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Evaluation of CD40 and CD80 receptors in the colonic mucosal membrane of children with inflammatory bowel disease

100%
Kaminska B., Roszko-Kirpsza I., Landowski P., Szlagatys-Sidorkiewicz A., Guzinska-Ustymowicz K., Maciorkowska E.
Annals of Agricultural and Environmental Medicine
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2015
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tom 22
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nr 4
2

Diagnosis and treatment difficulties in 18-year-old male patient with hereditary hemochromatosis, chronic hepatitis B, Gilbert syndrome and ulcerative colitis

100%
Sikorska K., Liberek A., Romanowski T., Szlagatys-Sidorkiewicz A., Landowski P., Bielawski K. P.
Acta Biochimica Polonica
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2011
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tom 58
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nr 2
Among possible causes of chronic hepatitis in adolescents most common are infections, autoimmune disorders and metabolic diseases. Thus, diagnostic procedures should be multidirectional. This study reports diagnosis and treatment difficulties in an 18-year-old male patient with hereditary hemochromatosis (HH), ulcerative colitis (UC), chronic hepatitis B (CHB) and Gilbert syndrome. The presented case illustrates problems in diagnostics related to the presence of numerous disease conditions in one patient. It should be taken into consideration that these diseases coexisting in one patient can mutually affect their symptoms creating specific diagnostic difficulties.
3

Coexistence of type 1 diabetes mellitus and spinal muscular atrophy in an 8-year-old girl:a case report

100%
Borkowska A., Jankowska A., Szlagatys-Sidorkiewicz A., Sztangierska B., Liberek A., Plata-Nazar K., Kaminska B.
Acta Biochimica Polonica
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2015
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tom 62
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nr 1
4

Serum chemerin level, cytokine profile and nutritional status in children with cystic fibrosis

100%
Sznurkowska K., Kazmierska K., Sledzinski T., Zagierski M., Liberek A., Szlagatys-Sidorkiewicz A.
Acta Biochimica Polonica
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2019
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tom 66
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nr 4
5

TGF-beta1, IL-10 and IL-4 in colostrum of allergic and nonallergic mothers

84%
Marek A., Zagierski M., Liberek A., Aleksandrowicz E., Korzon M., Krzykowski G., Kaminska B., Szlagatys-Sidorkiewicz A.
Acta Biochimica Polonica
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2009
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tom 56
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nr 3
411-414
Objective: To determine transforming growth factor (TGF) β1, interleukin (IL) 4, and IL-10 concentrations in human milk and to assess the relationship between allergic disorders in mothers and the content of the interleukins in their milk. Material and methods: Thirty allergic and 46 healthy mothers were included in the study. Colostrum was collected 2-3 days after delivery. Cytokine concentrations were determined with commercial enzyme-linked immunosorbent systems. Results: TGF-β1was found in milk from 23 women in the control group (53.49%) and 11 in the allergy group (37.93%). When TGF-β1 was present, the median concentration was higher in the allergy group than in the control (61.5 and 30.4 pg/mL, respectively; P < 0.004). IL-10 was present in the colostrum of all the women and the median IL-10 concentration did not differ between the allergy (50.5 pg/mL) and control (51.5 pg/mL) groups. The probability of occurrence of a positive IL-4 value in the allergy group was greater than in the control group (chi-squared [df = 1] = 2.60, P < 0.053). Median IL-4 level did not differ significantly between the two groups (0.5 and 0.5 pg/mL respectively). Conclusions: TGF-β1 was detected less often in the colostrum of allergic mothers than in that of mothers without allergy (but the difference was not statistically significant). IL-4 was found more often in the colostrum of allergic mothers than nonallergic ones. The allergy status did not correlate with IL-10 concentration.
6

Peripheral regulatory T cells and anti-inflammatory cytokines in children with juvenile idiopathic arthritis

84%
Sznurkowska K., Bockowska M., Zielinski M., Plata-Nazar K., Trzonkowski P., Liberek A., Kaminska B., Szlagatys-Sidorkiewicz A.
Acta Biochimica Polonica
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2018
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tom 65
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nr 1
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