Wyniki wyszukiwania

1

Anatomy of sartorius muscle

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Dziedzic D., Bogacka U., Ciszek B.

Folia Morphologica

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2014

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tom 73

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nr 3

A sartorius muscle is the longest muscle of the human system. It runs over 2 joints — hip and knee joints. In the study 10 sartorius muscles were examined. They were dissected free of lower human limbs. Dimensions of limbs which these muscles come from and dimensions of the muscles and their component parts were examined. The attention was paid mainly to parts of tendon located inside the muscle belly. The results show that they are either of a comparable length (distal tendon) or several times longer (proximal tendon) than visible parts located outside of the muscle. Moreover, a complex structure of the distal tendon which includes 2 tracts of different places of insertion was stated. Inferior tract inserted in the same place as muscle tendons: semitendinosus and gracilis. The superior tract inserted transversely against the former one. The tendon of the sartorius muscle forms additionally an aponeurosis whose fibres enter into the deep fascia of crus. The muscle belly is characterised with various width on different levels of its length. In half of cases sword-like distal segment of belly is formed. (Folia Morphol 2014; 73, 3: 359–362)

2

Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis

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Dziedzic D., Narajczyk M., Gabig-Ciminska M., Jakobkiewicz-Banecka J.

Acta Biochimica Polonica

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2012

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tom 59

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nr 2

It has been demonstrated recently that it is possible to decrease expression of genes coding for enzymes involved in synthesis of glycosaminoglycans (GAGs) by using specific siRNAs which interfere with stability of particular mRNAs. This procedure has been proposed as a potential treatment for patients suffering from mucopolysaccharidoses, a group of inherited metabolic diseases caused by dysfunction of enzymes required for GAG degradation, and resultant storage of these compounds in cells of affected persons. Here, we asked if the simultaneous use two species of specific siRNAs aimed at silencing two genes involved in particular steps of GAG synthesis may be more effective than the use of single siRNA. We found that inhibition of GAG synthesis in cells treated with two siRNAs is generally more effective than using single siRNAs. However, the differences were not statistically significant, therefore the potential benefit from the use of two siRNAs over the use of a single siRNA is doubtful in the light of the cost-benefit ratio and possibly stronger side-effects of the putative therapy.

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Anatomy of the long peroneal muscle of the leg

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Bogacka U., Dziedzic D., Komarnitki I., Ciszek B.

Folia Morphologica

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2017

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tom 76

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nr 2

Background: The aim of the work was to perform a morphometric analysis of the long peroneal muscle (LPM) of the leg and explore the relationship between muscle belly and tendon. Materials and methods: Ten lower limbs (8 right and 2 left) were fixed in formaldehyde and dissected using standard technique. The LPM was exposed from the proximal attachment to the top of a lateral malleolus. Results: The tendon was subsequently freed and various measurements were taken. The tendon of the LPM enters deep into the muscle belly. Muscle fibres surround the tendon and descend as far down as 4 cm above the lateral malleolus. Muscle fibres insert mainly along posterior border of the tendon and on its medial surface, leaving lateral surface only partly covered. Conclusions: The LPM contains a long intramuscular segment of the tendon and area of the musculotendinous junction varies along the LPM. It makes the idea of uniform pennation pattern of the LPM unlikely. (Folia Morphol 2017; 76, 2: 284–288)

4

Flow cytometric analysis of CD133- and EpCAM-positive cells in the peripheral blood of patients with lung cancer

88%

Skirecki T., Hoser G., Kawiak J., Dziedzic D., Domagala-Kulawik J.

Archivum Immunologiae et Therapiae Experimentalis

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2014

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tom 62

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nr 1

Ograniczanie wyników

2 Folia Morphologica

1 Acta Biochimica Polonica

1 Archivum Immunologiae et Therapiae Experimentalis

4 Dziedzic D.

2 Bogacka U.

2 Ciszek B.

1 Domagala-Kulawik J.

1 Gabig-Ciminska M.

1 Hoser G.

1 Jakobkiewicz-Banecka J.

1 Kawiak J.

1 Komarnitki I.

1 Narajczyk M.

1 Skirecki T.

1 2017

2 2014

1 2012

Anatomy of sartorius muscle

Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis

Anatomy of the long peroneal muscle of the leg

Flow cytometric analysis of CD133- and EpCAM-positive cells in the peripheral blood of patients with lung cancer