Wyniki wyszukiwania

1

Fannin-Lubbock-I [alpha2beta2119(GLY>ASP)], a rare mutation in the beta-globin gene, has been detected for the first time in a Hindu Brahmin family in West Bengal, India

100%

Basak J., Bhattacharyya D. M., Mukhopadhyay A.

Cellular and Molecular Biology Letters

|

2014

|

tom 19

|

nr 2

This study aims to describe the hemoglobin Fannin-Lubbock-I, which has a rare mutation substituting the amino acid glycine with aspartic acid at codon 119 of the β-globin chain. A Bengalee Hindu Brahmin family from Kolkata in West Bengal was the focus of this study. Molecular analysis using ARMS-PCR and direct DNA sequencing revealed the presence of a GGC > GAC mutation in codon 119 of the β-globin gene in a heterozygote state in three women of the same family. This is the first report of the hemoglobin Fannin-Lubbock-I from India. Our results will help to identify this mutation, which is relatively infrequent in our population.

2

The synergists action of piperonyl butoxide on toxicity of certain insecticides applied against Helopeltis theivora Waterhouse [Heteroptera: Miridae] in the Dooars tea plantations of North Bengal, India

100%

Roy S., Mukhopadhyay A., Gurusubramanian G.

Journal of Plant Protection Research

|

2009

|

tom 49

|

nr 2

225-228

Higher efficacy of mixture of insecticides with synergists piperonyl butoxide (PB) was reported in controlling in the Dooars population of Helopeltis theivora Waterhouse. Therefore, the use of synergists as one of the countermeasures against the insecticide resistance problem of H. theivora is recommended. The combination of deltamethrin +PB (piperonyl butoxide), quinalphos +PB and imidacloprid +PB showed 44.60, 16.01 and 11.14 folds increase of toxicity (synergistic ratio) than the respective insecticide alone. Piperonyl butoxide acted as an oxidase inhibitor. The addition of PB to some extent suppressed the resistance of H. theivora to these insecticides, suggesting that the P450 enzyme complex may be involved in the mechanism of toxicity.

3

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Dose- and time-dependent micronucleus induction in peripheral erythrocytes of catfish, Heteropneustes fossilis (Bloch) by zinc

100%

Talapatra S. N., Banerjee P., Mukhopadhyay A.

International Letters of Natural Sciences

|

2014

|

tom 04

As far as the detection of metal genotoxicity in fish is concerned, micronucleus (MN) test is considered an extremely suitable measure. In this study, frequencies of micronucleated erythrocytes were scored in peripheral blood of catfish, Heteropneustes fossilis (bloch) after acute in-vivo exposure of zinc at different concentrations (5, 10 and 30 ppm) in the laboratory condition. These three concentrations of zinc were tested at different durations such as 24h, 48h, 72h and 96h respectively. Highly significant (P < 0.001) increased values were obtained for MN frequencies in the peripheral erythrocytes of exposed fishes compared to control groups of fishes. These results confirm that dose- and time-dependent micronucleation in the peripheral erythrocytes of fish after short-term exposure to zinc could provide valuable information regarding zinc containing effluent quality and also help in genetic biomonitoring with this test model. In this context safe concentration of zinc vis-a-vis genotoxicity range could be evaluated for future studies.

4

Relative susceptibility of tea mosquito bug, Helopeltis theivora Waterhouse and red spider mite, Oligonychus coffeae Nietner eggs to commonly used pesticides

100%

Roy S., Mukhopadhyay A., Gurusubramanian G.

Journal of Plant Protection Research

|

2010

|

tom 50

|

nr 3

The tea mosquito bug (Helopeltis theivora Waterhouse) and red spider mite (Oligonychus coffeae Nietner) are the two major pests of tea (Camellia sinensis L.). Their intensity of infestation was increasing day by day in an alarming proportionand increasing resistance to pesticides constitutes a serious problem in North Bengal tea plantations, India. One of the insecticide resistance management strategies is the use of chemicals that can effectively control the pest in the initial life stage (egg stage). However most of the earlier studies were doneto control the mobile stages of H. theivora and O. coffeae. The present experiment was conducted to evaluate the effectiveness of acaricides/insecticides in killing its eggs. On the basis of LC50values, the descending order of ovicidal toxicity of different commonly used insecticides to H. theivora eggs were: etofenprox, β-cyfluthrin,cypermethrin, imidacloprid, fenpropathrin, λ-cyhalothrin, deltamethrin,profenofos, monocrotophos, thiomethoxam, alphamethrin, dimethoate, quinalphos,chlorpyriphos, oxydemeton methyl, acephate, azadirachtin and endosulfan. In case of O. coffeae eggs the lowest LC50 value was determined for fenazaquin, which was followed by profenophos, propargite, fenpropathrin,ethion, dicofol, abamectin and finally by azadirachtin. The data obtained in the present study may be used as a tool of IRM (integrated resistance management) strategies that can effectively control the pests in the initial stage itself (egg stage).

5

Studies on the effect of different insecticidal applications on quality, nutritional parameters and total antioxidant capacity of brinjal (Solanum melongena L.)

100%

Goswami M. R., Pati U. K., Maity P., Mukhopadhyay A.

International Letters of Natural Sciences

|

2018

|

tom 69

Brinjal (Solanum melongena L.) suffers from the attack of various pests throughout its different stages of the crop growth. Different insecticides are used to control these pest infestations. The application of these insecticides on brinjal plants may have an effect on their quality and nutritional parameters of fruit samples. In the present study effect of three different insecticides viz. Triazophos 40% E.C. Carbaryl 50% W.D.P, Cypermethrin 10% E.C. and Azadiractin 10,000 ppm formulation belonging to different groups namely organophosphate, carbamate, synthetic pyrethroids and botanical insecticide on brinjal fruit quality, nutritional parameters and total antioxidant capacity (TAC) were assessed in field conditions. The results showed that different insecticides at field application dose showed minute insignificant variation in fruit nutritional and total antioxidant activity parameters in comparison to the control samples. The fruit quality parameters also showed minute variation in comparison to the control, except in the case of Triazophos treated samples which showed significant variation (p<0.05) in total soluble sugar content and crude protein.

6

Detection of a novel mutation in exon 20 of the BRCA1 gene

88%

Chakraborty A., Katarkar A., Chaudchuri K., Mukhopadhyay A., Basak J.

Cellular and Molecular Biology Letters

|

2013

|

tom 18

|

nr 4

Hereditary breast cancer constitutes 5–10% of all breast cancer cases. Inherited mutations in the BRCA1 and BRCA2 tumor-suppressor genes account for the majority of hereditary breast cancer cases. The BRCA1 C-terminal region (BRCT) has a functional duplicated globular domain, which helps with DNA damage repair and cell cycle checkpoint protein control. More than 100 distinct BRCA1 missense variants with structural and functional effects have been documented within the BRCT domain. Interpreting the results of mutation screening of tumor-suppressor genes that can have high-risk susceptibility mutations is increasingly important in clinical practice. This study includes a novel mutation, p.His1746 Pro (c.5237A>C), which was found in BRCA1 exon 20 of a breast cancer patient. In silico analysis suggests that this mutation could alter the stability and orientation of the BRCT domain and the differential binding of the BACH1 substrate.

7

Survey of indoor air pollution and health symptoms at residential buildings

88%

Sarkar S., Nandy A., Talapatra S. N., Basu R., Mukhopadhyay A.

International Letters of Natural Sciences

|

2014

|

tom 08

|

nr 1

This survey work summarizes the generation of indoor air pollutants (IAPs) through household products and activities and also the probable health symptoms of IAPs were discussed through questionnaire in the residential buildings of urban and semi urban area when compared to rural (control) area by door to door survey. The IAPs are categorized as physical, chemical and biological and surveyed as per the product(s) usage in the closed room of buildings. The survey results of IAPs generated from household products and activities, these are asbestos, fine particulate matters and ash as physical pollutants. The chemical pollutants are carbon mono and di oxide gases, phthalates; DDT, chlordane, heptachlor, o-phenylphenol; PBDEs, Formaldehyde, Other Aldehydes, lead, benzene, chloroform, para-dichlorobenzene, methylene chloride, perchloroethylene, styrene, benzene, formaldehyde, terpenes, styrene, phthalate esters, toluene, Propellant, pesticides, PAH, NOx, acrylamide, VOCs, acetone, HCl gas and biological pollutants are bacteria, fungi, viruses, house dust mites, animal dander; cockroaches, microbial spore. In respect to established health impact data, the health symptoms were recorded after survey in two areas viz. urban and semi urban area. The health symptoms were recorded as eye, nose, and throat irritation; allergic reactions, respiratory irritation, aggravated asthma, influenza and other infectious diseases may be the generation of IAPs. The urban and semi urban area are compared with rural (control) area in which no symptoms were found as per discussion. In the present survey it was concluded that the generation of IAPs may from household products and activities in the urban and semi urban area due to less ventilation facilities when compared to rural (control) area. This is a preliminary observation, further researches are needed in relation to measurement of physical, chemical and biological indoor pollutants in closed room of residential buildings and also health hazards study of residents by haematological, biochemical, enzymological and genotoxicological parameters.

8

Assessment of morphological damages of leaves of selected plant species due to vehicular air pollution, Kolkata, India

88%

Nandy A., Talapatra S. N., Bhattacharjee P., Chaudhuri P., Mukhopadhyay A.

International Letters of Natural Sciences

|

2014

|

tom 04

The present study deals to know morphological damages of leaves of four selected plant species near roadside due to vehicular air pollution in Kolkata, India. The selected plant species are Ficus bengalensis, Ficus religiosa, Alstonia scholaris and Neolamarckia cadamba as these are very common as avenue trees. The study area was selected as per Low vehicular load (LVL) as control area, moderate vehicular load (MVL) area, high vehicular load (HVL) area and heavy vehicular load (HeVL) These three sampling stations were selected on the basis of moderate, high and heavy traffic density and continuous vehicular movement as per visualization. The control area was considered as time dependent vehicular movement due to less traffic density. The morphological damages with special reference to length (L), breadth (B) and L/B ratio and visible injuries in leaves. The visible injuries such as pigmentation, chlorosis, necrosis and burning of leaves of four selected species is documented. There was an increasing and decreasing tends in all four plant species at all three vehicular emission exposed sites (MVL, HVL and HeVL) compared to control site (LVL). In all experimental sites such as MVL, HVL and HeVL, the extra growth and reduction pattern significantly (P < 0.001, 0.01 or 0.05) observed when compared to control site (LVL) for L, B and L/B ratio. The visible injuries (in %) of leaves were also observed in increasing trends. This study is a preliminary assessment of tolerant species that already have been used in greenbelt development to protect air pollutants as well as biological monitoring to know exact load of automobile air pollution but further researches are needed in relation to biochemical and genetic damage study. It was observed that out of four selected species Ficus bengalensis, Alstonia scholaris and Neolamarckia cadamba are more tolerant species and Ficus religiosa is a less tolerant species because of these may have fighting abilities by waxy coatings, accumulation and degradation abilities to vehicular air pollution at all exposed area when compared to control area.

9

Assessment of biomarker with special reference to antioxidant level in blood as occupational exposure of sewage and garage workers

76%

Basu R., Talapatra S. N., Mukhopadhyay A., Ray S. S., Chakrabarti P., Chaudhuri U., Chakrabarti S.

International Letters of Natural Sciences

|

2014

|

tom 09

The present study deals with the estimation of antioxidant levels in blood of sewage and garage workers exposed to sewage water, washing water and vehicular air pollution compared with control group of population. The study areas were selected on the basis of drainage clearance and wards where workers are active as sewage workers. For garage workers, the garage selected was a large and busy one where continuous vehicles washing, repairing etc are carried out. These two exposed groups were compared to non-exposed group of population as control. The blood samples were collected from two groups of exposed population as well as control population and the antioxidant levels were estimated in blood. The present results clearly indicate that there was decreasing trend of the antioxidant level in blood for sewage and garage workers. In the control groups of population the antioxidant levels were found to be within normal range, but for sewage workers (0.14-0.36 mM) and garage workers (0.12-0.36 mM) the antioxidant levels were significantly lower. The range of antioxidant level in human blood is 0.5 to 2.0 mM. It was found to be significantly lower (P < 0.001 or 0.05) in addicted sewage and garage workers when compared with non-addicted groups. All the exposed groups were showed to be having significantly lower antioxidant level when compared to control groups. This study is a preliminary assessment to know the potent biomarkers for oxidative stress and estimation of antioxidant level in blood due to occupational exposure. This study shows a way for easy screening of biomarker assessment but further work is needed in relation to biochemical, enzymological and genetic damage study.

10

Dosage and temporal dependent arsenic-induced mortality in Ceriodaphnia dubia: An effective biomarker for arsenic pollution

76%

Talapatra S. N., Bhattacharya S., Guha G., Dutta S., Chattopadhyay D., Mukhopadhyay A.

International Letters of Natural Sciences

|

2014

|

tom 02

Arsenic (As) is a metalloid that causes severe water pollution due to its extravagant toxicity. Ceriodaphnia dubia, a freshwater crustacean, was selected as a model system to evaluate the degree of time and dosage dependent acute toxicity caused by pentavalent As [As(V)]. C. dubia were collected from a natural pond and treated with different concentrations of As(V) for 24 hours and 48 hours. For both 24 hours and 48 hours treatment periods, the mortality rates were increased significantly ( P< 0.05) with increase in As(V) concentrations. Simultaneously, it was also observed that As(V) - induced mortality in C. dubia also depended on the time of exposure to the metalloid. We propose this model as a low-cost technique towards rapid screening of water quality in relation to As contamination.

11

Trend of arsenic pollution and subsequent bioaccumulation in Oryza sativa and Corchorus capsularis in Bengal Delta

76%

Bhattacharya S., Guha G., Gupta K., Chattopadhyay D., Mukhopadhyay A., Ghosh U. C.

International Letters of Natural Sciences

|

2014

|

tom 16

Oryza sativa Linn. (rice) and Corchorus capsularis Linn. (jute) are the two major crops of the Bengal basin. Both rice and jute are generally grown in submerged flooded conditions, where arsenic bioavailability is high in soil. The consumers of the edible parts from both plants therefore face an inevitable source of exposure to arsenic, with consequent accumulation and toxicity. The objective of the study was to observe the in-vivo temporal variation of arsenic bioaccumulation in the different parts of O. sativa and C. capsularis. Rice plant specimens (Aman rice, Ratna variety) of different age groups (1, 2 and 3 months old) were analyzed in HG-AAS for absorbed arsenic content in different parts. The accumulation of arsenic remained significantly high in the initial phase of growth, but decreased with time. Amount of arsenic bioaccumulation followed the decreasing order: root > basal stem > median stem > apical stem > leaves > grains in all the three age groups of the rice plant samples. C. capsularis followed a trend of arsenic bioaccumulation similar to O. sativa. O. sativa had more accumulation potential than C. capsularis, but C. capsularis showed much higher efficiency of arsenic translocation in the above ground parts. This is the first ever report of time-dependent decrease in arsenic bioaccumulation in O. sativa and C. capsularis. The contamination level can reach the grain part in significant amount and can cause health hazards in more severely arsenic affected areas. Intensive investigation on a complete food chain is urgently needed in the arsenic contaminated zones for further risk assessments.

Ograniczanie wyników

Fannin-Lubbock-I [alpha2beta2119(GLY>ASP)], a rare mutation in the beta-globin gene, has been detected for the first time in a Hindu Brahmin family in West Bengal, India

The synergists action of piperonyl butoxide on toxicity of certain insecticides applied against Helopeltis theivora Waterhouse [Heteroptera: Miridae] in the Dooars tea plantations of North Bengal, India

Dose- and time-dependent micronucleus induction in peripheral erythrocytes of catfish, Heteropneustes fossilis (Bloch) by zinc

Relative susceptibility of tea mosquito bug, Helopeltis theivora Waterhouse and red spider mite, Oligonychus coffeae Nietner eggs to commonly used pesticides

Studies on the effect of different insecticidal applications on quality, nutritional parameters and total antioxidant capacity of brinjal (Solanum melongena L.)

Detection of a novel mutation in exon 20 of the BRCA1 gene

Survey of indoor air pollution and health symptoms at residential buildings

Assessment of morphological damages of leaves of selected plant species due to vehicular air pollution, Kolkata, India

Assessment of biomarker with special reference to antioxidant level in blood as occupational exposure of sewage and garage workers

Dosage and temporal dependent arsenic-induced mortality in Ceriodaphnia dubia: An effective biomarker for arsenic pollution

Trend of arsenic pollution and subsequent bioaccumulation in Oryza sativa and Corchorus capsularis in Bengal Delta