Wyniki wyszukiwania

1

Psoraleny jako narzędzia w badaniu struktury i funkcji kwasów nukleinowych

100%

Czyz M.

Postępy Biochemii

|

1989

|

tom 35

|

nr 4

2

Specyficznosc i selektywnosc dzialania czynnika transkrypcyjnego NFkB

100%

Czyz M.

Postępy Biochemii

|

2005

|

tom 51

|

nr 1

60-68

3

Ryzyko w sferze inwestycji proekologicznych

75%

Czyz M.

Ekonomia i Środowisko

|

2002

|

nr 1

93-105

4

Metody analizy uwarunkowan ekologicznych wzrostu gospodarczego

75%

Czyz M.

Człowiek i Przyroda

|

1998

|

nr 08-09

159-164

5

Reaction of lime trees (Tilia sp.) growing along the Zwirki i Wigury Street in Warsaw on soil salinity caused by chemical technology of snow removal

63%

Kwasowski W., Czyz M.

Ecological Questions

|

2011

|

tom 14

The studies were focused on the influence of sodium chloride application in the chemical technology of snow removal from streets on the conditions of lime trees (Tilia sp.) growing along the Żwirki i Wigury Street in Warsaw and the determination of the degree of salinity on soils under street vegetation. The analyses show that chemical technology of soil removal causes changes in the soil environment. They include ionic imbalance of the soil solution and change of soil reaction. Electrical conductivity of the saturated soil extract also increases, as well as content of soluble salts in soils under street vegetation. Sodium chloride significantly influences the lime trees growing along the Żwirki i Wigury Street. Leaves growing directly near the street show severe effects of paralysis by sodium chloride in form of necrosis, discoloration (browning), and in consequence drying and premature leaf-fall.

6

New locality of vulnerable bivalve species Pisidium obtusale (Lamarck, 1819) (Sphaeriidae) with notes on its ecology and conservation status in Wielkopolska region (western Poland)

63%

Czyz M., Nizio J.

Badania Fizjograficzne. Seria C - Zoologia

|

2010

|

tom 01(C51)

7

Preliminary metrological study of the lumbar vertebral column during the foetal period

63%

Czyz M., Kedzia A.

Folia Morphologica

|

2003

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tom 62

|

nr 3

259-262

The aim of our study was to elaborate a scheme for the development of the particular elements of the lumbar vertebral column in the foetal period based on metrological data analysis. 30 human foetuses between 31 and 183 mm C-R length were examined. The whole vertebral column and lumbar segment length, intervertebral spaces and structural elements of each vertebra were measured. Statistical analysis was carried out of the data obtained. The development of the lumbar vertebral column during the foetal period is ongoing, although not in a proportional way. The percentage participation of the lumbar segment in the length of the whole vertebral column increased from 17.5 to 22%. The most intensive development of the particular elements resulted from the period between 60–170 mm. The intensive transversal growth of each vertebra began after 60 mm while the axial growth began after 110 mm CRL. The percentage participation of a single lumbar vertebra in the length of the whole lumbar segment decreased by approx. 5%. The largest contribution to the ossification centres was made in the areas of neural arches L1. Each structural element and the diameter of each lumbar vertebra is characterised by specific growth dynamics.

8

Transcription factors as targets of anticancer drugs

63%

Gniazdowski M., Czyz M.

Acta Biochimica Polonica

|

1999

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tom 46

|

nr 2

Several general and gene- and cell-selective transcription factors are required for specific transcription to occur. Many of them exert their functions through specific contacts either in the promoter region or at distant sequences regulating the initiation. These contacts may be altered by anticancer drugs which form non-covalent complexes with DNA. Covalent modifications of DNA by alkylating agents may prevent transcription factors from recognizing their specific sequences or may constitute multiple "unnatural" sites in DNA which attract the factors thus decreasing their availability in the cell. The anticancer drug-transcription factor interplay which is based on specific interactions with DNA may contribute to pharmacological properties of the former and provide a basis for the search for new drugs.

9

Actinomycin D specifically inhibits the interaction between transcription factor Sp1 and its binding site

63%

Czyz M., Gniazdowski M.

Acta Biochimica Polonica

|

1998

|

tom 45

|

nr 1

The mode of action of many anticancer drugs involves DNA interactions. We here examine the ability of actinomycin D to alter the specific binding of transcription factors Sp1 and NFκB to their DNA sequences. Employing an electrophoretic mobility shift assay, it is shown that actinomycin D inhibits complex formation between nuclear proteins present in the extracts from stimulated human umbilical vein endothelial cells and the Sp1-binding site. Actinomycin D is also able to induce disruption of preformed DNA-protein complexes, pointing to the importance of an equilibrium of three components: actinomycin D, protein and DNA for drug action. The effect of actinomycin D is sequence-specific, since no inhibition is observed for interaction of nuclear proteins with the NFκB binding site. The results support the view that DNA-binding drugs displaying high sequence-selectivity can exhibit distinct effects on the interaction between DNA and different DNA-binding proteins.

10

Geometrical assessment of the foetal lumbar vertebral column - clinical implications

63%

Czyz M., Kedzia A.

Folia Morphologica

|

2004

|

tom 63

|

nr 4

The neural arches, transverse processes, spinous processes, and superior and inferior articular processes of each of the 5 lumbar vertebrae can often be found under the common heading of ‘posterior element’. The aim of our study was to assess the changes in geometry of the posterior elements of the foetal lumbar vertebrae during the foetal period. A total of 50 human foetuses, both female and male, from natural abortions, C-R length ranging from 58 to 220 mm, were examined. The methodology of the research included classical anatomical preparation, detailed measurements of the structural elements of the lumbar vertebrae and statistical analysis. Geometrical reconstruction was subsequently performed. The shape of the posterior elements changed gradually from wide and massive to slender. We observed a descending sequence of these alterations, the first vertebra to change being L₁, with L₅ the last. The dynamic of the change was at its greatest during the first 4 weeks of the period evaluated. On the basis of our observations we concluded that the geometry of the posterior elements of the lumbar vertebrae undergoes a process of a great transformation during the foetal period, a process which progresses dynamically until the 14th week of intra-uterine development. The associations with micro-angiogenesis, the ossification process and the notion of structural adaptation of the lumbar spine to heightening mechanical stress are also discussed.

11

Targeting NF-kappaB and HIF-1 pathways for the treatment of cancer: Part I

51%

Wilczynski J., Duechler M., Czyz M.

Archivum Immunologiae et Therapiae Experimentalis

|

2011

|

tom 59

|

nr 4

12

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Can sexual behaviour serve to identify species? An example of two slugs of the genus Deroceras

51%

Czyz M., Reise H., Hutchinson J.

Folia Malacologica

|

2012

|

tom 20

|

nr 1

13

Using 3D scanning technology in malacological studies and education

51%

Kalinowski T., Czyz M., Jankowiak A., Bloszyk J.

Folia Malacologica

|

2012

|

tom 20

|

nr 1

14

Modulation of protein-DNA interactions by anthracycline derivatives

51%

Szulawska A., Gniazdowski M., Czyz M.

Acta Biochimica Polonica

|

2003

|

tom 50

|

nr Supplement 1

15

Using 3D scanning in allometric studies on Helix pomatia

51%

Czyz M., Kalinowski T., Goldyn B., Rybska E.

Folia Malacologica

|

2012

|

tom 20

|

nr 1

16

STI571 (imatinib) and doxorubicin induction of erythroid differentiation and apoptosis in CML cell line K562 is accompanied by Δψm dissipation

51%

Jakubowska J., Stasiak M., Bednarek A., Czyz M.

Acta Biochimica Polonica

|

2007

|

tom 54

|

nr Supplement 4

17

First records of Isohypsibius pushkini Tumanov, 2003 (Tardigrada, Eutardigrada, Hypsibiidae) from Poland

51%

Kaczmarek L., Goldyn B., Czyz M., Michalczyk L.

Biological Letters

|

2010

|

tom 47

|

nr 2

18

Terrestrial snails typical of forest ecosystems of Wielkopolska

51%

Jankowiak A., Kalinowski T., Czyz M.

Folia Malacologica

|

2012

|

tom 20

|

nr 1

19

Targeting NF-kappaB and HIF-1 pathways for the treatment of cancer: Part II

51%

Wilczynski J., Duechler M., Czyz M.

Archivum Immunologiae et Therapiae Experimentalis

|

2011

|

tom 59

|

nr 4

20

HBV core antigen (HBcAg) as a plant-based prototype of therapeutic hepatitis B vaccine and a carrier for HBV preS epitopes

51%

Pniewski T., Bogusiewicz M., Wyrwa K., Czyz M.

Acta Biologica Cracoviensia. Series Botanica. Supplement

|

2009

|

tom 51

|

nr 1

Ograniczanie wyników

Psoraleny jako narzędzia w badaniu struktury i funkcji kwasów nukleinowych

Specyficznosc i selektywnosc dzialania czynnika transkrypcyjnego NFkB

Ryzyko w sferze inwestycji proekologicznych

Metody analizy uwarunkowan ekologicznych wzrostu gospodarczego

Reaction of lime trees (Tilia sp.) growing along the Zwirki i Wigury Street in Warsaw on soil salinity caused by chemical technology of snow removal

New locality of vulnerable bivalve species Pisidium obtusale (Lamarck, 1819) (Sphaeriidae) with notes on its ecology and conservation status in Wielkopolska region (western Poland)

Preliminary metrological study of the lumbar vertebral column during the foetal period

Transcription factors as targets of anticancer drugs

Actinomycin D specifically inhibits the interaction between transcription factor Sp1 and its binding site

Geometrical assessment of the foetal lumbar vertebral column - clinical implications

Targeting NF-kappaB and HIF-1 pathways for the treatment of cancer: Part I

Can sexual behaviour serve to identify species? An example of two slugs of the genus Deroceras

Using 3D scanning technology in malacological studies and education

Modulation of protein-DNA interactions by anthracycline derivatives

Using 3D scanning in allometric studies on Helix pomatia

STI571 (imatinib) and doxorubicin induction of erythroid differentiation and apoptosis in CML cell line K562 is accompanied by Δψm dissipation

First records of Isohypsibius pushkini Tumanov, 2003 (Tardigrada, Eutardigrada, Hypsibiidae) from Poland

Terrestrial snails typical of forest ecosystems of Wielkopolska

Targeting NF-kappaB and HIF-1 pathways for the treatment of cancer: Part II

HBV core antigen (HBcAg) as a plant-based prototype of therapeutic hepatitis B vaccine and a carrier for HBV preS epitopes