Preferencje help
Polish version English version Język
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 12

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
1
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

The effect of 2-Deoxy-D-Glucose on Glucose -6-Phosphate dehydrogenase activity in the cytoplasmic fraction of rat liver heart and skeletal muscles

100%
Ozegowski S., Torlinska T., Kozlik J.
Acta Physiologica Polonica
|
1988
|
tom 39
|
nr 1
2
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Effect of insulin and heparin on the activity of krebs cycle enzymes in mitochondrial fraction isolated from liver, skeletal muscle, and heart during hyperthermia in rat

100%
Kozlik J., Torlinska T., Paluszak J.
Acta Physiologica Polonica
|
1988
|
tom 39
|
nr 1
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Effect of hypothermia on the insulin - receptor interaction in adipose plasma membranes

100%
Torlinska T., Mackowiak P., Nogowski L., Kozlik J.
Journal of Physiology and Pharmacology
|
1995
|
tom 46
|
nr 3
4
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Effect of hypothermia on the insulin - receptor interaction in liver plasma membranes

100%
Torlinska T., Nowak K. W., Kozlik J., Paluszak J.
Journal of Physiology and Pharmacology
|
1993
|
tom 44
|
nr 4
5
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Effect of hypothermia on the insulin - receptor interaction in skeletal muscle plasma membranes

100%
Torlinska T., Mackowiak P., Nogowski L., Kozlik J.
Journal of Physiology and Pharmacology
|
1996
|
tom 47
|
nr 2
6

Somatostatin effect on the level of adenyl nucleotides in the blood and tissues of rats during short-lasting hypothermia

88%
Krauss H., Torlinska T., Paluszak J., Kruk D., Kozlik J.
Acta Physiologica Polonica
|
1983
|
tom 34
|
nr 4
7
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Triiodothyronine effect on some parameters of carbohydrate metabolism in rats blood and liver. I. In vivo effect of triiodothyronine on liver glycogen content, blood metabolites and serum glycogenolytic activity

76%
Torlinska T., Grzymislawski M., Paluszak J., Sosnowski P., Torlinski L., Kozlik J.
Acta Physiologica Polonica
|
1987
|
tom 38
|
nr 4
8

Influence of bradykinin and ACE inhibitors on selected biochemical markers of oxidative stress in rats with induced ischemia-reperfusion syndrome

76%
Krauss H., Sosnowski P., Grzymislawski M., Kozlik J., Jablecka A., Balcer N., Bednarek A.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 09
1052-1056
Cessation of blood flow in tissues leads to depletion of energetic resources of cells, disturbances in the activity of enzymes of the oxidative chain and electrolyte disorders, as well as to the production of reactive oxygen species. A great deal of attention has been paid to those problems since they are responsible for most of the complications in the ischemia-reperfusion (I/R) syndrome. Understanding the antioxidative mechanisms involved in I/R syndrome provides us with the potential to correct at least some of the resulting disturbances. One of the potentially beneficial factors is insulin. This observation directed our attention to the insulin-like factors, kinins (especially bradykinin), the activation of which was detected in I/R syndrome. The effect of bradykinin is modified by concurrent administration of the specific antagonists of bradykinin receptors, B1 and B2. The aim of the current study was to assess the role of bradykinin. In the study, the employed agents included the angiotensin converting enzyme inhibitor, which prevents the degradation of endogenous kinins, and blockers of bradykinin receptors, which abolish the influence of kinins. We observed that after 4 hours of ischemia followed by reperfusion, levels of free radicals in tissues as well as levels of peroxides in plasma increased significantly. Administration of bradykinin, captopril or enalapril resulted in the decline of these free radical levels. The application of B2 receptor antagonist decreased the beneficial influence of bradykinin, whereas B1 receptor antagonist revealed no significant effect. Activities of antioxidative enzymes (superoxide dismutase, catalase, and glutathione peroxidase) were measured. After 4 hours of ischemia and consecutive steps of reperfusion, a statistically significant increase in their activities was observed when bradykinin or ACE inhibitors were administered. Application of B2 receptor blockers reduced the effect of bradykinin, whereas the effect of B1 receptor antagonists was minute.
9

The influence of the kallikrein-kinin system on the characteristics of insulin receptors in rat skeletal muscle during ischemia

76%
Mackowiak P., Krauss H., Kozlik J., Sosnowski P., Paluszak J., Mikrut K., Torlinska T.
Journal of Animal and Feed Sciences
|
1998
|
tom 07
|
nr 1
93-100
10
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

The effect of 4-aminopyrazolo (3,4-d) pyramidine (4-APP) on some parameters of carbohydrate metabolism in the rat

76%
Torlinska T., Malendowicz L. K., Paluszak J., Kozlik J., Nowak M., Nowak K. W., Godlewski J.
Acta Physiologica Polonica
|
1989
|
tom 40
|
nr 5-6
Torlińska, T., Malendowicz, L. K, Paluszak, J., Koźlik, J., Nowak, M., Nowak, K. W. and Godlewski, J.: The effect of 4-aminopyrazolo (3,4-d) pyrimidine (4-APP) on some parameters of carbohydrate metabolism in the rat. Acta physiol, pol., 1989, 40 (5-6): 530-534. The study was designed to evaluate some parameters of carbohydrate metabolism in the rat as influenced by 4-APP, an adenine analogue. Adult female rats were injected with 1 mg 4-APP /100 g body weight/ day for 3 days. 4-APP evoked a marked enlargement of the liver with lipid droplets accumulation in hepatocytes. This was accompanied by a marked lowering of the liver glycogen content. Within 3 days 4-APP did not change serum glucose, insulin and free fatty acid concentration. Serum glycogenolytic activity studied in an in vitro system showed 7 times as high glucose releasing ability in 4-APP treated rats as that of the serum of control animals. 4-APP resulted also in a marked enlargement of the adrenal medulla and lowered adrenaline and noradrenaline concentrations in the gland. The possibility of an activation of glycogenolysis in the liver of 4-APP treated rats has been discussed.
11

Effect of insulin and beta-adrenergic blockade on certain indicators of carbohydrate metabolism in the blood and tissues of rats during short-lasting hypothermia

76%
Torlinska T., Paluszak J., Gryczka A. Z., Torlinski L., Walkowiak K., Kozlik J.
Acta Physiologica Polonica
|
1982
|
tom 33
|
nr 4
12

Influence of bradykinin on the course of ischemia-reperfusion syndrome

64%
Krauss H., Biczysko W., Majewski P., Grzymislawski M., Sosnowski P., Kozlik J., Jablecka A., Bednarek A., Balcer N.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 08
914-918
Acute ischemia and the subsequent reperfusion caused by temporary closure of blood flow in the main arteries, which activate generalized inflammatory response, lead to endothelial injury. The aim of the study was to examine the injury of tissues in the ischemia reperfusion syndrome. Additionally, we tried to estimate the role of B1 and B2 bradykinin-receptor antagonists. In our study we histologically assessed specimens of lungs, kidney, liver, small and large intestine and skeletal muscle from the thigh. We compared the samples obtained from the groups of animals that were exposed to 4 hours of complete ischemia and 120 minutes of reperfusion. We divided animals into 4 groups. Rats in the first group were the control group, animals from the second received bradykinin. In the third and fourth group respectively bradykinin along with B2 and B1 bradykinin-receptor antagonist were administered. The results of microscopic examination revealed that bradykinin exerts a protective effect on the function and structure of distant organs as well as the skeletal muscle which was subjected to ischemia and reperfusion. The most visible effects of bradykinin were found in the samples of the lung, skeletal muscle, and the large and small intestines. Administration of bradykinin receptor antagonists, especially B2 receptor blocker, reduces the advantageous effects of bradykinin. The conclusion of our study is that administration of bradykinin may be beneficial in diseases accompanied by limb ischemia where tissue blood flow and oxygen metabolism are dependent upon kinin release, which in turn will condition tissue repair.
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.