colgate. The smallest inhibition zones were produced by Octenidol and Curasept. With regard to mouthwash type, statistically significant differences in growth inhibition zone diameter were found between the following pairs of fungi: C. albicans and C. krusei for Colgate without dilution and with 1:2 dilution; C. albicans and C. glabrata for Corsodryl without dilution and with 1:2 dilution; C. albicans and C. dubliniensis for Dentosept A without dilution; C. glabrata and C. parapsilosis with 1:2 dilution; C. dubliniensis and C. tropicalis for Sylveco without dilution, 1:2 dilution and 1:4 dilution; C. dubliniensis and C. parapsilosis for Sylveco without dilution, 1:2 dilution and 1:4 dilution. The lowest MIC values calculated from the Iinear regression equation, indicating the strongest potential activity, were obtained for Dentosept A, followed by chlorhexidine; the lowest activity, was calculated for Curasept and for Octenidol. Some of the tested mouthrinses have antimycotic properties at commercially available concentrations. In spite of the fact that chlorhexidine is thought to be the gold standard for mouthrinse use, Dentosept has stronger antimycotic activity and acts on a wider spectrum of fungi species. Chlorhexidine and Colgate do not appear to act against C. tropicalis, neither does Curaspet against C.dubliniensis; therefore, the determination of the fungus species is necessary.
10
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Grzyby jako czynnik etiologiczny chorob gornych drog oddechowych

63%
Kurnatowski P., Raczynska-Witonska G.
Wiadomości Parazytologiczne
|
2004
|
tom 50
|
nr 2
157-162
11
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Metody diagnostyki stosowane w mikologii

63%
Kurnatowski P., Kurnatowska A.
Wiadomości Parazytologiczne. Suplement
|
2007
|
tom 53
202
12
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Wybrane czynniki sprzyjajace zarazeniom grzybami w populacji czlowieka

63%
Kurnatowski P., Tyczkowska-Sieron E.
Wiadomości Parazytologiczne
|
2004
|
tom 50
|
nr 3
367-372
13
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Otitis externa: the analysis of relationship between particular signs-symptoms and species and genera of identified microorganisms

63%
Kurnatowski P., Filipiak J.
Wiadomości Parazytologiczne
|
2008
|
tom 54
|
nr 1
37-41
14
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Rzesistkowica jamy ustnej powiklana grzybica [trichomonosomycosis]

63%
Kurnatowska A. J., Kurnatowski P.
Wiadomości Parazytologiczne
|
1999
|
tom 45
|
nr 2
129-133
Protozoa and fungi of the oral cavity, although frequently occuring and connected with considerable clinical adverse effects, are as yet insufficiently known. The aims of the study were to estimate the prevalence of common invasions of Trichomonas tenax and fungi, to associate the symptoms with the diagnosis of trichomonosis complicated by mycosis and to determine trichomonacidal properties of ornidazole, tinidazole and metronidazole. 936 dentist patients with different diagnoses were included into the study. The collected material consisted of rinsings, with simultaneous application of selective media, different for protozoa and for fungi cultures. Among the examined patients T. tenax was found in 90 cases including 85 cases where it occurred together with fungi (11 species), on the basis of which the diagnosis of trichomonosomycosis of the oral cavity was established. It was the most often in patients with leukoplakia and Lichen Wilsoni. We received a statistically significant association (0.001
15
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Parasites as etiological factors of nosocomial infections

63%
Goralska K., Kurnatowski P.
Annals of Parasitology
|
2013
|
tom 59
|
nr 1
Nosocomial infections represent an increasing threat to public health. In most cases, they concern patients with risk factors such as taken radio- and chemotherapy, those whose immune system might be suppressed and those who might be HIV-positive. Most studies of the incidence of nosocomial infections ignore parasitic infestations. Based on data from 1,265 intensive care units in 75 countries, it was found that the proportion of parasites in nosocomial infections was 0.48% overall, and 0.25% in Western Europe. An analysis of the available literature indicates an increase in the number of hospital parasitoses.
16
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Selected pathogenic characteristics of fungi from the genus Candida

63%
Modrzewska B., Kurnatowski P.
Annals of Parasitology
|
2013
|
tom 59
|
nr 2
The prevalence of fungi from the genus Candida in humans is increasing, but the mere fact of their detection does not allow, in general, to diagnose a disease. In fact the development of fungal infection depends on several factors of the host-pathogen relationship. The occurrence of symptoms and the course of the disease are associated, inter alia, with general and immunological conditions of an infected person as well as the properties of strains. Differences between the strains responsible for asymptomatic and symptomatic invasion have been shown. Thus the determination of their pathogenicity parameters is an important element leading to proper identification, both mycological and clinical, which allows for the implementation of therapeutic intervention. There are several virulence factors that are essential for surviving in host’s organism and play important role in each phase of fungal infection. This review provides an update on selected pathogenicity features: formation of hyphae and/or pseudohyphae, phenotypic switching, tropic reactions and biofilm production.
17
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Comparative analysis of morphometric features of the eggs of selected alimentary tract parasites and of the plant pollens

63%
Szwabe K., Kurnatowski P.
Annals of Parasitology
|
2012
|
tom 58
|
nr 2
The aims of the study were: 1. to compare morphometric features of eggs of selected alimentary tract parasites and common garden plants pollen, which may accidentally contaminate a feces undergoing parasitological examination; 2. to make laboratory diagnosticians aware of a possibility of an error at coproscopic examination as well as in helminthologic evaluation of the environmental samples (soil, water). Eggs of 7 species of alimentary tract parasites and 52 common garden plants pollens were examined and compared; using of MultiScanBase v.8.08 computer program the perimeter, length and width of the given objects/images were measured and statistical calculations were made in Statistica 9.1 program. The following conclusions can be drawn: 1. The computer image comparative analysis of parasite eggs and plant pollen proved the existence of statistically significant differences between the particular morphometric features; 2. A routine direct microscopic observation of feces is performed with the naked eye which is not able to notice slight differences (up to a few μm in size), and therefore, despite lack of statistically significant differences, it is easy to make an error; 3. During a routine microscopic observation it should be remembered that the structure, shape or exine of many commonly occurring pollen grains are extremely similar to eggs of some parasites; 4. Both in the analysis of feces specimens and the evaluation of environmental samplings characteristic morphological features of eggs should be considered to facilitate differentiation between eggs and pollen grains; 5. Following the precautionary measures to avoid contamination of feces simples with plants pollens, quality control as well as reliability and awareness of risk eliminates danger of obtaining false positive results.
18
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Odpowiedz immunologiczna na zarazenie grzybami

63%
Kurnatowski P., Kurnatowska A. J.
Wiadomości Parazytologiczne
|
2010
|
tom 56
|
nr 1
23-27
19
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Some aspects of host-fungus interactions

63%
Kurnatowski P., Kurnatowska A. J.
Wiadomości Parazytologiczne
|
2001
|
tom 47
|
nr 4
20
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Trichomonosomycosis of the oral cavity

63%
Kurnatowska A. J., Kurnatowski P.
Wiadomości Parazytologiczne
|
1998
|
tom 44
|
nr 3
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