The Tournaisian and early Viséan (Carboniferous) faunas of Britain have been divided into a sequence of four assemblage biozones, the Vaughania vetus, Zaphrentites delanouei and Caninophyllum patulum assemblage biozones which are of Tournaisian age, and the Siphonophyllia cylindrica Assemblage Biozone of Viséan (Chadian) age. This sequence of biozones established at Burrington Combe in the Mendips is used to correlate the Tournalsian and early Viséan rocks from eight sections in the Bristol and South Wales areas. Several sections can be shown to be incomplete with a northward widening non-sequence present between the top of the Black Rock Limestone and the base of the succeeding Gully Oolite. One new species Sychnoelasma clevedonensis sp.n. and one new subspecies Caninophyllum patulum greeni sub-sp.n. are named.
In a group of 194 persons aged 54–86 years global DNA methylation was determined using Imprint DNA Quantification KitMDQ1 (Sigma-Aldrich). The association with several biochemical factors as serum glucose,serum creatinine and folic acid (determined by chemiluminescence) levels as well as with sex, age and cognitive status was estimated by multivariate stepwise regression analysis. The strongest association was stated with serum creatinine (P=0.0003), with serum folic acid (P=0.005) and with glucose (0.008) levels. The mechanisms and significance of these associations is discussed in view of human aging and age-connected diseases as atherosclerosis, diabetes and renal failure
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