Wyniki wyszukiwania

1

Dziedzictwo kulturowe – dobro czy produkt rynkowy

100%

Madej J.

Wieś i Doradztwo. Pismo Małopolskiego Stowarzyszenia Doradztwa Rolniczego

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2012

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nr 3-4

2

Wplyw podawania paszy zainfekowanej grzybami z rodzaju Drechslera i Bipolaris na organizm myszy

63%

Madej J., Krzywiecki S.

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

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1995

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tom 193

189-198

3

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Larwy tetrathyridium tasiemca Mesocestoides lineatus u psa

51%

Dzimira S., Madej J., Soltysiak Z., Lewicka M.

Wiadomości Parazytologiczne. Suplement

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2007

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tom 53

53

4

Właściwości nasienia królików przed i po wyłączeniu wydzieliny gruczołu pęcherzykowego

51%

Dubiel A., Krolinski J., Karpiak C., Madej J.

Medycyna Weterynaryjna

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1985

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tom 41

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nr 07

Исследования имели целью показание свойств семени кроликов-самцов по исключении секрета пузырьковидной железы путем уничтожения его секреторного эпителия при помощи AgNO₃. Для набюдения использовали эякуляты 21 кролика. Животных разделили на 3 группы. Самцы I (8 голов) и II (7 голов) ввели в пузырьковидные железы —О (I группа) и 4% AgNO₃ (II группа) в количестве 1—2 мл. Остальных 6 животных являлось контрольной группой. Отметили, что пузырьковидная железа кролика решает о продукции слизисто-желеобразной фракции семени. Возможно также участие ее секрета в продукции жидкой фракции эякулята. Характерной чертой эякулятов кроликов является очень высокая активность GGTP и щелочной фосфатазы, зато значительно меньшая активность AspAT.

5

Komputerowe przetwarzanie danych patomorfologicznych na przykladzie chloniakow zlosliwych u psow

51%

Madej J. A., Nowak M., Dzimira S., Madej J.

Medycyna Weterynaryjna

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2002

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tom 58

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nr 10

770-773

6

The growth and flowering of Salvia splendens Sellow ex Roem. et Schult. under flowerbed conditions

51%

Blazewicz-Wozniak M., Madej J., Rtemi D., Wartacz W.

Acta Agrobotanica

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2012

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tom 65

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nr 2

The aim of the study was to determine the influence of accompanying plants as well as bark mulching, common for green areas, on the growth, flowering and decorative values of scarlet sage Salvia splendens Sellow ex Roem. et Schult. The field experiment included two cultivars of sage: ‘Red Torreador’ and ‘Luna’; two species of accompanying plants: French marigold – Tagetes patula nana L. ‘Petit Gold’ and flossflower – Ageratum houstonianum Mill.; as well as pine bark mulching. The control group was a monoculture of scarlet sage, without mulching. Pine bark mulching had a beneficial influence on almost all growth and flowering characteristics of scarlet sage. The plants growing on mulched soil were higher, had more leaves and branches as well as their inflorescences were longer and had more whorls than the plants growing without mulching. S. splendens growing with other species had fewer leaves and fewer branches. Its side stems and lateral inflorescences were shorter. The accompanying species also limited the mass of scarlet sage. The vicinity of marigold and flossflower had no influence on the height of S. splendens plants, the number of whorls and flowers within inflorescences. The growth of scarlet sage was largely modified by weather conditions; the plants grew best between June 20th and July 18th, with the best decorative effect achieved in July. The drought caused the flowers to dry out during the second half of the summer each year, limiting the decorative values of sage.

7

The effect of Lydium-KLP preparation on the course of infection of mouse with influenza virus

51%

Madej J., Klimentowski S., Kuryszko J., Rypula K.

Zeszyty Naukowe Akademii Rolniczej we Wrocławiu. Weterynaria

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1996

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tom 55

59-66

8

Wplyw splenoktomii na przebieg odpowiedzi humoralnej i komorkowej oraz morfologie centralnych narzadow limfatycznych u kurczat immunizowanych roznymi antygenami

51%

Graczyk S., Madej J., Pliszczak-Krol A.

Zeszyty Naukowe Akademii Rolniczej we Wrocławiu. Weterynaria

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1998

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tom 58

7-15

9

Ceramide galactosyltransferase (UGT8) as a molecular marker of canine mammary tumor malignancy

51%

Nowak M., Dziegiel P., Madej J., Ugorski M.

Folia Histochemica et Cytobiologica

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2013

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tom 51

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nr 2

10

Endothelial secretogogues and deformability of erythrocytes

51%

Korbut R. A., Adamek-Guzik T., Madej J., Korbut R.

Journal of Physiology and Pharmacology

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2002

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tom 53

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nr 4,1

Many diseases of the heart and circulatory system have been linked with both dysfunction of vascular endothelium and insufficient deformability of erythrocytes. Using shear stress laser diffractometry we investigated whether deformability of erythrocytes would be regulated endogenously by generation of two endothelial secretogogues: prostacyclin and nitric oxide. Experiments were performed in rats ex vivo and with whole blood or isolated erythrocytes in vitro. Iloprost - a stable analogue of prostacyclin (10 µg/kg i.v.) and SIN-1 (NO-donor) at a dose of 2 mg/kg/min i.v induced a significant improvement of deformability of erythrocytes ex vivo. Improvements of deformability by these two compounds were also evident in vitro when they were applied at a range of concentrations of 1 µM and 3 µM, respectively. Cyclooxygenase (indomethacin 20 mg.kg i.v.) and nitric oxide synthase (L-NAME 10 mg/kg i.v.) inhibitors while worsening deformability ex vivo, they did not affect (3 mM and 10 µM, respectively) rheological functions of erythocytes in vitro. Aggravating effects of these inhibitors on erythrocyte deformability ex vivo were reversed by prostacyclin and nitric oxide supplemented exogenously. Aspirin at a low (1 mg/kg i.v.) and high dose (50 mg/kg i.v.), contrary to indomethacin and L- NAME, aggravated erythrocyte deformability either ex vivo or in vitro. It is concluded that autocrine function of vascular endothelium plays an important role in regulation of rheology of red blood cells in flowing blood. The mechanism of this phenomenon is unclear but some possible explanations are discussed. In addition, in our experiments aspirin revealed unique erythrocyte damaging properties, possibly independent of inhibition of cyclooxygenase, but related to a direct protein acetylation.

11

Chromatographic analysis of phenolic acids present in vegetative and generative parts of Xanthium strumarium L.

51%

Zwolan W., Wolski T., Madej J., Najda A.

Herba Polonica

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2004

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tom 50

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nr 3-4

In this study the results of chromatographic analysis of phenolic acids isolated from vegetative and generative parts of X. strumarium L. are presented. The plants were collected in Pharmacognostic Garden, Lublin, Poland. Free phenolic acids and those released after acidic and basic hydrolysis were subjected to TLC and HPLC analyses. The following seven phenolics were identified: caffeic, gallic, protocatechuic, chlorogenic, vanillic, syringic and ferulic acids. The percentage content of phenolics is about 0.2393-0.2815% for herb, 0.2395-0.26627% for fruit, and 0.09138-0.09393% for root.

12

Secretory dysfunction of vascular endothelium limits the effect of angiotensin converting enzyme inhibitor quinapril on aggregation of erythrocytes in experimental hypertension

51%

Korbut R. A., Madej J., Adamek-Guzik T., Korbut R.

Journal of Physiology and Pharmacology

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2003

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tom 54

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nr 3

Using automatic erythrocyte aggregometer type MA-1 (Myrenne gmbh, Germany), we investigated the hypothesis that therapeutic effectiveness of quinapril - angiotensin converting enzyme inhibitor (ACEI) - in the treatment of hypertension would correlate with improvement of red blood cell (RBC) aggregability. Experiments were performed on commercially available inbred strain of spontaneously hypertensive male rats (SHR) aged 19-21 weeks. Age-matched normotensive Wistar-Kyoto (WKY) rats genetically related to SHR were used as a control. Aggregability of RBC in hypertensive rats was significantly higher than in control WKY animals. Quinapril (100 µg/kg) administered i.p. for 8 days improved RBC aggregability in normotensive rats but surprisingly not in SHR animals. Beneficial effect of quinapril on RBC aggregation observed in normotensive animals did not occur when this drug was injected in combination with aspirin (1 or 50 mg/kg) or with indomethacin (20 mg/kg) or with L-NAME (10 mg/kg). However, much the same damaging effects on RBC aggregability were observed when aspirin, indomethacin or L-NAME were each administered into normotensive animals without quinapril. In contrast with normotensive rats, aggregability of RBC in SHR was not affected either by quinapril or by indomethacin and by L-NAME, given separately or in combination. The only compound significantly worsening RBC aggregability in SHR was aspirin but this effect was not dose-dependent. Quinapril-induced improvement of RBC aggregability in normotensive rats (but not in SHR) was completely abolished by simultaneous administration of B2 receptor antagonist icatibant and successfully mimicked by 8 days of treatment with bradykinin. In vitro aggregability of RBC isolated from WKY was not affected by previous incubation (30 min at 37°C) with quinapril, indomethacin or L-NAME. Only aspirin (3 mM) significantly increased RBC aggregability as compared to placebo. It is concluded that under physiological conditions quinapril efficiently inhibits RBC aggregability and this effect is modulated by secretion of endothelial mediators, mainly prostacyclin and nitric oxide. In hypertension quinapril, in spite of lowering of arterial blood pressure, is unable to display its beneficial effects on RBC aggregability possibly due to the hypertension-induced/accompanied dysfunction of vascular endothelium. Aspirin revealed unique erythrocyte damaging properties, presumably independent of inhibition of cyclooxygenase but related to a direct membrane protein acetylation.

13

Doskonalenie składu niskobiałkowych mieszanek pełnoporcjowych dla kurcząt rzeźnych. Cz. I. Zmiana systemu żywienia kurcząt w pierwszych dniach życia

45%

Jamroz D., Schleicher A., Fritz Z., Sobiech K., Madej J.

Acta Agraria et Silvestria. Series Zootechnica

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1991

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tom 29

14

The effect of Lydium-KLP on the development of lymphatic leukaemia in AKR mice

45%

Madej J., Klimentowski S., Kuryszko J., Rypula K., Malinowski E.

Zeszyty Naukowe Akademii Rolniczej we Wrocławiu. Weterynaria

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1996

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tom 55

41-58

15

Inhibition of in vitro Histophilus somni biofilm production by recombinat Hsp60 antibodies

45%

Zarankiewicz T., Madej J., Galli J., Bajzert J., Stefaniak T.

Polish Journal of Veterinary Sciences

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2012

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tom 15

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nr 2

Histophilus somni is an opportunistic pathogen causing respiratory, genitourinary and generalized infections in cattle. An important virulence factor is its ability to produce a biofilm. The aim of this work was to confirm that H. somni Hsp60 (Gro-EL) is a constituent of the biofilm produced by this bacterium in vitro and to check whether or not the presence of a specific antibody within the culture medium can inhibit biofilm production. Biofilm production by H. somni cultured in vitro was confirmed by crystalline violet staining. The presence of Hsp60 in the biofilm was confirmed by using specific antibodies produced in a mouse and goat hyperimmunized with H. somni recombinant Hsp60 (rHsp60). Large complexes of biofilm stained with Hsp60 antibodies were microscopically detected. This indicates that the Hsp60 protein is a common constituent of the biofilm produced by H. somni in vitro. In a second experiment, mouse serum containing anti- H. somni rHsp60 antibodies was added to an H. somni culture. It was found that the presence of anti-rHsp60 antibodies in the culture medium inhibited biofilm production in vitro. Only small biofilm particles were seen in the presence of the specific antibody, whereas in control cultures (without specific antiserum) large biofilm complexes were produced. The results indicate that antibodies specific to Hsp60 may be useful for preventing H. somni biofilm formation in vitro. If this also occurs in vivo, it may be helpful for eradicating H. somni infection in cattle through the elimination of carriers. Further in vivo studies are needed to confirm this idea.

16

Quantification of airborne birch [Betula sp.] pollen grains and allergens in Krakow

45%

Madej J., Wypasek E., Plytycz B., Sarapata K., Harmata K.

Archivum Immunologiae et Therapiae Experimentalis

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2005

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tom 53

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nr 2

17

Activity of glycogen depolymerizing enzymes in extracts from brain tumor tissue [anaplastic astrocytoma and glioblastoma multiforme]

45%

Kotonski B., Wilczek J., Madej J., Zarzycki A., Hutny J.

Acta Biochimica Polonica

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2001

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tom 48

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nr 4

An approximately threefold increase in glycogenolytic activity of the neutral a-1,4-glucosidase and a twofold increase in the same activity of the acid isoform have been found in extracts of anaplastic astrocytoma and glioblastoma multiforme tumors of brain tissue. "Maltase activity" of the respective enzymes increased by 60-80% in both kinds of tumor extracts. However a significant decrease in a-amylase and almost complete disappearance of phosphorylase activities have also been found in both kinds of tumors.

18

Angiotensin metabolism in rat stomach wall: prevalence of angiotensin-(1-7) formation

39%

Olszanecki R., Madej J., Suski M., Gebska A., Bujak-Gizycka B., Korbut R.

Journal of Physiology and Pharmacology

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2009

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tom 60

|

nr 1

191-196

Our view of renin-angiotensin system (RAS) has changed over the past two decades: new metabolites and pathways have been described; also the importance of local renin-angiotensin systems became more clearly understood. However, there is relatively scarce information about formation and action of angiotensin peptides in gastrointestinal tract, especially in the stomach. Here, using LC-ESI-MS method we assessed the metabolism of Ang I in organ bath of rat stomach wall. Additionally we compared the expression of mRNA of angiotensin converting enzymes (ACE, ACE2) and neprilysin (NEP) in the stomach, aorta and renal artery in rats. Despite, similar levels of expression of ACE and ACE2 mRNA in stomach wall, aorta and renal artery, the absolute amounts of main Ang I metabolites produced by stomach wall (in ng/mg of dry tissue) were much lower than that produced by aorta and renal artery. Also, the pattern of angiotensin I metabolites was different: opposite to aorta and renal artery, incubation of Ang I with stomach wall fragments resulted in predominant formation of Ang-(1-7) and relatively lower production of Ang II. In stomach wall both, perindoprilat and tiorphan decreased production of Ang II, but did not influence generation of Ang-(1-7). In conclusion, we identified Ang-(1-7) as the main product of Ang I conversion in rat stomach wall. The biological role of prevalence of Ang-(1-7) formation in stomach require further investigation.

19

Metabolism of bradykinin in aorta of hypertensive rats

39%

Bujak-Gizycka B., Olszanecki R., Madej J., Suski M., Gebska A., Korbut R.

Acta Biochimica Polonica

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2011

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tom 58

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nr 2

Alterations in the formation and metabolism of bradykinin (Bk) are hypothesized to play a role in the pathophysiology of hypertension, atherosclerosis and vascular complications of diabetes. However, despite its prominent role in cardiovascular regulation, studies on bradykinin have been limited by various difficulties in accurate measurements of this peptide in biological samples. In this study, using the LC-ESI-MS method we estimated the conversion of exogenous Bk to its main metabolites - Bk-(1-5) and Bk-(1-7) - in endothelial cell culture and in fragments of aorta of normotensive (WKY) and hypertensive rats (SHR). The effects of angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) inhibitors were more pronounced in SHR: perindoprilat inhibited Bk-(1-5) formation by 49 % and 76 % in WKY and SHR rats, respectively, and tiorphan tended to decrease formation of Bk-(1-5) in both groups of animals. The degradation of bradykinin and generation of both metabolites were significantly higher in the aorta of SHR rats than in WKY controls. Our results show that even in relatively early hypertension (in 4-month old SHR rats) inactivation of Bk by aorta wall is enhanced.

20

Angiotensinogen metabolism in rat aorta: Robust formation of proangiotensin-12

39%

Bujak-Gizycka B., Olszanecki R., Suski M., Madej J., Stachowicz A., Korbut R.

Journal of Physiology and Pharmacology

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2010

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tom 61

|

nr 6

Ograniczanie wyników

Dziedzictwo kulturowe – dobro czy produkt rynkowy

Wplyw podawania paszy zainfekowanej grzybami z rodzaju Drechslera i Bipolaris na organizm myszy

Larwy tetrathyridium tasiemca Mesocestoides lineatus u psa

Właściwości nasienia królików przed i po wyłączeniu wydzieliny gruczołu pęcherzykowego

Komputerowe przetwarzanie danych patomorfologicznych na przykladzie chloniakow zlosliwych u psow

The growth and flowering of Salvia splendens Sellow ex Roem. et Schult. under flowerbed conditions

The effect of Lydium-KLP preparation on the course of infection of mouse with influenza virus

Wplyw splenoktomii na przebieg odpowiedzi humoralnej i komorkowej oraz morfologie centralnych narzadow limfatycznych u kurczat immunizowanych roznymi antygenami

Ceramide galactosyltransferase (UGT8) as a molecular marker of canine mammary tumor malignancy

Endothelial secretogogues and deformability of erythrocytes

Chromatographic analysis of phenolic acids present in vegetative and generative parts of Xanthium strumarium L.

Secretory dysfunction of vascular endothelium limits the effect of angiotensin converting enzyme inhibitor quinapril on aggregation of erythrocytes in experimental hypertension

Doskonalenie składu niskobiałkowych mieszanek pełnoporcjowych dla kurcząt rzeźnych. Cz. I. Zmiana systemu żywienia kurcząt w pierwszych dniach życia

The effect of Lydium-KLP on the development of lymphatic leukaemia in AKR mice

Inhibition of in vitro Histophilus somni biofilm production by recombinat Hsp60 antibodies

Quantification of airborne birch [Betula sp.] pollen grains and allergens in Krakow

Activity of glycogen depolymerizing enzymes in extracts from brain tumor tissue [anaplastic astrocytoma and glioblastoma multiforme]

Angiotensin metabolism in rat stomach wall: prevalence of angiotensin-(1-7) formation

Metabolism of bradykinin in aorta of hypertensive rats

Angiotensinogen metabolism in rat aorta: Robust formation of proangiotensin-12