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NBL 1 and anillin [ANLN] genes over-expression in pancreatic carcinoma

100%

Olakowski M., Tyszkiewicz T., Jarzab M., Krol R., Oczko-Wojciechowska M., Kowalska M., Kowal M., Gala G. M., Kajor M., Lange D., Chmielnik E., Gubala E., Lampe P., Jarzab B.

Folia Histochemica et Cytobiologica

2009

tom 47

nr 2

249-255

Gene expression profile analysis in laryngeal cancer by high-density oligonucleotide microanalysis

100%

Markowski J., Oczko-Wojciechowska M., Gierek T., Jarzab M., Paluch J., Kowalska M., Wygoda Z., Pfeifer A., Tyszkiewicz T., Jarzab B., Niedzielska I., Borgiel-Marek H.

Journal of Physiology and Pharmacology. Supplement

2009

tom 60

nr 1

57-63

The assessment of gene expression profile in laryngeal cancer shall allow to implement molecular biology methods in diagnostics, as well as in prognosis of the course of disease. Thus, it may influence the choice of the most optimal decisions in regards to the method of treatment, extent of surgical procedure, or the necessity of adding post-operative radiotherapy. The aim of the project was to analyse the gene expression profile of laryngeal cancer using oligonucleotide microarrays, aiming to derive novel molecular markers for that carcinoma. The study comprised a group of 14 patients (12 males and 2 females) with squamous cell laryngeal carcinoma, diagnosed and surgically treated between 2005 – 2007 in the ENT Department of the Silesian Medical University in Katowice, Poland. RNA was isolated from frozen tissue fragments. To assess gene expression profile, high density oligonucleotide microarrays (Affymetrix U 133 Plus 2.0) were applied, with over 54 thousand probesets for over 47 thousand transcripts. Four genes, previously not assesed in diagnostic context in laryngeal carcinoma, seemed to be valuable markers of that neoplasm. These are: metalloproteinase ADAM12, cycline-dependent kinase 2 - CDK2, kinesine 14 - KIF14, suppressor 1 of checkpoint - CHES1.

Ratio of proliferation markers and HSP90 gene expression as a predictor of pathological complete response in breast cancer neoadjuvant chemotherapy

88%

Jarzab M., Kowal M., Bal W., Oczko-Wojciechowska M., Rembak-Szynkiewicz J., Kowalska M., Stobiecka E., Chmielik E., Tyszkiewicz T., Kaszuba M., Nowicka E., Lange B., Czarniecka A., Krajewska J., Dyla A., Dobrut M., Lange D., Jarzab B., Bobek-Billewicz B., Tarnawski R.

Folia Histochemica et Cytobiologica

2016

tom 54

nr 4

Epidermal differentiation complex (locus 1q21) gene expression in head and neck cancer and normal mucosa

88%

Tyszkiewicz T., Jarzab M., Szymczyk C., Kowal M., Krajewska J., Jaworska M., Fraczek M., Krajewska A., Hadas E., Swierniak M., Markowski J., Lange D., Poltorak S., Wiench M., Krecicki T., Jarzab J., Maciejewski A.

Folia Histochemica et Cytobiologica

2014

tom 52

nr 2

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Wyniki wyszukiwania

NBL 1 and anillin [ANLN] genes over-expression in pancreatic carcinoma

Gene expression profile analysis in laryngeal cancer by high-density oligonucleotide microanalysis

Ratio of proliferation markers and HSP90 gene expression as a predictor of pathological complete response in breast cancer neoadjuvant chemotherapy

Epidermal differentiation complex (locus 1q21) gene expression in head and neck cancer and normal mucosa