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1
Content available remote

Labeled [3H]-thymidine incorporation in the DNA of 3T3-L1 preadipocytes due to MT2- and not MT3- melatonin receptor

100%
Adamczyk-Sowa M., Sowa P., Zwirska-Korczala K., Pierzchala K.
Journal of Physiology and Pharmacology
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2014
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tom 65
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nr 1
2

A rare case of Bickerstaff’s brainstem encephalitis

100%
Slusarz K., Wierzbicki K., Adamczyk-Sowa M.
World Scientific News
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2019
|
tom 135
3
Content available remote

Antioxidative enzymes activity and malondialdehyde concentration during mitoxantrone therapy in multiple sclerosis patients

88%
Adamczyk-Sowa M., Sowa P., Pierzchala K., Polaniak R., Labuz-Roszak B.
Journal of Physiology and Pharmacology
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2012
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tom 63
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nr 6
4

Aktywność lizozymu w medium hodowlanym megakolonii komórek raka płaskonabłonkowego in vitro

88%
Polaniak R., Birkner E., Beck B., Duliban H., Adamczyk-Sowa M.
Diagnostyka Laboratoryjna
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2004
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tom 40
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nr 4
5

Influence of combined cisplatin and electromagnetic field treatment on antioxidative status in AT478 squamous cell carcinoma line-in vitro study

76%
Polaniak R., Bierkner E., Adamczyk-Sowa M., Zwirska-Korczala K., Monsiol A., Sowa P., Birkner K.
Acta Biochimica Polonica
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2006
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tom 53
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nr Supplement 1
6
Content available remote

Effect of melatonin supplementation on plasma lipid hydroperoxides, homocysteine concentration and chronic fatigue syndrome in multiple sclerosis patients treated with interferons-beta and mitoxantrone

76%
Adamczyk-Sowa M., Sowa P., Adamczyk J., Niedziela N., Misiolek H., Owczarek M., Zwirska-Korczala K.
Journal of Physiology and Pharmacology
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2016
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tom 67
|
nr 2
7
Content available remote

Influence of melatonin supplementation on serum antioxidative properties and impact of the quality of life in multiple sclerosis patients

76%
Adamczyk-Sowa M., Pierzchala K., Sowa P., Polaniak R., Kukla M., Hartel M.
Journal of Physiology and Pharmacology
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2014
|
tom 65
|
nr 4
8
Content available remote

The role of serotonergic 5-HT1A receptors in central cardiovascular regulation in hemorrhagic shock in rats

76%
Sowa P., Adamczyk-Sowa M., Zwirska-Korczala K., Namyslowski G., Misiolek M., Pierzchala K.
Journal of Physiology and Pharmacology
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2013
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tom 64
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nr 2
9
Content available remote

Proopiomelanocortin but not vasopressin or renin-angiotensin system induces resuscitative effects of central 5-HT1A activation in haemorrhagic shock in rats

76%
Sowa P., Adamczyk-Sowa M., Zwirska-Korczala K., Pierzchala K., Adamczyk D., Paluch Z., Misiolek M.
Journal of Physiology and Pharmacology
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2014
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tom 65
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nr 5
10
Content available remote

Effect of extremely low frequency electromagnetic fields on cell proliferation, antioxidative enzyme activities and lipid peroxidation in 3T3-L1 preadipocytes - an in vitro study

64%
Zwirska-Korczala K., Jochem J., Adamczyk-Sowa M., Sowa P., Polaniak R., Birkner E., Latocha M., Pilc K., Suchanek R.
Journal of Physiology and Pharmacology. Supplement
|
2005
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tom 56
|
nr 6
101-108
The exposure to extremely low frequency electromagnetic field (ELF-MF, frequencies less than 200-300 Hz) can alter the transcription and translation of genes, influence the cell proliferation rate and affect enzyme activities. Moreover, the hypothesis that ELF-MF increases free oxygen metabolites generation has been proposed. Since recent in vivo studies suggest that electric and magnetic fields are able to affect adipose cells metabolism. The aim of the study was to examine the effects of ELF-MF (frequency of basic impulse 180-195 Hz, induction 120 µT) on cell proliferation, antioxidative enzyme activities and malondialdehyde (MDA) concentration in 3T3-L1 preadipocyte cell culture. We found that ELF-MF application lasting 36 minutes daily failed to influence cell count after 24h and 48 h of incubation. After 24 h, in the ELF-MF treated group, manganese- and copper-zinc-containing superoxide dismutase (MnSOD and Cu/ZnSOD) isoenzymes media activities were decreased, catalase activity was increased, whereas there were no significant differences in glutathione peroxidase (GSH-Px) and glutathione reductase (GSSG-Rd) activities in comparison to the control. After 48 h of incubation, all enzyme activities were reduced, except for GSSG-Rd, in which no changes were noticed. MDA concentration at 24 h after incubation with the exposure to ELF-MF was significantly higher in comparison to the control, without ELF-MF. After 48 h of incubation, MDA levels were significantly lower in both groups with no differences between the groups without and with ELF-MF. We conclude that ELF-MF influences antioxidative enzyme activities and increases lipid peroxidation in 3T3-L1 preadipocyte cultures.
11
Content available remote

Influence of melatonin on cell proliferation, antioxidative enzyme activities and lipid peroxidation in 3T3-L1 preadipocytes - an in vitro study

64%
Zwirska-Korczala K., Jochem J., Adamczyk-Sowa M., Sowa P., Polaniak R., Birkner E., Latocha M., Pilc K., Suchanek R.
Journal of Physiology and Pharmacology. Supplement
|
2005
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tom 56
|
nr 6
91-99
Melatonin, acting via MT1, MT2 and MT3 membrane receptors, influences central and peripheral regulatory mechanisms of energy homeostasis in mammals. In peripheral tissues, it evokes the pro-proliferative effect in a number of normal cells. Moreover, this hormone inhibits lipolysis in subcutaneous adipocytes in vitro and reduces free oxygen metabolites-induced damage acting directly, as a free radical scavenger, and indirectly, by stimulation of antioxidative enzyme activities. The aim of the study was to examine the effects of melatonin on cell proliferation, antioxidative enzyme activities and malondialdehyde (MDA) concentration in 3T3-L1 preadipocyte cell culture. We found that melatonin (10-3 and 10-6 M/L) stimulated cell proliferation in dose- and time-depending manner, and this effect was inhibited by a relatively selective MT2 receptor antagonist - luzindole (10-4 M/L). Melatonin, increased activities of manganese containing and copper-zinc containing superoxide dismutase (MnSOD and Cu/ZnSOD) isoenzymes, catalase, glutathione reductase and glutathione peroxidase after 24 h of incubation. In contrast, after 48 h of incubation, activities of all studied enzymes were lower than in the control group. There were no changes in MDA concentrations after 24 h of incubation, whereas, in melatonin-treated media, after 48 h of the experiment, MDA level was significantly decreased. Our results demonstrate that melatonin, acting via MT2 receptors, stimulates proliferation of 3T3-L1 preadipocytes and this action could be due to the enhancement in antioxidative enzyme activities and attenuation of lipid peroxidation by this indole.
12
Content available remote

Basal and postprandial plasma levels of PYY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome

52%
Zwirska-Korczala K., Konturek S. J., Sodowski M., Wylezol M., Kuka D., Sowa P., Adamczyk-Sowa M., Kukla M., Berdowska A., Rehfeld J. F., Bielanski W., Brzozowski T.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
|
nr 1
13-35
13
Content available remote

Role of leptin, ghrelin, angiotensin II and orexins in 3T3 L1 preadipocyte cells proliferation and oxidative metabolism

52%
Zwirska-Korczala K., Adamczyk-Sowa M., Sowa P., Pilc K., Suchanek R., Pierzchala K., Namyslowski G., Misiolek M., Sadowski K., Kato I., Kuwahara A., Zabielski R.
Journal of Physiology and Pharmacology. Supplement
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2007
|
tom 58
|
nr 1
53-64
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