Wyniki wyszukiwania

1

Release law of Sb, As, and Hg in antimony smelting slag under simulated acid rain

100%

Zhou S., Li N., Ren B., Zhang P.

Polish Journal of Environmental Studies

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2017

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tom 26

|

nr 2

This study takes the Southern antimony smelting slag depot in Xikuangshan (XKS) Sb mine in the city of Lengshuijiang, Hunan, China, as the research object and explores the release law of Sb, As, and Hg in smelting slag under different pH-value simulated acid rain by a semi-dynamic leaching experiment of simulating the local rain. The results show that the leachate pH value is positively correlated with the pH value of simulated acid rain, while the leachate conductivity is negatively correlated with it. The leaching rates of As and Hg are negatively correlated with the pH value of the simulated acid rain, while the leaching rate of Sb is positively correlated with it; in the leaching process, the leachate pH value goes downward slowly after shooting up, but the leachate conductivity is continuously reduced; the releasing process of Sb, As, and Hg consists of two stages, and their leaching rate forms such an order as Sb > Hg > As. The diffraction peak intensity of the main mineral composition of quartz and calcite decreases significantly after leaching; the smelting slag’s surface becomes less rough than before leaching, with fewer pores and edges, and the contents of S, Si, Al, Fe, Ca, and Sb on the slag surface decrease while the content of O, As, and Hg increases.

2

Evaluation of mathematical models in nitrogen transfer to overland flow subjected to simulated rainfall

100%

Xie M., Zhang Z., Zhang P.

Polish Journal of Environmental Studies

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2020

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tom 29

|

nr 2

3

Long non-coding RNA LINC00662 promotes proliferation and migration of breast cancer cells via regulating the miR-497-5p/EglN2 axis

100%

Cheng L., Xing Z., Zhang P., Xu W.

Acta Biochimica Polonica

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2020

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tom 67

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nr 2

4

Influence of surface texture parameters on friction characteristics under starved lubrication

100%

Wu S., Zhang P., Wei H., Chen L.

Polish Maritime Research

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2020

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tom 27

|

nr 2

5

Ecological service evaluation: an empirical study on the Central Loess Plateau, China

100%

Li Y., Zhang P., Qin Y.

Polish Journal of Environmental Studies

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2020

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tom 29

|

nr 2

6

MiR-378a-5p regulates CAMKK2/AMPK pathway to contribute to cerebral ischemia/reperfusion injury-induced neuronal apoptosis

100%

Zhang Y., Zhang P., Deng C.

Folia Histochemica et Cytobiologica

|

2021

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tom 59

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nr 1

7

Soil water and salt transport and its influence on groundwater quality: a case study in the Kongque River Region of China

88%

Dong W., Wen C., Zhang P., Su X., Yang F.

Polish Journal of Environmental Studies

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2019

|

tom 28

|

nr 3

Unreasonable exploitation of groundwater resources in the Kongque River region has led to a decline in the groundwater table, groundwater salinization, and other geo-environmental problems. Therefore, this study supplements the studies on soil water and salt transport in the Kongque River region, and provides a new method for the prevention of groundwater salinization in arid and semiarid regions. In this study, soil column experiments were carried out to investigate the influence of lithological structures of the unsaturated zone, water quality, and methods of irrigation on soil water and salt transport. Based on the data from the experiment, a one-dimensional model of soil water and salt transport was built to predict the impact of long-term irrigation on groundwater quality using Hydrus-1D. The results showed that groundwater TDS increased in the predicted scenarios and that groundwater quality was greatly influenced by irrigation water with high TDS values. The influence of long-term irrigation on groundwater quality was smallest for drip irrigation, which can save water and should be promoted. The influence of irrigation on groundwater quality was largest for flood irrigation. If flood irrigation cannot be avoided, then it is recommended that water with a TDS below 2 g/L should be used.

8

In vitro antioxidant activity of Artemisia argyi powder and the effect on hepatic and intestinal antioxidant indices in broiler chickens

76%

Zhang P., Chen H., Shi B., Zhao F., Guo X., Jin X., Yan S.

Annals of Animal Science

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2020

|

tom 20

|

nr 3

9

Physiological adaptations of Elymus dahuricus to high altitude on the Qinghai-Tibetan Plateau

76%

Cui G., Ji G., Liu S., Li B., Lian L., He W., Zhang P.

Acta Physiologiae Plantarum

|

2019

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tom 41

|

nr 07

The harsh natural environment on the Qinghai–Tibetan Plateau has a detrimental effect on the growth of vegetation. Elymus dahuricus, a widely distributed perennial herb on the Qinghai–Tibetan Plateau, is highly adapted to alpine regions. To unveil the mechanism of E. dahuricus adaptation to high altitude on the Qinghai–Tibetan Plateau, the relative photosynthetic characteristics and physiological indexes of wild E. dahuricus collected from different elevations in Huangzhong County and Minhe County of Qinghai Province were investigated. Increases in the maximum photochemical efficiency (Fv/Fm), potential activity (Fv/Fo), non-photochemical quenching (NPQ), total carotenoids content (Car), chlorophyll a to chlorophyll b ratio (Chl a/b) and total carotenoids to chlorophyll ratio (Car/Chl) were accompanied by decreases in photochemical quenching coefficient (qP), effective photochemical quantum yield of PSII (Y(II)) and chlorophyll a (Chl a) and chlorophyll b (Chl b) contents. Increases in Fv/Fm and Fv/F0 with altitude indicate that the photosynthetic capacity can be maintained with increases in altitude. As a photoprotective mechanism, decreases in chlorophyll content could lead to a reduction in the absorption of high energy light by leaves; therefore, the photosynthetic capacity of E. dahuricus was maintained on the Qinghai–Tibetan Plateau. Furthermore, the increasing malondialdehyde content along altitudinal gradients indicated that the alpine environments had an adverse effect on E. dahuricus growth. The increase in superoxide dismutase, peroxidase and catalase activities reflected a higher reactive oxygen species scavenging capacity, and the increases in soluble sugar and proline contents increased the osmotic adjustment substance contents, suggesting that the reactive oxygen species scavenging ability and osmotic pressure regulation play roles in maintaining the normal growth of E. dahuricus. In conclusion, the high altitude on the Qinghai–Tibetan Plateau negatively affected E. dahuricus growth, and the adaptation mechanism and survival strategies of E. dahuricus were ascribed to the comprehensive effects of photosynthetic capacity, reactive oxygen species scavenging and osmotic adjustments.

10

Gene expression profiles of various cytokines in mesenchymal stem cells derived from umbilical cord tissue and bone marrow following infection with human cytomegalovirus

76%

Li Q., Yu P., Wang W., Zhang P., Yang H., Li S., Zhang L.

Cellular and Molecular Biology Letters

|

2014

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tom 19

|

nr 1

Mesenchymal stem cells (MSCs) have both multi-lineage differentiation potential and immunosuppressive properties, making them ideal candidates for regenerative medicine. However, their immunosuppressive properties potentially increase the risk of cancer progression and opportunistic infections. In this study, MSCs isolated from human umbilical cord blood (UCMSCs) and adult bone marrow (BMMSCs) were infected with human cytomegalovirus (HCMV). Cytopathic changes were observed 10 days post infection. PCR products amplified from genomic DNA and cDNA were used to confirm the HCMV infection of the UCMSCs and BMMSCs. Real-time PCR was conducted to quantify the expression of immunomodulatory molecules, including cytokines, chemokines, growth factors, adhesion molecules and cancer-related genes. Our results indicate high upregulation of the majority of these molecules, including many growth factors, tumor necrosis factor alpha, interleukin-8, interleukin-6 and interferon gamma. Adhesion molecules (VCAM-1, TCAM-1 and selectin-E) were downregulated in the infected UCMSCs and BMMSCs. Antibody chip array evaluation of cell culture media indicated that the growth factor secretion by UCMSCs and BMMSCs was greatly influenced (p < 0.001) by HCMV. The stimulation of MSCs with HCMV led to the activation of downstream signaling pathways, including pSTAT3 and Wnt2. Our results show that HCMV can significantly alter the functions of both UCMSCs and BMMSCs, although not in the same way or to the same extent. In both cases, there was an increase in the expression of proangiogenic factors in the microenvironment following HMCV infection. The discrepancy between the two cell types may be explained by their different developmental origin, although further analysis is necessary. Future studies should decipher the underlying mechanism by which HCMV controls MSCs, which may lead to the development of new therapeutic treatments.

11

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Expression analysis of multifunctional RNA-binding protein hnRNP K during development of mammalian testis

76%

Xu H., Zhang P., Li R., Wu W., Wang S., Xu Y.

Polish Journal of Veterinary Sciences

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2018

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tom 21

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nr 2

12

tification of microRNAs from Zn-treated Solanum nigrum roots by small RNA sequencing

76%

Xie Z., Zhang P., Zhao J., Wang R., Gao J., Xu J.

Acta Physiologiae Plantarum

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2017

|

tom 39

|

nr 01

13

Exogenous melatonin reduced blood pressure in late-term ovine fetus via MT1/MT2 receptor pathways

76%

Tao J., Lv J., Li W., Zhang P., Mao C., Xu Z.

Reproductive Biology

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2016

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tom 16

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nr 3

14

Molecular cloning and analysis of the human PCAN1 [GDEP] promoter

64%

Liu W., Chen W., Zhang P., Yu C., Kong F., Deng J., Zhang J., Jiang A.

Cellular and Molecular Biology Letters

|

2007

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tom 12

|

nr 4

482-492

Human PCAN1 (prostate cancer gene 1) is a prostate-specific gene that is highly expressed in prostate epithelial tissue, and frequently mutated in prostate tumors. To better understand the regulation of the PCAN1 gene, a 2.6-kb fragment of its 5′ flanking region was obtained by PCR. Its promoter activity was examined via the dual-luciferase reporter assay after it had been cloned into a pGL3-basic vector generating pGL3-p2.6kb and transfected into LNCaP cells. pGL3-basic and pGL3-control were respectively used as the negative and positive controls. Sequence analysis with the MatInspector database showed that some possible binding sites for the transcriptional factors, NKX3.1, P53, SP1, cEBP and the PPAR/RXR heterodimers may locate on a 2.6-kb region upstream of the PCAN1 gene. To examine the relevant regulation of PCAN1, pGL3-p2.6kb was transfected into the prostate cancer cell line LNCaP, which was treated with R1881 (10−7∼10−9 mol/l), 17β-estradiol (17β-E2, 10−7∼10−9 mol/l), all-trans-retinoic acid (all-trans-RA, 10−5∼10−7 mol/l) or 9-cis-retinoic acid (9-cis-RA, 10−5∼10−7 mol/l), and eukaryotic expression plasmids of NKX3.1, p53, Sp1, Pten, PPARγ or cEBPα were cotransfected with pGL3-p2.6kb into LNCaP cells. pRL-TK, a Renilla luciferase reporter vector, was cotransfected into all the transfection lines as an internal control. The activities of pGL3-p2.6kb (PCAN1 promoter) were analyzed via the dual-luciferase reporter assay 48 h after transfection. The results showed that 9-cis-RA enhanced the PCAN1 promoter activity in a dose-dependent manner, while R1881, 17β-E2 and all-trans-RA had no significant effect on PCAN1 promoter activities. Cotransfection with pGL3-p2.6kb and the expression plasmids of NKX3.1, p53, Sp1 or Pten respectively resulted in 1.66-, 2.48-, 2.00-and 1.72-fold 2.6 kb PCAN1 promoter activity increases relative to the controls, which were cotransfected with pcDNA3.1(+), while cotransfection of PPARγ and cEBPα yielded no significant effect on PCAN1 promoter activities. These results could be applied for further study of the function and transcription regulation of the PCAN1 gene in prostate development and carcinogenesis.

15

Chinese cabbage BrMYB34.2 transcription factor regulates indolic glucosinolates biosynthesis in Arabidopsis

64%

Zhao Y., Zhang Y., Guo X., Ma Y., Zhang P., Liu H., Liu G., Guo J.

Acta Scientiarum Polonorum. Hortorum Cultus

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2020

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tom 19

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nr 1

Glucosinolates (GS) are a group of sulfur- and nitrogen-rich plant secondary metabolites that originate from amino acids and exist mainly in plants in the order Brassicales, such as Arabidopsis thaliana (Arabidopsis) and Chinese cabbage (Brassica rapa ssp. pekinensis). To date, several regulatory components responsible for GS biosynthesis have been identified in Arabidopsis. However, the functions of GS biosynthesis regulators in Chinese cabbage have not been clarified. In our current study, a putative ATR1/MYB34 orthologous gene, BrMYB34.2, was isolated from Chinese cabbage leaves. To investigate the function of this gene, we engineered Arabidopsis plants that overexpress BrMYB34.2 ectopically and phenotypic analysis was performed. Moreover, we assayed the accumulation levels of indolic GS (IGS) and aliphatic glucosinolates in transgenic plants and test the expression of key genes of IGS biosynthesis and tryptophan synthesis by Real-time quantitative PCR. And further analysed the resistance of transgenic plants in 5MT stress treatment. The results indicate that ectopic expression of the BrMYB34.2 gene in Arabidopsis was able to up-regulate the accumulation level of IGS due to the increased expression of IGS and Trp biosynthetic genes. Moreover, overexpression of BrMYB34.2 conferred Arabidopsis 5MT resistance. These results suggest that the BrMYB34.2 gene may function as one of the regulators of IGS and Trp biosynthesis in Chinese cabbage.

16

RNA interference against Biot2, a novel mouse testis - specific gene, inhibits the growth of tumor cells

64%

Wang C. T., Zhang P., Wang Y.-S., Ruan X.-Z., Li Z.-Y., Peng F., Yang H.-S., Wei Y.-Q.

Cellular and Molecular Biology Letters

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2009

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tom 14

|

nr 3

363-376

Biot2 is a novel murine testis-specific gene that was first identified using the SEREX technique, and named by our laboratory. Using conventional RT-PCR and real time RT-PCR, we tested the expression profile of Biot2 in normal tissues and various murine tumor cell lines. Using RNA interference, we studied the biological function of Biot2 in tumorigenesis. We applied various types of growth assay, such as the in vitro MTT, colony-forming and BrdU incorporation assays, along with in vivo tumorigenicity assays, to reveal its inhibition of tumor cell proliferation. The results revealed that the Biot2 transcript was detected only and strongly in the testis tissues and abundantly in five types of murine cancer cell line. Treating B16 murine melanoma, LL/2 murine Lewis lung carcinoma and CT26 murine colorectal adenocarcinoma with special shRNA targeting Biot2 can significantly reduce the proliferation rate of these three tumor cell lines in vitro, as measured by the MTT, colony-forming and BrdU incorporation assays. The tumorigenicity of the CT26 cells transfected with special shRNA targeting Biot2 was also decreased distinctly in vivo compared with the control. It was therefore concluded that Biot2 plays a key role in tumorigenesis and could be a potential target for biotherapy.

17

Effect of Val66Met polymorphism in BDNF on attentional bias in an extroverted Chinese Han population

64%

Gong P., Xi S., Li S., Cao G., Zhang P., Shen G., Zhang F., Shen Y., Ma H.

Acta Neurobiologiae Experimentalis

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2013

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tom 73

|

nr 2

Studies have indicated that a functional polymorphism (Val66Met) in a brain-derived neurotrophic factor (BDNF) gene can influences human cognitive functions and mood disorders. In this study, we examined associations of BDNF Val66Met with attentional bias and personality in an unaffected population. The results showed that BDNF Val66Met was significantly associated with attentional disengagement for positive cueing words in extraverts. Moreover, there was a positive correlation between the dosages of Met allele and attentional disengagement, however, we did not observe any significant influences of BDNF Val66Met on personality traits. These preliminary results indicate that the individual differences in attentional bias for positive words are partially underpinned by BDNF.

18

Comparison of the ossification centre images between standard computed tomography and micro-computed tomography

64%

Wang W., Wang X., Ren X., Chen L., Li Z., Li X., Zhang P., Gao J., Su B., Zhang S.

Folia Morphologica

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2020

|

tom 79

|

nr 1

Background: Based on standard computed tomography (CT) and micro-CT scan axis images, our study aims to analyse the incidence of variation of non-fusion ossification centre in the base of the odontoid and its anatomical structure characteristics, to compare ossification centre images and analyse the possible features of the ossification centre that can influence adult odontoid fractures. Materials and methods: Fifty cases were selected for standard cervical CT of the normal axis bone (second cervical) anatomy to calculate the incidence of variation of the non-fusion ossification centre in the base of the odontoid and the indexes of associated anatomical structure. In addition, five dry bone samples with the odontoid were chosen for micro-CT to analyse the clear anatomic structure of the trabecular bone in the ossification centre. Results: Incidence of variation of non-fusion ossification centre in the base of the odontoid was 28%. In the non-ossification group, the mean sagittal diameter of the base of odontoid (SDBO, mm) was 7.64 ± 1.29 mm, the mean transverse diameter of the base of odontoid (TDBO, mm) was 7.14 ± 1.55 mm, and the SDBO:TDBO ratio was 1.1 ± 0.22. In the ossification group, the mean SDBO was 7.7 ± 1.15 mm, the mean TDBO was 7.38 ± 1.32 mm, and the SDBO:TDBO ratio was 1.07 ± 0.21. There was no significant difference in the associated indexes between the ossification and non-ossification groups (p > 0.05). Micro-CT revealed the micro-structure of trabecular bone in the ossification centre and the close relationship between the trabecular bone and the odontoid. One existing non-ossification centre in the base of the odontoid was found in the five odontoid images. The trabecular bone indexes chosen in the target area of the ossification centre were weaker than those in other areas. Conclusions: The variation rate of the non-fusion ossification centre in the base of the odontoid is relatively high and may be an important factor in the aetiology of type II and III odontoid fractures. (Folia Morphol 2020; 79, 1: 141–147)

19

An integrative bioinformatics analysis identified miR-375 as a candidate key regulator of malignant breast cancer

52%

Liu J., Wang P., Zhang P., Du H., Liu X., Huang B., Qian C., Zhang S., Zhu W., Yang X., Xiao Y., Liu Z., Luo D.

Journal of Applied Genetics

|

2019

|

tom 60

|

nr 3-4

Ograniczanie wyników

Release law of Sb, As, and Hg in antimony smelting slag under simulated acid rain

Evaluation of mathematical models in nitrogen transfer to overland flow subjected to simulated rainfall

Long non-coding RNA LINC00662 promotes proliferation and migration of breast cancer cells via regulating the miR-497-5p/EglN2 axis

Influence of surface texture parameters on friction characteristics under starved lubrication

Ecological service evaluation: an empirical study on the Central Loess Plateau, China

MiR-378a-5p regulates CAMKK2/AMPK pathway to contribute to cerebral ischemia/reperfusion injury-induced neuronal apoptosis

Soil water and salt transport and its influence on groundwater quality: a case study in the Kongque River Region of China

In vitro antioxidant activity of Artemisia argyi powder and the effect on hepatic and intestinal antioxidant indices in broiler chickens

Physiological adaptations of Elymus dahuricus to high altitude on the Qinghai-Tibetan Plateau

Gene expression profiles of various cytokines in mesenchymal stem cells derived from umbilical cord tissue and bone marrow following infection with human cytomegalovirus

Expression analysis of multifunctional RNA-binding protein hnRNP K during development of mammalian testis

tification of microRNAs from Zn-treated Solanum nigrum roots by small RNA sequencing

Exogenous melatonin reduced blood pressure in late-term ovine fetus via MT1/MT2 receptor pathways

Molecular cloning and analysis of the human PCAN1 [GDEP] promoter

Chinese cabbage BrMYB34.2 transcription factor regulates indolic glucosinolates biosynthesis in Arabidopsis

RNA interference against Biot2, a novel mouse testis - specific gene, inhibits the growth of tumor cells

Effect of Val66Met polymorphism in BDNF on attentional bias in an extroverted Chinese Han population

Comparison of the ossification centre images between standard computed tomography and micro-computed tomography

An integrative bioinformatics analysis identified miR-375 as a candidate key regulator of malignant breast cancer